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Department Hematology and Medical Oncology
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English, Hindi, Malayalam
Surgeon No
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus

Specialties & Treatments

Treatment & Services

  • Blood Tests
  • Blood Transfusion
  • Cancer Center
  • Cancer Supportive Care
  • Chemoprevention
  • Chemotherapy
  • Clinical Drug Trials
  • Clinical Trials
  • Endocrine Aspects of Cancer
  • Endocrine Treatment
  • Immunotherapy
  • Second Opinion
  • Targeted Treatment
  • Women's Health
View all 14 Treatment & Services +

Specialty in Diseases & Conditions

  • Breast Cancer
  • Breast Cancer - High Risk
  • Breast Cancer - Mass, Lump or Swelling
  • Cancer
  • Cancer Symptoms
  • Male Breast Cancer
  • Metastatic Breast Cancer
  • Metastatic Cancer
View all 8 Specialties +


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About Jame Abraham, MD

Jame Abraham, M.D., FACP, is the chairman of the Department of Hematology & Medical Oncology at Cleveland Clinic and professor of medicine at Cleveland Clinic Lerner College of Medicine. From May 2021 to July 2022, he served as interim chair of the Taussig Cancer Institute and deputy director of the Case Comprehensive Cancer Center.

Dr. Abraham was director of the Cleveland Clinic Breast Oncology Program, and co-director of the Cleveland Clinic Comprehensive Breast Cancer Program from 2013 to 2019. He has more than 20 years of experience treating complicated breast cancer diagnoses, from early stage to metastatic, and leading novel clinical trials. 

Dr. Abraham is a member of the National Comprehensive Cancer Network (NCCN) Breast Cancer Committee, which sets treatment guidelines for breast cancer management across the United States. He is the vice chair of the Research Strategy Committee of NRG Oncology, one of the largest cancer research groups in the world, funded by the National Cancer Institute (NCI). Dr. Abraham also is a member of the Breast Committee Working Group of NRG Oncology. He is the vice chair of the Research Review Committee for the National Surgical Adjuvant Breast and Bowel Project (NSABP) and a member of the Scientific Advisory Board for NSABP.

Dr. Abraham completed his residency at the University of Connecticut School of Medicine, followed by a medical oncology fellowship from the National Cancer Institute (NCI) and hematology fellowship from the National Heart, Lung, and Blood Institute of the National Institutes of Health. Dr. Abraham earned his medical degree from Calicut Medical College, Kerala, India.

At the NCI, Dr. Abraham was the study chair of several early-phase clinical trials that included novel treatments for breast cancer, such as Ixabepilone, which was approved by the FDA in 2007. During his fellowship, Dr. Abraham edited the first edition of the Bethesda Handbook of Oncology (Lippincott Williams and Wilkins). Now in its sixth edition, it is one of the best-selling oncology textbooks in the world and considered the standard textbook by many universities and hospitals. 

Dr. Abraham is deputy editor of Journal of Oncology Practice of American Society of Clinical Oncology (ASCO) and associate editor of ASCO Post.

After finishing fellowship training, Dr. Abraham joined West Virginia University (WVU) in 2001 as an assistant professor. In 2005, he was appointed chief of hematology/oncology. He also served as the first Bonnie Wells Wilson Distinguished Professor of Breast Cancer Research and a professor of medicine of WVU. Dr. Abraham established the first comprehensive breast cancer program in West Virginia in 2002. He received several awards from WVU for patient care and teaching, including “Attending of the Year” and “Teacher of the Year.” His outstanding work in patient care was recognized by the Excellence in Clinical Medicine award from the dean of the school of medicine in 2010. That year he received an award from the President of India, Her Excellency Mrs. Pratibha Patil for his contribution to cancer care.

Dr. Abraham has been involved with several national clinical trials, many of which are NSABP trials, to find better treatment options for early-stage, metastatic, triple-negative and HER-2 positive breast cancer patients. He is the North American study chairman of DESTINY 05 (NSABP B 60 trial), which is a global adjuvant breast cancer clinical trial with Trastuzumab Deruxetecan , which will enroll nearly 2,000 patients from more than 30 countries.

He has contributed more than 200 papers and presentations at national and international meetings, and has had his work published in journals such as Journal of Clinical Oncology, JAMA, JAMA Oncology and Clinical Cancer Research.

Dr. Abraham’s primary focus and passion is taking care of patients with breast cancer. 

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - National Cancer Institute
Medical Oncology
Bethesda, MD

Fellowship - National Heart, Lung and Blood Institute
Bethesda, MD

Residency - University of Connecticut
Internal Medicine
Farmington, CT

Medical Education - Calicut Medical College
Calicut, Kerala, India,

Undergraduate - Calicut Medical College
Calicut, Kerala, India,

Additional Training

  • Senior Fellow, Developmental Therapeutics, National Cancer Institute 2001
  • Leadership Development for Physicians in Academic Health Centers, School of Public Health, Harvard, Boston. 2006

Professional Highlights

  • Chairman, Cleveland Clinic Department of Hematology & Medical Oncology
  • Professor of Medicine, Cleveland Clinic Lerner College of Medicine
  • Medical Director, Community Outreach, Taussig Cancer Institute
  • Member, NCCN, Breast Cancer Committee
  • Vice Chair, Research Strategy, NRG Oncology
  • Co-Director, Cleveland Clinic Comprehensive Breast Cancer Program (2013-2019)
  • Member, Breast Cancer Working Committee, NRG Oncology (2019- 2022)
  • Member, Breast Cancer Committee, NRG Oncology (2015-Present)   
  • Member, Translational Research Committee, NRG Oncology (2015-18)
  • Co-Principal Investigator, Leading Academic Participating Sites (LAPS), National Cancer Institute  grant for the Case Comprehensive Cancer Center (2014-2017)
  • Principal Investigator of NSABP for Cleveland Clinic (2013 to present)
  • Vice Chair, Research Review Committee, NSABP Foundation (2013-Present)
  • Member of Breast Cancer Working Group, NSABP (2010-2013)
  • Founding Editor of Bethesda Handbook of Clinical Oncology, Wolter Kluwer, Philadelphia (5th edition)
  • Chief Editor, Emerging Cancer Therapeutics, Demos, New York
  • Editor, Community and Supportive Care Oncology (Frontline Communications, NJ)
  • Editor, Breast Cancer Management and Treatment (London, U.K)
  • Associate Editor and Guest Editor, ASCO Post (Harborside Press, NY)
  • Board of Directors, American Cancer Society, South Atlantic Division (2007-2010)
      • Editorial Board Member:
        • Journal of Breast Cancer Management, Future Science Group, London, U.K, Oncology and Biotechnology News, New Jersey, Expert Review of Anticancer Therapy, Future Science Group, London, U.K.
      • Manuscript Reviewer:
        • Lancet Oncology, Lancet
        • Journal of Clinical Oncology, ASCO
        • Clinical Cancer Research Focus, AACR
        • Human Bain Mapping
        • Expert Review of Immunotherapy
        • Clinical Breast Disease
        • British Journal of Cancer, Nature Publications Group
        • Annals of Saudi Medicine
        • Clinical Cancer Research, AACR
        • Expert Review of Anticancer Therapy
        • Cancer: American Cancer Society
        • Cancer Chemotherapy and Pharmacology


  • Internal Medicine - Medical Oncology

Specialty Interests

Breast Cancer treatment, Clinical Trials

Awards & Honors

  • Teacher of the Year Award: Oncology, Taussig Cancer Institute, Cleveland Clinic, 2016
  • Top Doctors in Cleveland 2014, 2015, 2016, 2017, 2018 -  Cleveland Magazine
  • Top Cancer Doctors in U.S, Newsweek, 2015
  • U.S. News Top Doctor, Castle Connolly Medical Ltd, 2010 to 2018  
  • Selected to the Gold Human Honor Society (GHHS), 2011
  • “Pink Tie Guy” – Selected by Susan G. Komen for the Cure, WV 2010
  • Dean’s Award for Excellence in Clinical Medicine, School of Medicine, West Virginia University, 2010
  • Quality Award (Customer Satisfaction), West Virginia University Hospitals, 2006-2013
  • President of India, Her Excellency, Smt. Pratibha Patil “Vaidya Bhooshan”, by the Pazhassi Raja Trust, New Delhi, India, 2010
  • Bonnie Wells Wilson Eminent Scholar and Distinguished Professor in Breast Cancer Research, 2009
  • Outstanding Achievement in Medicine, Kerala Center, India League, New York, 2008
  • Outstanding Faculty Award, Department of Medicine, West Virginia University, 2007
  • STAR Award for customer service, West Virginia University Hospital, 2006
  • Clinician of the Year Award, Department of Medicine, West Virginia University, 2006
  • Volunteer of the Year Award for the state of West Virginia, American Cancer Society (ACS) 2006

Innovations & Patents

    1. Population Based Molecular Prognosis of Breast Cancer by Transcriptional Profiling by 28 Gene Assay, 2007 (Provisional Serial Number: 60/919,369
    2. Nonlinear Characterization of Breast Cancer using Multi-Compression 3D Ultrasound Elastography (Patent pending) Nonlinear Characterization of Breast Cancer using Multi-Compression 3D Ultrasound Elastography (Patent pending)


  • American Society of Clinical Oncology (ASCO)
  • American College of Physicians (ACP)
  • American Association of Cancer Research (AACR)
Research & Publications

Research & Publications

See publications for Jame Abraham, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 5/4/2024, Dr. Abraham has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Consulting and/or Speaking. Dr. Abraham receives fees of $5,000 or more per year (or, in rare cases, equity or stock options) as a paid consultant, speaker or as a member of an advisory committee for the following companies:

  • Curio Science LLC

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

160 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
5 out of 5
Explains 5
Listens 5
Courtesy, Respect & Concern 5
Patient Rating of Doctor 5

64 Patient Comments

Reviewed on May 29, 2024

I am extremely fortunate to have Dr.Abraham as my oncologist.

Reviewed on May 15, 2024

Dr. Abraham and Nancy were both very professional but took the time to get to know me, and to discuss/explain my plan of treatment.

Reviewed on May 9, 2024

My visit with Dr. Abraham was all good!

Reviewed on Apr 15, 2024

My Dr. And his assistant go above and beyond to help me and make sure I understand all the information

Reviewed on Apr 10, 2024

Dr. Abram, and Nancy have taken such care guiding me through the last three years of cancer treatments. I am so lucky to have such great care available to me in my hometown. I will forever be grateful to them and the Cleveland Clinic.

Reviewed on Apr 3, 2024

Dr Abraham is a wonderful Doctor I come from Grafton WV and he is the best. The Doctor that came in before was wonderful too.

Reviewed on Apr 3, 2024

Wonderful Doctor

Reviewed on Apr 3, 2024

My care has always been excellent and Dr. Abraham and Nancy Dalpiaz are outstanding in responding and helping me.

Reviewed on Apr 3, 2024

I have absolute trust in Dr. Abraham and his staff.

Reviewed on Mar 27, 2024

Dr Abraham is the best! He is always responsive and addresses any concerns or questions I may have. He gives me a sense of confidence and optimism with his care. I have recommended several people to Dr Abraham.

Reviewed on Mar 20, 2024

Dr Abraham spends so much time with meand answers ALL my questions! And never cuts appointments short, always takes his time. And I recommend him to many people, all the time!

Reviewed on Mar 20, 2024

Dr. Jame Abraham is most excellent.

Reviewed on Mar 20, 2024

Top notch care from world's best providers, especially Dr. Abraham.

Reviewed on Mar 14, 2024

Dr. Abraham far exceeds the "very good" highest option in every category. Consistently.

Reviewed on Mar 14, 2024

Dr. Abraham and all his staff are stellar, especially Nancy.

Reviewed on Mar 13, 2024

Dr Abraham is a wonderful doctor and his nurse Nancy is so efficient and compassionate.

Reviewed on Mar 13, 2024

Dr Abraham is the best!

Reviewed on Mar 13, 2024

Dr abraham is one of the kindest and sincerest doctors I have ever met.

Reviewed on Mar 7, 2024

Before I SAW Dr Abraham, I was so confused and anxious about my recent cancer diagnosis.After seeing him and his associate they took the needed time to get to Know me!!! And actually explained what my diagnosis meant in TERMS I understand, and how and Why tests needed to be Done! No other Doctor had done that before!! Dr Abraham to me is a life changer! I walked out of his office for the first time in 3 weeks, with knowledge and Acceptance Thank you!!! I didn't have to Throw up like I usually do after an appointment so upset! Im finally accepting and getting surgery tomorrow with the correct facts on my cancer! Dr Abraham and his staff is amazing I'm so blessed to have him as my oncologist!

Reviewed on Mar 7, 2024

Dr. Abraham connected on a human level

Reviewed on Mar 7, 2024

Dr Abraham is awesome!

Reviewed on Feb 29, 2024

Dr. Abraham and his staff are top notched and I would never go to see anyone else!

Reviewed on Feb 21, 2024

Dr. Jame Abraham and his NP, Nancy, and the entire staff are amazing. We are almost at the end of the 2nd year of treatment and they are as attentive and professional as day 1.

Reviewed on Feb 15, 2024

Dr. Abraham is phenomenal doctor. My experience was better than five star.

Reviewed on Feb 15, 2024

Dr. Abraham changed my appointment to accommodate talking to me sooner as I had two problems spots in my PET scan. Meanwhile, almost 3 weeks have gone by and my doctor in Florida has not even called me or returned my messages. Dr. Abraham is an amazing person.

Reviewed on Jan 11, 2024

Dr Abraham was an excellent communicator as well as professional, knowledgeable and personable. I'm very thankful to be under his care.

Reviewed on Jan 10, 2024

Dr. Abraham is the kindest doctor ever. I can't say enough great things about him.

Reviewed on Jan 10, 2024

Dr. Abraham and his nurse Nancy are the best

Reviewed on Jan 10, 2024

My experience with Dr. Abraham and his office staff has been exceptional.

Reviewed on Jan 2, 2024

Dr Abraham is not only kind, empathic, knowledgeble but also master of joint decision making

Reviewed on Dec 20, 2023

Great job Dr Abraham and team!

Reviewed on Dec 13, 2023

Dr Abraham is wonderful. He is knowledgeable, compassionate, respectful.

Reviewed on Dec 13, 2023

Very happy with my care at CCF and with Dr. Abraham

Reviewed on Dec 13, 2023

He is very knowledgeable, caring Physician and a good listener. I was lucky to have him as a oncologist during Cancer treatment.

Reviewed on Nov 22, 2023

Dr Abraham and his staff are always efficient and courteous.

Reviewed on Nov 16, 2023

Dr Abraham was amazing! He sat with me and took his time to explain my treatment plan and was so caring and made me feel so comfortable. I'm so glad I went to Cleveland Clinic to see him

Reviewed on Nov 8, 2023

Dr Abraham listens to me and he makes me feel comfortable!!

Reviewed on Nov 8, 2023

He always makes feel as if I'm his only patient. He is a professional caring doctor

Reviewed on Oct 11, 2023

I highly recommend Dr. Abraham! He is an amazing doctor and such a caring person. He is very positive and calms you as you go through the scary cancer journey.

Reviewed on Oct 4, 2023

I'm proud to be a patient of Cleveland clinic for my care. Love Dr Abraham and his staff!

Reviewed on Oct 4, 2023

Working with Dr Abraham and his team has been wonderful!

Reviewed on Oct 4, 2023

Dr Abraham and his assistant Nancy have been wonderful.

Reviewed on Sep 28, 2023

Wonderful Doctor

Reviewed on Sep 27, 2023

Dr. Abraham is wonderful. He listens, is patient, very personable, really cares.

Reviewed on Sep 20, 2023

Dr. Abraham is a gifted physician. His knowledge and experience, coupled with his attentive listening, thorough explanations, warmth, caring and respectful interactions make him an extraordinary doctor.

Reviewed on Sep 20, 2023

Always referring people to Dr. Abraham and Cleveland Clinic!

Reviewed on Sep 20, 2023

Love Dr Abraham and Cleveland Clinic! I have been to alot of hospitals in the tri state area and this one is far above the rest! Thats why we make the 3 hour trek!

Reviewed on Aug 23, 2023

Dr. Jame Abraham is the best of the best; extremely caring, great listener, gentle, encouraging, and understanding.

Reviewed on Aug 10, 2023

He is one of the best Doctors I have been to. Very knowledgeable and very nice. His nurse was wonderful too. I came from West Virginia for him to be my doctor.

Reviewed on Aug 2, 2023

He is always very thorough and compassionate. I travel from out of state to see him and it's worth it to make the long trip.

Reviewed on Aug 2, 2023

I wish the wait time was shorter regarding waiting for the doctor to come in the room.

Reviewed on Aug 2, 2023

Overall a wonderful, positive experience despite personally dealing with the challenges of the disease. Would definitely highly recommend Dr. Abraham

Reviewed on Aug 2, 2023

Dr Abraham is an amazing person and doctor. His fellow was also wonderful.

Reviewed on Aug 2, 2023

Again, overall I am very pleased I chose Dr. Abraham and Cleveland Clinic. Otherwise I feel I would be on the wrong track to find the correct path forward to eliminate the cancer.

Reviewed on Aug 2, 2023

Cleveland Clinic is the bestand Dr Abraham is a blessing from God to all his patients!

Reviewed on Aug 2, 2023

Always always recommend Dr Abraham to others!

Reviewed on Jul 26, 2023

Dr Abraham is an excellent provider

Reviewed on Jul 26, 2023

Dr Abraham is the kindest most empathetic and caring physician that I have met.

Reviewed on Jul 12, 2023

Dr Abraham was amazing. His care, concern and explanations were extremely reassuring and insightful.

Reviewed on Jul 12, 2023

Very happy with care I receive from all staff I see in Dr Abraham's practiceI feel extremely safe and confident about the treatment I receive and quality of all aspects of the service delivery

Reviewed on Jul 12, 2023

Dr Abraham is fantastic

Reviewed on Jul 5, 2023

Dr Abraham went above the call to help me feel valued.

Reviewed on Jun 8, 2023

Both the resident Dr and Dr Abraham were caring, thorough, friendly and extremely knowledgeable/experienced.

Reviewed on Jun 7, 2023

Dr. Abraham is a wonderful doctor. He is sensitive, thoughtful, patient, kind, reassuring, compassionate, endearing, positive, professional. I feel very fortunate to have him as my oncologist. I always feel better after leaving his office.

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