Jame Abraham, MD
Primary Location
Cleveland Clinic Main Campus
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- 216.444.6833
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- 216.445.0150
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- 216.444.9464
Additional Locations
Treatment & Services
- Blood Tests
- Blood Transfusion
- Cancer Center
- Cancer Supportive Care
- Chemoprevention
- Chemotherapy
- Clinical Drug Trials
- Clinical Trials
- Endocrine Aspects of Cancer
- Endocrine Treatment
- Immunotherapy
- Second Opinion
- Targeted Treatment
- Women's Health
Specialty in Diseases & Conditions
- Breast Cancer
- Breast Cancer - High Risk
- Breast Cancer - Mass, Lump or Swelling
- Cancer
- Cancer Symptoms
- Male Breast Cancer
- Metastatic Breast Cancer
- Metastatic Cancer
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View All PlansAbout Jame Abraham, MD
Jame Abraham, M.D., FACP, is the chairman of the Department of Hematology & Medical Oncology at Cleveland Clinic and professor of medicine at Cleveland Clinic Lerner College of Medicine. From May 2021 to July 2022, he served as interim chair of the Taussig Cancer Institute and deputy director of the Case Comprehensive Cancer Center.
Dr. Abraham was director of the Cleveland Clinic Breast Oncology Program, and co-director of the Cleveland Clinic Comprehensive Breast Cancer Program from 2013 to 2019. He has more than 20 years of experience treating complicated breast cancer diagnoses, from early stage to metastatic, and leading novel clinical trials.
Dr. Abraham is a member of the National Comprehensive Cancer Network (NCCN) Breast Cancer Committee, which sets treatment guidelines for breast cancer management across the United States. He is the vice chair of the Research Strategy Committee of NRG Oncology, one of the largest cancer research groups in the world, funded by the National Cancer Institute (NCI). Dr. Abraham also is a member of the Breast Committee Working Group of NRG Oncology. He is the vice chair of the Research Review Committee for the National Surgical Adjuvant Breast and Bowel Project (NSABP) and a member of the Scientific Advisory Board for NSABP.
Dr. Abraham completed his residency at the University of Connecticut School of Medicine, followed by a medical oncology fellowship from the National Cancer Institute (NCI) and hematology fellowship from the National Heart, Lung, and Blood Institute of the National Institutes of Health. Dr. Abraham earned his medical degree from Calicut Medical College, Kerala, India.
At the NCI, Dr. Abraham was the study chair of several early-phase clinical trials that included novel treatments for breast cancer, such as Ixabepilone, which was approved by the FDA in 2007. During his fellowship, Dr. Abraham edited the first edition of the Bethesda Handbook of Oncology (Lippincott Williams and Wilkins). Now in its sixth edition, it is one of the best-selling oncology textbooks in the world and considered the standard textbook by many universities and hospitals.
Dr. Abraham is deputy editor of Journal of Oncology Practice of American Society of Clinical Oncology (ASCO) and associate editor of ASCO Post.
After finishing fellowship training, Dr. Abraham joined West Virginia University (WVU) in 2001 as an assistant professor. In 2005, he was appointed chief of hematology/oncology. He also served as the first Bonnie Wells Wilson Distinguished Professor of Breast Cancer Research and a professor of medicine of WVU. Dr. Abraham established the first comprehensive breast cancer program in West Virginia in 2002. He received several awards from WVU for patient care and teaching, including “Attending of the Year” and “Teacher of the Year.” His outstanding work in patient care was recognized by the Excellence in Clinical Medicine award from the dean of the school of medicine in 2010. That year he received an award from the President of India, Her Excellency Mrs. Pratibha Patil for his contribution to cancer care.
Dr. Abraham has been involved with several national clinical trials, many of which are NSABP trials, to find better treatment options for early-stage, metastatic, triple-negative and HER-2 positive breast cancer patients. He is the North American study chairman of DESTINY 05 (NSABP B 60 trial), which is a global adjuvant breast cancer clinical trial with Trastuzumab Deruxetecan , which will enroll nearly 2,000 patients from more than 30 countries.
He has contributed more than 200 papers and presentations at national and international meetings, and has had his work published in journals such as Journal of Clinical Oncology, JAMA, JAMA Oncology and Clinical Cancer Research.
Dr. Abraham’s primary focus and passion is taking care of patients with breast cancer.
Education & Professional Highlights
Appointed
2013
Education & Fellowships
Fellowship - National Cancer Institute
Medical Oncology
Bethesda,
MD United States
2001
Fellowship - National Heart, Lung and Blood Institute
Hematology
Bethesda,
MD
1999
Residency - University of Connecticut
Internal Medicine
Farmington,
CT
1997
Medical Education - Calicut Medical College
Calicut, Kerala, India,
1991
Undergraduate - Calicut Medical College
Calicut, Kerala, India,
1983
Additional Training
- Senior Fellow, Developmental Therapeutics, National Cancer Institute 2001
- Leadership Development for Physicians in Academic Health Centers, School of Public Health, Harvard, Boston. 2006
Professional Highlights
- Chairman, Cleveland Clinic Department of Hematology & Medical Oncology
- Professor of Medicine, Cleveland Clinic Lerner College of Medicine
- Medical Director, Community Outreach, Taussig Cancer Institute
- Member, NCCN, Breast Cancer Committee
- Vice Chair, Research Strategy, NRG Oncology
- Co-Director, Cleveland Clinic Comprehensive Breast Cancer Program (2013-2019)
- Member, Breast Cancer Working Committee, NRG Oncology (2019- 2022)
- Member, Breast Cancer Committee, NRG Oncology (2015-Present)
- Member, Translational Research Committee, NRG Oncology (2015-18)
- Co-Principal Investigator, Leading Academic Participating Sites (LAPS), National Cancer Institute grant for the Case Comprehensive Cancer Center (2014-2017)
- Principal Investigator of NSABP for Cleveland Clinic (2013 to present)
- Vice Chair, Research Review Committee, NSABP Foundation (2013-Present)
- Member of Breast Cancer Working Group, NSABP (2010-2013)
- Founding Editor of Bethesda Handbook of Clinical Oncology, Wolter Kluwer, Philadelphia (5th edition)
- Chief Editor, Emerging Cancer Therapeutics, Demos, New York
- Editor, Community and Supportive Care Oncology (Frontline Communications, NJ)
- Editor, Breast Cancer Management and Treatment (London, U.K)
- Associate Editor and Guest Editor, ASCO Post (Harborside Press, NY)
- Board of Directors, American Cancer Society, South Atlantic Division (2007-2010)
- Editorial Board Member:
- Journal of Breast Cancer Management, Future Science Group, London, U.K, Oncology and Biotechnology News, New Jersey, Expert Review of Anticancer Therapy, Future Science Group, London, U.K.
- Manuscript Reviewer:
- Lancet Oncology, Lancet
- Journal of Clinical Oncology, ASCO
- Clinical Cancer Research Focus, AACR
- Human Bain Mapping
- Expert Review of Immunotherapy
- Clinical Breast Disease
- British Journal of Cancer, Nature Publications Group
- Annals of Saudi Medicine
- Clinical Cancer Research, AACR
- Expert Review of Anticancer Therapy
- Cancer: American Cancer Society
- Cancer Chemotherapy and Pharmacology
- Editorial Board Member:
Certifications
- Internal Medicine - Medical Oncology
Specialty Interests
Breast Cancer treatment, Clinical Trials
Awards & Honors
- Teacher of the Year Award: Oncology, Taussig Cancer Institute, Cleveland Clinic, 2016
- Top Doctors in Cleveland 2014, 2015, 2016, 2017, 2018 - Cleveland Magazine
- Top Cancer Doctors in U.S, Newsweek, 2015
- U.S. News Top Doctor, Castle Connolly Medical Ltd, 2010 to 2018
- Selected to the Gold Human Honor Society (GHHS), 2011
- “Pink Tie Guy” – Selected by Susan G. Komen for the Cure, WV 2010
- Dean’s Award for Excellence in Clinical Medicine, School of Medicine, West Virginia University, 2010
- Quality Award (Customer Satisfaction), West Virginia University Hospitals, 2006-2013
- President of India, Her Excellency, Smt. Pratibha Patil “Vaidya Bhooshan”, by the Pazhassi Raja Trust, New Delhi, India, 2010
- Bonnie Wells Wilson Eminent Scholar and Distinguished Professor in Breast Cancer Research, 2009
- Outstanding Achievement in Medicine, Kerala Center, India League, New York, 2008
- Outstanding Faculty Award, Department of Medicine, West Virginia University, 2007
- STAR Award for customer service, West Virginia University Hospital, 2006
- Clinician of the Year Award, Department of Medicine, West Virginia University, 2006
- Volunteer of the Year Award for the state of West Virginia, American Cancer Society (ACS) 2006
Innovations & Patents
- Population Based Molecular Prognosis of Breast Cancer by Transcriptional Profiling by 28 Gene Assay, 2007 (Provisional Serial Number: 60/919,369
- Nonlinear Characterization of Breast Cancer using Multi-Compression 3D Ultrasound Elastography (Patent pending) Nonlinear Characterization of Breast Cancer using Multi-Compression 3D Ultrasound Elastography (Patent pending)
Memberships
- American Society of Clinical Oncology (ASCO)
- American College of Physicians (ACP)
- American Association of Cancer Research (AACR)
Research & Publications
See publications for Jame Abraham, MD.
(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)
Industry Relationships
Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.
To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.
As of 4/28/2025, Dr. Abraham has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.
Consulting and/or Speaking. Dr. Abraham receives fees of $5,000 or more per year (or, in rare cases, equity or stock options) as a paid consultant, speaker or as a member of an advisory committee for the following companies:
- Clinical Care Options, LLC
Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.
* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.
127 Patient Satisfaction Reviews
The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.
Responses are measured on a scale of 1 to 5 with 5 being the best score.
The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.
| Overall | Star Ratings | |
|---|---|---|
| Explains | 5 | |
| Courtesy, Respect & Concern | 5 | |
| Patient Rating of Doctor | 5 |
35 Patient Comments
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Reviewed on Apr 2, 2025
Dr. Abraham has been such a blessing during this experience with cancer and survivorship
Reviewed on Mar 6, 2025
Dr. Abraham is phenomenal. Not only does he have a wealth of knowledge about my diagnosis, he is also a very friendly and caring person. He didn't hesitate to express his delight in seeing me after several years since our first visit. He is wonderful!
Reviewed on Mar 5, 2025
I love Dr. Abraham! His calm and un-rushed demeanor, warm smile and personality make me feel as though he truly cares about my particular case... I'm not just a number to him.
Reviewed on Feb 19, 2025
Dr Abraham is amazing He is genuine, honest and comforting
Reviewed on Feb 6, 2025
Dr Abraham was wonderful. He is knowledgeable, experienced and caring. I respect his judgement.
Reviewed on Feb 6, 2025
Doctors took their time to explain in such a proper manner that I could grasp and feel cured. It was so nice definitely more than a five star service thank you team for such a care.
Reviewed on Feb 5, 2025
Dr J Abraham is hands down one of the best providers I've ever meet, been his patient for over 10yrs now. Highly recommend if faced with cancer.
Reviewed on Jan 22, 2025
Dr Abraham really listens and pays close attention to my questions and concerns. He offers excellent advice and considers my perspective.
Reviewed on Jan 8, 2025
Both Dr. Abraham and his nurse, Nancy provide outstanding care.
Reviewed on Jan 8, 2025
Dr Abraham is without question the finest physician i've had in my 73 years. He is exemplary!
Reviewed on Jan 8, 2025
Dr. Abraham is a kind and compassionate physician. He takes his time and makes sure that the patient is comfortable with the care plan and has all questions answered.
Reviewed on Jan 2, 2025
Dr Abraham and his team are amazing!
Reviewed on Dec 18, 2024
Dr. Abraham and his staff are the best. Very accessible for questions and or scheduling an appointment.
Reviewed on Dec 4, 2024
Dr. Abraham and Nancy are the best!
Reviewed on Dec 4, 2024
Dr Abraham is a very compassionate doctor who is willing to work with other doctors to help ensure you get the best care.
Reviewed on Dec 4, 2024
Dr. Abraham is a compassionate doctor who does not rush through exams. He is very personable and kind. He does everything he can to make patient feel comfortable and understand treatment/ care plan.
Reviewed on Dec 4, 2024
I have recommended Dr. Abraham to several other people, and will continue to do so. He and his staff are a true asset to the Clinic!
Reviewed on Dec 4, 2024
Exceptional care. I feel very lucky to be a patient of Dr. Abraham and Nancy.
Reviewed on Nov 27, 2024
I am always so impressed by Dr. Abraham and his wonderful team! As busy as I'm sure Dr. Abraham is, you would never know. He takes his time to really listen, follows up on what we discussed a year ago and is so kind and knowledgeable! I always enjoy my visits with him, despite the reason I am there.
Reviewed on Nov 21, 2024
So far I'm very pleased with Dr. Abraham and his team.
Reviewed on Nov 13, 2024
Nancy and Dr. Abraham were unbelievably knowledgable, friendly and courteous. I cannot begin to express how wonderful my experience was with them and their team.
Reviewed on Sep 18, 2024
Thank you Dr. Abrahame for showing such empathy and concern for myself, husband, sister and our son. After we suffered a motor vehicle accident over Labor Day weekend with multiple Injuries. Dr. Abrahame sat down and just patiently asked questions and offered support to our family. Thank you for your extreme kindness during this difficult time.
Reviewed on Sep 12, 2024
I feel Dr Abraham and his team are both professional and compassionate. Dr Abraham is doing exactly what he promised, walking through this journey together with me to ensure the best outcome.
Reviewed on Sep 12, 2024
Dr Abraham took so much time with me! He was so kind and very thorough in his explanations, and we never felt rushed at all, even though it was after 5 o'clock he just let me go on with my questions.
Reviewed on Sep 11, 2024
Always a great experience with Dr. Abraham. Dr. Abraham is not only highly knowledgeable, but also, compassionate.
Reviewed on Sep 11, 2024
Because of how good Dr. Abraham is at what he does, I have been sending anyone who I personally know who is going though same as me, to come see Dr. Abraham at Cleveland clinic. I personally drive almost 4 hours each way just to reserve health care provided by Dr. Abraham and Dr. Abrahams team members
Reviewed on Sep 5, 2024
Dr Abraham and his entire team were wonderful and took their time explaining everything to me and everyone was very empathetic towards me and my health situation
Reviewed on Aug 8, 2024
Dr. Abraham is extremely professional & knowledgeable about my needs.
Reviewed on Jul 31, 2024
Dr. Abraham is amazing. The quality of care that I received from him is several steps above what I would be able to receive locally.
Reviewed on Jul 25, 2024
My team of doctors are all very caring and listen to all my questions and answers them throughly
Reviewed on Jul 24, 2024
Dr Abraham took the time to understand my symptoms and is looking to provide solution! I appreciate his care
Reviewed on Jun 27, 2024
Dr. Abraham is excellent. He is a proactive Doctor that will make sure everything is checked out. He is concerned with my mental health as well as physical health.
Reviewed on May 29, 2024
I am extremely fortunate to have Dr.Abraham as my oncologist.
Reviewed on May 15, 2024
Dr. Abraham and Nancy were both very professional but took the time to get to know me, and to discuss/explain my plan of treatment.
Reviewed on May 9, 2024
My visit with Dr. Abraham was all good!