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As you get older, chances are your vision will change. But if you’re seeing blank or dark spots in the center of your vision, it’s time for an eye exam.

These changes are common signs of age-related macular degeneration (AMD) — the leading cause of vision loss in people ages 50+. It affects your central vision so you can’t always see people or things right in front of you. And this can likely feel a bit unnerving.

At Cleveland Clinic, we understand how vision problems like AMD can change your life. We’re here to help you find out what’s going on. And we’ll guide you through a personalized treatment plan designed to help you keep your vision for as long as possible.

Why Choose Cleveland Clinic for Macular Degeneration Care?

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Specialized knowledge:

Each eye care expert at Cleveland Clinic has years of experience and in-depth training. They specialize in diagnosing and treating specific eye conditions, including macular degeneration, using the latest testing and therapies. Meet our team.

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Innovation and research:

Our experts never stop searching for new breakthroughs to prevent and treat eye conditions and vision loss. We lead clinical trials and research of new and emerging therapies to treat macular degeneration and other vision problems.

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Collaborative care:

Some underlying health issues can also damage your eyes and cause vision loss. Our team works together with other specialists to find out what’s causing your vision problems to make sure you get the right treatment.

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Caring approach:

Every aspect of the care you get at Cleveland Clinic keeps your needs and goals in mind. We want your diagnosis, treatment and follow-up journey to be as convenient and comfortable as possible.

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National recognition:

Cleveland Clinic is a trusted healthcare leader. We're recognized in the U.S. and throughout the world for our expertise and care.

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Virtual visits:

Not all appointments need to be in person. Virtual visits let you meet one-on-one with your providers using a smartphone, tablet or computer. You can talk with them about your progress and concerns from the comfort of home.

Macular Degeneration Diagnosis at Cleveland Clinic

Age-related macular degeneration is a leading cause of vision loss. It affects the macula at the back part of your retina. The macula controls your central vision — or the things directly in front of you.

AMD has three stages — early (macula changes without vision loss), intermediate (things might seem blurry or wavy) and late (you lose your central vision). Often, your routine eye care provider may find signs of this retinal disease during your annual eye examination.

There are two different types of macular degeneration, which can develop in one or both eyes.

  • Dry macular degeneration: In dry (atrophic) AMD, the macula becomes thinner, causing gradual vision loss. This is the most common type of AMD.
  • Wet macular degeneration: In wet (exudative) AMD, blood vessels at the back of your eye grow in ways they shouldn’t. They damage the macula, quickly causing vision loss.

Our healthcare providers are familiar with all stages and types of macular degeneration and will work with you to pinpoint what’s causing your vision issues. Then, they’ll craft the most personalized treatment plan for your needs and goals.

What to expect at your first visit

At Cleveland Clinic, you’ll work with our experienced ophthalmologists. They’ll lead a care team of other skilled healthcare providers — like surgeons, nurse practitioners and physician assistants — to make sure you get expert, personalized care.

At your first visit, your providers will sit down and get to know you. They’ll ask what kind of symptoms you’ve been having and how long they’ve been happening. They’ll also ask you about your medical history and do a thorough eye examination to check for changes to your retina or macula.

During this exam, we’ll have you do a test where you look at a grid of straight lines and ask you if you see any sections of the grid that look blurry, wavy or broken. This is called an Amsler grid test. We’ll also use eye drops to widen (dilate) your pupils so we can use a special lens to look deeper into your eyes and check your retina.

Diagnostic testing

After your eye exam, you’ll likely have a number of specialized tests so we can make a solid diagnosis. These tests could include:

  • Fluorescein angiogram (FA): We inject a yellow dye (fluorescein) into your arm to make your blood vessels more visible. We use a special camera to see if abnormal vessels have formed and if dye leaks from them into the macula.
  • Optical coherence tomography (OCT): We use this high-resolution optical coherence tomography to take pictures of the back of your eye, including your retina and macula.
  • Optical coherence tomography angiography (OCTA): In this test, we use laser light reflection instead of dye to get 3D images of how blood flows through your eye.


Our healthcare providers see patients at convenient locations throughout Northeast Ohio.

Macular Degeneration Treatment at Cleveland Clinic

If we learn you do have macular degeneration, we’ll create a personalized treatment plan to help you manage your condition and slow vision loss. Your treatment options will depend on the type and stage of AMD you have.

Treating dry AMD

If you have dry AMD, your provider may recommend nutritional supplements, like the AREDS 2 vitamins — which include vitamins C and E, copper, zinc and lutein — to help slow your vision loss. Regular exercise and quitting smoking can also help your eyes stay healthier.

Treating wet AMD

Our ophthalmologists can help slow vision loss associated with wet AMD using:

  • Anti-vascular endothelial growth factor (anti-VEGF) injections: Specialists inject medication to prevent the growth of abnormal blood vessels in your eye.
  • Photodynamic therapy: In photodynamic therapy (PDT), experts inject you with a drug that interacts with light. They use lasers to cause a chemical reaction and destroy the blood vessels that cause wet AMD.

Taking the Next Step

When you’re diagnosed with macular degeneration, you’ll face changes as your central vision decreases. You may not be able to easily recognize faces, read as well as you used to or even drive. We know how frustrating this can be. That’s why we offer more than medical treatment. When you come to Cleveland Clinic, you have an instant support team of caring providers to help you and your family understand and manage the changes that come hand-in-hand with macular degeneration. We’re here for you, every step of the way.

Getting an appointment with Cleveland Clinic’s macular degeneration experts is easy. We’ll help you get the care you need.


Getting an appointment with Cleveland Clinic’s macular degeneration experts is easy. We’ll help you get the care you need.

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