Department Hematology and Medical Oncology
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English
Surgeon No
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus


Additional Locations

Specialties & Treatments

Treatment & Services

  • Bone Marrow Transplantation
  • Hematopoietic Stem Cell Transplantation
View all 2 Treatment & Services +

Specialty in Diseases & Conditions

  • Leukemia
View all 1 Specialties +


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About Matt Kalaycio, MD

Matt Kalaycio, MD, FACP, is the former Chairman of the Department of Hematology and Medical Oncology at Cleveland Clinic Taussig Cancer Institute. Dr. Kalaycio is also a Professor in the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University. Board-certified in hematology, Dr. Kalaycio's clinical interests are in leukemia and hematopoietic cell transplantation.

Dr. Kalaycio has published over 200 articles in numerous scientific publications including Bone Marrow Transplantation, Journal of Clinical Oncology, and Leukemia. He serves on the editorial board of Biology of Blood and Marrow Transplantation.  He also is the editor of a book on leukemia and co-editor of a book on clinical malignant hematology. He is the former Editor-in Chief of Hematology News.  He sits on the Board of Directors for the National Comprehensive Cancer Network (NCCN).

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Cleveland Clinic
Cleveland, OH USA

Fellowship - Cleveland Clinic
Medical Oncology
Cleveland, OH USA

Residency - UPMC Mercy Hospital of Pittsburgh
Internal Medicine
Pittsburgh, PA USA

Internship - UPMC Mercy Hospital of Pittsburgh
Medical Internship
Pittsburgh, PA USA

Medical Education - West Virginia University School of Medicine
Morgantown, WV USA

Undergraduate - Cornell University
Ithaca, NY USA


  • Internal Medicine - Hematology

Specialty Interests

Bone marrow transplantation, leukemia, myeloma, cancer, chronic lymphocytic leukemia, chronic myelogenous leukemia, hairy cell leukemia, leukemia

Awards & Honors

  • Castle Connelly's "America's Top Doctors"
  • Best Doctors' "Best Doctors in America"
  • Fellow, American College of Physicians
Research & Publications

Research & Publications

See publications for Matt Kalaycio, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 2/13/2019, Dr. Kalaycio has reported no financial relationship with industry that is applicable to this listing. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

117 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.9 out of 5
Explains 4.9
Listens 5
Courtesy, Respect & Concern 4.9
Knows Medical History 5
Time Spent with Patient 4.9
Patient Rating of Doctor 4.9

16 Patient Comments

Reviewed on Sep 5, 2019

Dr. Kalaycio is a wonderful, caring physician who always makes me feel like I am the most important thing to him.

Reviewed on Aug 20, 2019

Doc K is the best period.

Reviewed on Jul 12, 2019

Dr. Kalaycio is wonderful . I feel very very lucky that he is my Dr.

Reviewed on Jun 18, 2019

Dr. Kalaycio was extremely pleasant and well prepared for my visit. I especially was impressed when he knew the whole history of my illness from diagnosis to present status. He took the time to make sure I understood what my options were and gave me and my family members to ask all off our questions.

Reviewed on May 6, 2019

Dr. Kalaycio was very informative, friendly, honest and caring. Him and his team made me feel very comfortable and addressed all of my questions and concerns with details and supporting visual aids. I came all the way from Cincinnati because I heard the Cleveland Clinic was one of the best places and Dr. Kalaycio and his team didn't disappoint.

Reviewed on Apr 25, 2019

Great Doctor knows illness always answers question in commercial term. Trust him!

Reviewed on Apr 8, 2019

*Dr. Kalaycio was wonderful we are just starting this journey and I feel very blessed that he is my doctor.

Reviewed on Mar 28, 2019

Dr. Kalaycio is absolutely amazing-- clinically astute and absolutely kind. A perfect combination!!!

Reviewed on Mar 28, 2019

A first class experience from a World class physician. I am constantly amazed that I can have my case evaluated a physician of his caliber and astounded that can actually be seen by him personally. Thank you!!!

Reviewed on Mar 5, 2019

Dr. Kalaycio was a great help with my issues at hand. It was a great experience.

Reviewed on Jan 29, 2019

Dr. Kalaycio's. demeanor, professionalism and compassion were exemplary.The same level of professionalism was exhibited by everyone I dealt with during my visit.Thanks to all delivering quality services.

Reviewed on Jan 21, 2019

Dr. Kalaycio is the best doctor I have ever had. Anyone would be lucky to have him fighting for you. The Cleveland Clinic has a top notch doctor

Reviewed on Jan 21, 2019

Very nice people. I was impressed when the doctor explained my myeloma and the way for treatment.

Reviewed on Dec 18, 2018

I see Dr. Kalaycio every six months to monitor CLL. he makes my appointment schedule and I receive notification via My Chart.Blood tests are also scheduled for the same day as the consultation which makes it easy.Regarding questions about prescription medication, medication was prescribed by my primary care physician and unrelated to the CLL condition for which I see Dr. Kalaycio

Reviewed on Dec 11, 2018

dr. Kalaycio was wounderful.

Reviewed on Nov 6, 2018

Have never had to wait any longer than 15 minutes to see Dr.K in 8 years.

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