Cholera

Overview

What is cholera?

Cholera is a sudden illness that happens when a person accidentally ingests (swallows) Vibrio cholera (V. cholera) bacteria. When the bacteria infect a person’s intestines, they can cause very bad diarrhea and dehydration. These complications can sometimes lead to death.

How common is cholera?

Millions of people across the world get cholera infections each year. The bacterial infection usually happens in places without modern systems for sewage and clean water. Examples include undeveloped countries and refugee camps, as well as parts of the Middle East, Asia, South America and Africa.

Cholera outbreaks are more common in warm climates. Outbreaks sometimes happen after natural disasters, like earthquakes and hurricanes. These disasters can damage sewage systems.

Cholera is rare in the United States and other modern, industrialized countries. But Americans should be aware of the disease and its causes, especially if they travel internationally.

Symptoms and Causes

What causes cholera?

Cholera comes from the V. cholera bacteria. People infected with these bacteria can spread disease through their feces (also called stool or poop). They do so when infected feces get into the water system. If the water isn’t properly sanitized (cleaned), people using the water to drink, cook and wash risk exposure.

When a person eats or drinks food or water that contains V. cholera, the bacteria grow inside them. The bacteria then make the small intestines secrete (leak) fluid, leading to diarrhea.

Cholera usually doesn’t spread directly from person to person, but it can. So it’s important to wash your hands to prevent infection.

Cholera bacteria also live in salty rivers and coastal waters. Some people have gotten cholera from eating raw or undercooked shellfish, though that’s rare.

What are the symptoms of cholera?

A cholera infection can be mild, with no symptoms. But about 10% of infected people develop severe symptoms, 12 hours to five days after ingesting the bacteria. These symptoms include:

  • Diarrhea, or extremely watery poop.
  • Intense thirst.
  • Lower amounts of urine (pee).
  • Muscle cramps.
  • Restlessness or irritability.
  • Vomiting.
  • Weakness.

If you develop any cholera symptoms, immediately contact a healthcare provider. Mild symptoms may go away on their own in a few days. But dehydration can become deadly very quickly. Early treatment can save your life.

What problems can cholera cause?

Diarrhea and vomiting from cholera can make your body lose large amounts of important substances:

When your body doesn’t have enough of those things, you get dehydrated and may develop:

  • Dry mucous membranes (such as in the eyes, nose and mouth).
  • Fast heart rate.
  • Hypokalemia (low potassium levels in the blood).
  • Hypotension (low blood pressure).
  • Loss of the natural stretchiness in skin.

Untreated, severe dehydration from cholera can lead to:

Diagnosis and Tests

How is cholera diagnosed?

To test for cholera, a healthcare provider will need a sample of your stool. Often, you will poop into a collection cup or bag. Sometimes, a healthcare provider will insert a swab into your rectum (opening where poop comes out).

The sample gets sent to a laboratory, where experts will look at it under a microscope to identify the bacterium V. cholera. Some areas where cholera is more common have access to a “dipstick” tool that can rapidly test a stool sample.

Management and Treatment

How is cholera treated?

The most important part of cholera treatment is preventing or reversing dehydration. Anyone with cholera should immediately replace the fluids and salts they’ve lost. A healthcare provider may prescribe:

  • Oral rehydration solution (ORS): You may have to drink large amounts of a prepackaged mix of sugar, salts and water.
  • Intravenous fluids: For a severe case of dehydration, a healthcare provider may use a needle to pump fluids directly into your veins.

Other treatments may include:

V. cholera bacteria usually disappear from the body within two weeks.

Prevention

How can I avoid cholera?

People who don’t live in or visit areas with poor sanitation have little chance of getting cholera. But if you’re in an area with cholera cases, certain strategies can help prevent infections:

  • Avoid tap water, water fountains and ice cubes. This precaution applies to water you drink and water you use to wash dishes, prepare food and brush your teeth.
  • Don’t eat raw or undercooked seafood.
  • Drink water only if it’s bottled, canned, boiled or treated with certain chemicals. And don’t drink out of a bottle or can with a broken seal.
  • Eat prepackaged foods. Or make sure other foods are freshly cooked and served hot.
  • Consider disinfecting your water: Boil it for at least one minute. Add half an iodine tablet or two drops of household bleach to each liter of water. Or use chlorine tablets.
  • Wash fruits and vegetables with clean water.
  • Wash your hands with soap and clean water, especially before handling and eating food and after using the bathroom. If clean water and soap aren’t available, use hand sanitizer made of at least 60% alcohol.

Is there a vaccine for cholera?

The U.S. Food and Drug Administration (FDA) has approved one vaccine for cholera (Vaxchora®). It’s for adults ages 18 to 64 who plan to travel to areas with cholera. But the vaccine isn’t recommended very often because most tourists don’t visit places with cholera. Two other cholera vaccines exist but aren’t approved in the United States.

Vaccines aren’t 100% effective, so you should still take care when traveling. Follow precautions with food and water, and wash your hands often.

Outlook / Prognosis

What is the outlook for someone with cholera?

Cholera may go away on its own in just a few days. But if you have severe symptoms and start to become dehydrated, you need medical attention. You must replace fluids very quickly.

Living With

How can I protect myself if I plan to be in an area with cholera?

The Centers for Disease Control and Prevention (CDC) has a website where travelers can check for outbreaks of cholera and other diseases (Visit their Travel Health Notices website.)

If you live in an area with cholera or plan to travel to one, make sure you’re careful about the water you drink. Wash your hands and prepare food carefully. The following supplies might help:

  • Bottled water.
  • Chlorine tables.
  • Household bleach.
  • Iodine tablets.
  • Prepackaged foods.

A note from Cleveland Clinic

If you have severe diarrhea from cholera or another cause, contact a healthcare provider immediately. You must replace fluids and electrolytes to avoid dehydration. This complication can cause serious health problems and even death.

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy