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When your hormones are out of balance, your body often tells you in some not-so-pretty ways.

Acne, weight gain and excess facial and body hair are a few of the physical effects of polyendocrine metabolic ovarian syndrome. But so are things you can’t see, like irregular periods and struggles with fertility. If you’re one of the countless people with this condition, you know how frustrating it can be. It can feel like your body’s turning on you, and you don’t know how to get things back on track.

Polyendocrine metabolic ovarian syndrome (PMOS) — previously called polycystic ovary syndrome — is a lifelong condition. But there are ways to control the symptoms that can get in the way of your life. Our compassionate providers are ready with treatment options and strategies that can help you manage your condition and live your life with confidence.

Why Choose Cleveland Clinic for Polyendocrine Metabolic Ovarian Syndrome Care?

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Specialized knowledge:

Our providers are board-certified and fellowship-trained experts. Your PMOS care team may include gynecologists, endocrinologists and dietitians. Meet our team.

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Collaborative care:

PMOS can affect your whole body, not just your reproductive system. Our specialists work as a team with other Cleveland Clinic experts to make sure you get the comprehensive care you need to start feeling better.

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Caring approach:

We understand that the physical effects of PMOS can cause anxiety and sometimes even depression. Our providers want you to feel good about yourself again, and we’re here to support your physical and mental health.

Diagnosing Polyendocrine Metabolic Ovarian Syndrome at Cleveland Clinic

We want to know how PMOS is affecting you. We’ll ask about your symptoms and how they impact your life. From the start, we want to understand your worries and the challenges that go with your PMOS. Learning about your personal and family health history will also help us learn about you. Our goal during this first part of the diagnosis process is to get to know you. This will also include testing. Running tests helps us learn about your hormones, ovaries and overall health. These tests may include:

  • Pelvic examination: Your provider inserts a speculum (an instrument that expands your vaginal walls) into your vagina to take a close look at your cervix. They also put their hands on your abdomen and pelvis to feel your uterus and ovaries.
  • Blood test: We take a blood sample and send it to our lab, where we check your hormone levels. Too much androgen (a male hormone) is a sign of PMOS. And because PMOS can also be a sign of diabetes and heart disease, we’ll check your blood sugar and cholesterol levels, too.
  • Ultrasound: We use transvaginal pelvic ultrasound to see if you have cysts on your ovaries and to check your uterus. Your healthcare provider puts a transducer (thin probe) covered with a special plastic sleeve and gel into your vagina. This simple test uses soundwaves to create 2D and 3D pictures of your pelvic organs, which helps our specialists to see if you have polycystic ovaries.

Locations

We offer treatment for polyendocrine metabolic ovarian syndrome at many locations throughout Ohio, Florida and London.

Treating Polyendocrine Metabolic Ovarian Syndrome at Cleveland Clinic

Everyone with PMOS has different concerns and priorities, so before designing a treatment plan, our specialists want to understand exactly what yours are. For example, you may want to:

  • Become pregnant
  • Get rid of excess hair growth
  • Lose weight
  • Regulate your periods

You may want all of the above — and that’s OK, too. Our experts work together across teams and departments to treat everything about this condition that’s holding you back. Once we understand your individual goals, we’ll come up with a treatment plan to make your PMOS more manageable. This may include:

  • Lifestyle counseling: We make sure you have the information you need to live a healthy life. Our dietitians can teach you how to make changes to your diet to help control blood sugar, cholesterol and weight gain. We can also help you start a manageable exercise program.
  • Hormonal medications: We may recommend birth control medications containing estrogen and progestin. These medications can help reduce hair growth, regulate your periods and lower your risk of developing endometrial cancer.

PMOS and fertility

If you have PMOS, you may not ovulate (release eggs) every month. And if you want to become pregnant, this can be a problem. Our specialists work with you to help you reach your goal of becoming pregnant.

To help your ovaries release an egg, Cleveland Clinic’s gynecologists may recommend medications to help increase your fertility, depending on your health and history.

What’s Next?

Living with PMOS can be frustrating and discouraging, but it’s easier to handle when the right healthcare team is supporting you along the way. If you’ve been diagnosed with PMOS or are wondering if you might have it, reach out to a provider as soon as possible. We’re here to help you learn how to manage your PMOS, which is the first step toward living a happy, healthy life with this condition.

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