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Department Ophthalmology
Primary Location Cleveland Clinic Main Campus
Type of Doctor Both Adults and Children & Adolescents
Languages English
Surgeon Yes
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus

Specialties & Treatments

Treatment & Services

  • Epiretinal Membrane Surgery
  • Fluorescein Angiography
  • Intravitreal Injections For Retinal Disease
  • Laser For Diabetic Retinopathy
  • Laser Retinal Surgery
  • Laser Treatment Of Retinal Disease
  • Macular Degeneration Evaluations
  • Management Of Age Related Macular Degeneration (Amd)
  • Microincision Vitrectomy Surgery
  • Ophthalmic Surgery
  • Ophthalmology
  • Optical Coherence Tomography
  • Pars Plana Vitrectomy
  • Pediatric Ophthalmology
  • Scleral Buckle
  • Surgical And Medical Treatment Of The Retina
  • Sutureless (Small Gauge) Retinal Surgery
  • Vitreoretinal Surgery
View all 18 Treatment & Services +

Specialty in Diseases & Conditions

  • Age-Related Macular Degeneration
  • Diabetic Retinopathy
  • Diseases of the Retina
  • Diseases of the Vitreous
  • Lens Dislocation
  • Macular Hole
  • Macular Pucker
  • Pediatric Retinal Detachment
  • Retinal Detachment
  • Retinal Disorders
  • Retinal Hemangioma
  • Retinal Pigment Epithelium-Choroid Complex
  • Retinal Vein Occlusion
  • Retinitis
  • Traumatic Retinal Detachment
View all 15 Specialties +


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About Jonathan Sears, MD

Jonathan Sears, MD, is Associate Professor of Ophthalmology at the Cole Eye Institute, Cleveland Clinic. He received his undergraduate education at Yale College, graduating cum laude with a BS in chemistry. He continued with medical school at Yale University School of Medicine, where he developed a novel method of screening B-cell epitopes, which was used to help develop the Lyme vaccine. He was a Resident in Ophthalmology at Yale as well, and next completed a two-year surgical fellowship at Emory University, where he developed an interest in pediatric retinal detachment and retinopathy of prematurity (ROP).

Dr. Sears' research interest is in ROP. He uses a mouse model of ROP to test the hypothesis that small-molecule activators of hypoxia-inducible factor are able to drive retinal development early in life to prevent ROP detachment.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Emory University Hospital
Vitreoretinal Fellowship
Decatur, GA USA

Residency - Yale-New Haven Hospital
New Haven, CT USA

Internship - Yale-New Haven Hospital
Internal Medicine
New Haven, CT USA

Medical Education - Yale University School of Medicine
New Haven, CT USA

Undergraduate - Yale University
New Haven, CT USA

Professional Highlights

  • AAO Achievement Award
  • The Hartwell Foundation Research Fellow
  • Matilda Zeigler Foundation Research Fellow


  • Ophthalmology

Specialty Interests

retinal detachment secondary to degenerative disorders such as myopia or trauma or diabetes, retinopathy of prematurity and other acquired vitreoretinal diseases, vitreoretinal diseases, pediatric retina

Awards & Honors

  • Distinction in Chemistry, Department of Chemistry, Yale University, 1988$0$0Cum Laude, Yale University, 1988
  • Yale Medical Student Research Fellowship, sponsored by National Institutes of Health; Howard Hughes Medical Institute, Section of Immunobiology, Yale School of Medicine, 1990-1992
  • Harold J. Lamport Prize, awarded for the most creative biomedical research by a Yale medical student, Department of Biochemistry, Yale School of Medicine, 1992
  • Yale Resident Research Prize, Department of Ophthalmology, 1995 and 1996
  • Heed Ophthalmic Fellowship, in support of clinical research, 1997
  • Emory Medical Care Fellowship, in support of basic science research, Emory University School of Medicine, 1997
  • Association of University Professors of Ophthalmology, Fellow Research Competition, Finalist, 1998
  • Clinical Teacher of the Year Award, Department of Ophthalmology, Emory University School of Medicine, 1998
  • Clinical Investigator Development Award, Cleveland Clinic, 2003
  • Best Doctors in America, 2005-2009
  • Best Doctors in Cleveland, 2005-2009
  • American Academy of Ophthalmology Achievement Award, 2007
  • Editorial Board Member Online News and Education (O.N.E.), 2007
  • Editorial Board Member British Journal of Ophthalmology
  • Best Research, Poster American Academy of Ophthalmology, 2008
  • Strathmore Who's Who 2009

Innovations & Patents

  • Stimulating angiogenesis to prevent ischemic retinopathy


  • American Academy of Ophthalmology
  • Association of Research in Vision and Ophthalmology
  • International Congress of Eye Research
  • Association of Pediatric Retinal Surgeons
  • Cleveland Ophthalmic Society
  • Heed Ophthalmic Society$0$0
Research & Publications

Research & Publications

See publications for Jonathan Sears, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 10/21/2021, Dr. Sears has reported no financial relationship with industry that is applicable to this listing. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

282 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.9 out of 5
Explains 4.9
Courtesy, Respect & Concern 4.9
Patient Rating of Doctor 4.9

60 Patient Comments

Reviewed on Aug 24, 2021

Dr. Sears analysis and care have always been excellent and instill confidence.

Reviewed on Aug 3, 2021

Great doc and all the workers I deal with are really good !

Reviewed on Aug 3, 2021

Dr. Johnathan Sears is and has been a great doctor, taking time to explain to the patient what is going on and how it is best treated. I very, very good doctor and is an excellent example of a dedicated, caring doctor representing the Cleveland Clinic.

Reviewed on Jul 22, 2021

I have been seeing Dr. Sears now for several years. I cannot say enough good about him as a doctor, and he truly is a caring and understanding person.

Reviewed on Jul 20, 2021

Never had a better doctor

Reviewed on Jul 20, 2021

I believe I am very lucky to have Dr. Jonathan Sears on my team of doctors!!!

Reviewed on Jul 13, 2021

I like that Dr. Sears knows who I am.

Reviewed on Jun 29, 2021

Dr Sears and the nurse assistant spent a lot of care and time thinking about situation and answering my questions.

Reviewed on Jun 29, 2021

Dr. Sears is amazing. Not only is he expert in his field, but he explains everything clearly and goes above and beyond to do all that he can for my seriously dysfunctional eye. Truthfully, I would travel fro anywhere to have Dr. Sears take care of my eyes.

Reviewed on Jun 29, 2021

I routinely recommend Dr. Sears.

Reviewed on Jun 15, 2021

Dr. Sears was very knowledgeable and personable. However I do not remember what he called the thing in my eyes which he explained explicitly. Need a report. My fault.

Reviewed on Jun 15, 2021

dr sears called me at home three times to see how i was, only my heart dr ever did that, it means a lot if u dont have any relatives left.

Reviewed on Jun 15, 2021

dr sears is very caring

Reviewed on Jun 10, 2021

dr Sears the best even though the waiting was endless

Reviewed on Jun 8, 2021

Dr Sears is such a caring person, even still has regrets he couldn't do more for my elderly husband..tho he certainly tried hardand we simply love and respect him

Reviewed on Jun 8, 2021

Dr Sears is wonderful. He has a great manner & is very knowledgeable.

Reviewed on May 20, 2021

Dr. Sears was extremely helpful and informative

Reviewed on May 18, 2021

Dr. Sears is fantastic, lots to do with seeing so many patients in a day ! well done !!

Reviewed on May 18, 2021

Dr s nurse excellent job

Reviewed on May 18, 2021

Dr. Sears is the best! I would recommend his 100% to friends, family and "strangers."

Reviewed on May 18, 2021

Dr. Sears is superb. Everyone in his practice are first rate.

Reviewed on May 6, 2021

I was expecting a discussion about concurrent procedures to fix problems I was having as in past appointments. this time the recommendation changed which made me uncomfortable that something changed with my condition or the doctors anticipated outcome.

Reviewed on May 6, 2021

Dr. Sears is very good and listens to what I have to say. He is also very knowlegable and I have the greatest of confidence in him.

Reviewed on May 4, 2021

best doc and staff I ever had

Reviewed on Apr 22, 2021

Dr Sears is personable, his bedside manner is exceptional he takes time to answer any questions asked of him. i felt confident having him as my doctor.

Reviewed on Apr 22, 2021

Dr Sears and staff were all of what I expected from care givers

Reviewed on Apr 22, 2021

Always a good experience with Doctor Sears

Reviewed on Apr 20, 2021

Doctor very courteous and professional. Easy to discuss my problem with him.

Reviewed on Apr 20, 2021

Doctor was professional but old school (not interested in listening to me, just in himself talking). I didn't ask some questions I wanted because I felt rushed.

Reviewed on Apr 15, 2021

Dr Sears is outstanding & a credit to the Clinic. At my age I deal & have delt with many doctors & he is one of the best, if not the best. You are lucky to have him.

Reviewed on Apr 13, 2021

dr. Sears is a wonderful doctor

Reviewed on Apr 13, 2021

wonderful doctor would highly recommend him to friends and family

Reviewed on Apr 6, 2021

Dr. Sears is always kind and attentive to my concerns. I agreed to see him because of my past interactions with him.

Reviewed on Mar 30, 2021

Dr Sears, and his staff are wonderful, as busy as they are I always feel like I am the only patient there.

Reviewed on Mar 25, 2021

Dr. Sears is a fabulous asset for the Clinic. Outstanding physician and human being..........

Reviewed on Mar 23, 2021

dr. sears staff is fantastic

Reviewed on Mar 18, 2021

Dr. Sears was very nice.

Reviewed on Mar 16, 2021

Dr. Sears is simply amazing to work with and genuinely cares about my son. This has not been an easy journey for us, but Dr. Sears has made it a great experience. He is thorough and explains things very well. My son always looks forward to our visits, and I think that's a true indication of the care even a young boy feels he's getting. He is never afraid to go see Dr. Sears!

Reviewed on Mar 16, 2021

Dr. Sears is the best

Reviewed on Mar 9, 2021

I now consider Dr. Sears my ophthalmologist. He was excellent.

Reviewed on Mar 9, 2021

Dr. Sears has a resident that came in and did a preliminary eye check and was kind and personable.

Reviewed on Feb 25, 2021

Dr. Sears is one of the best things to happen to our child.

Reviewed on Feb 23, 2021

Dr. Sears is very caring and concerned about my family and me.We never feel like he is rushing our appointments!

Reviewed on Feb 23, 2021

I already recommend Dr. Sears and the Cole Eye Clinic. You guys saved my sight.

Reviewed on Feb 9, 2021

I have repeatedly recommended Dr. Sears to others.

Reviewed on Feb 2, 2021

Dr Mendell and Dr Sears were wonderful.... thorough, professional, and simply the best!!

Reviewed on Jan 21, 2021

great doctor and nurse

Reviewed on Jan 21, 2021

excellent capable staff and doctor

Reviewed on Jan 21, 2021

Dr. Sears is a very trusted doctor. His attention to detail and his concern is outstanding. He is someone I admire and is an example of the character and the integrity of the CCF. Hats off to him.

Reviewed on Jan 21, 2021

Kudos to Dr. Sears !!

Reviewed on Jan 12, 2021

Dr. Jonathan Sears has never disappointed me. He takes time to discuss my eye condition and his concern is evident.

Reviewed on Jan 12, 2021

was very worried about an eye injury before appointment. Dr. Sears explained the situation so I could understand it and not worry.

Reviewed on Jan 12, 2021

Dr. Sears is the best doctor in the world as far as I am concerned. I have been able to have a normal life after he operated on my serious eye problems.

Reviewed on Jan 5, 2021

great doctors!!!

Reviewed on Dec 8, 2020

*Dr. Sears is very knowledgeable and treats me with respect.

Reviewed on Dec 8, 2020

Dr. Sears, as well as the fellow, was very thorough and explained things well.

Reviewed on Dec 3, 2020

Dr. Sears is the best. No question.

Reviewed on Nov 19, 2020

I made a mistake and arrived to my appointment on the wrong day. However, the office and Dr. Sears were able to make time for me. I had driven from Buffalo, NY. I appreciated that very much!

Reviewed on Oct 29, 2020

very renowned provider

Reviewed on Oct 22, 2020

Dr. Jonathon Sears is not only a skilled surgeon, but he has an exceptional rapport with, I am certain, all of his patients!!! At all times, with many follow-up visits, I not only was attended by a man with true love for humanity and the joy of healing and improving quality of life, I MADE A FRIEND!!!! My confidence in his skill and ability is in my high esteem!!! I am a retired educator, 50 years experience!!! At this point I know a gifted, talented caring person when I work with him!!!!

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