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Samuel Irefin, MD

Samuel Irefin, MD
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Department General Anesthesiology
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English
Surgeon Yes


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About Samuel Irefin, MD

Samuel A. Irefin, MD, is a Staff Physician in the Anesthesiology Institute at Cleveland Clinic. He is also a Staff Physician in the Transplant Center of the Division of Surgery. 

Dr. Irefin has various roles that help foster medical education. He is an Associate Professor at the Cleveland Clinic Lerner College of Medicine, Director of Undergraduate Medical Education in the Anesthesiology Institute and Director of Advanced Core Curriculum in Perioperative Medicine and Pain at the Cleveland Clinic Lerner College of Medicine. Dr. Irefin was also an Assistant Professor at the Cleveland Health Sciences Center of The Ohio State University in Columbus, Ohio, from July 1999-June 2004.

Currently, he is a Diplomate of the National Board of Medical Examiners, Diplomate of the American Board of Anesthesiology and Fellow of the American College of Critical Care Medicine. He is certified by the American Board of Anesthesiology in anesthesiology and critical care medicine.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Cleveland Clinic
Critical Care
Cleveland, OH USA

Residency - Cleveland Clinic
Cleveland, OH USA

Residency - Medical College of Wisconsin
General Surgery
Milwaukee, WI USA

Internship - Medical College of Wisconsin
General Surgery
Milwaukee, WI USA

Internship - Good Samaritan Hospital & Health Center
Cincinnati, OH USA

Medical Education - Saint Louis University School of Medicine
St. Louis, MO USA

Graduate School - Western Kentucky University
Bowling Green, KY USA

Undergraduate - Western Kentucky University
Bowling Green, KY USA


  • Anesthesiology - Critical Care Medicine
  • Anesthesiology

Specialty Interests

acute postoperative pain management, ambulatory anesthesia, anesthesia for bariatric surgery, anesthesia for complicated cardiovascular, anesthesia for ENT and endotracheal and bronchial surgery, anesthesia for ENT surgery, anesthesia for interventional pulmonology, anesthesia for lithotripsy, anesthesia for liver transplantation, anesthesia for major abdominal and vascular surgery, anesthesia for obstetrics, anesthesia for orthopedic surgery, anesthesia for patients with difficult airways, anesthesia for transplant procedures, anesthesia for urological surgery, anesthesia for vascular surgery, anesthesia recovery, blood conservation, blood substitutes, brain protection, clinical pharmacology, clinical research, clinical research on perioperative inflammation, critical care, critical care education, critical care medicine, difficult airway, difficult airway management, education, education in anesthesia, education in anesthesiology, electrophysiologic monitoring, ENT anesthesia, fiberoptic intubation, general and ambulatory anesthesia, general and vascular anesthesiology, general anesthesia, genitourinary and gynecologic anesthesia, genitourinary anesthesia, graduate/medical student education, hepatic transplantation anesthesia, high-frequency jet ventilation, Infectious Diseases, jet ventilation, liver transplantation, malignant hyperthermia, metabolic derangements, MIS anesthesia, neuroanesthesia, neuroanesthesiology, neurological critical care, neurophysiological monitoring, neurosurgical anesthesiology, obstetric anesthesia, obstetric anesthesiology, office-based anesthesia, operating room management, ophthalmic anesthesia, orthopaedic anesthesia, outcomes in critical care patients, outpatient anesthesia, patient safety, patient simulation, perioperative anesthesia evaluation, perioperative management, perioperative medicine, physician teaching and training, preoperative assessment, preoperative evaluation, regional anesthesia, regional anesthesia and research, regional anesthesiology, research and teaching clinical anesthesia, residency training, resident education, resident teaching, Sepsis, Shock, solid organ transplantation, Surgical critical care, ultrasound guided blocks, urologic surgery, urology & GYN, vascular anesthesia

Awards & Honors

  • Fellow, American College of Critical Care Medicine
Research & Publications

Research & Publications

See publications for Samuel Irefin, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 1/23/2024, Dr. Irefin has reported no financial relationship with industry that is applicable to this listing. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

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