Details

Details

Title Integrated 3D x-ray and ultrasound Guided Radiation Therapy of Soft Tissue Target

IRB CASE6Y14

CC 15-465

Hospital Main Campus

Disease GI (Gastrointestinal), Liver, Pancreas, Prostate

Description

Description

Purpose of this protocol is to investigate the feasibility of combining on-board CBCT with ultrasound imaging to overcome the shortcomings of CBCT or ultrasound imaging alone for imaging guided radiotherapy delivery. Specifically, we will investigate (a) whether the ultrasound imaging can enhance soft tissue tumor localization; (b) whether the presence of a passive arm is interfering radiation delivery during each treatment; (c) whether the presence of the ultrasound probe will affect the choice of radiation beams and degrade treatment plan quality.

Inclusion Criteria

Inclusion Criteria

  • The patient must have either 1) an established diagnosis of pancreatic cancer by biopsy or 2) cancer involving the liver by biopsy or radiographic criteria, or 3) prostate cancer by biopsy, with the intent of undergoing definitive dose radiation therapy to targets within the pancreas, liver, or prostate. Patients with prostatectomy receiving post-operative radiotherapy are also eligible.
  • Age > 18 years.
  • Performance status - Karnofsky PS ≥ 70
  • Subjects must have the ability to understand and the willingness to sign a written informational form.
Exclusion Criteria

Exclusion Criteria

  • Patients with uncontrolled inter-current illness or psychiatric illness/social situations that would limit compliance with study requirements