Department Hematology and Medical Oncology
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English
Surgeon No
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus

Specialties & Treatments

Treatment & Services

  • 2nd Opinion Evaluations
  • Blood Tests
  • Blood Transfusion
  • Cancer
  • Cancer Center
  • Cancer Supportive Care
  • Chemoprevention
  • Chemotherapy
  • Clinical Drug Trials
  • Clinical Trials
  • Endocrine Aspects of Cancer
  • Endocrine Treatment
  • High Risk Breast Cancer
  • Immunotherapy
  • Targeted Treatment
  • Women's Health
View all 16 Treatment & Services +

Specialty in Diseases & Conditions

  • Brain Metastases
  • Breast - Malignant Neoplasm
  • Breast Cancer
  • Breast Cancer - Mass, Lump or Swelling
  • Cancer
  • Cancer Symptoms
  • Male Breast Cancer
  • Metastatic Breast Cancer
  • Metastatic Cancer
View all 9 Specialties +


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About Jame Abraham, MD

Jame Abraham, MD, FACP, is the Director of the Breast Oncology Program at Taussig Cancer Institute and Co-Director of the Cleveland Clinic Comprehensive Breast Cancer Program. Dr. Abraham is also a Professor of Medicine at Cleveland Clinic Lerner College of Medicine.

Dr. Abraham is a member of the National Comprehensive Cancer Network (NCCN) Breast Cancer Committee, which sets treatment guidelines for breast cancer management across the United States. He is Vice Chair of the Research Strategy Committee of NRG Oncology, one of the largest cancer research groups in the world, funded by the National Cancer Institute. Dr. Abraham is also a member of the Breast Committee Working Group for NRG Oncology. He is the Vice Chair of the Research Review Committee for the National Surgical Adjuvant Breast and Bowel Project (NSABP) and a member of the Scientific Advisory Board for NSABP.

Dr. Abraham completed his residency at the University of Connecticut School of Medicine, followed by a Medical Oncology Fellowship from the National Cancer Institute (NCI) and Hematology Fellowship from the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health (NIH). Dr. Abraham earned his medical degree from Calicut Medical College, Kerala, India.

At the NCI, he was the study chair of several early-phase clinical trials that included novel treatment for breast cancer such as Ixabepilone, which was approved by the FDA in 2007. During his fellowship, Dr. Abraham edited the first edition of the Bethesda Handbook of Oncology (Lippincott Williams and Wilkins). Now in its 5th edition, it is one of the best-selling oncology textbooks in the world. It is considered the standard textbook by many universities and hospitals across the world. 

After finishing fellowship, Dr. Abraham joined West Virginia University (WVU) in 2001 as an Assistant Professor. He was appointed Chief of Hematology/Oncology in 2005. He was later appointed as the first Bonnie Wells Wilson Distinguished Professor of Breast Cancer Research, and Professor of Medicine of West Virginia University (WVU). At WVU, Dr. Abraham established the first comprehensive breast cancer program in the state of West Virginia in 2002. He received several awards from WVU for patient care and teaching, including Attending of the Year and Teacher of the Year. His outstanding work in patient care was recognized by the Excellence in Clinical Medicine award from the Dean of the School of Medicine in 2010. He received an award from the President of India, Her Excellency Mrs. Pratibha Patil for his contribution to cancer care in 2010.

In 2013, Dr. Abraham joined Cleveland Clinic as director of the Breast Oncology Program, where he leads several national and local clinical trials to find better treatment options for early stage, metastatic, triple negative and her-2 positive breast cancer patients. 

He is the national Principal Investigator of the NSABP FB-10 (Neratinib and TDM-1) clinical trial for her-2 positive metastatic breast cancer. He has more than 200 papers and presentations at national meetings. 

In 2017, he received the Teacher of the Year award from the Medical Oncology fellows of Taussig Cancer Institute and was nominated as the Distinguished Staff Teacher of the Year Award by the Internal Medicine Residents of Cleveland Clinic.  He has been selected by Cleveland Magazine and Newsweek as a top oncologist locally and nationally, respectively. 

Dr. Abraham’s primary focus and passion is taking care of patients with breast cancer. 

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - National Cancer Institute
Medical Oncology
Bethesda, MD USA

Fellowship - National Heart, Lung and Blood Institute
Bethesda, MD USA

Residency - University of Connecticut
Internal Medicine
Farmington, CT USA

Medical School - Calicut Medical College
Calicut, Kerala, India,

Undergraduate - Calicut Medical College
Calicut, Kerala, India,

Additional Training

  • Senior Fellow, Developmental Therapeutics, National Cancer Institute 2001
  • Leadership Development for Physicians in Academic Health Centers, School of Public Health, Harvard, Boston. 2006

Professional Highlights

  • Professor of Medicine, Cleveland Clinic Lerner College of Medicine
  • Co-Principal Investigator, Leading Academic Participating Sites (LAPS), National Cancer Institute  grant for the Case Comprehensive Cancer Center (2014-2017)
  • Member, Breast Cancer Committee, NRG Oncology (2015-18)
  • Member, Translational Research Committee, NRG Oncology (2015-18)
  • Principal Investigator of NSABP for Cleveland Clinic (2013 to present)
  • Vice Chair, Research Review Committee, NSABP Foundation (2013-2016)
  • Member of Breast Cancer Working Group, NSABP (2010-2013)
  • Founding Editor of Bethesda Handbook of Clinical Oncology, Wolter Kluwer, Philadelphia (5th edition)
  • Chief Editor, Emerging Cancer Therapeutics, Demos, New York
  • Editor, Community and Supportive Care Oncology (Frontline Communications, NJ)
  • Editor, Breast Cancer Management and Treatment (London, U.K)
  • Associate Editor, ASCO Post (Harborside Press, NY)
  • Board of Directors, American Cancer Society, South Atlantic Division (2007-2010)
      • Editorial Board Member:
        • Journal of Breast Cancer Management, Future Science Group, London, U.K, Oncology and Biotechnology News, New Jersey, Expert Review of Anticancer Therapy, Future Science Group, London, U.K.
      • Manuscript Reviewer:
        • Lancet Oncology, Lancet
        • Journal of Clinical Oncology, ASCO
        • Clinical Cancer Research Focus, AACR
        • Human Bain Mapping
        • Expert Review of Immunotherapy
        • Clinical Breast Disease
        • British Journal of Cancer, Nature Publications Group
        • Annals of Saudi Medicine
        • Clinical Cancer Research, AACR
        • Expert Review of Anticancer Therapy
        • Cancer: American Cancer Society
        • Cancer Chemotherapy and Pharmacology


  • Internal Medicine - Medical Oncology

Specialty Interests

Breast Cancer treatment, Clinical Trials

Awards & Honors

  • Teacher of the Year Award: Oncology, Taussig Cancer Institute, Cleveland Clinic, 2016
  • Top Doctors in Cleveland 2014, 2015 and 2016 Cleveland Magazine
  • Top Cancer Doctors in U.S, Newsweek, 2015
  • U.S. News Top Doctor, Castle Connolly Medical Ltd, 2010 to 2016   
  • Selected to the Gold Human Honor Society (GHHS), 2011
  • “Pink Tie Guy” – Selected by Susan G. Komen for the Cure, WV 2010
  • Dean’s Award for Excellence in Clinical Medicine, School of Medicine, West Virginia University, 2010
  • Quality Award (Customer Satisfaction), West Virginia University Hospitals, 2006-2013
  • President of India, Her Excellency, Smt. Pratibha Patil “Vaidya Bhooshan”, by the Pazhassi Raja Trust, New Delhi, India, 2010
  • Bonnie Wells Wilson Eminent Scholar and Distinguished Professor in Breast Cancer Research, 2009
  • Outstanding Achievement in Medicine, Kerala Center, India League, New York, 2008
  • Outstanding Faculty Award, Department of Medicine, West Virginia University, 2007
  • STAR Award for customer service, West Virginia University Hospital, 2006
  • Clinician of the Year Award, Department of Medicine, West Virginia University, 2006
  • Volunteer of the Year Award for the state of West Virginia, American Cancer Society (ACS) 2006

Innovations & Patents

    1. Population Based Molecular Prognosis of Breast Cancer by Transcriptional Profiling by 28 Gene Assay, 2007 (Provisional Serial Number: 60/919,369
    2. Nonlinear Characterization of Breast Cancer using Multi-Compression 3D Ultrasound Elastography (Patent pending) Nonlinear Characterization of Breast Cancer using Multi-Compression 3D Ultrasound Elastography (Patent pending)


  • American Society of Clinical Oncology (ASCO)
  • American College of Physicians (ACP)
  • American Association of Cancer Research (AACR)
Research & Publications

Research & Publications

See publications for Jame Abraham, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 1/19/2018, Dr. Abraham has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Consulting and/or Speaking. Dr. Abraham receives fees of $5,000 or more per year as a paid consultant, speaker or member of an advisory committee for the following companies:

  • Gerson Lehrman Group
  • Elsevier

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

132 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
5 out of 5
Explains 4.9
Listens 5
Courtesy, Respect & Concern 4.9
Knows Medical History 5
Time Spent with Patient 5
Patient Rating of Doctor 5

15 Patient Comments

Reviewed on Oct 10, 2018

you couldn't ask for a better team than Dr Abraham and his nurse Nancy. I would give them a higher rating if possible.

Reviewed on Sep 6, 2018

I am very happy with the care I am receiving from Dr.Abraham & his nurse, Nancy

Reviewed on Aug 29, 2018


Reviewed on Aug 29, 2018

love dr abraham, when you are so scaredto know your results he walks in that door with a smile, you know you aregoing to be okay. very professional kind and compassionate for what you are goijg thru

Reviewed on Jul 18, 2018

Dr Abraham is the epitome of including the patient in joint decision making

Reviewed on Jun 28, 2018

Dr. Abraham is a wonderful doctor and his nurse who was with him was very nice and professional.

Reviewed on Jun 20, 2018

very goodDr. Abraham is a compassionate doctor.He makes sure you understand your care.

Reviewed on Jun 14, 2018

I had a great experience when I visited Dr. Abraham. He is the most kindest and caring physician ever! He explains everything carefully and is compassionate.

Reviewed on Jun 14, 2018

Dr. Abraham's nurse, Nancy, is the best! Very friendly and answers all my questions if Dr. Abraham is away from the office.

Reviewed on Jun 13, 2018

I can't say enough good things about Dr Abraham. I hope Cleveland Clinic does everything possible to keep him there.

Reviewed on Jun 7, 2018

Dr. Abraham is truly an amazing care giver and physician. He is professional and compassionate with his patients and I'm blessed to be one of them! cancer is terrifying but I feel confident in his care even when given difficult news. Dr. Abraham is psoitive, honest, sincere, smart and a wonderful part of the cancer care team.

Reviewed on May 23, 2018

I travel 4 hrs and 10 min just so I can keep Jane as my oncologist, so that says it all. I followed him to Cleveland Clinic from MBRCC. Jame is the most caring and understanding Dr. bar none, Cleveland Clinic is blessed to have him.

Reviewed on Apr 23, 2018

We really got our hope back after meeting Dr Jame and team...we know its a tough path ahead, but he gave us the courage to go ahead.

Reviewed on Mar 29, 2018

Dr. Abraham is an excellent oncologist with expertise in the field of breast cancer and he is also one of the kindest people I have ever met. From the moment we met he spent so much time getting to know me and my family and taking the time to explain all the areas of my treatment which would be needed to battle my cancer. He is such a caring, empathetic man and spends as much time as you need answering all of your concerns and questions. He called me on several occasions to check on how i was feeling, or talk about test results, or upcoming procedures. He has a gift for making you feel at ease and confident about your treatment plan at a very scary time in your life. He is an excellent leader of your oncology team and his empathy for his patients is an added bonus. I would highly recommend Dr. Jame Abraham to anyone who is diagnosed with breast cancer.

Reviewed on Mar 29, 2018

The cancer center runs very efficiently and there is little wait time to go into the exam room and very little wait time to see the physician. We call the clinic a very well oiled machine from top to bottom.

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