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Title Section Head, Pediatric Epilepsy
Department Epilepsy Center
Primary Location Cleveland Clinic Main Campus
Type of Doctor Children & Adolescents Only
Languages English, Hindi
Surgeon No
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus


Additional Locations

Specialties & Treatments

Treatment & Services

  • Brain Malformation Surgery
  • Center for Pediatric Epilepsy
  • Clinical Neurophysiology
  • Cortical Brain Mapping
  • Epilepsy Pharmacotherapy with Call Office
  • Epilepsy Surgery
  • Epilepsy Surgery and Video EEG Evaluation
  • Epilepsy Surgery Evaluation
  • Epilepsy Surgery in Children
  • Evoked Potential Tests
  • First Seizure Assessment
  • Intraoperative Brain Mapping and Monitoring
  • Intraoperative Brain Mapping for Epilepsy Surgery
  • Magnetoencephalography (MEG)
  • Neuroimaging (MRI, PET, SPECT, MEG Scans)
  • Pediatric Neuroscience
  • Specialized EEG with Subdural Grids
  • Subdural Recording Signal Analysis
  • Vagal Nerve Stimulation
  • Video EEG Monitoring
View all 20 Treatment & Services +

Specialty in Diseases & Conditions

  • Autoimmune Epilepsy
  • Benign Focal Epilepsies and Variants
  • Brain Malformations Causing Epilepsy
  • Developmental Disorders of the Brain
  • Doose Syndrome
  • Dravet Syndrome
  • Epilepsy
  • Infantile Spasm
  • Ketogenic Diet
  • Lennox-Gastaut Syndrome
  • Lissencephaly
  • Malformations of Cortical Development
  • Myoclonic Epilepsy
  • Non-Epileptic Seizure
  • Pediatric Epilepsy
  • Rasmussen Encephalitis
  • Seizures
  • Seizures - Febrile
  • Sleep and Epilepsy Issues
  • Status Epilepticus (Continuous Seizures)
  • Sturge-Weber Syndrome
  • Tuberous Sclerosis Complex
View all 22 Specialties +


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About Ajay Gupta, MD

Ajay Gupta, M.D. is the head of the section of Pediatric Epilepsy in the Epilepsy Center/Neurological Institute. He is Professorat The Cleveland Clinic Lerner College of Medicine, Case Western Reserve University. He is also the founder director of multidisciplinary Tuberous Sclerosis Program at the Cleveland Clinic.

Dr. Gupta is an expert in the field of childhood and adolescent epilepsy with emphasis on epilepsy surgery evaluation,management of complex childhood epilepsies, and neurocutaneous disorders such as Tuberous Sclerosis Complex and Sturge-Weber syndrome.  Dr. Gupta is also a skilled specialist in intra-operative neurophysiological techniques used during brain surgery to map regions of brain for critical function. His expertise attracts national and international consultations from families and practicing Neurologists who seek a second opinion for complex cases. Dr. Gupta is recognized by the Consumers' Research Council's 'Top Physicians' ofAmerica", Marquis’ "Who's Who in America", and the “Best Doctors in America”.

Dr. Gupta serves on the professional and scientific committees of the American Epilepsy Society, Child Neurology Society, and International League against Epilepsy. He serves on the editorial board of prestigious journals in the field, ‘Pediatric Neurology’ and Epilepsy Currents’. Dr. Gupta also works on the Professional and Scientific Board of the U.S. Tuberous Sclerosis Alliance. He serves on the peer-review panel of national and international journals in the field of epilepsy. He is a fellowmember of the American Academy of Neurology, American Epilepsy Society, Child Neurology Society, International Child Neurology Association, and American Academy of Pediatrics.

Dr. Gupta has made innovative and pioneering contributions to advance the field of epilepsy surgery and treatment of epilepsy in children. A unique disease is named after him as a co-discoverer. His research interests are epilepsy surgery evaluation tools and outcomes, Tuberous Sclerosis Complex, and impact of epilepsy on brain development. He has authored over 150 original research articles, review papers in the peer-reviewed international journals, as well as textbooks. He is an avid mentor of residentand fellow trainees including visiting international fellows and junior faculty. Some of the trainees have received highly competitive awards and honors for their mentored research projects such as the Junior Investigator Research Awards at the American Epilepsy Society and Child Neurology Society, and Thomas Epilepsy award at the Cleveland Clinic Neuroscience Research competition. Many traineescurrently hold faculty positions at prestigious universities and hospitals in US and abroad. Dr. Gupta has also organized, chaired and directed many symposia, workshops, and seminars at the scientific national and international conferences. He is the Director of the annual Epilepsy Course organized at the Cleveland Clinic. He is an invited faculty to many national and international meetings to deliver lectures, workshops and skills training.

Dr. Gupta is board certified in the specialties of Pediatrics, Neurology/Child Neurology, EEG/Clinical Neurophysiology, and Epilepsy.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Cleveland Clinic
Clinical Neurophysiology, EEG & Epilepsy
Cleveland, OH USA

Residency - Cleveland Clinic
Cleveland, OH USA

Fellowship - Saint George's Hospital Medical School, University of London
Clinical Genetics - Research

Medical Education - Post Graduate Institute of Medical Education and Research
Chandigarh, India

Medical Education - Punjab University Faculty of Medicine

Medical Education - Guru Nanak Dev University Faculty of Medicine

Undergraduate - Punjab University/DAV College
Chandigarh, India

Professional Highlights

  • Head, Section of Pediatric Epilepsy, Cleveland Clinic
  • Professor, Cleveland Clinic Lerner College of Medicine of the Case Western Reserve University
  • Editorial Boards: Pediatric Neurology (current), Epileptic Disorders (past)
  • Contributing editor: Epilepsy Currents, contributing editor
  • Tuberous Sclerosis Alliance: Professional and Scientific Board
  • American Epilepsy Society: multiple professional and scientific committees
  • Child Neurology Society: multiple professional and scientific committee


  • Psychiatry and Neurology - Epilepsy
  • Psychiatry and Neurology - Neurology with Special Qualifications in Child Neurology
  • Psychiatry and Neurology - Clinical Neurophysiology

Specialty Interests

Surgical and medical treatment of children with epilepsy, epilepsy treatment in neurocutaneous disorders like tuberous sclerosis complex and sturge weber syndrome, intra-operative monitoring and brain mapping for epilepsy surgery

Awards & Honors

  • Kiffin Penry Pediatric Epilepsy award
  • Elected Fellow, American Academy of Pediatrics
  • Judge, Neuroscience Research, Cleveland Clinic
  • Marquis “Who’s Who in America”
  • “Top Physicians of America”, Consumers’ Research Council of America, Washington, DC
    Best Doctors in America
  • America’s Top Pediatricians, Consumers Research Council of America
  • Cleveland Clinic Caregiver Appreciation Award, Core value: service
  • Fellow, American Epilepsy Society
  • Judge, Research Awards, Association of Child Neurology Meeting, New Delhi, India
  • Top Doctors of America (Castle Connolly)


  • American Epilepsy Society
  • American Academy of Neurology
  • Child Neurology Society (USA)
  • American Academy of Pediatrics
  • International Child Neurology Association
Research & Publications

Research & Publications

See publications for Ajay Gupta, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 12/29/2023, Dr. Gupta has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Consulting and/or Speaking. Dr. Gupta receives fees of $5,000 or more per year (or, in rare cases, equity or stock options) as a paid consultant, speaker or as a member of an advisory committee for the following companies:

  • Catalyst Pharmaceuticals
  • Jazz Pharmaceuticals, plc
  • UCB Pharmaceuticals, Inc.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

86 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.8 out of 5
Explains 4.8
Listens 4.3
Courtesy, Respect & Concern 4.8
Time Spent with Patient 4.3
Patient Rating of Doctor 4.9

12 Patient Comments

Reviewed on Mar 27, 2024

The fellow took a thorough background on my son, asked follow up questions, and genuinely sought to understand his current condition and history. Then, the fellow briefed Dr. Gupta and both returned to the visit aligned on next steps and discussed those with me.

Reviewed on Feb 19, 2024

Dr Gupta is very receptive to our input

Reviewed on Feb 8, 2024

We couldn't be happier with our change in care to Dr. Gupta.

Reviewed on Jan 22, 2024

We appreciated Dr. Gupta's patience and clear explanations of our daughter's condition and possible treatments

Reviewed on Jan 4, 2024

Dr. Gupta has consistently demonstrated outstanding qualities, notably his ability to be a keen listener. His compassionate approach and unwavering commitment to putting the patient's needs first are truly commendable. His dedication and ethical approach to his craft not only inspire confidence but also deeply reflect his professional integrity.

Reviewed on Dec 14, 2023

Wonderful and empathetic ! Dr. Gupta and his team look at all aspects based on risk-benefits approach; coming up with treatment plan for the patient and his family.

Reviewed on Oct 17, 2023

Dr AJay Gupta was very through with our daughter. He answered any questions we had and made sure we understood every answer he gave us!! He took his time and spent all the time we needed him for

Reviewed on Oct 16, 2023

We already have recommended him to a few different people.

Reviewed on Oct 9, 2023

Dr. Gupta is the best!

Reviewed on Jul 19, 2023

*Dr. Gupta is an amazing doctor.

Reviewed on Jun 14, 2023

I love Dr Gupta. He takes his time and explains everything

Reviewed on Jun 6, 2023

I will certainly recommend Cleveland Clinic to anyone over and over again. Doctors answered my questions clearly and in simple ways for me to understand. They provided a clear diagnosis and a treatment plan going forward. I left the hospital more hopeful than I came.

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