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Department Mellen Center
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English
Surgeon No
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus

Specialties & Treatments

Treatment & Services

  • Long-Term Care
  • Lumbar Puncture (Spinal Tap)
View all 2 Treatment & Services +

Specialty in Diseases & Conditions

  • Acute Disseminated Encephalomyelitis (ADEM)
  • Devic's Disease
  • Multiple Sclerosis
  • Neuroimmunology
  • Optic Neuritis
  • Transverse Myelitis
View all 6 Specialties +


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About Jeffrey Cohen, MD

Jeffrey Cohen, MD, has worked at Cleveland Clinic's Mellen Center for Multiple Sclerosis Treatment and Research since 1994 and became Director in 2014. Dr. Cohen has a large clinical practice devoted primarily to the care of patients with multiple sclerosis and related disorders. In addition, he is Director of the Experimental Therapeutics Program and has been involved in various capacities in a large number of clinical trials developing new therapies for multiple sclerosis. 

As Director of the Clinical Neuroimmunology Fellowship, he has trained over 30 fellows, many of whom have gone on to be prominent in the field. Dr. Cohen has served on a large number grant review committees, advisory groups and national and international task forces. He has over 180 publications concerning immunologic, clinical and research aspects of multiple sclerosis and is frequently invited to speak on these topics.
Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Hospital of the University of Pennsylvania
Philadelphia, PA

Residency - Hospital of the University of Pennsylvania
Philadelphia, PA

Internship - Hospital of the University of Pennsylvania
Internal Medicine
Philadelphia, PA

Medical Education - University of Chicago Pritzker School of Medicine
Chicago, IL

Undergraduate - Connecticut College
New London, CT

Professional Highlights

  • Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University
  • Director, Mellen Center
  • Director, Mellen Center Experimental Therapeutics Program
  • Director, Mellen Center Clinical Neuroimmunology Fellowship
  • Chair, International Advisory Committee on Clinical Trials, sponsored by National MS Society and ECTRIMS
  • President Elect, ACTRIMS 


  • Psychiatry and Neurology - Neurology

Specialty Interests

Clinical Trials, Multiple Sclerosis, Neuroimmunology

Awards & Honors

  • Freshman Chemistry Award, Connecticut College, 1973
  • Sophomore Zoology Award, Connecticut College, 1974
  • Junior Zoology Award, Connecticut College, 1975
  • Winthrop Scholarship Award, Connecticut College, 1975
  • Phi Beta Kappa, Connecticut College, 1976
  • Alpha Omega Alpha, University of Chicago, 1980
  • Clinician-Investigator Development Award, National Institute of Neurological Disorders and Stroke, 1988
  • Distinguished Alumnus, Connecticut College, 1994
  • American Neurological Association, 1998
  • Health Professional of the Year, Ohio Buckeye Chapter, National Multiple Sclerosis Society, 2001
  • Volunteer Hall of Fame, Health Professionals/Researchers, National Multiple Sclerosis Society, 2007
  • Best Doctors in America
  • Top Doctors, Cleveland Magazine
  • America’s Top Doctors, Castle Connolly

Innovations & Patents

  • Cohen JA, Greene MI, Williams WV, Inventors: Method of Stimulating Myelination of Cells, Patent No. 5,219,837.


  • American Academy of Neurology
  • American Neurological Association
Research & Publications

Research & Publications

See publications for Jeffrey Cohen, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 7/10/2023, Dr. Cohen has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Consulting and/or Speaking. Dr. Cohen receives fees of $5,000 or more per year (or, in rare cases, equity or stock options) as a paid consultant, speaker or as a member of an advisory committee for the following companies:

  • FIND Therapeutics, Inc.
  • Convelo Therapeutics, Inc.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

40 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
5 out of 5
Explains 5
Courtesy, Respect & Concern 5
Patient Rating of Doctor 5

6 Patient Comments

Reviewed on Mar 11, 2024

Dr. Is very informative and takes time to explain things to you. To make sure all your questions are answered.

Reviewed on Jan 29, 2024

Dr. Cohen took the time to listen, explain, and answer my questions.

Reviewed on Sep 7, 2023

Dr. Cohen and Dr. Holloman both were amazing at calming my fears. They had the absolute best bedside manner and they took their time explaining everything to me.

Reviewed on Aug 17, 2023

Best care ever from the parking attendance to the doctors. Awesome experience

Reviewed on Jul 24, 2023

I saw Dr.Amin at first and he was very thorough, knowledgeable and pleasant.

Reviewed on Jul 20, 2023

I travel an hour to reach the facility and would travel even further if necessary. I have always been very happy with my care.

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