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METHYLENE BLUE (METH uh leen bloo) is a dye that is used in certain diagnostic procedures.
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Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
COMMON BRAND NAME(S): Urolene Blue
They need to know if you have any of these conditions:
•cyanide poisoning
•glucose-6-phosphate dehydrogenase (G6PD) deficiency
•kidney disease
•an unusual or allergic reaction to methylene blue, phenothiazines, thiazide diuretics, other medicines, foods, dyes, or preservatives
•pregnant or trying to get pregnant
•breast-feeding
Take this medicine by mouth with a full glass of water. Follow the directions on the prescription label. Take after meals. Take your doses at regular intervals. Do not take your medicine more often than directed.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Do not take this medicine with any of the following medications:
•bupropion
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•certain medicines for depression or anxiety
•clomipramine
•doxepin
•duloxetine
•fluoxetine
•MAOIs like Marplan, Nardil, and Parnate
•milnacipran
•mirtazapine
•rasagiline
•selegiline
•St. John's wort
•trazodone
•tryptophan
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
Visit your doctor or health care professional for regular checks on your progress.
Side effects that you should report to your doctor or health care professional as soon as possible:
•bladder irritation
•fever
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
•blue-green coloration of urine and stools
•diarrhea
•nausea, vomiting
•skin discoloration
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from moisture and light. Throw away any unused medicine after the expiration date.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
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Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.