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Percutaneous Nephrolithotomy

Medically Reviewed.Last updated on 03/03/2026.

Percutaneous nephrolithotomy is a surgical procedure to remove kidney stones that are too large to pass on their own or don’t respond to other treatments. The procedures takes three to four hours to complete. Risks include blood in your pee, blood clots, infection and healing problems. Recovery takes two to four weeks.

What Is a Percutaneous Nephrolithotomy?

When nothing else works to treat kidney stones, we turn to percutaneous nephrolithotomy. Learn how this surgery works, what to expect and its risks.

Percutaneous nephrolithotomy (PCNL) is surgery to remove kidney stones that are too large to pass on their own. Healthcare providers usually suggest a percutaneous nephrolithotomy (per-kew-TAY-nee-us NEF-ro-leh-THOT-oh-mee) when other kidney stone treatments don’t work or aren’t possible.

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“Percutaneous nephrolithotomy” is a big word. But what does it mean? “Percutaneous” means that the procedure occurs through the skin. “Nephrolithotomy” means the removal of a calculus (another word for a kidney stone) from a kidney.

Is it a major surgery?

PCNL is a minimally invasive surgery. That means it:

  • Has fewer complications
  • Has less impact on your body
  • Allows you to heal faster than open surgery

But it’s still a major surgery that’s more invasive than other kidney stone treatments.

How common is this procedure?

Percutaneous nephrolithotomy is a common treatment for large kidney stones. The best candidate for PCNL is someone who:

Your provider will review all of your options with you. Together, you’ll reach a shared decision regarding your treatment goals and outcomes.

Procedure Details

How should I prepare for a percutaneous nephrolithotomy?

Before the procedure, you’ll meet with your healthcare provider. They’ll:

  • Check your general health
  • Take your vital signs (temperature, pulse and blood pressure)
  • Ask about any prescription or over-the-counter medications you’re taking that may increase your risk of bleeding
  • Ask about any allergies you have

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They may also recommend imaging tests (CT scan, ultrasound, X-ray) to get a better view of the kidneys and the stone.

Your provider will also give you specific directions on eating and drinking. You shouldn’t eat or drink anything after midnight the night before your surgery. If you must take medications, you should take them with a small sip of water.

What happens during the procedure?

A special team of healthcare providers will perform percutaneous nephrolithotomy. The team typically includes:

  • A urologist
  • An anesthesiologist
  • Nurses
  • Surgical technicians

During most PCNL procedures, you’ll lie on your stomach (prone). This allows your urologist to access your kidney through your back. But sometimes, urologists place you in other positions. They may place you on your back (supine) or on your back with a cushion under your flank (modified supine).

Your anesthesiologist will put you under with general anesthesia. You won’t be awake, won’t move and won’t feel any pain during the procedure.

During the PCNL, your urologist will:

  • Make a small (about half an inch or 1 cm) incision
  • Insert a protective sleeve through the incision and into your kidney
  • Insert a small video camera (nephroscope) into the sheath to locate and remove the kidney stone

In some cases, your urologist may use a laser or shock-wave device (lithotripter) to break the stone into smaller pieces before taking it out. They may also insert a drainage tube or ureteral stent. These help drain pee and promote healing.

PCNL usually takes two to four hours to complete.

What happens after the procedure?

After PCNL, healthcare providers will:

  • Move you to a recovery room
  • Monitor your overall health
  • Treat your pain
  • Give you recovery instructions

They may also send the kidney stone to a lab. Lab technicians will figure out what’s in your kidney stone. Identifying what makes it up can help determine its cause. This can prevent new stones from forming.

Most people need to stay in the hospital for one day after surgery. This allows providers to make sure you’re recovering as expected, starting to heal and not having any issues with managing your pain.

You may have small amounts of blood in your pee for a week or two after PCNL. This is normal.

Risks / Benefits

What are the benefits of percutaneous nephrolithotomy?

The main advantage of the procedure is that it removes kidney stones that are too big to pass on their own or respond to other treatments. It’s also a minimally invasive procedure. That means you’ll heal faster than with open surgery.

How successful is the procedure?

The PCNL success rate is good. The success rate is about 75% to 98%.

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What are the risks or complications?

All surgeries have risks, even minimally invasive procedures. Some percutaneous nephrolithotomy risks include:

  • Anesthesia risks
  • Healing problems
  • Infection
  • Mass of clotted blood (hematoma)
  • Blood clots
  • Fluid buildup at the surgical site (seroma)
  • Kidney damage
  • Sepsis or a complicated urinary tract infection (UTI)
  • Inability to remove the kidney stone or need for additional procedures

For most people, the procedure is moderately painful. Your healthcare provider may prescribe pain relievers. If you have a drainage tube, your pain should go down after your provider removes it. Sometimes, the ureteral stent is the most painful part of the procedure.

Recovery and Outlook

What is the recovery time?

Your body is unique, so recovery times may vary. But in general, most people recover two to four weeks after percutaneous nephrolithotomy.

As you recover, it’s important to avoid strenuous physical activity. This includes heavy lifting. Don’t lift anything heavier than a gallon of water (about 8.5 pounds) for at least two weeks.

When can I go back to work/school?

Most people can return to work or school about a week after PCNL.

If you have a more physically demanding job, it’s a good idea to take at least two weeks off work.

When To Call the Doctor

When should I call my healthcare provider?

Schedule a checkup with your healthcare provider four to six weeks after your PCNL.

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Call your healthcare provider right away if you have any complications. These may include:

  • Heavy bleeding or discolored drainage at your incision site
  • Blood clots, which look like ketchup
  • Dark blood in your pee
  • A fever of 100 degrees Fahrenheit (38 degrees Celsius) or higher
  • Signs of infection, including fever, chills, headache or a bad odor around your surgical site
  • Skin separation at your stitches
  • Increased pain

A note from Cleveland Clinic

Kidney stones can cause a lot of pain. They can be even more frustrating if they’re large or oddly shaped — they may not pass on their own, and they may be too big for simpler treatments. But a percutaneous nephrolithotomy is a relatively safe and effective procedure for removing stubborn stones.

Talk to your healthcare provider about any concerns. They’ll answer any questions and go into greater detail about the procedure, including all possible outcomes and risks.

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Medically Reviewed.Last updated on 03/03/2026.

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References

Cleveland Clinic’s health articles are based on evidence-backed information and review by medical professionals to ensure accuracy, reliability and up-to-date clinical standards.

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Kidney stones can be a painful interruption in your busy life. At Cleveland Clinic, we’ll craft a treatment plan that works for you.

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