Benign Bone Tumors

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Benign tumor fundamentals

Fortunately, the majority of tumors that originate in the bones are benign, meaning that the tumor is very unlikely to spread from its original site to a new location.

Contrary to what most people expect, benign bone tumors occur most often in people less than 30 years old. Most are discovered in children, while their skeletons are still growing. These tumors are often strongly influenced by the hormones that stimulate normal growth. As a result, many benign tumors actually stop growing once a child reaches skeletal maturity (i.e. when bones stop growing in length). This usually occurs between the ages 14-16 in girls and the ages of 16-19 in boys.

Among the most common benign tumors involving bone are endochondroma, osteochondroma, nonossifying fibroma, chondroblastoma, osteoid osteoma, osteoblastoma, periosteal chondroma, giant cell tumor, and chondromyxoid fibroma. Some conditions such as aneurysmal bone cyst, unicameral bone cyst, and fibrous dysplasia are sometimes grouped with benign bone tumors. They often require similar treatment, but are not truly tumors.

Benign tumors can occur in any bone of the skeleton. Some types of tumors are most common in specific locations such as the spine or near the growth plates of the largest bones. In general, the most common bones involved are also the largest, the femur, tibia, humerus, and pelvis.

Some “benign” tumors occasionally are locally aggressive tumors that can progressively destroy bone.  An example would be giant cell tumor of bone.  This particular tumor would need early local management before the end of a bone is destroyed.

What are the symptoms?

A palpable lump or swelling can be the first sign of a benign tumor. However, the most common sign is persistent or increasing pain in the region of the tumor. Sometimes tumors are discovered only after a fracture occurs where the bone has been weakened by the growth of the tumor.

Pain associated with a bony lesion is cause for immediate concern.

What are my treatment options?

Medical Treatments

Treatment for benign bone tumors depends on the specific type of tumor, its size, its location, and age. Sometimes, surgery is not necessary. For example, some tumors will often resolve and heal after a fracture. Others may stop growing if the patient is near maturity at the time they are discovered. Some are discovered only by chance when an X-ray is taken for another reason such as an injury to a nearby area, and may only need to be observed for a period of time to insure that they are not growing or showing signs of being aggressive. Most often, however, surgery is necessary.

Surgical Treatments

Surgical treatment includes both removing the tumor and the regeneration of new healthy bone at the site of the tumor. The surgeon caring for these tumors must have knowledge and experience with specialized techniques for removing these tumors with minimal trauma to surrounding normal tissues. He or she must also have broad knowledge and experience with techniques for bone grafting and skeletal regeneration, in order to provide young patients with the greatest possible chance of returning to full and unlimited activities following successful treatment. Most benign tumors respond very well to surgical removal. The likelihood that the tumor will come back is low, usually less than 5%.

Some tumors, such as osteoid osteoma, are frequently treated by radio frequency ablation or thermal necrosis.  These procedures require anesthesia and are often done as a combined approach.  Patient evaluation is accomplished before the orthopaedic surgeon and radiologist examination.  

What are the risks of surgery?

Many times the surgery is very straightforward and includes a biopsy for the tissue to be studied under the microscope. Once confirmation is made of the diagnosis as a benign lesion, usually the lesion will be curetted (scraped out) and bone grafted.  It is unusual to have major problems with this type of surgery. However, risks include nerve injury, infection, bleeding, and stiffness.

How do I prepare for surgery?

  • Complete any pre-operative tests or lab work prescribed by your doctor.
  • Arrange to have someone drive you home from the hospital.
  • Refrain from taking aspirin and non-steroidal anti-inflammatory medications (NSAIDs) one week prior to surgery.
  • Call the appropriate surgery center to verify your appointment time.  If your surgery is being done at Cleveland Clinic, call 216.444.0281.
  • Refrain from eating or drinking anything after midnight the night before surgery.

Are there exercises I can start now prior to surgery?

Patients with lower extremity procedures most likely will require crutches.  Physical therapy, including crutch instruction, is easier to accomplish before the surgery.

What do I need to do the day of surgery?

  • If you currently take any medications, take them the day of your surgery with just a sip of water.
  • Do not wear any jewelry, body piercing, makeup, nail polish, hairpins or contacts. 
  • Leave valuables and money at home.
  • Wear loose-fitting, comfortable clothing.

What happens after surgery?

A post-operative instruction sheet will be provided.

How long is the recovery period after surgery?

The recovery period depends upon the bone lesion and location.  Wound healing takes about two weeks.  If bone healing is necessary, the physician may require patients to protect the extremity for six weeks from major forces such as full weight-bearing.

What is the rehab after surgery?

Depending on the procedure, physical therapy for crutch use, range-of-motion and strengthening may be required.

How can I manage at home during recovery from the procedure?

Instructions from the physician will be provided.  These will vary according to the procedure.


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This information is provided by Cleveland Clinic and is not intended to replace the medical advice of your doctor or health care provider. Please consult your health care provider for advice about a specific medical condition.

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