The Lou Ruvo Center for Brain Health’s clinical trials program is among the largest in the country for Alzheimer’s disease. We have conducted more than 80 trials in Huntington’s and Parkinson’s disease, MS, Alzheimer’s disease, frontotemporal and Lewy body dementia, memory decline and normal cognition. Additionally, we offer investigator-led studies, including a study of repeated head trauma in active and retired professional fighters.
Hollywood often portrays research as a dramatic “Eureka!” moment when a single scientist working in his lab jumps to his feet, bubbling test tube in hand, and announces he has found a miracle cure. In real life, research is far more complex, yielding results after years, not moments, of investigation. The cornerstone is clinical trials, the only route to advance new drug therapies.
Almost every staff member at Cleveland Clinic Lou Ruvo Center for Brain Health is involved in conducting clinical trials. These trials generate the only type of data acceptable to the Food and Drug Administration (FDA) when it considers which treatments to approve for people with brain disorders.
Neuroscience research does not occur in a vacuum. Our center takes part in multidisciplinary, multisite trials sponsored by multiple stakeholders, including pharmaceutical companies, biotechnology companies, and independent foundations and donors.
We also engage with and lead important national and international neuroscience networks, among them the Alzheimer’s Disease Neuroimaging Initiative (ADNI), the Global Alzheimer’s Platform (GAP) and the Parkinson’s Study Group (PSG). We have been named:
- National Multiple Sclerosis Society Partner in MS Care
- Lewy Body Dementia Association Research Center of Excellence
- Parkinson’s Foundation Center of Excellence
- CurePSP Center of Care
All We Need Is You
Patients are the vital link in research. When you participate in a clinical trial, you become a citizen scientist, making important contributions toward identifying new therapies to help yourself and countless others who may be affected.
You can also help by supporting our impact at Cleveland Clinic Nevada. Research is very expensive and your donation, no matter the size, can help our center fulfill its mandate to investigate the next generation of drug therapies for brain disease.
Participate in a Clinical Trial
What are Clinical Trials?
Clinical trials are one of the cornerstones to advances in therapy. The most cutting-edge and promising therapies are tested in a safe, comfortable and ethical manner.
Patients have the opportunity to participate in these advancements and to participate in new therapies before they become commercially available. A clinical trial consortium links our Cleveland, Florida and Nevada sites to ensure that patients have access to clinical trials regardless of where they are treated.
There are many types of clinical trials spanning treatment, diagnosis, prevention, screening, observation and quality of life. Clinical trials are a required step toward FDA approval of new drugs, and thus are the only way to find new treatments or a cure for brain disease.
We’re looking for people who represent the rich diversity of our Nevada communities. You can help.Why Should I Get Involved?
- To contribute to the effort of finding more effective treatments for neurological disease.
- To gain access to potential treatments before they are widely available.
Aaron Ritter, MD, Director of Clinical Trials at Cleveland Clinic Lou Ruvo Center for Brain Health
How do I participate in a clinical research study?
Your participation in clinical research could make a difference for your family and your community. We offer opportunities to participate in research regardless of where you receive neurological care. Some research studies need healthy volunteers, too.
Are you ready to join a study? Please tell us more about you so we can find a study right for you! Register for Research
Research for Alzheimer's Disease (NVeADRC)
In September 2020, the National Institute on Aging (NIA) at The National Institutes of Health awarded Cleveland Clinic Lou Ruvo Center for Brain Health $3.3 million to establish The Nevada exploratory Alzheimer’s Disease Research Center (NVeADRC).
We are among the first cohort of centers nationally to receive this exploratory award and hold the distinction as the first and only NIA-funded Alzheimer’s Disease Research Center in Nevada. The NVeADRC will help meet a great need here in our state as well as in the scientific community by focusing on disparities faced by individuals with dementia in rural settings.
Leveraging our geographic status as a Frontier State, the NVeADRC will develop novel methodologies and technology to enroll patients from rural communities throughout Nevada into a cohort and collect high-quality data to advance the mission of the ADRC Program.
The three-year award is the first of its kind to be presented as part of the NIH’s prestigious Alzheimer’s Disease Research Centers Program – a national network of researchers and clinicians at major medical institutions pursuing improved diagnosis and care for people with Alzheimer’s disease.
Email our team at [email protected] for more information on the NVeADRC.
Brain Health Research Programs in Las Vegas
Cleveland Clinic Lou Ruvo Center for Brain Health is dedicated to better understanding of brain diseases and the development of more effective treatments for Alzheimer’s disease, frontotemporal dementia, Lewy body dementia and mild cognitive impairment; Parkinson’s and Huntington’s disease and other movement disorders; and multiple sclerosis.
The center participates in several research studies and clinical trials to advance new treatments and diagnostic approaches for patients, including repurposing drugs approved for other conditions to treat neurodegenerative disorders, leveraging imaging techniques such as MRI, investigating physical activity to slow the advance of disease, and using bioinformatics and clinical data to understand dementia, neuroinflammation, and repetitive head trauma.
Choose a Research Program
- Alzheimer’s Disease: Repurposed Agents
- Dementia with Lewy Bodies
- Neurodegenerative Diseases: Las Vegas Clinical Trials
- Neurodegenerative Diseases: Advancing Neuroimaging Techniques
- Repetitive Head Trauma: Effects in Football and Professional Combat Sports
- Dementia: Integrating Cognition, Imaging, and Modern Data Science
Contact our Research Team
Email: Email the Las Vegas research team