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Malignant Neoplasm

Medically Reviewed.Last updated on 02/02/2022.

Malignant neoplasms are cancerous tumors. They develop when cells grow and divide more than they should. Malignant neoplasms can spread to nearby tissues and to distant parts of your body. Treatment options may include surgery, chemotherapy or radiation therapy. Early detection is key, so be sure to attend all recommended cancer screenings.

What Is A Malignant Neoplasm?

A malignant neoplasm is a cancerous tumor. These tumors can start in different parts of our body. They may grow and spread
Malignant neoplasms are cancerous tumors that may start in different parts of your body.

A malignant neoplasm is a cancerous tumor. It may grow, invade surrounding tissue and/or spread to other parts of your body. A fast-growing tumor that spreads may be life-threatening.

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Types of malignant neoplasms

Malignant neoplasms form when cancerous cells multiply to form masses of abnormal tissue. Common types are:

  • Blood cancersThese are malignant neoplasms that affect your blood cells.
  • CarcinomasThese are malignant neoplasms in the lining of your organs or your skin.
  • SarcomasThese malignant neoplasms begin in your bones or connective tissue like your cartilage, muscle, tendons and fat.

Symptoms and Causes

Symptoms of a malignant neoplasm

Symptoms vary depending on the cancerous tumor’s location. For example, breast cancer (malignant neoplasm in your breast) may cause a lump, pain or changes in breast skin. Prostate cancer (malignant neoplasm of the prostate) may cause blood in your pee or cause you to pee more often.

Some general symptoms include:

  • Fatigue
  • Shortness of breath
  • Persistent cough
  • Diarrhea
  • Unexpected weight loss
  • Drenching night sweats
  • Abnormal lumps or bumps

What causes malignant neoplasms?

These tumors form when cells multiply and divide faster than they should. Unlike normal cells, cancerous cells don’t die. Cancer happens when genetic mutations turn normal cells into cancerous cells. The risk of cancer increases as you age. Certain issues or activities increase your risk. Those include:

  • Smoking
  • Genetics
  • Obesity
  • Excessive alcohol use
  • Chemical toxins
  • Excessive exposure to radiation
  • Excessive exposure to ultraviolet (UV) rays

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Complications

The cancerous cells that form malignant neoplasms can move through your blood or lymphatic system to affect other parts of your body. This is metastasis. Malignant neoplasms can spread anywhere in your body, but typically develop in your bones, brain, liver and lungs. Cancer that spreads from where it started is more difficult to treat.

Diagnosis and Tests

How doctors diagnose this condition

A healthcare provider may do a CT scan or an MRI scan to look for cancer. They’ll do a biopsy to get tissue samples if they detect a possible tumor. A medical pathologist checks the samples for abnormal cells. They examine the cells for changes in cell sizes and shapes. A biopsy is the only way providers can be sure a neoplasm is cancer.

What questions should I ask about my diagnosis?

Your healthcare provider will explain where a malignant neoplasm is located, the cancer stage and grade, and the treatment options they recommend. Asking questions will help you feel more confident as you make treatment decisions.

Management and Treatment

How is a malignant neoplasm treated?

Treatment focuses on preventing the malignant neoplasm from growing or spreading. Your healthcare provider may discuss treatments like surgery, chemotherapy, immunotherapy and/or radiation therapy.

If you have surgery, you may have other cancer treatments before or after surgery:

  • Neoadjuvant therapy: These treatments shrink large tumors so they’re easier to remove during surgery.
  • Adjuvant therapy: This is follow-up treatment to kill any remaining cancer cells.

Outlook / Prognosis

What can I expect if I have this condition?

Your prognosis (outlook) depends on your situation, including the type of tumor, stage and location. For example, surgery may cure cancer if you have surgery to remove a small tumor that hasn’t spread. It’s more challenging to successfully treat metastatic cancer. And some malignant tumors may come back. Your healthcare provider will take time to explain any next steps after treatment so you know what to expect. 

Is there anything I can do to feel better?

There’s nothing easy about learning that you have a malignant neoplasm. Fortunately, there are special treatments that may help:

  • Cancer rehabilitationThis helps you be in the best shape possible before you start treatment. You may have nutritional support, physical therapy and mental health support.
  • Cancer survivorship: This is support to help you have the best quality of life throughout your experience with cancer.
  • Palliative careYour care team can help you manage symptoms and treatment side effects.

Having cancer may make you feel isolated or alone. It may help to spend time or talk to other people in your situation. Your healthcare provider can help find support groups or other community resources.

Prevention

Can a malignant neoplasm be prevented?

There’s no way to prevent one from developing. But there are things you can do to reduce your risk:

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  • Don’t smoke.
  • Protect your skin when you go outside.
  • Limit the amount of alcohol you drink.
  • Maintain a healthy lifestyle by eating well and exercising often.
  • Get cancer vaccines like HPV for cervical cancer or the hepatitis B vaccine for liver cancer.
  • Ask your healthcare provider about cancer screenings.
  • Consider genetic testing if you have a family history of malignant neoplasms.

While you can’t prevent this condition, early diagnosis and treatment may make a difference. Take time to get to know your body. Talk to a healthcare provider if you notice changes like a lump that doesn’t go away, blood in your poop or you’re losing weight without trying.

Additional Common Questions

What is the difference between neoplasm and cancer?

A neoplasm is an abnormal growth of tissue that can be benign (noncancerous) or malignant (cancerous). Benign tumors (noncancerous neoplasms) usually grow slowly and don’t spread. However, malignant tumors (cancerous neoplasms) typically grow rapidly and invade other parts of your body.

A note from Cleveland Clinic

Tests show you have a malignant neoplasm. You may have a fast-growing tumor that’s spreading. Often, treatment can manage the condition. Even so, it can be challenging to manage cancer symptoms and treatment.

Don’t hesitate to lean on your cancer care team for support. They know and understand a cancer diagnosis may make you feel anxious or depressed. You may feel isolated and lonely. Ask your team for help, whether it’s getting mental health support or connecting with a support group.

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Medically Reviewed.Last updated on 02/02/2022.

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References

Cleveland Clinic’s health articles are based on evidence-backed information and review by medical professionals to ensure accuracy, reliability and up-to-date clinical standards.

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