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Department Hematology and Medical Oncology
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English, Hindi, Malayalam
Surgeon No
Locations Specialties & Treatments

Treatment & Services

  • 2nd Opinion Evaluations
  • Blood Tests
  • Blood Transfusion
  • Cancer
  • Cancer Center
  • Cancer Supportive Care
  • Chemoprevention
  • Chemotherapy
  • Clinical Drug Trials
  • Clinical Trials
  • Endocrine Aspects of Cancer
  • Endocrine Treatment
  • High Risk Breast Cancer
  • Immunotherapy
  • Targeted Treatment
  • Women's Health
View all 16 Treatment & Services +

Specialty in Diseases & Conditions

  • Breast - Malignant Neoplasm
  • Breast Cancer
  • Breast Cancer - Mass, Lump or Swelling
  • Cancer Symptoms
  • Male Breast Cancer
  • Metastatic Breast Cancer
  • Metastatic Cancer
View all 7 Specialties +


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About Jame Abraham, MD

Jame Abraham, M.D., FACP, is the chairman of the Department of Hematology & Medical Oncology at Cleveland Clinic and professor of medicine at Cleveland Clinic Lerner College of Medicine. From May 2021 to July 2022, he served as interim chair of the Taussig Cancer Institute and deputy director of the Case Comprehensive Cancer Center.

Dr. Abraham was director of the Cleveland Clinic Breast Oncology Program, and co-director of the Cleveland Clinic Comprehensive Breast Cancer Program from 2013 to 2019. He has more than 20 years of experience treating complicated breast cancer diagnoses, from early stage to metastatic, and leading novel clinical trials. 

Dr. Abraham is a member of the National Comprehensive Cancer Network (NCCN) Breast Cancer Committee, which sets treatment guidelines for breast cancer management across the United States. He is the vice chair of the Research Strategy Committee of NRG Oncology, one of the largest cancer research groups in the world, funded by the National Cancer Institute (NCI). Dr. Abraham also is a member of the Breast Committee Working Group of NRG Oncology. He is the vice chair of the Research Review Committee for the National Surgical Adjuvant Breast and Bowel Project (NSABP) and a member of the Scientific Advisory Board for NSABP.

Dr. Abraham completed his residency at the University of Connecticut School of Medicine, followed by a medical oncology fellowship from the National Cancer Institute (NCI) and hematology fellowship from the National Heart, Lung, and Blood Institute of the National Institutes of Health. Dr. Abraham earned his medical degree from Calicut Medical College, Kerala, India.

At the NCI, Dr. Abraham was the study chair of several early-phase clinical trials that included novel treatments for breast cancer, such as Ixabepilone, which was approved by the FDA in 2007. During his fellowship, Dr. Abraham edited the first edition of the Bethesda Handbook of Oncology (Lippincott Williams and Wilkins). Now in its sixth edition, it is one of the best-selling oncology textbooks in the world and considered the standard textbook by many universities and hospitals. 

Dr. Abraham is deputy editor of Journal of Oncology Practice of American Society of Clinical Oncology (ASCO) and associate editor of ASCO Post.

After finishing fellowship training, Dr. Abraham joined West Virginia University (WVU) in 2001 as an assistant professor. In 2005, he was appointed chief of hematology/oncology. He also served as the first Bonnie Wells Wilson Distinguished Professor of Breast Cancer Research and a professor of medicine of WVU. Dr. Abraham established the first comprehensive breast cancer program in West Virginia in 2002. He received several awards from WVU for patient care and teaching, including “Attending of the Year” and “Teacher of the Year.” His outstanding work in patient care was recognized by the Excellence in Clinical Medicine award from the dean of the school of medicine in 2010. That year he received an award from the President of India, Her Excellency Mrs. Pratibha Patil for his contribution to cancer care.

Dr. Abraham has been involved with several national clinical trials, many of which are NSABP trials, to find better treatment options for early-stage, metastatic, triple-negative and HER-2 positive breast cancer patients. He is the North American study chairman of DESTINY 05 (NSABP B 60 trial), which is a global adjuvant breast cancer clinical trial with Trastuzumab Deruxetecan , which will enroll nearly 2,000 patients from more than 30 countries.

He has contributed more than 200 papers and presentations at national and international meetings, and has had his work published in journals such as Journal of Clinical Oncology, JAMA, JAMA Oncology and Clinical Cancer Research.

Dr. Abraham’s primary focus and passion is taking care of patients with breast cancer. 

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - National Cancer Institute
Medical Oncology
Bethesda, MD USA

Fellowship - National Heart, Lung and Blood Institute
Bethesda, MD USA

Residency - University of Connecticut
Internal Medicine
Farmington, CT USA

Medical Education - Calicut Medical College
Calicut, Kerala, India,

Undergraduate - Calicut Medical College
Calicut, Kerala, India,

Additional Training

  • Senior Fellow, Developmental Therapeutics, National Cancer Institute 2001
  • Leadership Development for Physicians in Academic Health Centers, School of Public Health, Harvard, Boston. 2006

Professional Highlights

  • Chairman, Cleveland Clinic Department of Hematology & Medical Oncology
  • Professor of Medicine, Cleveland Clinic Lerner College of Medicine
  • Medical Director, Community Outreach, Taussig Cancer Institute
  • Member, NCCN, Breast Cancer Committee
  • Vice Chair, Research Strategy, NRG Oncology
  • Co-Director, Cleveland Clinic Comprehensive Breast Cancer Program (2013-2019)
  • Member, Breast Cancer Working Committee, NRG Oncology (2019- 2022)
  • Member, Breast Cancer Committee, NRG Oncology (2015-Present)   
  • Member, Translational Research Committee, NRG Oncology (2015-18)
  • Co-Principal Investigator, Leading Academic Participating Sites (LAPS), National Cancer Institute  grant for the Case Comprehensive Cancer Center (2014-2017)
  • Principal Investigator of NSABP for Cleveland Clinic (2013 to present)
  • Vice Chair, Research Review Committee, NSABP Foundation (2013-Present)
  • Member of Breast Cancer Working Group, NSABP (2010-2013)
  • Founding Editor of Bethesda Handbook of Clinical Oncology, Wolter Kluwer, Philadelphia (5th edition)
  • Chief Editor, Emerging Cancer Therapeutics, Demos, New York
  • Editor, Community and Supportive Care Oncology (Frontline Communications, NJ)
  • Editor, Breast Cancer Management and Treatment (London, U.K)
  • Associate Editor and Guest Editor, ASCO Post (Harborside Press, NY)
  • Board of Directors, American Cancer Society, South Atlantic Division (2007-2010)
      • Editorial Board Member:
        • Journal of Breast Cancer Management, Future Science Group, London, U.K, Oncology and Biotechnology News, New Jersey, Expert Review of Anticancer Therapy, Future Science Group, London, U.K.
      • Manuscript Reviewer:
        • Lancet Oncology, Lancet
        • Journal of Clinical Oncology, ASCO
        • Clinical Cancer Research Focus, AACR
        • Human Bain Mapping
        • Expert Review of Immunotherapy
        • Clinical Breast Disease
        • British Journal of Cancer, Nature Publications Group
        • Annals of Saudi Medicine
        • Clinical Cancer Research, AACR
        • Expert Review of Anticancer Therapy
        • Cancer: American Cancer Society
        • Cancer Chemotherapy and Pharmacology


  • Internal Medicine - Medical Oncology

Specialty Interests

Breast Cancer treatment, Clinical Trials

Awards & Honors

  • Teacher of the Year Award: Oncology, Taussig Cancer Institute, Cleveland Clinic, 2016
  • Top Doctors in Cleveland 2014, 2015, 2016, 2017, 2018 -  Cleveland Magazine
  • Top Cancer Doctors in U.S, Newsweek, 2015
  • U.S. News Top Doctor, Castle Connolly Medical Ltd, 2010 to 2018  
  • Selected to the Gold Human Honor Society (GHHS), 2011
  • “Pink Tie Guy” – Selected by Susan G. Komen for the Cure, WV 2010
  • Dean’s Award for Excellence in Clinical Medicine, School of Medicine, West Virginia University, 2010
  • Quality Award (Customer Satisfaction), West Virginia University Hospitals, 2006-2013
  • President of India, Her Excellency, Smt. Pratibha Patil “Vaidya Bhooshan”, by the Pazhassi Raja Trust, New Delhi, India, 2010
  • Bonnie Wells Wilson Eminent Scholar and Distinguished Professor in Breast Cancer Research, 2009
  • Outstanding Achievement in Medicine, Kerala Center, India League, New York, 2008
  • Outstanding Faculty Award, Department of Medicine, West Virginia University, 2007
  • STAR Award for customer service, West Virginia University Hospital, 2006
  • Clinician of the Year Award, Department of Medicine, West Virginia University, 2006
  • Volunteer of the Year Award for the state of West Virginia, American Cancer Society (ACS) 2006

Innovations & Patents

    1. Population Based Molecular Prognosis of Breast Cancer by Transcriptional Profiling by 28 Gene Assay, 2007 (Provisional Serial Number: 60/919,369
    2. Nonlinear Characterization of Breast Cancer using Multi-Compression 3D Ultrasound Elastography (Patent pending) Nonlinear Characterization of Breast Cancer using Multi-Compression 3D Ultrasound Elastography (Patent pending)


  • American Society of Clinical Oncology (ASCO)
  • American College of Physicians (ACP)
  • American Association of Cancer Research (AACR)
Research & Publications

Research & Publications

See publications for Jame Abraham, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 2/2/2023, Dr. Abraham has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Consulting and/or Speaking. Dr. Abraham receives fees of $5,000 or more per year as a paid consultant, speaker or member of an advisory committee for the following companies:

  • Aptitude Health, LLC
  • Curio Science LLC

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

35 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
5 out of 5
Explains 5
Courtesy, Respect & Concern 5
Patient Rating of Doctor 5

31 Patient Comments

Reviewed on Mar 8, 2023

Excellent service! Love Dr Abram, he's awesome, highly recommended.

Reviewed on Mar 8, 2023

Highly recommend Dr Abram.

Reviewed on Feb 23, 2023

Dr. Abraham was one of the two nicest, compassionate, patient centered oncologists I see. Top notch! No wonder people travel to the Cleveland Clinic from all over the world for their care.

Reviewed on Feb 22, 2023

Absolutely LOVE Dr. Abraham. He is very kind and personable. He listens and really cares about his patients.

Reviewed on Feb 22, 2023

While I really appreciate video visits (esp since I live 3 hours from Cleveland) in person feels more personable. However I wouldn't change this because it allowed me to continue working and not having to rearrange my entire day to see the doctor. I really appreciate that this is an option!

Reviewed on Feb 15, 2023

The best! Never rushes, friendly, thoughtful in his responses. I am alive because of Dr. Abraham. And Brenna, his trial nurse is AMAZING! She has helped me through so much, above and beyond her trial responsibilities!

Reviewed on Feb 9, 2023

Dr Abraham is the best doctor

Reviewed on Jan 26, 2023

There are only a few providers I will recommend to anyone... Dr. Abraham is one of them. Sat down beside me, drew a chart on what I have and what treatments I can and cannot do and explained in full detail every step. He was very kind, caring, and personable. He is a treasure!

Reviewed on Jan 18, 2023

Dr Abraham is amazingTook his time and explained everything very thorough

Reviewed on Jan 12, 2023

Dr. Abraham made it extremely easy for me to make an appointment and see him at a time that worked out

Reviewed on Jan 12, 2023

Dr. Abraham was amazing. Not only is he a very top cancer doctor, but he is such a nice person. I feel very confident to be in his care and feel a lot better about my situation since I've seen him.

Reviewed on Dec 21, 2022

Dr. Abraham and his staff are the best providers. He takes time with me and I never feel rushed. He knows where my anxiety lies and tries to help relieve that anxiety by calling me at home with test results. He is truly the kindest human being.

Reviewed on Dec 21, 2022

Dr Abraham is an outstanding physician

Reviewed on Dec 21, 2022

Dr. Abraham is an excellent doctor. He is knowledgeable, professional, compassionate and kind.

Reviewed on Dec 21, 2022

Dr Abraham is so kind and respectful.

Reviewed on Dec 21, 2022

Dr. Abraham is incredible. He is extremely competent, compassionate, and considerate of a patient's needs.

Reviewed on Oct 12, 2022

Dr. Abraham is the best and while I am happy to be released, I will miss being in his care. He is very knowledgeable, caring and supportive.

Reviewed on Sep 2, 2022

Thank you Dr. Abrahame for seeing us so quick to determine a plan for care for a recurrence of breast cancer

Reviewed on Sep 2, 2022

Dr. Abrahame took the time to talk not only with me but my spouse and sister. He sat down and wrote out a plan and took the time to include our needs in the plan. Treating me as an individual and not just as a patient

Reviewed on Jul 27, 2022

Dr. Abraham listened to my concerns, addressed my questions and I really value his opinion.

Reviewed on Jun 29, 2022

Dr. Abraham is the best as is his nurse, Nancy.

Reviewed on Jun 23, 2022

Dr Abraham is outstanding in every way and it is greatly appreciated I the joint decision-making process about my care

Reviewed on Jun 22, 2022

Dr Abraham is compassionate, knowledgeable, diligent and really cares about his patients. It is always a happy day after visiting him.

Reviewed on Jun 15, 2022

My doctor is always very kind and courteous and so helpful in explaining things. I have always enjoyed Dr. Abram. He makes me feel at ease and confident and always listens to me.

Reviewed on Jun 15, 2022

Dr. Abraham is the best. Always kind and patient. He never rushes us out of the office.

Reviewed on Jun 8, 2022

I feel very fortunate to have had Dr. Jame Abraham as my oncologist. He was kind but straightforward and prepared me for what was to come. As things changed due to my condition he kept in touch, always listening in a kind and compassionate manner.

Reviewed on Jun 1, 2022

I am very lucky to have Dr. Abraham as my Oncologist. Every visit he gave me enough time to explain all my questions. His compassion, knowledge & patience make him the best oncologist. .

Reviewed on May 18, 2022

We love Dr. J. Abraham

Reviewed on Apr 13, 2022

Was just a routine check up. But Dr Abrahams resident was very thorough and knowledgeable about my case. Dr Abraham was also very thorough

Reviewed on Apr 13, 2022

Always a pleasure to see Dr. Abraham.

Reviewed on Mar 23, 2022

Dr. Abraham always is pleasant and listens to his patients. His warm and caring attitude is evident at every visit no matter where you are in your treatment plan. I see him yearly for a follow up and he displays his kindness and compassion still at this point.

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