Department Cardiovascular Medicine
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English, Spanish
Surgeon No
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus

Specialties & Treatments

Treatment & Services

  • Abnormal Stress Test
  • Angiography
  • Angioplasty
  • Atherectomy
  • Cardiovascular Medicine
  • Cardiovascular Medicine Department
  • Clinical Trials
  • Coronary Artery Atherectomy
  • Coronary Balloon Angioplasty (PTCA)
  • Coronary Intervention
  • C-Reactive Protein Testing
  • Drug Eluting Stenting
  • FFR determination
  • General Cardiology
  • Intervention Section
  • Interventional Cardiology
  • Intra-aortic Balloon Pumping
  • Invasive & Interventional Cardiology Section
  • Invasive Cardiology
  • Invasive Cardiology Section
  • Pericardiocentesis
  • Rotational Atherectomy
  • Stress Testing
  • Virtual Histology
View all 24 Treatment & Services +

Specialty in Diseases & Conditions

  • Angina
  • Aortic Aneurysms
  • Bifurcation Blockage
  • Coronary Artery Disease
  • Heart Attack
  • Ischemic Cardiomyopathy
  • Restenosis
  • Stent Restenosis
View all 8 Specialties +


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About Conrad Simpfendorfer, MD

Conrad Simpfendorfer. MD, FACC, is an Interventional Cardiologist in the Robert and Suzanne Tomsich Department of Cardiovascular Medicine. He is board-certified in Internal Medicine, Cardiovascular Disease and Interventional Cardiology.

Specialty Interests: treatment of valvular heart disease and coronary artery disease. He specializes in cardiac catheterization and coronary interventions.

Success Rate: Cleveland Clinic has been ranked the #1 hospital for cardiology and heart surgery by U.S. News & World Report since 1994. Success rates for specific procedures are available at:

Education and Training:  A native of Chile, Dr. Simpfendorfer received his medical degree from Catholic University of Chile, in Santiago, graduating with "Unanimous Distinction." He completed his internship and residency in internal medicine at St. Luke's Hospital in Cleveland, followed by a fellowship in cardiology at Cleveland Clinic. He was appointed to Cleveland Clinic Staff in the Robert and Suzanne Tomsich Department of Cardiovascular Medicine in 1982.

Awards and Honors:  Dr. Simpfendorfer received the Distinguished Teacher Award from the Department of Cardiovascular Medicine in 1994 and from Interventional Cardiology in 2006 and 2016. In 2003, Dr. Simpfendorfer received the SOLACI Award from the Latin American Society of Interventional Cardiology for his continued support of educational activities of the Society. In 2006, he was honored by the Universidad Autonoma de Mexico with the Dr. Ignacio Chavez Medal. He was named among the Best Doctors in America for 2007 through 2013. In 2017, he was honored by Fundaliow Cardioinfantil, Colombia in support of education activities. In 2018 received the Cleveland Clinic Distinguished Alumus Award.

Research, Publications and Speaking: A frequent invited lecturer at international medical meetings, Dr. Simpfendorfer has authored more than one hundred articles and book chapters on his specialty interests. He has also served as the primary and co-investigator for numerous clinical studies related to coronary interventions.

Dr. Simpfendorfer is a Fellow of the American College of Cardiology (FACC), Fellow of the American Heart Association (FAHA), Fellow of the Society for Cardiac Angiography (FSCAI), Fellow of the American College of Angiology,  Fellow of the Interamerican College of Physicians and Surgeons. In addition, he is a member of the American College of Physicians and the International Andreas Gruentzig Society. He is an Honorary Member of the Cardiology Societies of Argentina, Chile, Ecuador and Peru.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Cleveland Clinic
Cardiovascular Diseases
Cleveland, OH USA

Fellowship - Cleveland Clinic
Cleveland, OH USA

Residency - Saint Luke's Medical Center
Internal Medicine
Cleveland, OH USA

Internship - Saint Luke's Medical Center
Internal Medicine
Cleveland, OH USA

Medical Education - Catholic University Medical School

Professional Highlights

  • Chairman of the Cleveland Clinic International Center from 1998 to 2006
  • Member of the Board of Governors and Board of Trustees from 2007-2010
  • Member of the International Leadership Board
  • Dr. Ignacio Chavez Medal, Universidad Autonoma de Mexico, 2006
  • Distinguished Teacher Award, Interventional Cardiology, 2006 and 2016
  • SOLACI Award, Latin American Society of Interventional Cardiology, 2003
  • Distinguished Teacher Award, Cardiovascular Medicine, 1994


  • Internal Medicine
  • Internal Medicine - Cardiovascular Disease

Specialty Interests

Coronary artery disease, stent restenosis, stent - coronary, cardiac catheterization, angioplasty, stent - coronary, coronary intervention

Awards & Honors

  • Best Doctors in America, 2007-2013 
  • Guest of Honor, City of Guayaquil, Ecuador, 2007
  • Dr. Ignacio Chavez Medal, Universidad Autonoma de Mexico, 2006
  • Distinguished Teacher Award, Section of Interventional Cardiology, Cleveland Clinic, 2005-2006
  • SOLACI Award, Latin American Society of Interventional Cardiology, 2003
  • Distinguished Teacher Award, Cardiovascular Medicine, Cleveland Clinic, 1994
  • Fundation Cardio-Infantil, Bogota, Colombia, 2017
  • Cleveland Clinic Distinguished Alumnus Award, 2018


  • American College of Cardiology
  • Society for Cardiac Angiography and Interventions
  • American College of Physicians
  • American Heart Association
  • Society of Cardiology of Argentina, Chile, Ecuador and Peru
Research & Publications

Research & Publications

See publications for Conrad Simpfendorfer, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 3/12/2020, Dr. Simpfendorfer has reported no financial relationship with industry that is applicable to this listing. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

147 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.9 out of 5
Explains 4.9
Listens 4.8
Courtesy, Respect & Concern 4.9
Patient Rating of Doctor 4.9

33 Patient Comments

Reviewed on Feb 6, 2020

I recommended Dr Zinfendorfer to a friend, who followed up and saw a cardiologist at the CC.

Reviewed on Dec 27, 2019

Everyone was very professional. Barely met Dr. Simpfendorfer, but the resident (Nicole) did a good job of explaining the procedure & answering questions. Dr. S. did spend time explaining the results with my wife & daughter while I was in recovery.

Reviewed on Dec 26, 2019

I have been working with Dr.Simpfendorfer For over 20 years he's kept me alive he's a great man very informative and I would recommend him 100%

Reviewed on Dec 19, 2019

Dr Simpfendorfer is one of the best doctors I have seen. He always carefully listens to my questions and takes the time to answer them. He always explains the risks associated with any procedure or medication and tells me what to look for. He is extremely personable and I have recommended him to several of my colleagues. His administrative assistant- Georgann Yonkers- is also top notch. The Cleveland Clinic is very lucky to have them.

Reviewed on Nov 22, 2019

only place that could help me, Dr Simpfendorfer is an excellent doctor, I wouldn't be here today without him

Reviewed on Nov 21, 2019

D r Simpendoffer is not only a best cardiologist, he is also a best physician and a care giver. He takes Time to listen to the complaint and takes a through history, take notes of the important parts. His physical examination is through for the cardiology. As retired surgeon I can say he is the only doctor I have seen to do a through examination and talk to the patient after the examination in his office, going over all the test results, and showing and explaining all the relevant tests displayed on the computer. I am fortunate to have him as my cardiologist in 1989 to diagnose my CAD and following me often since them following my CABAG. I have no complaint to report only to say that I can't praise him enough.

Reviewed on Oct 31, 2019

Everybody was very helpful and polite. My doctor is especially good at showing and explaining my medical exam results to me.

Reviewed on Oct 31, 2019

My doctor is exceptional in taking time to clearly explain everything about the medical tests that have been performed on me and also listens carefully to any questions that I have and responds to them very thoughtfully.

Reviewed on Oct 22, 2019

I Always receive Excellent comprehensive care from Dr. Simpfendorfer. Devotes needed time to review the findings and clearly explain any follow up appointments.

Reviewed on Sep 13, 2019

Not enough words to describe Dr. Simpfendorfer. Excellent physician, very caring and humble person. Always listens to your concerns and has time for his patients. Thank you for being the DOCTOR!

Reviewed on Sep 13, 2019

Dr. Simpfendorpher gives his undivided attention, explains, answers questions and treats me as if I were his only patient.

Reviewed on Sep 13, 2019

Dr. Simpfendorfer was very good and taking his time with me and explaining everything

Reviewed on Aug 22, 2019

Dr. S has a very kind, calming mannerism about him - you know he is highly educated and smart, is in charge of the visit, but is not intimidating nor does he have an ego to feed. those qualities are not something learned in school - a person is either born with it, acquire it from life experiences and/or he must have had a wonderful Mother

Reviewed on Aug 22, 2019

the Dr is very caring. gives me plenty of time

Reviewed on Jul 19, 2019

Georgeann is extremly helpfull as well as Clinican. efficiency thruout office. Dr.Simpfordenfer very pleasant, professional. Truly interested in my health. additional orders requested, so still active case. very happy so far with entire CCF EXPERIENCE!!

Reviewed on Jul 19, 2019

Dr Simpfendorfer is a wonderful physician and person.

Reviewed on Jul 18, 2019

Dr. Conrad Simphendorfer, in my experience and again proved by this recent visit, is the most caring Doctor I have ever come across. He takes the time to care for you no matter what the Cleveland Clinic guidelines are for moving the doctors quickly through the patients they have, in order to bolster the Cleveland Clinic bottom line.

Reviewed on Jul 18, 2019

Dr S is excellent.I appreciate his care and positive attitude.

Reviewed on Jul 11, 2019

*Dr. Simpfendorfer is an excellent dr.

Reviewed on Jul 5, 2019

Dr. Simpfendorfer is a caring and thorough care provider.

Reviewed on Jun 7, 2019

Georgann Yonkers has always been able to get me in to see Dr. Simpfendorfer as quickly as possible. She always responds to my phone messages and emails.

Reviewed on Jun 7, 2019

Dr. Simpfendorfer is one of the best doctors that I have ever seen. He always listens to all of my concerns and symptoms and addressed each one on a scientific and professional level. I am very grateful to have been a patient of Dr. Simpfendorfer as he saved my life back in 2017. I will continue to recommend him to all of my colleagues and friends. He has excellent bedside manner and is easy to talk to. You can tell that he cares about each and every patient.

Reviewed on Jun 7, 2019

Dr. Simpfendorfer is not only one of the best doctors at the clinic but is a good man. He takes time to discuss all concerns and makes you fill at ease. I am fortunate that he is my cardiologist.

Reviewed on May 16, 2019

Dr. Simphendorfer has been my cardiologist for most of my 38 years with Cleveland Clinic. Dr. Simphendorfer took over for Dr. Mason Sones who was my originalcardiologist. Dr. Simphendorfer has been there there for myself and my needs no matter where I have been in my life and it has been a blessing.

Reviewed on May 10, 2019

DR S the BEST!

Reviewed on May 10, 2019

*Dr. Simpfendorfer is all one could hope for in a cardiologist.

Reviewed on May 9, 2019

Excellent service and attention to the problem/concerns of the patient. Dr Simpfendorfer instills confidence and a personal touch that is not the norm with many current doctors and health facilities. I dont enjoy the 6 hour drive to Cleveland, but knowing that the attention to my health from everyone, off-sets the inconvenience of getting to the CC.

Reviewed on Apr 26, 2019

Dr Simpfendorfer has always been personable but straight forward and willing to answer any questions or concerns I have had regarding my heart issues.

Reviewed on Apr 25, 2019

This doctor is pleasant, listens well and shows much patience. Excellent and professional.

Reviewed on Mar 19, 2019

Dr. Simpfendorfer's organization and efficiency beyond compare. I would have no other cardiologist.

Reviewed on Mar 19, 2019

Dr. Simpfendorfer has earned my complete trust with his calm demeanor and skilled orchestration of the activities during my cardiac procedure.

Reviewed on Feb 26, 2019

he is the best doctor I have ever seen. he is vary concerned about my health.

Reviewed on Feb 7, 2019

There simply are no words to express our gratitude for the care we received from Dr. Simpfendorfer. We were treated as if we were the only person in the world. Completely given kindness, respect and full understanding of tests done and explanation of condition and treatment. Dr Simpfendorfer's staff stayed late to assist us and it was all done with smiles, kindness and respect. We are truly grateful.

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