Department Ophthalmology
Primary Location Cleveland Clinic Main Campus
Type of Doctor Both Adults and Children & Adolescents
Languages English
Surgeon Yes
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus


Additional Locations

Specialties & Treatments

Treatment & Services

  • Ophthalmology
  • Pediatric Ophthalmology
View all 2 Treatment & Services +

Specialty in Diseases & Conditions

  • Age-Related Macular Degeneration
  • Pediatric Retinal Detachment
  • Retinal Disorders
  • Retinitis
View all 4 Specialties +


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About Jonathan Sears, MD

Jonathan Sears, MD, is Associate Professor of Ophthalmology at the Cole Eye Institute, Cleveland Clinic. He received his undergraduate education at Yale College, graduating cum laude with a BS in chemistry. He continued with medical school at Yale University School of Medicine, where he developed a novel method of screening B-cell epitopes, which was used to help develop the Lyme vaccine. He was a Resident in Ophthalmology at Yale as well, and next completed a two-year surgical fellowship at Emory University, where he developed an interest in pediatric retinal detachment and retinopathy of prematurity (ROP).

Dr. Sears' research interest is in ROP. He uses a mouse model of ROP to test the hypothesis that small-molecule activators of hypoxia-inducible factor are able to drive retinal development early in life to prevent ROP detachment.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Emory University Hospital
Vitreoretinal Fellowship
Decatur, GA USA

Residency - Yale-New Haven Hospital
New Haven, CT USA

Internship - Yale-New Haven Hospital
Internal Medicine
New Haven, CT USA

Medical Education - Yale University School of Medicine
New Haven, CT USA

Undergraduate - Yale University
New Haven, CT USA

Professional Highlights

  • AAO Achievement Award
  • The Hartwell Foundation Research Fellow
  • Matilda Zeigler Foundation Research Fellow


  • Ophthalmology

Specialty Interests

retinal detachment secondary to degenerative disorders such as myopia or trauma or diabetes, retinopathy of prematurity and other acquired vitreoretinal diseases, vitreoretinal diseases, pediatric retina

Awards & Honors

  • Distinction in Chemistry, Department of Chemistry, Yale University, 1988$0$0Cum Laude, Yale University, 1988
  • Yale Medical Student Research Fellowship, sponsored by National Institutes of Health; Howard Hughes Medical Institute, Section of Immunobiology, Yale School of Medicine, 1990-1992
  • Harold J. Lamport Prize, awarded for the most creative biomedical research by a Yale medical student, Department of Biochemistry, Yale School of Medicine, 1992
  • Yale Resident Research Prize, Department of Ophthalmology, 1995 and 1996
  • Heed Ophthalmic Fellowship, in support of clinical research, 1997
  • Emory Medical Care Fellowship, in support of basic science research, Emory University School of Medicine, 1997
  • Association of University Professors of Ophthalmology, Fellow Research Competition, Finalist, 1998
  • Clinical Teacher of the Year Award, Department of Ophthalmology, Emory University School of Medicine, 1998
  • Clinical Investigator Development Award, Cleveland Clinic, 2003
  • Best Doctors in America, 2005-2009
  • Best Doctors in Cleveland, 2005-2009
  • American Academy of Ophthalmology Achievement Award, 2007
  • Editorial Board Member Online News and Education (O.N.E.), 2007
  • Editorial Board Member British Journal of Ophthalmology
  • Best Research, Poster American Academy of Ophthalmology, 2008
  • Strathmore Who's Who 2009

Innovations & Patents

  • Stimulating angiogenesis to prevent ischemic retinopathy


  • American Academy of Ophthalmology
  • Association of Research in Vision and Ophthalmology
  • International Congress of Eye Research
  • Association of Pediatric Retinal Surgeons
  • Cleveland Ophthalmic Society
  • Heed Ophthalmic Society$0$0
Research & Publications

Research & Publications

See publications for Jonathan Sears, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 9/27/2018, Dr. Sears has reported no financial relationship with industry that is applicable to this listing. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

268 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.8 out of 5
Explains 4.8
Listens 4.8
Courtesy, Respect & Concern 4.8
Knows Medical History 4.8
Time Spent with Patient 4.6
Patient Rating of Doctor 4.8

42 Patient Comments

Reviewed on Aug 29, 2019

Dr Sears and Staff excellent

Reviewed on Aug 13, 2019

Dr. Sears is the best doctor I've ever met! It's hard to come by a good doctor that also has great bedside manners. Thank you Dr. Sears!

Reviewed on Aug 8, 2019

Dr Sears is the greatest

Reviewed on Aug 6, 2019

Dr Sears is the best and I will recommend him to others!

Reviewed on Jul 30, 2019

Dr. Sears is a great doctor. I would definitely recommend him.

Reviewed on Jul 30, 2019

Dr. Sears truly cares about my case and what my concerns are. Comes in room very prepared of what medical history I have and truly shows he cares. Best doctor I have ever had.

Reviewed on Jul 25, 2019

Dr. Sears is an excellent surgeon/doctor. He is highly intelligent, compassionate, and excels at communication. His experience is comforting.

Reviewed on Jul 16, 2019

I recommend Cole Institute to whoever listens! I am both thankful and pleased by Dr. Sears abilities in saving my vision. And the entire staff, from valor service to ALL of your Dr. and nurses and techs are to be commended for their care, empathy and friendliness. Thank you one and all.

Reviewed on Jul 16, 2019

Dr. Sears and his student were very professional.

Reviewed on Jun 27, 2019

Dr. Sears has always been very caring in his treatment. I trust his judgement.

Reviewed on Jun 27, 2019

My contact with this Dr. was very brief.

Reviewed on Jun 11, 2019

I don't think you can say enough good things about Dr Sears. He is an outstanding doctor. Whatever yardstick you want to use, Dr Sears will be at the top. The Cleveland Clinic is very lucky to have him working there.

Reviewed on Jun 6, 2019

Dr. Sears is a great doctor and great person, was curious and pleasant. he answered all of my questions fully. He is a great representative to your hospital.

Reviewed on May 21, 2019

The physician and staff made the experience a good one.

Reviewed on May 9, 2019

Dr. Sears is a great eye doctor and also Christine is very courteous and helpful.

Reviewed on May 7, 2019

Part of the reason we moved from Virginia to Ohio was easy access to Cleveland Clinic. There have been no disappointments. First, Dr Cline was able to diagnose my son's GI issues and stabilize his medication, NO HOSPITALIZATIONS IN almost 2 years! that's a record for him, and Dr Jonathan Sears has managed my eyes so well I've graduated to annual visits! Also all other staff have. even wonderful!!! Thank you all.

Reviewed on May 7, 2019

Dr Sears and his staff are excellent in providing care, respect and information in a timely manner. I do not worry about decisions because of the lack of information when I have an appointment with Dr Sears and his staff

Reviewed on May 2, 2019

i am very satisfied with everyone in the practice thanks, especially dr sears himself and his nurse christine i couldnt be happier

Reviewed on Apr 25, 2019

Dr. Sears is a professional and a wonderful doctor and person. We are fortunate to have him.

Reviewed on Apr 23, 2019

I have no problem referring any one to my doctor

Reviewed on Apr 23, 2019

Dr. Sears is phenomenal; he is so courteous and attentive, I never mind the wait because I know that when I see him he gives his full attention to the appointment.

Reviewed on Apr 23, 2019

I have been seeing Dr. Sears for 11 years. He remembers me every time and can recall all of the details of my case. Not only my medical information, but he recalls details about my life and cares for me as a person as well.

Reviewed on Apr 23, 2019

Dr Sears is outstanding

Reviewed on Apr 18, 2019

Dr. Sears is a superb human being and a brilliant surgeon. He actually cares about patients as individuals and has a capacity to make you feel important. I'm very fortunate that he was assigned to repair my detached retina!

Reviewed on Apr 16, 2019

Dr. Sears was very courteous.

Reviewed on Apr 4, 2019

I have now been seeing Dr. Sears for a year for my detached retina. I would not want to see anyone else!

Reviewed on Apr 4, 2019

We have shared Dr. Sears' name with many friends in case they need a retina specialist.

Reviewed on Apr 2, 2019

the experience was informative and the advice if followed will allow me to keep my ability to see. Dr. Sears has a "bed side manner" that is comforting. His research will relieve the suffering of millions of the very young on this planet. I am humbled to be under his care. You have in your midst a Jonas Salk. He is keeping faith with the notion "To Act as a Unit". I might add "On dehalf of mankind".

Reviewed on Mar 14, 2019

a great and caring doctor. I would surely recommend his services. he put me very at ease with what I was experiencing.

Reviewed on Mar 12, 2019

Always feel that staff is truly engaged in my eye health. Dr Sears and Christine are extremely kind and care about me as an individual not just a number on a chart.

Reviewed on Mar 12, 2019

Dr. Sears is always kind and informative with my on going retina issues.

Reviewed on Mar 12, 2019

I was very pleased with Dr Sears i came to him for a second opinion He evaluated my condition and explained the diagnosis and what lies ahead Dr Sears has a comforting bedside manner Dr Sears provided me peace of mind He invited me to come back in future if i have concerns and I will

Reviewed on Mar 7, 2019

Dr. Sears has superb caring bedside manner

Reviewed on Jan 8, 2019

My visits to Dr. Sears have always been professional and courteous.

Reviewed on Dec 11, 2018

The dr. and staff were friendly and courteous.

Reviewed on Nov 27, 2018

Dr. Sears has a superb friendly and collaborative manner in discussing findings, plans, and concerns. He worked around my schedule to accommodate my surgery.

Reviewed on Nov 15, 2018

Dr. Sears has an outstanding bedside manor. I'm 100%+ confident in his skills and completely trust him with my health. I highly recommend him for anyone.

Reviewed on Nov 6, 2018

wIted for couple of hours just to be seen by doctor sears for five minutes. felt rushed because he was behind

Reviewed on Nov 6, 2018

Dr. Sears is a world-class physician, and a friendly and excellent person. I recommend him to anyone.

Reviewed on Nov 1, 2018

Jonathan Sears is the best doctor ever!

Reviewed on Oct 30, 2018

Dr. Sears and his staff are excellent. My mother came for a second opinion and we are continuing treatment with Dr. Sears. If I had a retinal problem, I would see him . I would recommend him to anyone.

Reviewed on Oct 11, 2018

Dr. Sears and his is staff work diligently to ensure each patient gets the attention they need. Keep up that great work.

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