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Center for Reconstructive Transplantation

An unparalleled team of surgeons and physicians supported by basic and clinical research is bringing state-of-the-art care to patients with catastrophic disfigurement from disease or injury.

Becoming a Patient

Patients interested in being considered for reconstructive transplantation at Cleveland Clinic are carefully screened for psychological health, family support, understanding of complications and medication compliance.

Success Stories

Team Introduces Face Transplant Patient

Cleveland Clinic surgeons performed the first face transplant in the United States in December 2008.

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Patient is thriving one year after extraordinary surgery

Last December, a multi-disciplinary team of doctors and surgeons at Cleveland Clinic performed the first near-total face transplant in the United States. A year later, the patient – Connie Culp of Unionport, Ohio – can smell, taste and breathe normally. She had lost those abilities after a shotgun blast destroyed the middle part of her face in 2004. Read More

Saving Face

Maria Siemionow, MD, PhD, and a team of 30 specialists made medical history in December 2008 when they performed the first face transplant in the United States. Read More

Restoring Lives and Limbs

Researchers work to develop and deploy new methods for regenerating damaged bone, muscle and nerves. Read More

Near-total human face transplantation for a severely disfigured patient in the USA

July 18, 2009

The widely publicized milestone of Maria Siemionow, MD, PhD, and colleagues was recently detailed in The Lancet. The article describes the rationale and innovative procedures for the “tailored composite tissue allograft” for the woman who became the first U.S. patient to receive a near-total (80 percent) face transplant. Read More

About the Center for Reconstructive Transplantation

Our Team »

Cleveland Clinic has the most comprehensive reconstructive transplant team in the world.

Research »

By advancing scientific research in microsurgery and immuno-modulation, Cleveland Clinic is setting new standards of care.

Armed Forces Collaboration »

In partnership with Rutgers University and 15 other premier institutions, Cleveland Clinic is leading collaborative work to develop innovative medical therapies for the treatment of wounded solders.

Education »

The Center for Reconstructive Transplantation offers fellowships in microsurgery and research through Cleveland Clinic's comprehensive Education Institute. The program is designed to train surgeons, clinicians, researchers and ethicists in this burgeoning field. Learn more about educational opportunities.

Ethics »

Cleveland Clinic's commitment to advancing care includes a deep concern for the ethical implications of applying this new treatment to these vulnerable patients.

Philanthropy »

While reconstructive transplantation may offer the most promising solution to patients facing catastrophic loss of tissue, the procedures can be cost prohibitive to potential recipients.

Media Inquiries

Members of the media can call the Media Relations Department at: 216.444.0141