Tromethamine Solution for Injection

What is this medication?

TROMETHAMINE makes blood and urine more alkaline or less acidic. It is used to treat metabolic acidosis, a condition where the body produces too much acid or when the kidneys are not removing enough acid from the body.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Tham

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

• kidney disease
• respiratory acidosis
• salicylate toxicity in a newborn
• an unusual or allergic reaction to tromethamine, other medicines, foods, dyes, or preservatives
• pregnant or trying to get pregnant
• breast-feeding

How should I use this medication?

This medicine is for infusion into a vein. It is given by a health care professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

This does not apply.

What may interact with this medication?

This medicine may interact with any of the following medications:

• amphetamines like amphetamine, dextroamphetamine, lisdexamfetamine, methamphetamine
• lithium
• norfloxacin

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Your condition will be monitored carefully while you are receiving this medicine.

What side effects may I notice from receiving this medication?

Side effects that you should report to your doctor or health care professional as soon as possible:

• confusion
• dark urine
• fast heartbeat
• general ill feeling or flu-like symptoms
• light-colored stools
• pain, redness, or irritation at site where injected
• right upper belly pain
• sweating
• unusually weak or tired
• yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• dizziness
• feeling anxious
• increased hunger
• loss of appetite, nausea

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

Keep out of the reach of children.

This drug is given in a hospital or clinic and will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.