Motixafortide Injection

What is this medication?

MOTIXAFORTIDE (moe TIX a FOR tide) helps prepare your body before a stem cell transplant. It works by helping your bone marrow make and release stem cells into the blood.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): APHEXDA

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

• Leukemia
• An unusual or allergic reaction to motixafortide, other medications, foods, dyes, or preservatives
• Pregnant or trying to get pregnant
• Breastfeeding

How should I use this medication?

This medication is injected under the skin. It is given by your care team in a hospital or clinic setting.

Talk to your care team about the use of this medication in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

This does not apply.

What may interact with this medication?

Interactions are not expected.

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Your condition will be monitored carefully while you are receiving this medication.

You may need blood work while you are taking this medication.

Talk to your care team if you may be pregnant. Serious birth defects can occur if you take this medication during pregnancy and for 8 days after the last dose. You will need a negative pregnancy test before starting this medication. Contraception is recommended while taking this medication and for 8 days after the last dose. Your care team can help you find the option that works for you.

Do not breastfeed while taking this medication and for 8 days after the last dose.

What side effects may I notice from receiving this medication?

Side effects that you should report to your care team as soon as possible:

• Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
• High white blood cell level—fever, fatigue, trouble breathing, night sweats, change in vision, weight loss

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

• Back pain
• Flushing
• Itching
• Nausea
• Numbness, decrease in sense of touch or sensation
• Numbness or tingling of the tongue or mouth
• Pain, redness, or irritation at injection site

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

This medication is given in a hospital or clinic. It will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.