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Patrick Byrne, MD, MBA

Patrick Byrne, MD, MBA
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Title Chair, Head & Neck Institute
Department Head and Neck Institute
Primary Location Cleveland Clinic Main Campus
Type of Doctor Both Adults and Children & Adolescents
Languages English
Surgeon Yes
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus

Specialties & Treatments

Treatment & Services

  • Adult Facial Plastic Surgery
  • Blepharoplasty
  • Botulinum Toxin Administration for Hemifacial Spasm
  • Botulinum Toxin Injections
  • Brow Lift
  • Cancer Center
  • Cheek Lift
  • Cleft Lip and Palate Surgery
  • Cosmetic Surgery of the Face
  • Ear Deformity
  • Ear Pinning/otoplasty
  • Ear Reconstruction
  • Endoscopic Cosmetic Surgery
  • EyeLid and Brow Lifts
  • Eyelid And Oculoplastic Surgery
  • Eyelid Deformity
  • Facelift (Rhytidectomy)
  • Facial Fracture Repair
  • Facial Fractures
  • Facial Implants
  • Facial Reanimation
  • Facial Reconstruction
  • Facial Rejuvenation
  • Facial Surgery
  • Facial Treatments
  • Gracilis Free Tissue Transfer
  • Head and neck reconstructive surgery
  • Injectables And Fillers For Facial Rejuvenation
  • Jaw Reconstruction
  • Lip Enhancement
  • Microvascular Reconstruction
  • Microvascular Surgery
  • Nasal Reconstruction
  • Nasal Valve Surgery
  • Neck Lift
  • Nerve Transfers For Injury/tumor
  • Otoplasty (Ear Reshaping)
  • Pediatric Facial Plastic Surgery
  • Reconstructive Head And Neck Surgery
  • Reconstructive Surgery of the Face
  • Rhinoplasty
  • Rhinoplasty Revision
  • Skin Cancer Reconstruction
View all 43 Treatment & Services +

Specialty in Diseases & Conditions

  • Basal Cell Carcinoma
  • Cleft Lip
  • Cleft Palate
  • Congenital Defects
  • Congenital Deviated Nasal Septum
  • Deviated Septum and Nasal Obstruction
  • Facial Nerve Disorders
  • Facial Nerve Paralysis
  • Facial Trauma
  • Melanoma
  • Nasal Fractures
  • Nasal Obstruction
  • Nasal Valve Collapse
  • Nose Deformity
  • Skin Cancer
  • Squamous Cell Carcinoma
View all 16 Specialties +


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About Patrick Byrne, MD, MBA

Dr. Patrick Byrne is the Chairman of Cleveland Clinic’s Head & Neck Institute, which comprises the specialties of Otolaryngology-Head and Neck Surgery, Oral and Maxillofacial Surgery and Dentistry, Audiology, and Speech and Language Sciences.

Dr. Byrne practiced at The Johns Hopkins Hospital from 2001-2020. There, he served as Director of the Division of Facial Plastic and Reconstructive Surgery in the Department of Otolaryngology/Head and Neck Surgery. He also was Professor of Otolaryngology/Head and Neck Surgery, Dermatology and Biomedical Engineering at the Johns Hopkins University School of Medicine, Director of the Johns Hopkins Facial Plastic and Reconstructive Surgery Fellowship program, Co-Director of the Johns Hopkins Face Transplant Team, and Co-Director of the Greater Baltimore Cleft Lip and Palate Team. Dr. Byrne was recruited via an extensive search to serve as Medical Director of one of the nation's largest and most complex ambulatory surgery center (ASC) initiatives while at Johns Hopkins. In this role, he led the planning, recruitment and subsequent operations of a 35,000-square-foot, newly constructed 9-room ASC to serve more than 100 different surgeons in 15 different specialties, both adult and pediatric.

A renowned facial plastic and reconstructive surgeon, Dr. Byrne specializes in complex reconstructive surgery of the face, head and neck, including microsurgical reconstruction. He has vast experience in facial aesthetic surgery, including rhinoplasty, revision rhinoplasty and facelift surgery. Rhinoplasty has been a passion for Dr. Byrne throughout his career and he had one of the highest volume practices on the East Coast prior to joining Cleveland Clinic.

He is internationally renowned for his groundbreaking work treating patients with facial paralysis. Dr. Byrne is viewed worldwide as one of the most respected surgeons for his experience performing complex facial reanimation surgery in both adults and children. Dr. Byrne believes that his two-decade focus on facial aesthetic surgery and cosmetic treatments is exceedingly beneficial for his facial paralysis patients of all ages. 

His clinical and research interests focus on facial reanimation, facial deformities, skin cancer surgery and reconstruction, as well as facial aesthetic surgery. His focus in facial aesthetic surgery is a key adjunct to his reanimation work, and includes a vast clinical experience in rhinoplasty, revision rhinoplasty, and facelifts. An active researcher, his innovative investigational work on facial paralysis treatment, skin cancer reconstruction, facial reconstruction, and related topics has been published in more than 100 peer-reviewed journal articles.

Dr. Byrne is very involved in international and humanitarian work. He served as a Johns Hopkins International Medical Director for over 10 years, assisting with the achievement of Joint Commission International accreditation for medical centers in Central America and Asia.  Dr. Byrne has traveled overseas his entire career, teaching, and leading teams performing volunteer surgery and providing medical relief to those in need in developing countries around the world. He led a sustained multiyear effort with nonprofit organizations to develop a comprehensive multidisciplinary free program dedicated to the treatment of cleft lip, cleft palate and other facial deformities for children in Nicaragua and other developing countries.

A holder of U.S. patents,  Dr. Byrne has worked in conjunction with basic science researchers to develop a novel regenerative biomaterial, funded by the Department of Defense, which recently completed a Phase II FDA trial. Dr. Byrne also developed a surgical device that assists surgeons working with cartilage, shortening operating room (OR) time and safeguarding this tissue by preventing its entry into the cutting apparatus. He also invented an FDA Class 1 medical device to aid in nasal breathing that recently completed a first-of-its-kind human clinical trial followed by a successful Series A round of funding.

Dr. Byrne earned his M.D. from the University of California San Diego School of Medicine. He completed a surgical internship at the University of California in San Francisco and a residency in Otolaryngology/Head and Neck Surgery at the University of California San Diego. He was a research fellow at the San Diego Cancer Center at the University of California followed by a fellowship in facial plastic and reconstructive surgery at the University of Minnesota. Additionally, Dr. Byrne completed a fellowship in Health Care Management at the Advisory Board Company. In 2015, he earned a Master’s degree in Business Administration from the Wharton School of The University of Pennsylvania.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Graduate School - The Wharton School of the University of Pennsylvania
Philadelphia, PA USA

Fellowship - University of Minnesota
Facial Plastic and Reconstructive Surgery
Minneapolis, MN USA

Residency - University of California at San Diego School of Medicine
Otolaryngology/Head and Neck Surgery
LaJolla, CA USA

Internship - UCSF/Mount Zion Hospital & Medical Center
General Surgery
San Francisco, CA USA

Medical Education - UC San Diego School of Medicine
La Jolla, CA USA

Undergraduate - California Lutheran University
Thousand Oaks, CA USA


  • Otolaryngology - Head and Neck Surgery
  • Facial Plastic and Reconstructive Surgery
Research & Publications

Research & Publications

See publications for Patrick Byrne, MD, MBA.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 1/3/2023, Dr. Byrne has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Equity Dr. Byrne owns stock or stock options in the following companies for activities as a founder, inventor, discover, developer:

  • BD Healthcare Ventures, LLC

Fiduciary Role. Dr. Byrne serves in a fiduciary capacity, such as an elected officer, director or chief medical officer, for the following companies or other entities:

  • Aegeria Soft Tissue LLC

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

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