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Department Ophthalmology
Primary Location Cleveland Clinic Main Campus
Type of Doctor Both Adults and Children & Adolescents
Languages English
Surgeon Yes
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus

Specialties & Treatments

Treatment & Services

  • Ophthalmology
  • Pediatric Ophthalmology
View all 2 Treatment & Services +

Specialty in Diseases & Conditions

  • Age-Related Macular Degeneration
  • Pediatric Retinal Detachment
  • Retinal Disorders
  • Retinitis
View all 4 Specialties +


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About Jonathan Sears, MD

Jonathan Sears, MD, is Associate Professor of Ophthalmology at the Cole Eye Institute, Cleveland Clinic. He received his undergraduate education at Yale College, graduating cum laude with a BS in chemistry. He continued with medical school at Yale University School of Medicine, where he developed a novel method of screening B-cell epitopes, which was used to help develop the Lyme vaccine. He was a Resident in Ophthalmology at Yale as well, and next completed a two-year surgical fellowship at Emory University, where he developed an interest in pediatric retinal detachment and retinopathy of prematurity (ROP).

Dr. Sears' research interest is in ROP. He uses a mouse model of ROP to test the hypothesis that small-molecule activators of hypoxia-inducible factor are able to drive retinal development early in life to prevent ROP detachment.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Emory University Hospital
Vitreoretinal Fellowship
Decatur, GA USA

Residency - Yale-New Haven Hospital
New Haven, CT USA

Internship - Yale-New Haven Hospital
Internal Medicine
New Haven, CT USA

Medical Education - Yale University School of Medicine
New Haven, CT USA

Undergraduate - Yale University
New Haven, CT USA

Professional Highlights

  • AAO Achievement Award
  • The Hartwell Foundation Research Fellow
  • Matilda Zeigler Foundation Research Fellow


  • Ophthalmology

Specialty Interests

retinal detachment secondary to degenerative disorders such as myopia or trauma or diabetes, retinopathy of prematurity and other acquired vitreoretinal diseases, vitreoretinal diseases, pediatric retina

Awards & Honors

  • Distinction in Chemistry, Department of Chemistry, Yale University, 1988$0$0Cum Laude, Yale University, 1988
  • Yale Medical Student Research Fellowship, sponsored by National Institutes of Health; Howard Hughes Medical Institute, Section of Immunobiology, Yale School of Medicine, 1990-1992
  • Harold J. Lamport Prize, awarded for the most creative biomedical research by a Yale medical student, Department of Biochemistry, Yale School of Medicine, 1992
  • Yale Resident Research Prize, Department of Ophthalmology, 1995 and 1996
  • Heed Ophthalmic Fellowship, in support of clinical research, 1997
  • Emory Medical Care Fellowship, in support of basic science research, Emory University School of Medicine, 1997
  • Association of University Professors of Ophthalmology, Fellow Research Competition, Finalist, 1998
  • Clinical Teacher of the Year Award, Department of Ophthalmology, Emory University School of Medicine, 1998
  • Clinical Investigator Development Award, Cleveland Clinic, 2003
  • Best Doctors in America, 2005-2009
  • Best Doctors in Cleveland, 2005-2009
  • American Academy of Ophthalmology Achievement Award, 2007
  • Editorial Board Member Online News and Education (O.N.E.), 2007
  • Editorial Board Member British Journal of Ophthalmology
  • Best Research, Poster American Academy of Ophthalmology, 2008
  • Strathmore Who's Who 2009

Innovations & Patents

  • Stimulating angiogenesis to prevent ischemic retinopathy


  • American Academy of Ophthalmology
  • Association of Research in Vision and Ophthalmology
  • International Congress of Eye Research
  • Association of Pediatric Retinal Surgeons
  • Cleveland Ophthalmic Society
  • Heed Ophthalmic Society$0$0
Research & Publications

Research & Publications

See publications for Jonathan Sears, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 10/14/2020, Dr. Sears has reported no financial relationship with industry that is applicable to this listing. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

295 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.8 out of 5
Explains 4.8
Courtesy, Respect & Concern 4.9
Patient Rating of Doctor 4.8

79 Patient Comments

Reviewed on May 20, 2021

Dr. Sears was extremely helpful and informative

Reviewed on May 18, 2021

Dr. Sears is fantastic, lots to do with seeing so many patients in a day ! well done !!

Reviewed on May 18, 2021

Dr s nurse excellent job

Reviewed on May 18, 2021

Dr. Sears is the best! I would recommend his 100% to friends, family and "strangers."

Reviewed on May 18, 2021

Dr. Sears is superb. Everyone in his practice are first rate.

Reviewed on May 6, 2021

I was expecting a discussion about concurrent procedures to fix problems I was having as in past appointments. this time the recommendation changed which made me uncomfortable that something changed with my condition or the doctors anticipated outcome.

Reviewed on May 6, 2021

Dr. Sears is very good and listens to what I have to say. He is also very knowlegable and I have the greatest of confidence in him.

Reviewed on May 4, 2021

best doc and staff I ever had

Reviewed on Apr 22, 2021

Dr Sears is personable, his bedside manner is exceptional he takes time to answer any questions asked of him. i felt confident having him as my doctor.

Reviewed on Apr 22, 2021

Dr Sears and staff were all of what I expected from care givers

Reviewed on Apr 22, 2021

Always a good experience with Doctor Sears

Reviewed on Apr 20, 2021

Doctor very courteous and professional. Easy to discuss my problem with him.

Reviewed on Apr 20, 2021

Doctor was professional but old school (not interested in listening to me, just in himself talking). I didn't ask some questions I wanted because I felt rushed.

Reviewed on Apr 15, 2021

Dr Sears is outstanding & a credit to the Clinic. At my age I deal & have delt with many doctors & he is one of the best, if not the best. You are lucky to have him.

Reviewed on Apr 13, 2021

dr. Sears is a wonderful doctor

Reviewed on Apr 13, 2021

wonderful doctor would highly recommend him to friends and family

Reviewed on Apr 6, 2021

Dr. Sears is always kind and attentive to my concerns. I agreed to see him because of my past interactions with him.

Reviewed on Mar 30, 2021

Dr Sears, and his staff are wonderful, as busy as they are I always feel like I am the only patient there.

Reviewed on Mar 25, 2021

Dr. Sears is a fabulous asset for the Clinic. Outstanding physician and human being..........

Reviewed on Mar 23, 2021

dr. sears staff is fantastic

Reviewed on Mar 18, 2021

Dr. Sears was very nice.

Reviewed on Mar 16, 2021

Dr. Sears is simply amazing to work with and genuinely cares about my son. This has not been an easy journey for us, but Dr. Sears has made it a great experience. He is thorough and explains things very well. My son always looks forward to our visits, and I think that's a true indication of the care even a young boy feels he's getting. He is never afraid to go see Dr. Sears!

Reviewed on Mar 16, 2021

Dr. Sears is the best

Reviewed on Mar 9, 2021

I now consider Dr. Sears my ophthalmologist. He was excellent.

Reviewed on Mar 9, 2021

Dr. Sears has a resident that came in and did a preliminary eye check and was kind and personable.

Reviewed on Feb 25, 2021

Dr. Sears is one of the best things to happen to our child.

Reviewed on Feb 23, 2021

Dr. Sears is very caring and concerned about my family and me.We never feel like he is rushing our appointments!

Reviewed on Feb 23, 2021

I already recommend Dr. Sears and the Cole Eye Clinic. You guys saved my sight.

Reviewed on Feb 9, 2021

I have repeatedly recommended Dr. Sears to others.

Reviewed on Feb 2, 2021

Dr Mendell and Dr Sears were wonderful.... thorough, professional, and simply the best!!

Reviewed on Jan 21, 2021

great doctor and nurse

Reviewed on Jan 21, 2021

excellent capable staff and doctor

Reviewed on Jan 21, 2021

Dr. Sears is a very trusted doctor. His attention to detail and his concern is outstanding. He is someone I admire and is an example of the character and the integrity of the CCF. Hats off to him.

Reviewed on Jan 21, 2021

Kudos to Dr. Sears !!

Reviewed on Jan 12, 2021

Dr. Jonathan Sears has never disappointed me. He takes time to discuss my eye condition and his concern is evident.

Reviewed on Jan 12, 2021

was very worried about an eye injury before appointment. Dr. Sears explained the situation so I could understand it and not worry.

Reviewed on Jan 12, 2021

Dr. Sears is the best doctor in the world as far as I am concerned. I have been able to have a normal life after he operated on my serious eye problems.

Reviewed on Jan 5, 2021

great doctors!!!

Reviewed on Dec 8, 2020

*Dr. Sears is very knowledgeable and treats me with respect.

Reviewed on Dec 8, 2020

Dr. Sears, as well as the fellow, was very thorough and explained things well.

Reviewed on Dec 3, 2020

Dr. Sears is the best. No question.

Reviewed on Nov 19, 2020

I made a mistake and arrived to my appointment on the wrong day. However, the office and Dr. Sears were able to make time for me. I had driven from Buffalo, NY. I appreciated that very much!

Reviewed on Oct 29, 2020

very renowned provider

Reviewed on Oct 22, 2020

Dr. Jonathon Sears is not only a skilled surgeon, but he has an exceptional rapport with, I am certain, all of his patients!!! At all times, with many follow-up visits, I not only was attended by a man with true love for humanity and the joy of healing and improving quality of life, I MADE A FRIEND!!!! My confidence in his skill and ability is in my high esteem!!! I am a retired educator, 50 years experience!!! At this point I know a gifted, talented caring person when I work with him!!!!

Reviewed on Sep 29, 2020

Everyone was wonderful, I love Dr. Sears!

Reviewed on Sep 29, 2020

Dr. Sears and Dr. Mammo are the most skilled. smart, empathetic and personable doctors I have met. I am always anxious about my condition and they encourage me and give me hope. my laser surgeries have improved my vision immensely. Seeing them is worth a three hour drive...I would travel from anywhere to be treated by these doctors.

Reviewed on Sep 29, 2020

the doctor is amazing but getting an appointment schedule can be rather hard at times.

Reviewed on Sep 22, 2020

It was my first time seeing Dr. Sears and I was very pleased with him I would highly recommend him to others

Reviewed on Sep 22, 2020

dr sears and dr mammo were helpful and made sure I was aware of and comfortable with my options and choices

Reviewed on Sep 22, 2020

dr.sears saved my eye !!!!

Reviewed on Sep 15, 2020

Dr. Sears is by far the very best!!!!

Reviewed on Sep 15, 2020

Dr. Sears is an excellent doctor who we have a lot of faith in. Always have good relation with him and conversations. He takes the time to talk with us. Thanks.

Reviewed on Sep 8, 2020

doctor Sears went above and beyond in answering a question we asked

Reviewed on Sep 3, 2020

Dr Sears, Christine and medical team always listen to my concerns and explain test results

Reviewed on Aug 20, 2020

Dr Sears was excellent... he listed thoroughly and made sure I understood what to do moving forward.

Reviewed on Aug 11, 2020

Dr. Sears always keeps his appointments upbeat.

Reviewed on Aug 11, 2020

dr.Sears and his have been very polite and helpful

Reviewed on Aug 11, 2020

Dr. Sears is always very professional, personable, and provides excellent explanations.

Reviewed on Jul 30, 2020

I always had a great visit with the doctor no complaints

Reviewed on Jul 28, 2020

Dr. Sears and his team went above and beyond to answer my questions. They were a great source of support and comfort during this most difficult time.

Reviewed on Jul 28, 2020

Dr. Sears knows his stuff!

Reviewed on Jul 28, 2020

dr Sears is an excellent doctor.

Reviewed on Jul 28, 2020

Dr. Sears is wonderful!

Reviewed on Jul 28, 2020

Always satisfied with Dr. Sears

Reviewed on Jul 23, 2020

I actually look forward to going to the Clinic as I always experience professional care and concern that all companies should emulate. The Cleveland Clinic continues to exceed my expectations. I hold my personal Doctor Jonathan Sears in the highest regard, I know I'm getting the best care possible.

Reviewed on Jul 21, 2020

Dr. Sears and Christine are the BEST

Reviewed on Jul 16, 2020

Dr, Sears, is a great dr. I feel confident to his evaluation

Reviewed on Jul 14, 2020

My wife has been a patient of Dr. Sears since 2014 and although we drive in from Buffalo, NY, we will not go to anyone else. That's why since I had an issue with my left eye, I made an appointment with Dr. Sears for a second opinion.

Reviewed on Jul 14, 2020

Excellent physician, I feel very fortunate to have him as my Doctor.

Reviewed on Jun 25, 2020

Originally scheduled for April, but I was thrilled that I could get in to see Dr. Sears in June.

Reviewed on Jun 25, 2020

I have all the confidence in the world in Dr. Sears. I always share his name with friends!

Reviewed on Jun 16, 2020

I feel very blessed to have had Dr Sears as my doctor since the beginning of my eye condition. He has helped & encouraged me & given me excellent, excellent care! He's very knowledgeable & I feel very safe in his care.

Reviewed on Jun 16, 2020

best doc i ever had !!!

Reviewed on Jun 11, 2020

Dr Sears and Christine Sonny are always personable and professional.

Reviewed on Jun 11, 2020

It is always a pleasure to see Dr Sears and his staff!

Reviewed on Jun 11, 2020

good experience with Dr Sears

Reviewed on Jun 9, 2020

Always a great experience with Dr. Sears and his staff.

Reviewed on Jun 9, 2020

My visit with Dr. Jonathon E. Sears was fruitful as always. I had to chuckle when I asked about the whereabouts of Dr. Cowel. The nurse commented that Dr. Cowel was an excellent doctor. I knew that, but that is what I expect. This is The Cleveland Clinic, after all. My so. told me how good his Russian eye doctor was, but I still believe that Dr. Sears is the best,

Reviewed on Jun 9, 2020

Dr Sears is outstanding physician who has been a tremendous help in increasing my vision and helping to control my diabetes. Great staff very professional and extremely kindhearted.

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