Monoplegia is a kind of paralysis in which only one limb, an arm or a leg, has lost complete voluntary muscle movement. The condition can be temporary or permanent. Cerebral palsy is the most common cause of monoplegia. Treatment typically involves managing your symptoms to improve your quality of life.
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Monoplegia occurs when something, like a stroke or an injury, disrupts the nerve signals to the muscles in your arm or leg. It’s a type of paralysis that affects one arm or leg. Paralysis means you can’t move a part of your body. Monoplegia is sometimes temporary, but it’s often permanent.
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A problem with your nervous system causes monoplegia. Your nervous system is your body’s command and communication system. It sends signals from your brain throughout your body, telling it what to do. If something damages your nervous system, messages can’t get through to the muscles in your arm or leg. The message has to go from your brain to your spinal cord, nerve roots, nerves and then your muscles. So, there are a lot of places that monoplegia could come from.
The inability to move one of your arms or legs is the most common symptom of monoplegia. Other symptoms that happen with monoplegia that may affect your arm or leg include:
Symptoms may come on suddenly if you had an injury or experienced a stroke. Symptoms come on gradually if you have a disease like cerebral palsy.
The most common cause of monoplegia is cerebral palsy. Cerebral palsy is a neurological condition that occurs when the areas of your brain that control muscle movement don’t develop properly or receive damage. This is a condition you’re born with.
Other monoplegia causes may include:
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Monoplegia can lead to blood clots and other circulatory disorders like deep vein thrombosis (DVT) in the affected limb. The condition can cause disability. This may affect your mental health, possibly leading to conditions like depression and anxiety.
A healthcare provider will perform a physical exam and ask you if you’ve had any recent injuries. They’ll talk to you about when you first started to notice the problem. Your provider may request certain tests, including:
There isn’t a cure for monoplegia, but your provider will do what they can to treat the underlying cause. Treatment mainly focuses on relieving your symptoms and improving your quality of life.
Treatment options may include different kinds of therapy, like:
In addition to therapy, your provider may recommend assistive devices, like a wheelchair, crutches or a scooter to help you get around.
Depending on your condition, medications like pain relievers and muscle relaxants may help relieve some of your symptoms. If you have spasms or curling up of your limb, botulinum toxin injections can help.
In some cases, your provider may recommend surgery to correct anatomical abnormalities.
If you have signs of a stroke or a possible head, neck or spine injury, you should call 911 or your local emergency number. Otherwise, call your provider if you have:
You may want to ask your provider:
The outlook for monoplegia depends on the cause and severity. The condition can sometimes improve over time, but many people will have permanent paralysis. Treatment can help reduce your symptoms and improve your quality of life.
Monoplegia and monoparesis are similar, but they refer to different types of paralysis. Monoplegia means you have a complete loss of voluntary motor function in your arm or leg. Monoparesis means you’ve only partially lost function in your arm or leg.
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Monoplegia refers to paralysis that affects a single limb — one arm or one leg. Hemiplegia is paralysis that affects one entire side of your body (the entire right side of your body or the entire left side of your body). It affects the muscles in your arms, legs and sometimes face.
Monoplegia can be life-changing. You’ll need to adjust the way you do things — even if your paralysis is temporary. And it’s OK to have a lot of feelings about that. But know that there are treatments that can help relieve some of your symptoms and improve your quality of life. Talk to your healthcare provider about what options are available to you.
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If you have a neurological condition, you want expert advice. At Cleveland Clinic, we’ll work to create a treatment plan that’s right for you.
Last reviewed on 02/25/2025.
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