Pyridostigmine tablets, regular release

What is this medication?

PYRIDOSTIGMINE (peer id oh STIG meen) can help with muscle strength. It is used to treat myasthenia gravis.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Mestinon

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

•asthma

•difficulty passing urine

•heart disease

•infection in abdomen, peritonitis

•irregular, slow heartbeat

•kidney disease

•seizures

•stomach or bowel obstruction or ulcers

•thyroid disease

•an unusual or allergic reaction to pyridostigmine, bromides, other medicines, foods, dyes, or preservatives

•pregnant or trying to get pregnant

•breast-feeding

How should I use this medication?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take your medicine at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on your doctor's advice.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medication?

Do not take this medicine with any of the following medications:

•other medicines for myasthenia gravis like neostigmine

•quinine

This medicine may also interact with the following medications:

•atropine

•bethanechol

•disopyramide

•edrophonium

•guanadrel

•guanethidine

•mecamylamine

•medicines that block muscle or nerve pain

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Visit your doctor or health care professional for regular checks on your progress. Tell your doctor if your symptoms do not improve or if they get worse.

Wear a medical ID bracelet or chain, and carry a card that describes your disease and details of your medicine and dosage times.

What side effects may I notice from receiving this medication?

Side effects that you should report to your doctor or health care professional as soon as possible:

•allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

•breathing problems

•changes in vision

•muscle cramps, spasm

•slow or irregular heartbeat

•stomach cramps, pain

•unusually weak or tired

•vomiting

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

•diarrhea, especially at start of treatment

•increased saliva

•increased sweating

•nausea

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep container tightly closed. Throw away any unused medicine after the expiration date.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.