Group C strep (strep C) is a set of Streptococcus bacteria. It most commonly causes sore throats or skin infections. But it can also infect other parts of your body, like your bones or heart. Infections can range from mild to severe and can sometimes be hard to treat. Healthcare providers treat group C strep infections with antibiotics.
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Group C strep (strep C) is a set of several types of Streptococcus bacteria that can sometimes make you sick. It most commonly causes a sore throat or skin infections. But sometimes, it can cause infections deep in your body, like in your bones or heart.
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Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy
Group C strep sometimes naturally lives on your skin or in your throat, where it doesn’t usually hurt you. But if it gets inside your body or grows out of control, it can make you sick.
Types of group C strep infections include:
Many people have strep C in their throats without getting sick. So, it’s not clear if strep C is the cause of a sore throat, even if you test positive for it.
Symptoms depend on where you’re infected. Group C strep symptoms could include:
Streptococcus dysgalactiae subspecies equisimilis (SDSE) is the most common type of group C strep that causes infections. It can naturally live on your skin or in your throat without making you sick. But sometimes, it causes an infection.
You can get it from other people and animals that carry it on their skin or in their throats. Specific ways it can spread include:
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You’re more likely to get a serious strep C infection if you have a long-term medical condition. These include cancer, heart disease, diabetes and conditions that weaken your immune system.
Strep C can travel from where it infects you through your bloodstream. This can lead to:
Some of these conditions can be fatal.
How a healthcare provider diagnoses strep C depends on the symptoms you have. For example, you might need a throat swab, skin biopsy or blood tests. In some cases, you might need additional testing or imaging.
Antibiotics treat group C strep infections. Some infections can be resistant to certain antibiotics. That means that commonly used medications won’t treat the infection. Your provider may need to try different types of antibiotics or a combination to get rid of the infection.
See a healthcare provider if you have symptoms of a group C strep infection. Go to an emergency room if you have:
Strep C infections can be mild or severe. The outcome depends on:
Ask your provider what to expect in your specific situation.
You can reduce your risk of group C strep infections by:
Group A and group C strep are both types of Streptococcus bacteria. Both can cause many kinds of infections. Group A strep is a cause of common infections like strep throat and impetigo. Group C strep infections are uncommon.
Group C strep infections aren’t as common as other types of illnesses. But sometimes, they can be serious. Washing your hands and taking care of wounds can help prevent infections. If you’re at higher risk, talk to your provider about additional steps you can take to protect your health.
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Last reviewed on 08/12/2025.
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