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Hassan Khouli, MD

Hassan Khouli, MD
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Title Chair, Department of Critical Care Medicine
Department Critical Care Medicine
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages Arabic, English
Surgeon No
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus

Specialties & Treatments

Specialty in Diseases & Conditions

  • Acute Kidney Injury
  • Acute Respiratory Distress Syndrome (ARDS)
  • Sepsis
View all 3 Specialties +


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About Hassan Khouli, MD

Dr. Khouli is the Chair of the Department of Critical Care Medicine at the Cleveland Clinic. He has over 20 years of experience working in critical care medicine and pulmonary medicine. Dr. Khouli has special expertise in the evaluation and management of patients with complex critical illnesses including sepsis and septic shock, ARDS, multi-organ failure, and decision making at the end of life.

Prior to joining the Cleveland Clinic at the end of 2017, Dr. Khouli was a Professor of Medicine at the Icahn School of Medicine at Mount Sinai in New York, the Chief of the Critical Care Division at Mt. Sinai St. Luke’s and Mount Sinai West Hospitals, and the Chair of Medical Ethics for over 15 years. He is the 2017 recipient of the “Dr. Nathan Kase Innovations in Medical Education Award” from the Icahn School of Medicine at Mount Sinai. Dr. Khouli was an early leader in the development of simulation training and he founded the Center for Advanced Medical Simulation (CAMS) at Mount Sinai West and Mount Sinai St. Luke’s Hospitals; one of the earliest centers in the U.S. to be accredited by the Society for Simulation in Healthcare.

Dr. Khouli has been an invited lecturer regionally, nationally, and internationally. He has received several government, private foundations, and industry research grants and has authored many peer-reviewed articles, abstracts, and book chapters.

Dr. Khouli has been actively involved in public policy, including current service on the New York State Governor’s Task Force on Life and the Law (composed of individuals representing medicine, law, religion, philosophy, and bioethics), and the New York State Department of Health Sepsis Advisory Board. He has been elected to “Best Doctor in America” several years.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Mount Sinai -St. Lukes-Roosevelt
Pulmonary Medicine
New York, NY

Fellowship - Harbor Hospital Center
Non-Accredited Interventional Pulmonology
Baltimore, MD

Fellowship - Cooper Hospital/University Medical Center (UMDNJ)
Critical Care Medicine
Camden, NJ

Residency - Atlanticare Regional Medical Center
Internal Medicine
Atlantic City, NJ United States

Medical Education - Damascus University
Damascus, Syria,


  • Internal Medicine - Critical Care Medicine
  • Internal Medicine - Pulmonary Disease

Specialty Interests

Dr. Khouli has special expertise in the evaluation and management of patients with complex critical illnesses including sepsis and septic shock, ARDS, multi-organ failure, medical ethics and decision making at the end of life, medical education and training, outcome research.

Awards & Honors

Research & Publications

Research & Publications

See publications for Hassan Khouli, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 3/12/2024, Dr. Khouli has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

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