A VQ scan is a two-part test that healthcare providers most commonly use to diagnose a blood clot in your lungs (pulmonary embolism). It measures the airflow (ventilation) and blood flow (perfusion) in your lungs. You receive safe radioactive material as a gas and an injection while a provider takes pictures of your lungs.
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A VQ scan is an imaging test that evaluates how well air and blood flow through your lungs. Healthcare providers most commonly use it to detect a blood clot in your lungs. They may also use it to diagnose certain types of pulmonary hypertension (high blood pressure in your lungs) and to check your lung function:
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A VQ scan is a two-part, noninvasive test. The “V” stands for ventilation, or air flow in and out of your lungs. The “Q” stands for quantity of perfusion, or blood flow to the small blood vessels in your lungs. You might also hear this test called a ventilation-perfusion scan, a lung scan or lung scintigraphy.
Unlike CT scans, VQ scans don’t use contrast dye. So, they’re safe for people who can’t use contrast due to allergies or renal insufficiency. VQ scans do use a small amount of radiation.
A healthcare provider performs a VQ scan in two parts. These happen one right after another on the same day. For the first part (ventilation), your provider will have you breathe in a small amount of radioactive particles (tracer).
Think of the tracer like bright tags attached to parts of the air. Your provider uses a special camera — similar to an X-ray or a CT camera — to take pictures of your lungs. The bright tags of the tracer make the air flowing into your lungs show up on the images.
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For the second part (perfusion), your provider will give you an injection of a similar tracer. This time, the bright tags flow through your blood vessels. Your provider will use the same camera to get pictures of the blood flow in your lungs.
You don’t need to do anything specific to prepare for a VQ scan. But you should tell your provider:
Before you get a VQ scan, you’ll get a chest X-ray. This can be anywhere from one to 24 hours before your scan. This gives your provider more information to help them understand the scan results.
You’ll start with the ventilation scan. During this part:
In most cases, you’ll move to the perfusion scan immediately after the ventilation scan. The two are very similar and have many of the same steps. Instead of breathing in the radioactive tracer, your provider will inject the tracer into your vein using an IV.
A VQ scan takes between 30 and 60 minutes in total. Each test takes about 15 minutes. Yours may take more or less time depending on prep time and whether your provider is getting the images they need.
After a VQ scan, the tracer will leave your lungs as you breathe in fresh air. The injected tracer will lose its radioactivity and leave the rest of your body through your pee and poop in a few hours or days. If you’re breastfeeding, check with your provider about how to safely feed your baby for the day or two following the scan.
The risks of having a VQ scan are minimal. They include:
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You’ll usually know the results of a VQ scan within 24 hours. If the results are abnormal, it means something is preventing your lungs from working properly. If the sets of pictures from the two parts of the scan don’t match, it could mean you have a pulmonary embolism (PE).
| Terms you might see on a scan report: | What they mean: |
|---|---|
| Normal, Low probability, PE absent, No evidence of PE | Your images show you have normal air and blood flow in your lungs, or your chance of a blood clot is low. |
| Intermediate probability, Indeterminate probability, Non-diagnostic | There’s a possibility that you have a blood clot, but it couldn’t be determined based on these images. You might need more tests. |
| High probability, PE present, PE-positive | Based on the scans, it’s likely that you have a blood clot. Your provider will talk to you about your treatment options. |
| Terms you might see on a scan report: | |
| Normal, Low probability, PE absent, No evidence of PE | |
| What they mean: | |
| Your images show you have normal air and blood flow in your lungs, or your chance of a blood clot is low. | |
| Intermediate probability, Indeterminate probability, Non-diagnostic | |
| What they mean: | |
| There’s a possibility that you have a blood clot, but it couldn’t be determined based on these images. You might need more tests. | |
| High probability, PE present, PE-positive | |
| What they mean: | |
| Based on the scans, it’s likely that you have a blood clot. Your provider will talk to you about your treatment options. |
Talk to your healthcare provider if you have any questions about the test or its results.
CT scans and VQ scans both take pictures of your lungs to help diagnose issues like blood clots. A CT scan uses a camera that takes pictures of a contrast dye in your body. A provider looks at the pictures to identify issues.
A VQ scan uses a camera that takes pictures of radioactive particles in your body. A provider can look at one set of pictures or compare the two to understand how your lungs are working. It exposes you to less radiation than a CT scan.
Blood clots can be life-threatening. When every second counts, a VQ test is a low-risk, noninvasive way for a healthcare provider to quickly make a diagnosis so you can be treated. But let your provider know if you’re pregnant or think you could be pregnant. They may recommend a different type of test to look for lung issues.
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Cleveland Clinic’s health articles are based on evidence-backed information and review by medical professionals to ensure accuracy, reliability and up-to-date clinical standards.
Cleveland Clinic’s health articles are based on evidence-backed information and review by medical professionals to ensure accuracy, reliability and up-to-date clinical standards.
Goldhaber SZ. Deep-Venous Thrombosis and Pulmonary Thromboembolism. In: Longo DL, Fauci AS, Kasper DL, et al., eds. Harrison's Principles of Internal Medicine. 22nd ed. McGraw Hill; 2025.
Metter D, Tulchinsky M, Freeman LM. Current Status of Ventilation-Perfusion Scintigraphy for Suspected Pulmonary Embolism (https://pubmed.ncbi.nlm.nih.gov/28095020/). AJR Am J Roentgenol. 2017 Mar;208(3):489-494. Accessed 7/7/2026.
Wang RC, Miglioretti DL, Marlow EC, et al. Trends in Imaging for Suspected Pulmonary Embolism Across US Health Care Systems, 2004 to 2016 (https://pubmed.ncbi.nlm.nih.gov/33216141/). JAMA Netw Open. 2020 Nov 2;3(11):e2026930. Accessed 7/7/2026.
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