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Title Section Head, Pediatric Epilepsy
Department Epilepsy Center
Primary Location Cleveland Clinic Main Campus
Type of Doctor Children & Adolescents Only
Languages English, Hindi
Surgeon No
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus

Specialties & Treatments

Treatment & Services

  • Center for Pediatric Epilepsy
  • Cortical Brain Mapping
  • Early Epilepsy Surgery
  • Epilepsy Pharmacotherapy with Call Office
  • Epilepsy Surgery
  • Epilepsy Surgery And Video Eeg Evaluation
  • Epilepsy Surgery Evaluation
  • Epilepsy Surgery in Adolescents
  • Epilepsy Surgery In Children
  • Evoked Potential Tests
  • Intraoperative Brain Mapping And Monitoring
  • Intra-operative Brain Mapping for Epilepsy Surgery
  • Magnetoencephalography (meg)
  • Neuroimaging (mri, Pet, Spect, Meg Scans)
  • Pediatric Neuroscience
  • Signal Analyses of Subdural Recordings
  • Specialized EEG With Subdural Grids
  • Surgery In Brain Malformations
  • Vagal Nerve Stimulation
  • Video EEG Monitoring
View all 20 Treatment & Services +

Specialty in Diseases & Conditions

  • Autoimmune Epilepsy
  • Benign Focal Epilepsies and Variants
  • Brain Malformations Causing Epilepsy
  • Clinical Neurophysiology
  • Developmental Disorders Of The Brain
  • Dravet and Doose Syndrome and other Myoclonic Epilepsies
  • Electroencephalogram (EEG)
  • Epilepsy
  • Epilepsy in Children
  • First Seizure Assessment
  • Infantile Spasm
  • Ketogenic Diet
  • Lennox-Gastaut Syndrome
  • Lissencephaly
  • Malformations Of Cortical Development
  • Non-epileptic seizure disorder
  • Rasmussen Encephalitis
  • Seizure Manifestations
  • Seizures
  • Seizures - Febrile
  • Sleep and Epilepsy Issues
  • Status Epilepticus (continuous Seizures)
  • Sturge-Weber Syndrome
  • Tuberous Sclerosis Complex
View all 24 Specialties +


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About Ajay Gupta, MD

Ajay Gupta, M.D. is the head of the section of Pediatric Epilepsy in the Epilepsy Center/Neurological Institute. He is Professorat The Cleveland Clinic Lerner College of Medicine, Case Western Reserve University. He is also the founder director of multidisciplinary Tuberous Sclerosis Program at the Cleveland Clinic.

Dr. Gupta is an expert in the field of childhood and adolescent epilepsy with emphasis on epilepsy surgery evaluation,management of complex childhood epilepsies, and neurocutaneous disorders such as Tuberous Sclerosis Complex and Sturge-Weber syndrome.  Dr. Gupta is also a skilled specialist in intra-operative neurophysiological techniques used during brain surgery to map regions of brain for critical function. His expertise attracts national and international consultations from families and practicing Neurologists who seek a second opinion for complex cases. Dr. Gupta is recognized by the Consumers' Research Council's 'Top Physicians' ofAmerica", Marquis’ "Who's Who in America", and the “Best Doctors in America”.

Dr. Gupta serves on the professional and scientific committees of the American Epilepsy Society, Child Neurology Society, and International League against Epilepsy. He serves on the editorial board of prestigious journals in the field, ‘Pediatric Neurology’ and Epilepsy Currents’. Dr. Gupta also works on the Professional and Scientific Board of the U.S. Tuberous Sclerosis Alliance. He serves on the peer-review panel of national and international journals in the field of epilepsy. He is a fellowmember of the American Academy of Neurology, American Epilepsy Society, Child Neurology Society, International Child Neurology Association, and American Academy of Pediatrics.

Dr. Gupta has made innovative and pioneering contributions to advance the field of epilepsy surgery and treatment of epilepsy in children. A unique disease is named after him as a co-discoverer ("> His research interests are epilepsy surgery evaluation tools and outcomes, Tuberous Sclerosis Complex, and impact of epilepsy on brain development. He has authored over 150 original research articles, review papers in the peer-reviewed international journals, as well as textbooks. He is an avid mentor of residentand fellow trainees including visiting international fellows and junior faculty. Some of the trainees have received highly competitive awards and honors for their mentored research projects such as the Junior Investigator Research Awards at the American Epilepsy Society and Child Neurology Society, and Thomas Epilepsy award at the Cleveland Clinic Neuroscience Research competition. Many traineescurrently hold faculty positions at prestigious universities and hospitals in US and abroad. Dr. Gupta has also organized, chaired and directed many symposia, workshops, and seminars at the scientific national and international conferences. He is the Director of the annual Epilepsy Course organized at the Cleveland Clinic. He is an invited faculty to many national and international meetings to deliver lectures, workshops and skills training.

Dr. Gupta is board certified in the specialties of Pediatrics, Neurology/Child Neurology, EEG/Clinical Neurophysiology, and Epilepsy.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Cleveland Clinic
Clinical Neurophysiology, EEG & Epilepsy
Cleveland, OH USA

Fellowship - Cleveland Clinic Epilepsy Training Program
Clinical Neurophysiology
Cleveland, OH USA

Residency - Cleveland Clinic
Cleveland, OH USA

Fellowship - Saint George's Hospital Medical School, University of London
Clinical Genetics - Research

Medical Education - Post Graduate Institute of Medical Education and Research
Chandigarh, India

Medical Education - Punjab University Faculty of Medicine

Medical Education - Guru Nanak Dev University Faculty of Medicine

Undergraduate - Punjab University/DAV College

Medical Education - Government Medical Institute Patiala

Internship - Institute of Medical Education and Research

Professional Highlights

  • Head, Section of Pediatric Epilepsy, Cleveland Clinic
  • Professor, Cleveland Clinic Lerner College of Medicine of the Case Western Reserve University
  • Editorial Boards: Pediatric Neurology (current), Epileptic Disorders (past)
  • Contributing editor: Epilepsy Currents, contributing editor
  • Tuberous Sclerosis Alliance: Professional and Scientific Board
  • American Epilepsy Society: multiple professional and scientific committees
  • Child Neurology Society: multiple professional and scientific committee


  • Psychiatry and Neurology - Neurology with Special Qualifications in Child Neurology
  • Psychiatry and Neurology - Clinical Neurophysiology
  • Psychiatry and Neurology - Epilepsy

Specialty Interests

Surgical and medical treatment of children with epilepsy, epilepsy treatment in neurocutaneous disorders like tuberous sclerosis complex and sturge weber syndrome, intra-operative monitoring and brain mapping for epilepsy surgery

Awards & Honors

  • Kiffin Penry Pediatric Epilepsy award
  • Elected Fellow, American Academy of Pediatrics
  • Judge, Neuroscience Research, Cleveland Clinic
  • Marquis “Who’s Who in America”
  • “Top Physicians of America”, Consumers’ Research Council of America, Washington, DC
    Best Doctors in America
  • America’s Top Pediatricians, Consumers Research Council of America
  • Cleveland Clinic Caregiver Appreciation Award, Core value: service
  • Fellow, American Epilepsy Society
  • Judge, Research Awards, Association of Child Neurology Meeting, New Delhi, India
  • Top Doctors of America (Castle Connolly)


  • American Epilepsy Society
  • American Academy of Neurology
  • Child Neurology Society (USA)
  • American Academy of Pediatrics
  • International Child Neurology Association
Research & Publications

Research & Publications

See publications for Ajay Gupta, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 8/16/2021, Dr. Gupta has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Consulting and/or Speaking. Dr. Gupta receives fees of $5,000 or more per year as a paid consultant, speaker or member of an advisory committee for the following companies:

  • Eisai Co., Ltd.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

73 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.7 out of 5
Explains 4.7
Listens 4.5
Courtesy, Respect & Concern 4.7
Time Spent with Patient 4.5
Patient Rating of Doctor 4.8

12 Patient Comments

Reviewed on Aug 26, 2021

Experience was excellent with the provider

Reviewed on Aug 5, 2021

Doctor Gupta is a wonderful caring doctor

Reviewed on Jul 20, 2021

We've always felt like we are being heard with Dr Gupta. He's an excellent doctor that makes you feel comfortable and takes his time without rushing. He truly listens to your thoughts and concerns.

Reviewed on Jul 8, 2021

Dr Gupta's intuition knew something was wrong when we went in on a Thursday. Friday he got us into the emergency Pediatric epilepsy floor, by Saturday morning it was confirmed that what our son is experiencing is seizures. Dr Gupta and his team are working to save his quality of life and we are forever grateful

Reviewed on Jun 21, 2021

I was impressed with how seriously Dr Gupta and the Cleveland Clinic took Rileys case. Riley was treated as a high priority case and was given an appointment and admission very quickly.

Reviewed on May 19, 2021

I have been coming here for years and it has always been great my doctor has helped me so much

Reviewed on Mar 16, 2021

Dr. Gupta is an excellent doctor. He listens to my concerns and explains things thoroughly.

Reviewed on Feb 18, 2021

Dr. Gupta is a great listener and epileptologist. he is very well informed about my child when I bring him in and don't have to start over in regards to why we are there to see him.

Reviewed on Dec 23, 2020

dr gupta is a very caring physician and person , who is extremely supportive

Reviewed on Dec 22, 2020

Dr.Gupta is a great neurologist. I know a couple of people that has him for a neurologist. we see him every 6 months and if I have a question paula his nurse always tries to find the answer.

Reviewed on Dec 15, 2020

With a 5 hour drive, COVID exposure risks, and limited resources in our home town, we are very grateful to Cleveland Clinic and Dr. Gupta for providing this service.

Reviewed on Nov 25, 2020

Excellent provider, extremely knowledgeable, polite and courteous demeanor. Able to explain complexities with simple and easy to understand language.

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