Department Thoracic and Cardiovascular Surgery
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages Danish, English, French, German, Swedish
Surgeon Yes
Locations Specialties & Treatments

Treatment & Services

  • Adult Cardiothoracic Surgery
  • Adult Congenital Heart Disease, Surgery
  • Adult Congenital Heart Surgery
  • Aorta Surgery
  • Aortic Valve Repair
  • Aortic Valve Replacement
  • Aortic Valve Surgery
  • Bypass Surgery
  • Bypass Surgery Re-operation
  • Cardiac Surgery
  • Cardiovascular Surgery Department
  • Congenital Cardiac Surgery
  • Heart Surgery
  • Heart Valve Repair and Replacement
  • Heart Valve Surgery
  • High Risk Reoperation Surgery
  • Infective Endocarditis Surgery
  • Minimally Invasive Cardiac Surgery
  • Minimally Invasive Cardiovascular Surgeries
  • Minimally Invasive Heart Surgery
  • Minimally Invasive Mitral Valve Repair
  • Minimally Invasive Surgery
  • Mitral Valve Repair
  • Mitral Valve Replacement
  • Mitral Valve Surgery
  • Modified David's Reimplantation Procedure
  • Myectomy
  • Removal of Atrial Myxoma
  • Removal of Cardiac Tumors
  • Robotic Cardiac Surgery
  • Robotic Surgery
  • Robotically Assisted Atrial Septal Defect Repair
  • Robotically Assisted Heart Surgery
  • Robotically Assisted Mitral Valve Repair
  • Robotically Assisted Patent Foramen Ovale Repair
  • Robotically Assisted Removal of Cardiac Tumors
  • Robotically Assisted Tricuspid Valve Repair
  • Surgery for Infective Endocarditis
  • Surgery for Thoracic Aortic Aneurysm
  • Surgical Procedures for Atrial Fibrillation
  • Surgical Treatment Of Adult Acquired Heart Disease
  • Surgical Treatment Of Thoracic And Cardiovascular Disease
  • Surgical Treatment Of Valve Endocarditis
  • Thoracic and Cardiovascular Surgery Section
View all 44 Treatment & Services +

Specialty in Diseases & Conditions

  • Acquired Adult Cardiac Disease
  • Acquired Valve Disease
  • Adult Congenital Heart Disease
  • Aortic Insufficiency
  • Aortic Valve Disease
  • Cardiomyopathy
  • Congenital Disorders of the Heart
  • Congenital Heart Defects
  • Heart Valve Infections
  • Infective Endocarditis
  • Mitral Valve Disease
  • Mitral Valve Prolapse
  • Mitral Valve Regurgitation
View all 13 Specialties +


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About Per Wierup, MD, PhD

Per Wierup, MD, is a heart surgeon in the Department of Cardiovascular Surgery, Sydell and Arnold Miller Family Heart, Vascular & Thoracic Institute. He sees patients at Cleveland Clinic Main Campus.

Dr. Wierup performed advanced training in cardiac surgery at Cleveland Clinic in 1998-1999, after which he returned to Europe. Over the ensuing two decades, he became internationally recognized as one of Europe’s pre-eminent cardiac surgeons. Cleveland Clinic recruited him to return to North America because of his tremendous expertise in heart valve surgery, minimally invasive surgery, and complex cardiac surgery.

Specialty Interests: Heart valve surgery, including mitral valve repair, robotic mitral valve surgery, aortic valve repair and replacement, tricuspid valve repair (Cone repair), endocarditis; aortic aneurysm repair, including aortic root reconstruction and valve-sparing aortic root replacement with the David procedure; Maze III procedure for atrial fibrillation; myectomy and surgery to relieve left-ventricular outflow tract obstruction

Number of Patients Treated: Cleveland Clinic performs more than 4,000 heart surgeries each year. All Cleveland Clinic cardiac surgeons complete between 300-400 cardiac cases per year. Dr. Wierup joined Cleveland Clinic from the Scandinavia region I Europe where he was a senior consultant in cardiovascular surgery at several different hospitals since 2000. During his career, he has focused primarily on complex cardiac reconstructions in adult patients and congenital heart surgery in children and adults.

Cleveland Clinic heart surgeons annually perform more than 6000 operations at Cleveland Clinic Main Campus, and 25 percent of them are complex re-operations

Success Rates: The overall mortality rate for patients who have heart surgery at Cleveland Clinic typically is lower than expected, compared to data from the National Society of Thoracic Surgeons. For detailed outcomes and quality information about heart procedures performed at Cleveland Clinic, go to

Education and Training:  Dr. Wierup earned his medical degree and a PhD in cardiothoracic surgery with a specialty in lung transplantation from Lund University, Lund, Sweden. He served his residency in general surgery and anesthesia at Kristianstad Hospital, Karlshamm, Sweden, and a residency in cardiothoracic surgery at University Hospital, Lund, Sweden. Dr. Wierup completed his subspecialty training as a fellow in the Department of Thoracic and Cardiovascular Surgery at Cleveland Clinic 1998-1999. He was named to the Cleveland Clinic staff in 2017.

Publications and Speaking: Dr. Wierup has published nearly 60 papers in medical journals related to patient outcomes following complex cardiac surgery, valve repair and lung transplantation. He also has been a frequent invited speaker at medical conferences in Europe and the United States.

About Dr. Wierup: “I enjoy cardiac surgery since it gives me an outstanding opportunity to make a real difference for my patients. My greatest strengths are a well-developed three-dimensional-sense of the cardiac structures and their possible reconstructions, a broad experience in both adult and congenital surgery, together with an extensive experience in cardiac reoperations and minimally invasive techniques.”

Leisure Activities: In his leisure time, Dr. Wierup enjoys piano, show jumping, Alpine skiing and spending time with his wife and three children.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Graduate School - Lund University / Malmo University
Malmo, Sweden, SW

Residency - Lund University
Cardiothoracic Surgery
Lund, Sweden

Fellowship - Cleveland Clinic
Cardiothoracic Surgery
Cleveland, OH USA

Internship - Sahlgrenska University Hospital

Medical Education - Lund University / Malmo University
Malmo, Sweden, SW


  • Cardiothoracic Surgery

Specialty Interests

Heart valve surgery, including mitral valve repair, robotic mitral valve surgery, aortic valve repair and replacement, tricuspid valve repair (Cone repair), endocarditis; aortic aneurysm repair, including aortic root reconstruction and valve-sparing aortic root replacement with the David procedure; Maze III procedure for atrial fibrillation; myectomy and surgery to relieve left-ventricular outflow tract obstruction

Research & Publications

Research & Publications

See publications for Per Wierup, MD, PhD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 3/18/2020, Dr. Wierup has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Consulting and/or Speaking. Dr. Wierup receives fees of $5,000 or more per year as a paid consultant, speaker or member of an advisory committee for the following companies:

  • Edwards Lifesciences LLC
  • CryoLife, Inc.
  • Medtronic ATS Medical, Inc.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

111 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.8 out of 5
Explains 4.8
Listens 4.9
Courtesy, Respect & Concern 4.9
Patient Rating of Doctor 4.9

9 Patient Comments

Reviewed on Dec 2, 2020

All physicians were excellent! *Dr. Wierup was phenomenal!

Reviewed on Sep 28, 2020

Everything was so well coordinated as we do not live in CLE. My surgeon *Dr. Wierup was so kind, and I felt so confident that he would take good care of me.

Reviewed on Jul 28, 2020

*Dr. Wierup and the NPs working with him were great (*Jackie, *Andy).

Reviewed on Jul 28, 2020

My surgeon, *Dr. Weirup came in twice to check on me.

Reviewed on Jul 18, 2020

When I saw physician staff, they were excellent & very reassuring.

Reviewed on Jun 25, 2020

Dr Wierup did a wonderful Job of taking the time to explain to me the reasons for OHS versus possible TAVR. Going over the pro and cons of both as they applied to my case. I feel very fortunate to have discovered such a talented Surgeon

Reviewed on Jun 15, 2020

*Dr. Wierup is the best. All the doctors were amazing. Very kind and spent good time with me.

Reviewed on Mar 27, 2020

Dr. Wierup was excellent! From my general appointment with him all the way through surgery. He was very personable and aided greatly in easing the anxiety that I was having about surgery.

Reviewed on Jan 20, 2020

Very good communication. Doctors gave all the time we wished for to answer questions and to follow up.

Related Videos Featuring Per Wierup, MD, PhD

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