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Department Ophthalmology
Primary Location Cleveland Clinic Main Campus
Type of Doctor Both Adults and Children & Adolescents
Languages English
Surgeon Yes
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus

Specialties & Treatments

Treatment & Services

  • Epiretinal Membrane Surgery
  • Fluorescein Angiography
  • Intravitreal Injections for Retinal Disease
  • Laser for Diabetic Retinopathy
  • Macular Degeneration Evaluations
  • Management of Age Related Macular Degeneration (AMD)
  • Microincision Vitrectomy Surgery
  • Ophthalmic Surgery
  • Ophthalmology
  • Optical Coherence Tomography
  • Pars Plana Vitrectomy
  • Pediatric Ophthalmology
  • Retinal Laser Surgery
  • Scleral Buckle
  • Surgical and Medical Treatment of the Retina
  • Sutureless (Small Gauge) Retinal Surgery
  • Vitreoretinal Surgery
View all 17 Treatment & Services +

Specialty in Diseases & Conditions

  • Age-Related Macular Degeneration
  • Diabetic Retinopathy
  • Diseases of the Vitreous
  • Lens Dislocation
  • Macular Hole
  • Macular Pucker
  • Pediatric Retinal Detachment
  • Retinal Detachment
  • Retinal Diseases
  • Retinal Disorders
  • Retinal Hemangioma
  • Retinal Pigment Epithelium-Choroid Complex
  • Retinal Vein Occlusion
  • Retinitis
  • Traumatic Retinal Detachment
View all 15 Specialties +


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About Jonathan Sears, MD

Jonathan Sears, MD, is Associate Professor of Ophthalmology at the Cole Eye Institute, Cleveland Clinic. He received his undergraduate education at Yale College, graduating cum laude with a BS in chemistry. He continued with medical school at Yale University School of Medicine, where he developed a novel method of screening B-cell epitopes, which was used to help develop the Lyme vaccine. He was a Resident in Ophthalmology at Yale as well, and next completed a two-year surgical fellowship at Emory University, where he developed an interest in pediatric retinal detachment and retinopathy of prematurity (ROP).

Dr. Sears' research interest is in ROP. He uses a mouse model of ROP to test the hypothesis that small-molecule activators of hypoxia-inducible factor are able to drive retinal development early in life to prevent ROP detachment.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Emory Eye Clinic
Vitreoretinal Fellowship
Atlanta, GA USA

Residency - Yale-New Haven Hospital
New Haven, CT USA

Internship - Yale-New Haven Hospital
Internal Medicine
New Haven, CT USA

Medical Education - Yale University School of Medicine
New Haven, CT USA

Undergraduate - Yale University
New Haven, CT USA

Professional Highlights

  • AAO Achievement Award
  • The Hartwell Foundation Research Fellow
  • Matilda Zeigler Foundation Research Fellow


  • Ophthalmology

Specialty Interests

retinal detachment secondary to degenerative disorders such as myopia or trauma or diabetes, retinopathy of prematurity and other acquired vitreoretinal diseases, vitreoretinal diseases, pediatric retina

Awards & Honors

  • Distinction in Chemistry, Department of Chemistry, Yale University, 1988$0$0Cum Laude, Yale University, 1988
  • Yale Medical Student Research Fellowship, sponsored by National Institutes of Health; Howard Hughes Medical Institute, Section of Immunobiology, Yale School of Medicine, 1990-1992
  • Harold J. Lamport Prize, awarded for the most creative biomedical research by a Yale medical student, Department of Biochemistry, Yale School of Medicine, 1992
  • Yale Resident Research Prize, Department of Ophthalmology, 1995 and 1996
  • Heed Ophthalmic Fellowship, in support of clinical research, 1997
  • Emory Medical Care Fellowship, in support of basic science research, Emory University School of Medicine, 1997
  • Association of University Professors of Ophthalmology, Fellow Research Competition, Finalist, 1998
  • Clinical Teacher of the Year Award, Department of Ophthalmology, Emory University School of Medicine, 1998
  • Clinical Investigator Development Award, Cleveland Clinic, 2003
  • Best Doctors in America, 2005-2009
  • Best Doctors in Cleveland, 2005-2009
  • American Academy of Ophthalmology Achievement Award, 2007
  • Editorial Board Member Online News and Education (O.N.E.), 2007
  • Editorial Board Member British Journal of Ophthalmology
  • Best Research, Poster American Academy of Ophthalmology, 2008
  • Strathmore Who's Who 2009

Innovations & Patents

  • Stimulating angiogenesis to prevent ischemic retinopathy


  • American Academy of Ophthalmology
  • Association of Research in Vision and Ophthalmology
  • International Congress of Eye Research
  • Association of Pediatric Retinal Surgeons
  • Cleveland Ophthalmic Society
  • Heed Ophthalmic Society$0$0
Research & Publications

Research & Publications

See publications for Jonathan Sears, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 8/17/2023, Dr. Sears has reported no financial relationship with industry that is applicable to this listing. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

340 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.9 out of 5
Explains 4.9
Courtesy, Respect & Concern 4.9
Patient Rating of Doctor 4.9

59 Patient Comments

Reviewed on Jan 9, 2024

Dr Sears is kind and extremely knowledgeable. His skill has saved my sight. I will be eternally grateful for the exceptional care I received at Cleveland Clinic

Reviewed on Dec 12, 2023

Dr. Sears is very easy to communicate with and provides exceptional care. One can not expect more.

Reviewed on Dec 12, 2023

Our family feels that Dr. Sears is very professional and trust him with our daughter's medical care. The Fellow at this visit was also very kind & confident. Thank you.

Reviewed on Dec 7, 2023

Dr. Sears always discusses his decisions about my treatments which I appreciate

Reviewed on Dec 5, 2023

The Dr usually seems rushed and I would like to have more time to discuss my complicated case even if it resulted in higher charges. All of my questions do not always get answered.

Reviewed on Dec 5, 2023

Dr. Sears has treated my late Father and myself for 20 years. He is superb in every way. The doctors, nurses, and technicians that assist him are equally excellent. I consider myself to be most fortunate to be in his care.

Reviewed on Dec 5, 2023

Dr. Sears is the best!

Reviewed on Nov 28, 2023

Dr. Sears was very understanding when I raised a wish to find a practitioner closer to my home. He offered to work with any specialist I may find for eye injections.

Reviewed on Nov 9, 2023

Dr. Sears and Laura were very professional, knowledgeable and attentive to my needs. The only negative comment that I would add was the long wait time.

Reviewed on Nov 9, 2023

Dr. Sears always explains clearly to me information about my results and condition and informs me about what steps I need to consider concerning my condition. Never had a bad experience with Dr. Sears' ability

Reviewed on Nov 9, 2023

First saw a fellow. She was great. Sure how she stays with CCF. Then met Dr Sears. A++ for his time and talents. He will be doing my surgery.

Reviewed on Nov 7, 2023

Dr Sears is always very kind . He truly cares about this patients.

Reviewed on Nov 7, 2023

Dr. Sears is an excellent physician

Reviewed on Nov 7, 2023

Because of driving distance, scheduler is good working with us for appointments. Staff is respectful, professional and caring. Dr Sears is an outstanding specialist.

Reviewed on Nov 7, 2023

Dr has shown professional concern with my condition. Dr encourages me and has a positive attitude despite the issues I have experienced.. My journey with Dr Sears began in May. Two surgeries and many trips to Cleveland Clinic. He is the BEST

Reviewed on Nov 7, 2023

Dr. Sears encourages frequent follow-ups and addresses problems without delay. When I needed next day surgery, Dr. Sears didn't hesitate to add me on his busy surgery schedule to prevent further damage to my eye.

Reviewed on Nov 7, 2023

Dr. Sears' team is amazing, nurses and schedulers work there for a long time and have experience and compassion

Reviewed on Oct 24, 2023

Very pleased with my appointment. Dr Sears did a great job informing me about my condition and the results of my tests He explained everything very well. Dr Sears was very courteous and friendly. Look forward to seeing him at my next appointment.

Reviewed on Oct 24, 2023

The doctor that performed the eye injection was the best yet. Almost no eye irritation or pain.Blood in eye minimal.

Reviewed on Oct 19, 2023

Staff and Dr Sears are wonderful.

Reviewed on Oct 12, 2023

Dr. Sears is very good. His resident was very helpful and listened.

Reviewed on Oct 5, 2023

Dr. Sears is excellent in explaining treatment options and his manner is encouraging and calming.

Reviewed on Oct 5, 2023

For Dr. Sears' services, I would not mind travelling from any part of the world. Absolutely a great doctor. He treats me like one of his own family members. I am quite at ease to avail his services. I am extremely lucky to have him as my doctor. Thanks a lot Dr. Sears and Cleveland Clinic.

Reviewed on Sep 26, 2023

Dr Sears is a wonderful doctor but scheduling patients close together and having them wait inordinate amounts of time is unfair to the patient

Reviewed on Sep 26, 2023

Dr. Sears treats me like his own family member. For his care, I would travel from anywhere in the world.

Reviewed on Sep 5, 2023

You have the best in dr sears my fear of drs is lessened through his compassionate care

Reviewed on Sep 5, 2023

Dr. Sears gave me showed me graphs, and gave me good explanations of my visual problems, as well as a good outlook in the future.

Reviewed on Aug 29, 2023

Great Doctor. Very Compassionate with great Communication.

Reviewed on Aug 29, 2023

Dr sears is one of the best physicians I have ever had. I have 100% trust of his care of me.

Reviewed on Aug 29, 2023

Phone wait time is often frustrating when trying to schedule an appointment or reach the doctor's office.

Reviewed on Aug 29, 2023

Dr sears is a great doctor

Reviewed on Aug 17, 2023

I continue to greatly appreciate Dr Sears' technical expertise AND the manner in which he deals with patients. He Is a real person and makes you feel like a real person who is being taken care of.

Reviewed on Aug 17, 2023

I completly trust Dr. Sears, he always takes time to do thorough exam, answer questions and schedules regular follow-ups

Reviewed on Aug 8, 2023

Dr. Sears is very patient and he listens to any concerns. No rushing.

Reviewed on Aug 1, 2023

Dr. Sears is THE BEST!

Reviewed on Jul 13, 2023

Dr Sears is the consummate doctor. He does a great job. Covers all questions & explains things such that a nonprofessional understands

Reviewed on Jul 13, 2023

Dr. Sears and his staff have always been outstanding in their care for me and my family.

Reviewed on Jul 6, 2023

Dr Sears has always been very thorough in explaining the procedure and the follow through Instructions. He cares about the patient and works to ensure the best outcome. MHe shows compassion and care that he is truly concerned about you as his patient. Would highly recommend Dr Sears for his knowledge and procedure to restore vision after an injury

Reviewed on Jul 6, 2023

So glad I was referred to Dr Sears! Although the drive is 2 1/2 hours, it is worth every minute knowing his care is helping to restore/improve my vision. He is one amazing Dr.

Reviewed on Jul 6, 2023

The wait to see the doctor is to long. Appointment was at 9:30 didn't see doctor for three hours. To long for a senior citizen to sit.

Reviewed on Jun 22, 2023

My experience with both Dr. Sears and his staff is always excellent.

Reviewed on Jun 20, 2023

Dr. Sears is truly exceptional!!

Reviewed on Jun 6, 2023

Dr. Sears shows compasion and listens.

Reviewed on Jun 6, 2023

I always recommend Dr. Sears to those who have vision Issues and could benefit from his skills.

Reviewed on Jun 6, 2023

Dr. Sears is terrific. I always recommend him and Cole Eye Institute whenever I know of someone needing help.

Reviewed on Jun 1, 2023

Dr sears always makes me feel very comfortable with him He is very pleasant to talk to and I trust his medical opinions! His interns have also treated me very nicely !

Reviewed on May 25, 2023

Dr Sears is the Absolute best

Reviewed on May 16, 2023

Dr Sears was very attentive to my eye condition. He listens in detail to my concerns and told us what to expect on our next visit. Very informative.

Reviewed on May 9, 2023

Great experience! Dr Sears and his staff are awesome!!! Dr. Sears is an outstanding Ophthalmologist with wisdom and caring spirit.

Reviewed on May 9, 2023


Reviewed on Apr 4, 2023

Dr. Sears was wonderful. He explained my situation and course for going forward.

Reviewed on Mar 30, 2023

Dr Sears is doing everything possible to treat and save my vision

Reviewed on Mar 28, 2023

Dr. Sears saved my eyesight. He is always courteous, informative and a good listener.

Reviewed on Mar 14, 2023

Love, love, love Dr. Sears....he is very down to earth, and compassionate.

Reviewed on Mar 14, 2023

Dr. Sears is a terrific physician. I respect and value his advice.

Reviewed on Mar 9, 2023

I believe if it was not for Dr. Sears and his immediate reaction to my problem, My outcome may have been different. He showed great passion, concern and most important created the right solution.

Reviewed on Feb 21, 2023

I have had the same doctor for many years & he has always been very helpful and patient.

Reviewed on Feb 21, 2023

As stated, he was quite an amazing doctor. Really cares.

Reviewed on Feb 7, 2023

*Dr. Sears has always provided excellent care.

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