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Department Cardiovascular Medicine
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English, Spanish
Surgeon No
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus

Specialties & Treatments

Treatment & Services

  • Abnormal Stress Test
  • Angiography
  • Angioplasty
  • Atherectomy
  • Cardiovascular Medicine
  • Cardiovascular Medicine Department
  • Clinical Trials
  • Coronary Artery Atherectomy
  • Coronary Balloon Angioplasty (PTCA)
  • Coronary Intervention
  • C-Reactive Protein Testing
  • Drug Eluting Stenting
  • FFR determination
  • General Cardiology
  • Intervention Section
  • Interventional Cardiology
  • Intra-aortic Balloon Pumping
  • Invasive & Interventional Cardiology Section
  • Invasive Cardiology
  • Invasive Cardiology Section
  • Pericardiocentesis
  • Rotational Atherectomy
  • Stress Testing
  • Virtual Histology
View all 24 Treatment & Services +

Specialty in Diseases & Conditions

  • Angina
  • Aortic Aneurysms
  • Bifurcation Blockage
  • Coronary Artery Disease
  • Heart Attack
  • Ischemic Cardiomyopathy
  • Restenosis
  • Stent Restenosis
View all 8 Specialties +


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About Conrad Simpfendorfer, MD

Conrad Simpfendorfer. MD, FACC, is an Interventional Cardiologist in the Robert and Suzanne Tomsich Department of Cardiovascular Medicine. He is board-certified in Internal Medicine, Cardiovascular Disease and Interventional Cardiology.

Specialty Interests: treatment of valvular heart disease and coronary artery disease. He specializes in cardiac catheterization and coronary interventions.

Success Rate: Cleveland Clinic has been ranked the #1 hospital for cardiology and heart surgery by U.S. News & World Report since 1994. Success rates for specific procedures are available at:

Education and Training:  A native of Chile, Dr. Simpfendorfer received his medical degree from Catholic University of Chile, in Santiago, graduating with "Unanimous Distinction." He completed his internship and residency in internal medicine at St. Luke's Hospital in Cleveland, followed by a fellowship in cardiology at Cleveland Clinic. He was appointed to Cleveland Clinic Staff in the Robert and Suzanne Tomsich Department of Cardiovascular Medicine in 1982.

Awards and Honors:  Dr. Simpfendorfer received the Distinguished Teacher Award from the Department of Cardiovascular Medicine in 1994 and from Interventional Cardiology in 2006 and 2016. In 2003, Dr. Simpfendorfer received the SOLACI Award from the Latin American Society of Interventional Cardiology for his continued support of educational activities of the Society. In 2006, he was honored by the Universidad Autonoma de Mexico with the Dr. Ignacio Chavez Medal. He was named among the Best Doctors in America for 2007 through 2013. In 2017, he was honored by Fundaliow Cardioinfantil, Colombia in support of education activities. In 2018 received the Cleveland Clinic Distinguished Alumus Award.

Research, Publications and Speaking: A frequent invited lecturer at international medical meetings, Dr. Simpfendorfer has authored more than one hundred articles and book chapters on his specialty interests. He has also served as the primary and co-investigator for numerous clinical studies related to coronary interventions.

Dr. Simpfendorfer is a Fellow of the American College of Cardiology (FACC), Fellow of the American Heart Association (FAHA), Fellow of the Society for Cardiac Angiography (FSCAI), Fellow of the American College of Angiology,  Fellow of the Interamerican College of Physicians and Surgeons. In addition, he is a member of the American College of Physicians and the International Andreas Gruentzig Society. He is an Honorary Member of the Cardiology Societies of Argentina, Chile, Ecuador and Peru.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Cleveland Clinic
Cardiovascular Diseases
Cleveland, OH USA

Residency - Cleveland Clinic
Internal Medicine
Cleveland, OH USA

Residency - Saint Luke's Medical Center
Internal Medicine
Cleveland, OH USA

Internship - Saint Luke's Medical Center
Internal Medicine
Cleveland, OH USA

Medical Education - Catholic University Medical School

Professional Highlights

  • Chairman of the Cleveland Clinic International Center from 1998 to 2006
  • Member of the Board of Governors and Board of Trustees from 2007-2010
  • Member of the International Leadership Board
  • Dr. Ignacio Chavez Medal, Universidad Autonoma de Mexico, 2006
  • Distinguished Teacher Award, Interventional Cardiology, 2006 and 2016
  • SOLACI Award, Latin American Society of Interventional Cardiology, 2003
  • Distinguished Teacher Award, Cardiovascular Medicine, 1994


  • Internal Medicine
  • Internal Medicine - Cardiovascular Disease

Specialty Interests

Coronary artery disease, stent restenosis, stent - coronary, cardiac catheterization, angioplasty, stent - coronary, coronary intervention

Awards & Honors

  • Best Doctors in America, 2007-2013 
  • Guest of Honor, City of Guayaquil, Ecuador, 2007
  • Dr. Ignacio Chavez Medal, Universidad Autonoma de Mexico, 2006
  • Distinguished Teacher Award, Section of Interventional Cardiology, Cleveland Clinic, 2005-2006
  • SOLACI Award, Latin American Society of Interventional Cardiology, 2003
  • Distinguished Teacher Award, Cardiovascular Medicine, Cleveland Clinic, 1994
  • Fundation Cardio-Infantil, Bogota, Colombia, 2017
  • Cleveland Clinic Distinguished Alumnus Award, 2018


  • American College of Cardiology
  • Society for Cardiac Angiography and Interventions
  • American College of Physicians
  • American Heart Association
  • Society of Cardiology of Argentina, Chile, Ecuador and Peru
Research & Publications

Research & Publications

See publications for Conrad Simpfendorfer, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 7/2/2020, Dr. Simpfendorfer has reported no financial relationship with industry that is applicable to this listing. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

142 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
5 out of 5
Explains 5
Listens 5
Courtesy, Respect & Concern 5
Patient Rating of Doctor 5

36 Patient Comments

Reviewed on Sep 15, 2021

Dr. Simpfendorfer is a great doctor and very well know as being one of the best. I actually quit going to another cardiologist closer to me to go to him.

Reviewed on Aug 18, 2021

I appreciate Dr. Simpendorfer as he identifies an issue and discusses with me how to improve the issue. Dr. S is very attentive to my needs and concerns.

Reviewed on Aug 17, 2021

Dr Simpfendorfer is very pleasant and thorough. He listens to all questions and never makes you feel rush. I plan to keep seeing him as a patient.

Reviewed on Aug 10, 2021

Dr Simpfendorfer explained everthing very clearly,and we felt very comfortable with is manner and experience

Reviewed on Aug 10, 2021

Will be returning again to see Dr.Simpfendorfer

Reviewed on Aug 10, 2021

Dr. Simpfendorfer's concern and advice for the entire health situation, not just the initial reason for my visit, was exemplary and extremely valuable. Followup actions for a modified analysis and treatment plan were immediate and greatly appreciated.

Reviewed on Jul 14, 2021

Best Dr Ever! I wish every Dr was as awesome as Dr Simpendorfer

Reviewed on Jul 14, 2021

Dr Simpendorfer's extensive knowledge of my very rare condition was awesome and such a relief to finally have someone who could help me.

Reviewed on Jul 14, 2021

Dr Simpendorfer is such a great Dr. I am grateful we could connect and he helped me so much.

Reviewed on Jul 7, 2021

Dr. Simpfendorfer listened to my concerns and spent time explaining things to me. He even showed me how his smart watch can take an EKG.

Reviewed on Jul 7, 2021

Excellent, I love Dr Simfendorfer, he is really a great doctor and very personable guy. Just a wonderful person to be around, I'm sure!!!

Reviewed on Jun 30, 2021

Doctor Simpfendorfer always takes as much time as needed to go over everything and explain & answer questions I have no matter how far behind he is. He is an excellent doctor and I have great respect for him.

Reviewed on Jun 30, 2021

Dr. Simpendorfer is an amazing doctor. He listens to all of my questions, addresses all of my concerns, goes thru all of my studies making sure I understand all that is being presented. He is the best doctor who has ever cared for me.

Reviewed on Jun 30, 2021

Did not like that I didn't meet attending dr performing cath and stent until I was on table and never again. The dr/ fellow who did stents provided Different information and discharge instructions with me than the information that was shared by the Attending Physician with me and my family so very confusing. Also he lacked bedside manner and his tone with nurses was sometimes inappropriate. Just hope his lack of ppl skills means he had excellent technical skills but having more angina post procedure so have concerns

Reviewed on Jun 29, 2021

Best care with personal touch from a doctor I ever had.

Reviewed on Jun 29, 2021

Dr. Conrad Simpfendorfer has been an excellent provider for my husband for over 25 years and myself for 9.

Reviewed on Jun 9, 2021

I was truly amazed how everything went so smoothly. itinerary that was sent to me was on time and staff was very professional. dr singe forget was pleasant, professional and explained everything in clear simple terms. I have nothing bad to say regarding my visit. I will be back in July for follow up treatment .

Reviewed on Jun 9, 2021

Dr. secretary is very efficient and friendly

Reviewed on Jun 9, 2021

Dr Simpendorfer is a wonderful person and an excellent physician

Reviewed on May 25, 2021

Dedicated, patient, carrying provider.

Reviewed on May 13, 2021

Dr Simpfendorfer was fantastic. He took time to understand my issue and concerns. He spent plenty of time with me. i never felt rushed. most importantly he provided answers and his opinion on next steps for my care. He explained everything in a manner that was easily understood. I was very impressed by the doctor and feel good about my decision to come to Cleveland Clinic for a second opinion.

Reviewed on Apr 27, 2021

Dr. Simpfendorfer is the absolute BEST!

Reviewed on Apr 27, 2021

Dr. Simpendoffer communicates with me with courtesy, respect and with excellent manner about my condition. As a cardiologist his examination is through compared to others I have seen.

Reviewed on Apr 21, 2021

My care was provided by Dr. , Who I went to see.

Reviewed on Apr 15, 2021

Dr. Simpfendrfer is a model for all MD's none like him in communication, diagnosis, direct concern, explanations, Directives

Reviewed on Apr 15, 2021

Dr. Simpfendrfer is a model for all MD's none like him in communication, diagnosis, direct concern, explanations, Directives . A true preventive cardiologist

Reviewed on Apr 13, 2021

Very professional, courteous, friendly and very friendly. Highly recommended Cleveland Clinic,Dr. Simfordofer and his staff. Plus the Lab, EKG and Echo were very professional and nice.

Reviewed on Feb 26, 2021

Dr. Simpfendorfer is the finest doctor CCF has on staff

Reviewed on Feb 12, 2021

Dr. Simpfendorfer is pure class- very professional

Reviewed on Feb 4, 2021

Wonderful experience, as always. Dr. Simpenfendorfer is THE best doctor! He is so compassionate and caring. He has the best bedside manner we have ever encountered. He has a wonderful personality. If only all doctors could come from his mold!! He is so knowledgeable and I am so glad to have the privilege to be his patient. I have all the faith in the world in him. Such a wonderful person!

Reviewed on Feb 4, 2021

Everyone we have ever encountered in our annual visits has been very cordial, caring and compassionate. They make you feel like you really matter and are not just a number. Dr. Simpfendorfer is THE best doctor! If only all doctors could come from his mold! He is the most compassionate, caring, friendly, and knowledgeable doctor we have ever had in our 71 years! If only we could have him as our doctor for everything!

Reviewed on Jan 28, 2021

As always, Doctor Simpfendorfer is outstanding in his field and is a pleasure to see regarding my heart condition.

Reviewed on Dec 10, 2020

everyone was the epitome of competence and dr simpfendorfer made me feel relaxed and that everything was under control clinic is the best period!!!

Reviewed on Dec 3, 2020

Dr.'s office staff are always very easy to work with & they are always accommodating.

Reviewed on Nov 20, 2020

It has always been a pleasant experience to discuss my health issues with DR. Simpfendorfer. He listens to my concerns and answers my questions. Which brings me to a level of confidence on my treatment course.

Reviewed on Nov 19, 2020

Dr. Simpfendorfer was outstanding as usual.

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