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Per Wierup, MD, PhD

Per Wierup, MD, PhD
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Department Thoracic and Cardiovascular Surgery
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages Danish, English, French, German, Swedish
Surgeon Yes
Locations Specialties & Treatments

Treatment & Services

  • Adult Cardiothoracic Surgery
  • Aorta Surgery
  • Aortic Valve Repair
  • Aortic Valve Replacement
  • Aortic Valve Surgery
  • Bypass Surgery
  • Bypass Surgery Re-operation
  • Cardiac Surgery
  • Cardiovascular Surgery Department
  • Cardiovascular Surgery Section
  • Congenital Cardiac Surgery
  • Heart Surgery
  • Heart Valve Replacement
  • Heart Valve Surgery
  • Infective Endocarditis Surgery
  • Minimally Invasive Cardiac Surgery
  • Minimally Invasive Cardiovascular Surgeries
  • Minimally Invasive Heart Surgery
  • Minimally Invasive Mitral Valve Repair
  • Minimally Invasive Surgery
  • Mitral Valve Repair
  • Mitral Valve Replacement
  • Mitral Valve Surgery
  • Modified David's Reimplantation Procedure
  • Myectomy
  • Removal of Atrial Myxoma
  • Removal of Cardiac Tumors
  • Robotic Cardiac Surgery
  • Robotic Surgery
  • Robotically Assisted Atrial Septal Defect Repair
  • Robotically Assisted Heart Surgery
  • Robotically Assisted Mitral Valve Repair
  • Robotically Assisted Removal of Cardiac Tumors
  • Robotically Assisted Tricuspid Valve Repair
  • Surgical Procedures for Atrial Fibrillation
  • Surgical Treatment of Adult Acquired Heart Disease
  • Surgical Treatment of Valve Endocarditis
  • Thoracic Aortic Aneurysm Surgery
View all 38 Treatment & Services +

Specialty in Diseases & Conditions

  • Acquired Adult Cardiac Disease
  • Acquired Valve Disease
  • Adult Congenital Heart Disease
  • Aortic Insufficiency
  • Aortic Valve Disease
  • Cardiomyopathy
  • Congenital Disorders of the Heart
  • Congenital Heart Defects
  • Heart Valve Infections
  • Infective Endocarditis
  • Mitral Valve Disease
  • Mitral Valve Prolapse
  • Mitral Valve Regurgitation
View all 13 Specialties +
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Biography

About Per Wierup, MD, PhD

Per Wierup, MD, is a heart surgeon in the Department of Cardiovascular Surgery, Sydell and Arnold Miller Family Heart, Vascular & Thoracic Institute. He sees patients at Cleveland Clinic Main Campus.

Dr. Wierup performed advanced training in cardiac surgery at Cleveland Clinic in 1998-1999, after which he returned to Europe. Over the ensuing two decades, he became internationally recognized as one of Europe’s pre-eminent cardiac surgeons. Cleveland Clinic recruited him to return to North America because of his tremendous expertise in heart valve surgery, minimally invasive surgery, and complex cardiac surgery.

Specialty Interests: Heart valve surgery, including mitral valve repair, robotic mitral valve surgery, aortic valve repair and replacement, tricuspid valve repair (Cone repair), endocarditis; aortic aneurysm repair, including aortic root reconstruction and valve-sparing aortic root replacement with the David procedure; Maze III procedure for atrial fibrillation; myectomy and surgery to relieve left-ventricular outflow tract obstruction

Number of Patients Treated: Cleveland Clinic performs more than 4,000 heart surgeries each year. All Cleveland Clinic cardiac surgeons complete between 300-400 cardiac cases per year. Dr. Wierup joined Cleveland Clinic from the Scandinavia region I Europe where he was a senior consultant in cardiovascular surgery at several different hospitals since 2000. During his career, he has focused primarily on complex cardiac reconstructions in adult patients and congenital heart surgery in children and adults.

Cleveland Clinic heart surgeons annually perform more than 6000 operations at Cleveland Clinic Main Campus, and 25 percent of them are complex re-operations

Success Rates: The overall mortality rate for patients who have heart surgery at Cleveland Clinic typically is lower than expected, compared to data from the National Society of Thoracic Surgeons. For detailed outcomes and quality information about heart procedures performed at Cleveland Clinic, go to https://my.clevelandclinic.org/departments/heart/about/outcomes-stats/outcomes-by-specialty/surgical

Education and Training:  Dr. Wierup earned his medical degree and a PhD in cardiothoracic surgery with a specialty in lung transplantation from Lund University, Lund, Sweden. He served his residency in general surgery and anesthesia at Kristianstad Hospital, Karlshamn, Sweden, and a residency in cardiothoracic surgery at University Hospital, Lund, Sweden. Dr. Wierup completed his subspecialty training as a fellow in the Department of Thoracic and Cardiovascular Surgery at Cleveland Clinic 1998-1999. 

Publications and Speaking: Dr. Wierup has published nearly 60 papers in medical journals related to patient outcomes following complex cardiac surgery, valve repair and lung transplantation. He also has been a frequent invited speaker at medical conferences in Europe and the United States.

About Dr. Wierup: “I enjoy cardiac surgery since it gives me an outstanding opportunity to make a real difference for my patients. My greatest strengths are a well-developed three-dimensional-sense of the cardiac structures and their possible reconstructions, a broad experience in both adult and congenital surgery, together with an extensive experience in cardiac reoperations and minimally invasive techniques.”

Leisure Activities: In his leisure time, Dr. Wierup enjoys piano, show jumping, Alpine skiing and spending time with his wife and three children.

Education & Professional Highlights

Education & Professional Highlights

Appointed
2025

Education & Fellowships

Graduate School - Lund University / Malmo University
Malmo, Sweden,
2002

Fellowship - Cleveland Clinic
Cardiothoracic Surgery
Cleveland, OH
1999

Residency - Lund University
Cardiothoracic Surgery
Lund, Sweden
1999

Residency - Karlshamn Hospital
General Surgery & Anesthesia
Karlshamn, Sweden
1994

Internship - Sahlgrenska University Hospital
Neurosurgery/Anesthesia/Psychiatry/Surgery
Gothenberg,
1992

Medical Education - Lund University / Malmo University
Malmo, Sweden, SW
1990

Certifications

  • Cardiothoracic Surgery

Specialty Interests

Heart valve surgery, including mitral valve repair, robotic mitral valve surgery, aortic valve repair and replacement, tricuspid valve repair (Cone repair), endocarditis; aortic aneurysm repair, including aortic root reconstruction and valve-sparing aortic root replacement with the David procedure; Maze III procedure for atrial fibrillation; myectomy and surgery to relieve left-ventricular outflow tract obstruction

Research & Publications

Research & Publications

See publications for Per Wierup, MD, PhD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 3/18/2020, Dr. Wierup has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Consulting and/or Speaking. Dr. Wierup receives fees of $5,000 or more per year (or, in rare cases, equity or stock options) as a paid consultant, speaker or as a member of an advisory committee for the following companies:

  • Medtronic ATS Medical, Inc.
  • CryoLife, Inc.
  • Edwards Lifesciences LLC

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

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