Locations:

Suprep Bowel Preparation Instructions

Bowel preparation before a colonoscopy actually starts days before, when you should stop taking certain medications or supplements. You need to follow the SUPREP instructions and be prepared to drink a lot of liquid.

For Cleveland Clinic patients: IF YOU DO NOT FOLLOW THESE DIRECTIONS, YOUR COLONOSCOPY WILL BE CANCELLED.

Advertisement

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy

Key instructions

  • Your bowel must be empty so that your doctor can clearly view your colon. Follow all of the instructions in this handout EXACTLY as they are written.
  • DO NOT eat any solid food the ENTIRE day before your colonoscopy. Drink only clear liquids.
  • Buy your bowel preparation at least five days before your colonoscopy.

Transportation on the day of your exam

A responsible person MUST BE PRESENT with you at Check In before your colonoscopy and MUST REMAIN in the endoscopy area until you are discharged. You are not allowed to drive, take a taxi or bus, or leave the Endoscopy Center alone. If you do not have a responsible driver (family member or friend) with you to take you home, your exam cannot be done with sedation and will be cancelled.

Please bring a list of all of your current medications, including any over-the-counter medications, with you.

Medications

If you take insulin, medications for diabetes or blood thinners, you must call the doctor who orders those medications for instructions on altering the dosage before your colonoscopy. Blood thinners include Coumadin® (warfarin); Plavix®(clopidogrel); Ticlid® (ticlopidine hydrochloride); Agrylin® (anagrelide); Xarelto® (Rivaroxaban); Pradaxa® (Dabigatran); Eliquis® (Apixaban); and Effient® (Prasugrel).

Advertisement

All other medications, including aspirin, should be taken the day of the exam with a sip of water.

Five (5) days before your colonoscopy

  • Do NOT take medicines that stop diarrhea, such as loperamide (Imodium®) or bismuth subsalicylate (Kaopectate®, Pepto-Bismol®).
  • Do NOT take fiber supplements, such as Metamucil®, Citrucel®, or Perdiem®.
  • Do NOT take products that contain iron, such as multivitamins (the label lists what is in the products).
  • Do NOT take Vitamin E.

Buy the prescription bowel preparation solution at your local pharmacy or drugstore pharmacy five days before your colonoscopy.

Three days before your colonoscopy

  • Do NOT eat high-fiber foods, such as popcorn, beans, seeds (flax, sunflower, quinoa), multigrain bread, nuts, salad/vegetables, or fresh and dried fruit.

One day before your colonoscopy

  • Only drink clear liquids the ENTIRE DAY before your colonoscopy. Do NOT eat any solid foods. Drink at least 8 ounces of clear liquids every hour after waking up. The chart shows what you can and cannot drink.

Clear Liquids (No Red Liquids)
Gatorade®, Pedialyte® or Powerade®
DO NOT DRINK
Alcohol
Clear broth or bouillon
DO NOT DRINK
Milk or non-dairy creamer
Coffee or tea (no milk or non-dairy creamer)
DO NOT DRINK
Noodles or vegetables in soup
Carbonated and non-carbonated soft drinks
DO NOT DRINK
Juice with pulp
Kool-Aid® or other fruit-flavored drinks
DO NOT DRINK
Liquid you cannot see through
Strained fruit juices (no pulp)
DO NOT DRINK
Jell-O®, Popsicles®, hard candy
DO NOT DRINK
Water
DO NOT DRINK

The bowel preparation solution will be consumed in two parts. Do NOT add ice, sugar or any flavorings to the solution.

Part 1 at 6 PM on the evening before your colonoscopy:

  • Pour ONE 6-ounce bottle of SUPREP® liquid into the mixing container.
  • Add cool water to the 16 oz. line on the container and mix.
  • Drink ALL the liquid in the container.
  • Drink two more 16-ounce glasses of water over the next hour (one hour).
  • You may continue to drink clear liquids until midnight.

Part 2 on the day of your colonoscopy:

  • Pour ONE 6-ounce bottle of SUPREP liquid into the mixing container.
  • Add cool water to the 16-ounce line on the container and mix.
  • Drink ALL of the liquid in the container.
  • You must drink two more 16-ounce glasses of water over the next hour (one hour).
  • You may continue drinking clear liquids up to three (3) hours before your procedure.

Advertisement

Medically Reviewed

Last reviewed on 03/01/2020.

Learn more about the Health Library and our editorial process.

Ad
Appointments 216.444.7000