Chondrosarcomas are a group of rare bone cancer tumors that begin in your cartilage. Symptoms include bone pain, a lump or swelling in an area of your body and fatigue. The most common treatment is surgery to remove the tumors, followed by reconstructive surgery. Overall, 79% of people with chondrosarcoma are alive five years after diagnosis.
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A chondrosarcoma is a type of rare bone cancer that typically develops in cartilage — the connective tissue that protects your joints and bones. Healthcare providers may call this condition a sarcoma. Chondrosarcomas are very rare, affecting 1 in 200,000 people in the U.S.
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This cancer can appear anywhere you have cartilage, but it usually forms in your:
They may also develop in benign bone tumors that become cancerous.
There are different types of chondrosarcomas:
Most chondrosarcomas grow slowly, causing symptoms that take months to develop. The most common symptoms are:
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These symptoms don’t always mean bone cancer. But if you have a lump that doesn’t go away within two weeks or you feel exhausted all the time, talk to a healthcare provider. They’ll find out what’s causing your symptoms.
Researchers don’t know the exact cause. But they link the condition to genetic disorders, including:
Medical experts think that in some cases, a change in a chromosome or gene that’s unrelated to an inherited disorder may change cartilage cells.
You can develop a chondrosarcoma at any age, but the condition is more common in people ages 40 to 75. Most people receive a diagnosis at age 51.
Rarer forms, like mesenchymal chondrosarcoma, often affect adults ages 19 to 30.
A healthcare provider will ask about your symptoms and do a physical exam. They may order:
If cells are cancerous, the pathologist will identify the tumor type and establish a tumor grade.
A tumor grade is a measure of how fast a tumor may grow and spread. Chondrosarcoma grades range from 1 (I) to 3 (III):
The most common treatment is surgery to remove cancerous cartilage and bone. The specific surgery depends on factors like the kind of chondrosarcoma, its location and its grade. Surgeries for chondrosarcoma include:
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In all cases, you’ll have physical therapy to help you build strength, balance and mobility as you adapt to your situation.
If you have dedifferentiated or mesenchymal chondrosarcoma, you may have chemotherapy or radiation therapy before surgery to shrink the tumor. You may also need these treatments after surgery to kill any remaining cancer cells.
Living with chondrosarcoma usually starts with recovery. Treatment often involves removing part of a limb or the limb that contains the tumor. Once you’ve recovered, you’ll start a rehabilitation program to help you adjust to using a prosthetic limb.
You might need help adjusting to other changes in how you go about your everyday life. Or you may need help getting used to changes in your appearance. Your healthcare provider will suggest physical, occupational or mental health therapies that may help you manage these challenges.
Ask your provider to explain the kinds of changes in your body that may be signs that cancer has come back, and when it makes sense for you to contact them.
There are several types of chondrosarcomas, each with different prognoses or expected outcomes. In some cases, surgery to remove very small, slow-growing conventional chondrosarcoma tumors may cure the condition. Based on the type of chondrosarcoma, adding chemotherapy may help cure it.
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But fast-growing chondrosarcomas like mesenchymal chondrosarcoma or dedifferentiated chondrosarcoma can be life-threatening.
Ask your healthcare provider what you can expect given your specific situation. They’ll explain your prognosis.
Survival rates for chondrosarcoma vary depending on the tumor type and whether the tumor is spreading. Data collected between 2012 and 2018 show that 78% of people with chondrosarcoma were alive five years after diagnosis. Here are specific survival rates based on tumor location:
Location | Five-year survival rate |
---|---|
Local: There’s no sign of spreading from the bone where it started. | 91% |
Regional: The tumor is spreading from your bone into nearby bones, tissues, organs or lymph nodes. | 71% |
Distant: The tumor is in your lungs or in bones in other parts of your body. | 28% |
Location | |
Local: There’s no sign of spreading from the bone where it started. | |
Five-year survival rate | |
91% | |
Regional: The tumor is spreading from your bone into nearby bones, tissues, organs or lymph nodes. | |
Five-year survival rate | |
71% | |
Distant: The tumor is in your lungs or in bones in other parts of your body. | |
Five-year survival rate | |
28% |
As you think about your situation, try to keep a few things in mind about survival rates:
If you have questions about what a survival rate means in your case, ask your provider to explain how it factors into your situation.
Osteosarcoma starts in the bone and typically affects children. Chondrosarcoma starts in your cartilage and typically affects adults. Healthcare providers may treat chondrosarcoma with surgery alone and treat osteosarcoma with chemotherapy and surgery.
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Being diagnosed with chondrosarcoma is the first step on what could be a long road to recovery. Often, that road starts with surgery to remove your cancer. It continues with rehabilitation to recover from your surgery and other treatments.
While this cancer can be treated successfully, it will change your life. You might need help coping with physical and emotional challenges. Talk to your healthcare provider about the challenges you’re facing. Your provider and care team know what you’re going through. They’ll be with you every step on your journey.
Sarcomas are a rare form of cancer affecting your bones and soft tissues. Our specialists use the latest treatments to care for these types of tumors.
Last reviewed on 07/18/2025.
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