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Henoch-Schönlein Purpura (IgA Vasculitis)

Henoch-Schönlein purpura (HSP) is a type of vasculitis that causes a distinctive reddish-purple rash on your child’s skin. The rash may occasionally itch but doesn’t hurt. The condition causes other uncomfortable symptoms. Fortunately, the symptoms usually go away on their own within a few months. HSP may also be known as IgA vasculitis.

What Is Henoch-Schönlein Purpura?

Henoch-Schönlein purpura (HSP) is a type of vasculitis. Vasculitis is a condition that causes irritation and swelling in your blood vessels. In the HSP form of vasculitis, the swelling usually affects the small blood vessels in your skin. But it can also affect your kidneys, intestines and joints.

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HSP occurs when an antibody in your immune system called immunoglobulin A builds up in your blood vessels. This buildup causes your blood vessels to burst and leak blood under your skin. This leads most people to develop a spotty, purplish skin rash that looks like small bruises or pools of blood.

HSP is a clinical form of immunoglobulin A vasculitis (IgA vasculitis). Healthcare providers name it after the antibody that causes it. The condition can affect anyone. But it most often affects children.

IgA vasculitis usually isn’t serious. Most children recover from it on their own without treatment. Henoch-Schönlein purpura in adults can be more severe. If it affects your kidneys, you may need treatment to prevent long-term complications.

Symptoms and Causes

A child with the distinct rash of Henoch-Schönlein purpura on their legs
Henoch-Schönlein purpura is a type of vasculitis that causes a spotty, reddish-purple skin rash.

Symptoms of Henoch-Schönlein purpura

HSP symptoms can affect your child’s skin, joints, intestines and kidneys. The most common symptom is the Henoch-Schönlein purpura rash. This reddish-purple rash causes spotty, raised bumps on your child’s skin. There may be many spots or just a few. But it isn’t painful, and it usually doesn’t itch. It most commonly affects your child’s legs and butt.

Other symptoms of HSP disease may include:

  • Joint pain and swelling
  • Cramping belly pain that may come and go
  • Nausea and vomiting
  • Diarrhea
  • Blood in their pee
  • Blood in their poop

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HSP causes

HSP is an autoimmune disease. It occurs when your child’s immune system attacks their healthy blood vessels by mistake. Researchers don’t know why this happens. But about 50% of children have an upper respiratory infection just before the condition develops.

What are the triggers for Henoch-Schönlein purpura?

HSP may be an unusual reaction of your child’s immune system in response to:

  • Bacterial infections, like strep throat
  • Viral infections
  • Certain foods
  • Bug bites
  • Several medications
  • Some vaccines

Risk factors

IgA vasculitis can affect anyone at any age. But more than 90% of cases are diagnosed in children between the ages of 3 and 10 years old.

Other risk factors include:

  • Family history: You’re more at risk of developing HSP if someone in your biological family had it.
  • Ethnicity: The condition is more common in ancestral European and Asian people.

Complications of IgA vasculitis

Most people with HSP recover completely without treatment within three months. The condition may return but will usually go away on its own again. Sometimes IgA vasculitis can be severe and cause complications. This is even more likely in adults.

Complications of HSP disease may include:

  • Chronic kidney disease
  • Bleeding in your intestines
  • Bowel injury or blockage
  • High blood pressure during pregnancy

Diagnosis and Tests

How doctors diagnose IgA vasculitis

Your child’s pediatrician will perform a physical exam. They’ll look for the telltale rash and check for joint swelling. They’ll also ask you about your child’s other symptoms and medical history. Your child’s provider may request several tests to confirm the diagnosis.

Tests that are used

Tests to diagnose Henoch-Schönlein purpura may include:

  • Urinalysis
  • Blood tests
  • Kidney ultrasound
  • Abdominal ultrasound
  • Skin biopsy
  • Kidney biopsy

Management and Treatment

How is HSP treated?

Henoch-Schönlein purpura treatment consists of symptom relief at home. Your child may not need more than an over-the-counter (OTC) pain reliever to help with joint pain and swelling. You can try Tylenol® or an NSAID, like Advil®.

For more severe symptoms (abdominal pain, bleeding), your child’s provider may prescribe a steroid, like prednisone. If the rash and other symptoms don’t go away, see their pediatrician.

IgA vasculitis is most often a mild illness that goes away on its own. But it can cause serious complications in your child’s kidneys and intestines. Some children may need to take a medication that keeps their immune systems working correctly. It can help prevent these complications. Ask your child’s pediatrician about the side effects of these medications. That way, you can understand how they may affect your child.

Can Henoch-Schönlein purpura be self-healing?

Yes, most cases of HSP get better on their own without treatment. Symptoms of the condition can last up to three months. Most often, they go away after a month. While less common, symptoms may come back in the future or last longer than three months.

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When should my child see their healthcare provider?

Visit your child’s provider if they experience:

  • Abnormal swelling
  • Severe pain and discomfort
  • Symptoms that last longer than 12 weeks
  • Symptoms that go away and return
  • Symptoms that get worse instead of better

Outlook / Prognosis

Is HSP a lifelong disease?

No, HSP disease usually goes away within one to three months. For most children, it only occurs one time. Some children may experience a second episode. Symptoms are typically less severe the second time, and the condition often goes away on its own again.

Henoch-Schönlein purpura prognosis

Henoch-Schönlein purpura in children almost always has a very good outlook. Your child’s pediatrician will likely want your child to come in for follow-ups for a while to check for signs of kidney disease. While rare, long-term kidney damage can happen.

A note from Cleveland Clinic

Henoch-Schönlein purpura, or IgA vasculitis, can cause your child pain and discomfort. It may be a while before they feel better again. It hurts to see your child in pain. But most children make a full recovery without any long-term complications.

Treatment isn’t always necessary. But if you’re worried or your child is uncomfortable, visit their pediatrician. You can count on their provider to listen to your concerns and help your child find relief.

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Care at Cleveland Clinic

When your child is diagnosed with pediatric vasculitis, they’ll need expert care. And you’ll want the best team on their side. Cleveland Clinic Children’s is here for you.

Medically Reviewed

Last reviewed on 11/17/2025.

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