Department Mellen Center
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English
Surgeon No
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus

Specialties & Treatments

Treatment & Services

  • Consultation and Long-term Care
  • Lumbar Puncture (Spinal Tap)
View all 2 Treatment & Services +

Specialty in Diseases & Conditions

  • Acute Disseminated Encephalomyelitis (ADEM)
  • Devic's Disease (Neuromyelitis Optica)
  • Multiple Sclerosis
  • Neuroimmunology
  • Optic Neuritis
  • Transverse Myelitis
View all 6 Specialties +


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About Jeffrey Cohen, MD

Jeffrey Cohen, MD, has worked at Cleveland Clinic's Mellen Center for Multiple Sclerosis Treatment and Research since 1994 and became Director in 2014. Dr. Cohen has a large clinical practice devoted primarily to the care of patients with multiple sclerosis and related disorders. In addition, he is Director of the Experimental Therapeutics Program and has been involved in various capacities in a large number of clinical trials developing new therapies for multiple sclerosis. 

As Director of the Clinical Neuroimmunology Fellowship, he has trained over 30 fellows, many of whom have gone on to be prominent in the field. Dr. Cohen has served on a large number grant review committees, advisory groups and national and international task forces. He has over 180 publications concerning immunologic, clinical and research aspects of multiple sclerosis and is frequently invited to speak on these topics.
Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Hospital of the University of Pennsylvania
Philadelphia, PA USA

Residency - Hospital of the University of Pennsylvania
Philadelphia, PA USA

Internship - Hospital of the University of Pennsylvania
Internal Medicine
Philadelphia, PA USA

Medical Education - University of Chicago Pritzker School of Medicine
Chicago, IL USA

Undergraduate - Connecticut College
New London, CT USA

Professional Highlights

  • Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University
  • Director, Mellen Center
  • Director, Mellen Center Experimental Therapeutics Program
  • Director, Mellen Center Clinical Neuroimmunology Fellowship
  • Chair, International Advisory Committee on Clinical Trials, sponsored by National MS Society and ECTRIMS
  • President Elect, ACTRIMS 


  • Neurology

Specialty Interests

Clinical Trials, Multiple Sclerosis, Neuroimmunology

Awards & Honors

  • Freshman Chemistry Award, Connecticut College, 1973
  • Sophomore Zoology Award, Connecticut College, 1974
  • Junior Zoology Award, Connecticut College, 1975
  • Winthrop Scholarship Award, Connecticut College, 1975
  • Phi Beta Kappa, Connecticut College, 1976
  • Alpha Omega Alpha, University of Chicago, 1980
  • Clinician-Investigator Development Award, National Institute of Neurological Disorders and Stroke, 1988
  • Distinguished Alumnus, Connecticut College, 1994
  • American Neurological Association, 1998
  • Health Professional of the Year, Ohio Buckeye Chapter, National Multiple Sclerosis Society, 2001
  • Volunteer Hall of Fame, Health Professionals/Researchers, National Multiple Sclerosis Society, 2007
  • Best Doctors in America
  • Top Doctors, Cleveland Magazine
  • America’s Top Doctors, Castle Connolly

Innovations & Patents

  • Cohen JA, Greene MI, Williams WV, Inventors: Method of Stimulating Myelination of Cells, Patent No. 5,219,837.


  • American Academy of Neurology
  • American Neurological Association
Research & Publications

Research & Publications

See publications for Jeffrey Cohen, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 6/28/2019, Dr. Cohen has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Consulting and/or Speaking. Dr. Cohen receives fees of $5,000 or more per year as a paid consultant, speaker or member of an advisory committee for the following companies:

  • Convelo Therapeutics, Inc.
  • Mylan, Inc.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

49 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.5 out of 5
Explains 4.5
Listens 5
Courtesy, Respect & Concern 4.6
Knows Medical History 4
Time Spent with Patient 4.8
Patient Rating of Doctor 4.4

8 Patient Comments

Reviewed on Oct 3, 2019

my experience with dr Cohn and dr Cohen was beyond any expectation. the time spent with me, the questions ask, the suggestions for going forwarding with my multiple sclerosis was exceptional. simply put, I could not have been any more impressed. I will be changing my Columbus, Ohio provider to Dr. Cohen immediately. for the first time in a very very long time, I have hope moving forward with my MS. there are no words to express my gratitude for your exceptional staff.

Reviewed on Sep 30, 2019

I just transferred from out of state, and am accustomed to my provide being in the room for the entirely of my appointment. I did not like only have Dr. Cohen in the room for only 2-3 minutes and the end of my visit. I felt as though the assistant was the one to decide which information was important to share with my doctor, rather than me getting to do it.

Reviewed on Jun 13, 2019

Dr Macaron spent a very long time with me getting every detail of my illness and symptoms. She went above and beyond to help get my testing & other appointments scheduled together since we live 5 hours away. Her compassion & Care was so appreciated. Knowing that she & Dr Cohen are determined to figure out what is wrong with me gave me such HOPE.

Reviewed on Mar 28, 2019

We came to Cleveland Clinic with hopes that they would be able to give us a definitive diagnosis. I've had numerous tests done already and still don't know what's going on. I was disappointed that they feel the need for even MORE testing. The Dr. assured me that if I can just hang in there a couple more months and get this testing done that hopefully, they'll be able to piece it all together and give me a diagnosis.

Reviewed on Feb 21, 2019

My care provider has always included me in my care. He explains my health issues so that I'm able to understand. He's friendly and treats me as a person and always includes me in my care. I'd highly recommend him and have in the past.

Reviewed on Jan 15, 2019

the entire experiece was great. Dr Cohen was very helpful and kind. I can t say enough nice things about Dr. Cohen and Dr. Feng.

Reviewed on Dec 11, 2018

Everyone was so nice and accommodating. I had traveled from several states away just to get help from Dr Cohen. I was taken care of by all I came in co fact with in so many ways. I am anxiously awaiting a final verdict about what is going on with me so I can get back to life!!!! Thank you again so much!!

Reviewed on Nov 27, 2018

This was my first appointment with Dr. Cohen. He and his staff were wonderful!

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