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Department Hematology and Medical Oncology
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English
Surgeon No
Locations Specialties & Treatments

Treatment & Services

  • 2nd Opinion Evaluations
  • Blood Tests
  • Blood Transfusion
  • Cancer
  • Cancer Center
  • Cancer Supportive Care
  • Chemoprevention
  • Chemotherapy
  • Clinical Drug Trials
  • Clinical Trials
  • Endocrine Aspects of Cancer
  • Endocrine Treatment
  • High Risk Breast Cancer
  • Immunotherapy
  • Targeted Treatment
  • Women's Health
View all 16 Treatment & Services +

Specialty in Diseases & Conditions

  • Breast - Malignant Neoplasm
  • Breast Cancer
  • Breast Cancer - Mass, Lump or Swelling
  • Cancer Symptoms
  • Male Breast Cancer
  • Metastatic Breast Cancer
  • Metastatic Cancer
View all 7 Specialties +


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About Jame Abraham, MD

Jame Abraham, MD, FACP, is Chairman of the Department of Hematology & Medical Oncology at Cleveland Clinic and Professor of Medicine at Cleveland Clinic Lerner College of Medicine.

From 2013 to 2019, Dr. Abraham served as director of the Cleveland Clinic Breast Oncology Program, and co-Director of the Cleveland Clinic Comprehensive Breast Cancer Program, until he was promoted to Department Chairman.  He has more than 17 years of experience of treating complicated breast cancer diagnoses, from early stage to metastatic, and leading novel clinical trials. 

Dr. Abraham is a member of the National Comprehensive Cancer Network (NCCN) Breast Cancer Committee, which sets treatment guidelines for breast cancer management across the United States. He is Vice Chair of the Research Strategy Committee of NRG Oncology, one of the largest cancer research groups in the world, funded by the National Cancer Institute. Dr. Abraham is also a member of the Breast Committee Working Group for NRG Oncology. He is the Vice Chair of the Research Review Committee for the National Surgical Adjuvant Breast and Bowel Project (NSABP) and a member of the Scientific Advisory Board for NSABP.

Dr. Abraham completed his residency at the University of Connecticut School of Medicine, followed by a Medical Oncology Fellowship from the National Cancer Institute (NCI) and Hematology Fellowship from the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health (NIH). Dr. Abraham earned his medical degree from Calicut Medical College, Kerala, India.

At the NCI, Dr. Abraham was the study chair of several early-phase clinical trials that included novel treatments for breast cancer such as Ixabepilone, which was approved by the FDA in 2007. During his fellowship, Dr. Abraham edited the first edition of the Bethesda Handbook of Oncology (Lippincott Williams and Wilkins). Now in its 5th edition, it is one of the best-selling oncology textbooks in the world. It is considered the standard textbook by many universities and hospitals across the world. 

After finishing fellowship, Dr. Abraham joined West Virginia University (WVU) in 2001 as an Assistant Professor. In 2005, he was appointed Chief of Hematology/Oncology and was later appointed as the first Bonnie Wells Wilson Distinguished Professor of Breast Cancer Research, and Professor of Medicine of WVU. While at WVU, Dr. Abraham established the first comprehensive breast cancer program in the state of West Virginia in 2002. He received several awards from WVU for patient care and teaching, including Attending of the Year and Teacher of the Year. His outstanding work in patient care was recognized by the Excellence in Clinical Medicine award from the Dean of the School of Medicine in 2010. He received an award from the President of India, Her Excellency Mrs. Pratibha Patil for his contribution to cancer care in 2010.

Dr. Abraham leads several national and local clinical trials to find better treatment options for early stage, metastatic, triple negative and her-2 positive breast cancer patients. He has more than 200 papers and presentations at national meetings. 

In 2017, he received the Teacher of the Year award from the Cleveland Clinic Taussig Cancer Institute medical oncology fellows and was nominated for the Distinguished Staff Teacher of the Year Award by the Cleveland Clinic Internal Medicine Residents.  He has been selected by Cleveland Magazine and Newsweek as a top oncologist locally and nationally, respectively. 

Dr. Abraham’s primary focus and passion is taking care of patients with breast cancer. 

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - National Cancer Institute
Medical Oncology
Bethesda, MD USA

Fellowship - National Heart, Lung and Blood Institute
Bethesda, MD USA

Residency - University of Connecticut
Internal Medicine
Farmington, CT USA

Medical Education - Calicut Medical College
Calicut, Kerala, India,

Undergraduate - Calicut Medical College
Calicut, Kerala, India,

Additional Training

  • Senior Fellow, Developmental Therapeutics, National Cancer Institute 2001
  • Leadership Development for Physicians in Academic Health Centers, School of Public Health, Harvard, Boston. 2006

Professional Highlights

  • Chairman, Cleveland Clinic Department of Hematology & Medical Oncology
  • Professor of Medicine, Cleveland Clinic Lerner College of Medicine
  • Medical Director, Community Outreach, Taussig Cancer Institute
  • Member, NCCN, Breast Cancer Committee
  • Vice Chair, Research Strategy, NRG Oncology
  • Co-Director, Cleveland Clinic Comprehensive Breast Cancer Program (2013-2019)
  • Member, Breast Cancer Working Committee, NRG Oncology (2019- 2022)
  • Member, Breast Cancer Committee, NRG Oncology (2015-Present)   
  • Member, Translational Research Committee, NRG Oncology (2015-18)
  • Co-Principal Investigator, Leading Academic Participating Sites (LAPS), National Cancer Institute  grant for the Case Comprehensive Cancer Center (2014-2017)
  • Principal Investigator of NSABP for Cleveland Clinic (2013 to present)
  • Vice Chair, Research Review Committee, NSABP Foundation (2013-Present)
  • Member of Breast Cancer Working Group, NSABP (2010-2013)
  • Founding Editor of Bethesda Handbook of Clinical Oncology, Wolter Kluwer, Philadelphia (5th edition)
  • Chief Editor, Emerging Cancer Therapeutics, Demos, New York
  • Editor, Community and Supportive Care Oncology (Frontline Communications, NJ)
  • Editor, Breast Cancer Management and Treatment (London, U.K)
  • Associate Editor and Guest Editor, ASCO Post (Harborside Press, NY)
  • Board of Directors, American Cancer Society, South Atlantic Division (2007-2010)
      • Editorial Board Member:
        • Journal of Breast Cancer Management, Future Science Group, London, U.K, Oncology and Biotechnology News, New Jersey, Expert Review of Anticancer Therapy, Future Science Group, London, U.K.
      • Manuscript Reviewer:
        • Lancet Oncology, Lancet
        • Journal of Clinical Oncology, ASCO
        • Clinical Cancer Research Focus, AACR
        • Human Bain Mapping
        • Expert Review of Immunotherapy
        • Clinical Breast Disease
        • British Journal of Cancer, Nature Publications Group
        • Annals of Saudi Medicine
        • Clinical Cancer Research, AACR
        • Expert Review of Anticancer Therapy
        • Cancer: American Cancer Society
        • Cancer Chemotherapy and Pharmacology


  • Internal Medicine - Medical Oncology

Specialty Interests

Breast Cancer treatment, Clinical Trials

Awards & Honors

  • Teacher of the Year Award: Oncology, Taussig Cancer Institute, Cleveland Clinic, 2016
  • Top Doctors in Cleveland 2014, 2015, 2016, 2017, 2018 -  Cleveland Magazine
  • Top Cancer Doctors in U.S, Newsweek, 2015
  • U.S. News Top Doctor, Castle Connolly Medical Ltd, 2010 to 2018  
  • Selected to the Gold Human Honor Society (GHHS), 2011
  • “Pink Tie Guy” – Selected by Susan G. Komen for the Cure, WV 2010
  • Dean’s Award for Excellence in Clinical Medicine, School of Medicine, West Virginia University, 2010
  • Quality Award (Customer Satisfaction), West Virginia University Hospitals, 2006-2013
  • President of India, Her Excellency, Smt. Pratibha Patil “Vaidya Bhooshan”, by the Pazhassi Raja Trust, New Delhi, India, 2010
  • Bonnie Wells Wilson Eminent Scholar and Distinguished Professor in Breast Cancer Research, 2009
  • Outstanding Achievement in Medicine, Kerala Center, India League, New York, 2008
  • Outstanding Faculty Award, Department of Medicine, West Virginia University, 2007
  • STAR Award for customer service, West Virginia University Hospital, 2006
  • Clinician of the Year Award, Department of Medicine, West Virginia University, 2006
  • Volunteer of the Year Award for the state of West Virginia, American Cancer Society (ACS) 2006

Innovations & Patents

    1. Population Based Molecular Prognosis of Breast Cancer by Transcriptional Profiling by 28 Gene Assay, 2007 (Provisional Serial Number: 60/919,369
    2. Nonlinear Characterization of Breast Cancer using Multi-Compression 3D Ultrasound Elastography (Patent pending) Nonlinear Characterization of Breast Cancer using Multi-Compression 3D Ultrasound Elastography (Patent pending)


  • American Society of Clinical Oncology (ASCO)
  • American College of Physicians (ACP)
  • American Association of Cancer Research (AACR)
Research & Publications

Research & Publications

See publications for Jame Abraham, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 1/2/2021, Dr. Abraham has reported no financial relationship with industry that is applicable to this listing. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

124 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
5 out of 5
Explains 4.9
Listens 3.7
Courtesy, Respect & Concern 5
Patient Rating of Doctor 5

41 Patient Comments

Reviewed on Nov 4, 2021

I have the highest regard for Dr Abraham. I always leave more informed and lightheaded. He is kind, thoughtful and a wonderful human being

Reviewed on Nov 3, 2021

Dr. Jame Abraham is truly the best of the best in every category.

Reviewed on Sep 29, 2021

Dr Abraham is the best!

Reviewed on Sep 22, 2021

Dr. Abraham had a fellow with him that day. The fellow was professional and respectful. There is no one like Dr. Abraham! Dr. Abraham exudes confidence and compassion such that I always feel that I have come to the right place. He is kind, compassionate and he reads me well. He always answers my questions honestly and In a straight-forward manner and with data and experience to back up his recommendations. I relax knowing I am in the hands of an expert. I come from out of town to see him by choice. I know I have had the best care and I commend him, his staff and CCF for helping cancer patients to feel they have power over these terrible diseases.

Reviewed on Sep 2, 2021

I was amazed at how well Dr. Abraham and Dr. Barot, knew my case.

Reviewed on Sep 2, 2021

I am so impressed at with how the providers worked together and communicated with one another. Wonderful experience so far.

Reviewed on Sep 1, 2021

I had a wonderful experience and am so grateful to Dr. Abraham and his team!!

Reviewed on Sep 1, 2021

Dr. Abraham is an amazing provider and I had a great appointment. He is careful to provide helpful explanations and answer all questions!

Reviewed on Aug 11, 2021

I value dr Abraham as been a great doctor. He listened and helps us to understand.

Reviewed on Aug 5, 2021

Dr. Abraham explained to me the very complex situation in such detail, in a clear and understandable method. I had never received such information that I completely understood at all levels. I traveled from FL to have this visit. I care I received was second to none.

Reviewed on Aug 4, 2021

Dr. Abraham is an amazing doctor and person. His compassion and care for me as a patient and person means the world to me! His knowledge and expertise eases my worries.

Reviewed on Jul 29, 2021

Doctor Abraham is the best physician that I have ever met.

Reviewed on Jul 29, 2021

Dr.Jame Abraham is a gift from God. CC should make sure they take good care of him because you will never find another doctor like him. He is one in a million!

Reviewed on Jul 28, 2021

Dr. Jaime Abraham is always kind and helpful and is an excellent oncologist.

Reviewed on Jul 28, 2021

How I thank God for Dr. Abraham! He cared about my whole health. Besides my cancer, he was also very careful about my heart. He is most encouraging, caring, knowledgeable, listening, and gentle. I can't say enough good about him! I always want him for my doctor. To me, he is the greatest!

Reviewed on Jul 22, 2021

I was very satisfied with the care I received from Dr. Abraham

Reviewed on Jul 21, 2021

I love Dr. Abraham and his team. He is always so kind and takes his time with me.

Reviewed on Jul 7, 2021

Dr. Abraham is wonderful. Professional, informative, kind. I always feel better after meeting with him.

Reviewed on Jun 16, 2021

Always a pleasure to speak w/Dr Abraham. He's very kind and personable and doesn't rush you!!

Reviewed on Jun 16, 2021

Best Doctor ever!!! So glad I was referred to him!!

Reviewed on Jun 9, 2021

Dr Jame Abraham is the best oncologist there is. I praise & recommend him to everyone.

Reviewed on May 19, 2021

My physicians care was superb. I have recommended him to others.

Reviewed on Apr 21, 2021

The visit was awesome Dr Jame Abraham make my appointment go so smoothly. He is really genuine in the care of his patient. His nurse Nancy also is a very great nurse she is so dependable when she is needed for anything.

Reviewed on Mar 25, 2021

Dr. Abraham is just wonderful! He takes the time to listen and he always follows up and asks questions regarding personal topics we covered during the last visit. In addition to his exceptional bedside manner, I completely trust him with my health and treatment plan!!

Reviewed on Mar 25, 2021

I always recommend Dr. Abraham's office to friends and family going thru Breast Cancer.

Reviewed on Mar 25, 2021

Dr Abraham is an awesome doc and person. Very caring and kind. Always makes me feel cared about

Reviewed on Jan 28, 2021

Dr. Abaham is a very caring, personable doctor. I have recommended him to others, and they also have the same opinion.

Reviewed on Jan 13, 2021

Dr. Abraham is always very kind and concerned about you.

Reviewed on Jan 7, 2021

Dr. Abraham is great! I had high expectations and he lived up to them.

Reviewed on Jan 6, 2021

Dr Abraham is a gift from God.

Reviewed on Jan 6, 2021

Can not say enough GOOD about Dr Jame Abraham! He is a caring, thoughtful and passionate Doctor. He has always made me feel like a person/friend rather than a patient with cancer. He takes time to explain and answers all of my questions even if I had already asked him. Very personable, if it wasn't for him I would NOT be at Cleveland Clinic for you know we have choices! His assistant Nancy is very helpful!

Reviewed on Dec 23, 2020

Dr Abraham was compassionate and walked me through test results, diagnosis and potential treatment plan in a way that gave me comfort

Reviewed on Dec 10, 2020

Dr. Abraham accomodated my tight schedule.

Reviewed on Dec 9, 2020

Although I had to wait for an in-person appointment with Dr. Abraham, I am grateful that the scheduler and Nancy Dalpiazi arranged one for me during this terrible time of the pandemic when doctors have to be so careful about being exposed to the virus.

Reviewed on Dec 2, 2020

All on "Team Dr. Abraham" are kind, approachable, positive and reassuring. Even the woman at the check-in desk raved about Dr. Abraham - the competent and very kind man/doctor he is and how my husband and I will be taken care of by him and his staff.

Reviewed on Dec 2, 2020

I have been a Clinic patient since 1994 when Dr. Jerome Belinson found my first cancer. He was great, as was the Clinic, and Dr. Abraham is phenomenal this time around. My husband and I, while receiving a tough and scary diagnosis, were wrapped in his care and concern. Dr. Abraham, with great skill, threaded the needle between delivering harsh facts in an emotionally charged situation and a soothing professionalism and respect for us. He explained medically and physiologically the changes in my body with directness overlayed with a plan to help me. Deliberate in his word choices; skilled in his practice; reassuring in his experience; and caring in his approach, Dr. Abraham made a very difficult day manageable for my husband and me. His follow up is as impressive as it is welcomed and we have never experienced this level of care and I've had some great doctors at the Clinic over the decades. I have tried to find the words to describe him and our experience, but even the words here can't quite describe Dr. Abraham and our recent experiences with him.

Reviewed on Dec 2, 2020

The staff is a cohesive unit that cares deeply. I would HIGHLY recommend Dr. Abraham and his entire Team. My process has been swift, efficient and VERY easy in moving through this large system.

Reviewed on Nov 12, 2020

Dr. Abraham could not be more caring and attentive. I am so fortunate do have him as my oncologist.

Reviewed on Nov 12, 2020

I had a wonderful experience with Dr. Abraham!

Reviewed on Nov 12, 2020

I really appreciated Dr. Abrahams insights and recommendations, and he explained everything extremely well!

Reviewed on Nov 12, 2020

Dr. James Abraham was not only caring but explained everything to me in detail. My visit with him was the best visit I have had since the start of this journey 6 years ago. He confirmed all of the thoughts and plans I thought were appropriate for my care. He is a wonderful Dr. with a superb bedside manner. I wish he was a bit closer to me but I will remain in contact with him through zoom appointments and in person follow ups whenever he feels necessary. I hope telehealth visits remain an option long after the Pandemic is over.

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