Breast Cancer

Breast Cancer Treatment

Cleveland Clinic's Breast Cancer Program is committed to providing patients with the best possible prevention, detection, and treatment options for breast disease. Breast cancer patients throughout main campus, regional hospitals and family health centers all received standardized care through care path guides and tumor board review. A multidisciplinary team comprising radiologists, pathologists, surgeons, plastic surgeons, medical oncologists, radiation oncologists, nurses, genetic counselors, psychologists, physical therapists, and social workers collaborates with each patient to develop a tailored care plan at National Accreditation Program for Breast Centers accredited sites throughout northeast Ohio.

Five-Year Overall Survival of Female Patients With All Stagesᵃ of Breast Cancer (N = 12552)

2011-2021

ᵃAJCC stage I-IV breast cancer

Five-Year Overall Survival of Female Patients With Breast Cancer by Raceᵃ (N = 12146)

2011-2021

Number at RiskYear 1Year 2Year 3Year 4Year 5
Caucasian (N = 10553)87627526603746963394
African-American (N = 1593)13051111875675477

ᵃSelf-Reported

Five-Year Overall Survival of Female Patients With Breast Cancer by Hormone Receptor Status (N = 9988)

2011-2021

Number at RiskYear 1Year 2Year 3Year 4Year 5
ER/PR Negative (N = 1920)162513621132893669
ER/PR Positive (N = 8056)68256039508440593043

ER= estrogen receptor, PR= progesterone receptor

Five-Year Overall Survival of Female Patients With Breast Cancer by HER2 Status (N = 10285)

2011-2021

Number at RiskYear 1Year 2Year 3Year 4Year 5
HER2 Negative (N = 8729)72446253513039862964
HER2 Positive (N = 1556)135811911007815610

HER2= human epidermal growth factor receptor 2

Five-Year Overall Survival of Female Patients With Stages I-III Breast Cancer by Estrogen Receptor, Progesterone Receptor, and HER2 Status (N = 9454)

2011-2021

Number at RiskYear 1Year 2Year 3Year 4Year 5
ER/PR Positive (N = 6995)58245143432734402542
HER2 Positive (N = 1336)11771043890727548
Triple-Negative (N = 1123)944781635491362

ER= estrogen receptor, HER2= human epidermal growth factor receptor 2, PR= progesterone receptor

Five-Year Overall Survival of Female Patients With Stage IV Breast Cancer by Estrogen Receptor, Progesterone Receptor, and HER2 Status (N = 544)

2011-2021

Number at RiskYear 1Year 2Year 3Year 4Year 5
ER/PR Positive (N = 341)2542031349061
HER2 Positive (N = 133)9976513626
Triple Negative (N = 70)34191394

ER= estrogen receptor, HER2= human epidermal growth factor receptor 2, PR= progesterone receptor

Five-Year Overall Survival of Female Patients With Stageᵃ 0 and I Breast Cancer (N = 7942)

2011-2021

Number at RiskYear 1Year 2Year 3Year 4Year 5
Stage 0 CC (N = 1965)1681149712401000751
Stage I CC (N = 5977)48214113321424621823

CC= Cleveland Clinic, NCDB= National Cancer Database

ᵃAJCC stage I-IV breast cancer

ᵇReference group data from the National Cancer Database (Commission on Cancer of the American College of Surgeons and the American Cancer Society) 2000-2002, as reported in: Edge SB, Byrd DR, Compton CC, Fritz AG, Greene FL, Trotti A. AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer Science & Business Media; 2010.

Five-Year Overall Survival of Female Patients With Stageᵃ IIA and IIB Breast Cancer (N = 3608)

2011-2021

Number at RiskYear 1Year 2Year 3Year 4Year 5
Stage IIA (N = 2455)2186196316961377974
Stage IIB (N = 1153)1007868728574411

CC= Cleveland Clinic, NCDB= National Cancer Database

ᵃAJCC stage I-IV breast cancer

ᵇReference group data from the National Cancer Database (Commission on Cancer of the American College of Surgeons and the American Cancer Society) 2000-2002, as reported in: Edge SB, Byrd DR, Compton CC, Fritz AG, Greene FL, Trotti A. AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer Science & Business Media; 2010.

Five-Year Overall Survival of Female Patients With Stageᵃ IIIA and IIIB Breast Cancer (N = 937)

2011-2021

Number at RiskYear 1Year 2Year 3Year 4Year 5
Stage IIIA (N = 602)532462386299203
Stage IIIB (N = 335)2541911257958

CC= Cleveland Clinic, NCDB= National Cancer Database

ᵃAJCC stage I-IV breast cancer

ᵇReference group data from the National Cancer Database (Commission on Cancer of the American College of Surgeons and the American Cancer Society) 2000-2002, as reported in: Edge SB, Byrd DR, Compton CC, Fritz AG, Greene FL, Trotti A. AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer Science & Business Media; 2010.

Five-Year Overall Survival of Female Patients With Late-Stage Breast Cancer (N = 794)

2011-2021

Number at RiskYear 1Year 2Year 3Year 4Year 5
Stage IIIC (N = 219)1851451088357
Stage IV (N = 575)38928719112472

CC = Cleveland Clinic, NCDB = National Cancer Database

ᵃAJCC stage I-IV breast cancer

ᵇReferance group data from the National Cancer Database (Commission on Cancer of the American College of Surgeon and the American Cancer Society) 2000-2002, as reported in: Edge SB, Byrd DR, Compton CC, Fritz AG, Greene FL, Trotti A. AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer Science & Business Media; 2010