Department Ophthalmology
Primary Location Cleveland Clinic Main Campus
Type of Doctor Both Adults and Children & Adolescents
Languages English
Surgeon Yes
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus

Specialties & Treatments

Treatment & Services

  • Ophthalmology
  • Pediatric Ophthalmology
View all 2 Treatment & Services +

Specialty in Diseases & Conditions

  • Age-Related Macular Degeneration
  • Pediatric Retinal Detachment
  • Retinal Disorders
  • Retinitis
View all 4 Specialties +


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About Jonathan Sears, MD

Jonathan Sears, MD, is Associate Professor of Ophthalmology at the Cole Eye Institute, Cleveland Clinic. He received his undergraduate education at Yale College, graduating cum laude with a BS in chemistry. He continued with medical school at Yale University School of Medicine, where he developed a novel method of screening B-cell epitopes, which was used to help develop the Lyme vaccine. He was a Resident in Ophthalmology at Yale as well, and next completed a two-year surgical fellowship at Emory University, where he developed an interest in pediatric retinal detachment and retinopathy of prematurity (ROP).

Dr. Sears' research interest is in ROP. He uses a mouse model of ROP to test the hypothesis that small-molecule activators of hypoxia-inducible factor are able to drive retinal development early in life to prevent ROP detachment.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Emory University Hospital
Vitreoretinal Fellowship
Decatur, GA USA

Residency - Yale-New Haven Hospital
New Haven, CT USA

Internship - Yale-New Haven Hospital
Internal Medicine
New Haven, CT USA

Medical School - Yale University School of Medicine
New Haven, CT USA

Undergraduate - Yale University
New Haven, CT USA

Professional Highlights

  • AAO Achievement Award
  • The Hartwell Foundation Research Fellow
  • Matilda Zeigler Foundation Research Fellow


  • Ophthalmology

Specialty Interests

retinal detachment secondary to degenerative disorders such as myopia or trauma or diabetes, retinopathy of prematurity and other acquired vitreoretinal diseases, vitreoretinal diseases, pediatric retina

Awards & Honors

  • Distinction in Chemistry, Department of Chemistry, Yale University, 1988$0$0Cum Laude, Yale University, 1988
  • Yale Medical Student Research Fellowship, sponsored by National Institutes of Health; Howard Hughes Medical Institute, Section of Immunobiology, Yale School of Medicine, 1990-1992
  • Harold J. Lamport Prize, awarded for the most creative biomedical research by a Yale medical student, Department of Biochemistry, Yale School of Medicine, 1992
  • Yale Resident Research Prize, Department of Ophthalmology, 1995 and 1996
  • Heed Ophthalmic Fellowship, in support of clinical research, 1997
  • Emory Medical Care Fellowship, in support of basic science research, Emory University School of Medicine, 1997
  • Association of University Professors of Ophthalmology, Fellow Research Competition, Finalist, 1998
  • Clinical Teacher of the Year Award, Department of Ophthalmology, Emory University School of Medicine, 1998
  • Clinical Investigator Development Award, Cleveland Clinic, 2003
  • Best Doctors in America, 2005-2009
  • Best Doctors in Cleveland, 2005-2009
  • American Academy of Ophthalmology Achievement Award, 2007
  • Editorial Board Member Online News and Education (O.N.E.), 2007
  • Editorial Board Member British Journal of Ophthalmology
  • Best Research, Poster American Academy of Ophthalmology, 2008
  • Strathmore Who's Who 2009

Innovations & Patents

  • Stimulating angiogenesis to prevent ischemic retinopathy


  • American Academy of Ophthalmology
  • Association of Research in Vision and Ophthalmology
  • International Congress of Eye Research
  • Association of Pediatric Retinal Surgeons
  • Cleveland Ophthalmic Society
  • Heed Ophthalmic Society$0$0
Research & Publications

Research & Publications

See publications for Jonathan Sears, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 10/10/2017, Dr. Sears has reported no financial relationship with industry that is applicable to this listing. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

223 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.8 out of 5
Explains 4.9
Listens 4.9
Courtesy, Respect & Concern 4.9
Knows Medical History 4.8
Time Spent with Patient 4.8
Patient Rating of Doctor 4.8

21 Patient Comments

Reviewed on Jan 16, 2018

Dr. Sears is a very caring, professional doctor. He has been a great help to me with my eye problem.

Reviewed on Jan 16, 2018

Dr. Sears is technically very strong. What makes the monthly appointments more tolerable (since the appointment ends with someone inserting a needle in my eye) is Dr. Sears personality. He shows genuine interest and concern for my well being - and as a person. He also asks for my input when circumstances warrant.

Reviewed on Dec 21, 2017

I also was given information about my vision and glasses prescription. this was also very much appreciated. But the diagnosis that I do not have age-related macular degeneration was the best!

Reviewed on Dec 21, 2017

This person also suggested that I request to be transported back to the parking garage via shuttle when my appointment was concluded. I had walked, it was a cold,windy morning. I found this very considerate. Thanks!

Reviewed on Nov 21, 2017

Dr. Sears has gone above and beyond what we ever could have expected from a care provider for our daughter! Him and his entire staff are excellent!

Reviewed on Oct 19, 2017

I drive 5 hours each way to see Dr. Sears

Reviewed on Oct 3, 2017

He was sarcastic and unsympathetic.

Reviewed on Sep 28, 2017

Dr. Sears and his entire team is exceptional!

Reviewed on Aug 29, 2017

Excellent doctor. Thorough and good rapport with patient.

Reviewed on Aug 15, 2017

Dr. Sears needs improvement on his bed side manner.

Reviewed on Aug 1, 2017

clear, concise instructions.

Reviewed on Jul 20, 2017

Dr. Sears saved my eye sight need I say more?

Reviewed on Jul 3, 2017

Had a long wait in exam area - would help if a reason for the delay was given.

Reviewed on Jun 1, 2017

Always exceptional.

Reviewed on May 23, 2017

Excellent care.

Reviewed on Apr 20, 2017

staff and physician always speak to my son- who is almost 17. direct questions to him- not me. Love that- he feels he is part of his care

Reviewed on Apr 11, 2017

Very good.

Reviewed on Apr 11, 2017

Very good.

Reviewed on Apr 6, 2017

very good

Reviewed on Apr 4, 2017

great experience

Reviewed on Mar 7, 2017

Dr. Sears and Christine are excellent.

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