What is Lipedema?

Lipedema is a condition that causes excess fat to accumulate in the lower part of the body. Lipedema most often involves the buttocks, thighs and calves. The upper arms can also be affected. The condition does not affect the hands or feet.

Lipedema is sometimes confused with lymphedema, but these are different conditions. However, lipedema can lead to lymphedema.

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What causes lipedema?

The exact cause of lipedema is unknown. But the condition runs in families and may be inherited. The condition occurs almost exclusively in women, and usually starts or gets worse at the time of puberty, pregnancy or menopause. Because of this, there is likely a connection to hormones.Lipedema is not caused by obesity but more than half of patients with this condition are overweight or obese. Dieting can cause you to lose weight in your upper body without changing the areas affected by lipedema.Symptoms of lipedema include:

  • Fat build-up in buttocks, thighs, calves, and sometimes the upper arms. Diuretics, elevating your legs and support stockings do not help the affected areas. There is typically no swelling in feet, or hands unless the patient has chronic venous insufficiency or lymphedema.
  • Pain.
  • As the condition gets worse, lipedema can affect your ability to walk.
  • Many patients with lipedema have emotional symptoms, such as being embarrassed, anxious and depressed as the lower part of their body grows larger.
  • Over time, as more fat accumulates, it can block the lymphatic pathway. This causes a build-up of fluid called lymph. The condition is known as secondary lymphedema or lipo-lymphedema.

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