Head and Neck Surgery and Oncology

Does Neck Dissection Affect Post-Operative Outcomes in Parotidectomy? A National Study

2005-2017

The objective of this study was to characterize post-operative complications in parotidectomy with neck dissection. Patients age ≥ 18 receiving a parotidectomy or parotidectomy with neck dissection between 2005 and 2017 were eligible for inclusion. Patients with unknown demographic variables were excluded. Univariate and multivariable logistic regression analyses were performed.

Post-Operative Outcomes Analysis Comparing Parotidectomy With and Without Neck Dissection (N = 13,609)

2005-2017

OutcomeParotid (N = 11,243)Parotid With Neck Dissection (N = 2366)𝙋-Value
Total operation time (Mean ± SD)152.9 ± 99.0335.9 ± 189.2<0.0001
Days from operation to discharge (Mean ± SD)1.04 ± 2.143.90 ± 4.76<0.0001
30-day return to OR186 (1.7%)133 (5.6%)<0.0001
Any readmission181 (1.9%)113 (5.4%)<0.0001
Death within 30 days12 (0.1%)16 (0.7%)<0.0001
Any complication399 (3.5%)330 (13.9%)<0.0001
Surgical complications305 (2.7%)260 (11.0%)<0.0001
Superficial SSI176 (1.6%)63 (2.7%)0.0002
Deep Incisional SSI43 (0.4%)27 (1.1%)<0.0001
Organ Space SSI21 (0.2%)5 (0.2%)0.7954`
Wound dehiscence/Disruption30 (0.3%)28 (1.2%)<0.0001
Transfusion Intra/Post Op (e.g. due to severe bleeding)53 (0.5%)175 (7.4%)<0.0001
Medical complication117 (1.0%)111 (4.7%)<0.0001
Pneumonia24 (0.2%)31 (1.3%)<0.0001
Unplanned intubations14 (0.1%)22 (0.9%)<0.0001
Urinary tract infection34 (0.3%)15 (0.6%)0.0144
DVT/Thrombophlebitis16 (0.1%)6 (0.3%)0.2207
Pulmonary embolism5 (0.0%)9 (0.4%)0.0001
On ventilator > 48 hours13 (0.1%)19 (0.8%)<0.0001
CVA/Stroke with Neurological deficit11 (0.1%)10 (0.4%)0.0003
Cardiac arrest requiring CPR6 (0.1%)8 (0.3%)<0.0001
Myocardial infarction10 (0.1%)15 (0.6%)<0.0001
Sepsis19 (0.2%)16 (0.7%)<0.0001
Septic shock4 (0.0%)4 (0.2%)0.0353
Progressive renal failure7 (0.1%)1 (0.0%)1.000
Acute renal failure3 (0.0%)3 (0.1%)0.580

Nationwide data demonstrates that parotidectomy with neck dissection is associated with increased rates of post-operative complications; however, neck dissection did not significantly impact readmission or reoperation rates. These findings indicate that neck dissection is a relatively safe addition to parotidectomy and provide novel evidence in the management of parotid malignancies.

References

Brauer PR, Reddy CA, Ku JA, et al. Does neck dissection affect post-operative outcomes in parotidectomy? A national study. Am J Otolaryngol. 2020 Sep-Oct;41(5):102593.