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Radiation Therapy

Novalis Tx Radiosurgery

Cleveland Clinic's Radiation Oncology Specialists care for more patients than any other cancer center in Ohio. Our multidisciplinary approach to cancer care coupled with the use of cutting edge technologies, dedication to research and education, and strong focus on patient care provide better outcomes and experiences for our patients.

General Information

What is Radiation Therapy?

Find answers to many of your questions about Radiation Therapy, as well as what to expect during the process.

Types of Cancer Treated

Learn about the types of cancer we treat at the Cleveland Clinic, including brachytherapy and radiotherapy.

Types of Treatment

Get more information about the types of treatment available through Cleveland Clinic’s radiation therapy services.

Types of Treatment

Active Breathing Coordinator

Active Breathing Coordinator is a device that allows greater conformity of the radiation beam to the tumor.


Brachytherapy is a type of radiation therapy involving the placement of radiation sources near the tumor or within a body cavity.

Calypso 4D - Prostate Cancer Treatment

The Calypso™ 4D Localization System for treating prostate cancer is a unique radiation targeting technology that works like a GPS system.

Clarity Breast System

Clarity Breast System gives more accurate targeting of the treatment area without added risk.

Hyperthermia Therapy

Hyperthermia increases tumor temperature to stimulate blood flow, increasing oxygenation and renders tumor cells more sensitive to radiation.

Image Guided Radiation Therapy

Image guided radiation therapy (IGRT) involves the use of imaging technology such as X-ray, ultrasound, or optical imaging to direct the delivery of radiation.

Intensity Modulated Radiation Therapy

Intensity Modulated Radiation Therapy (IMRT) is the practice of delivering multiple beams of radiation to separate tumor sites in order to more effectively treat large tumor areas.

Intraoperative Radiation Therapy

The Intrabeam Intraoperative Radiation Therapy (IORT) device delivers low energy, high dose radiation directly to the tumor bed in the operating room.

Novalis Tx Radiosurgery

Novalis Tx radiosurgery accurately shapes the radiation beam to the area to be treated and uses imaging guidance and other methods to target the tissue or tumor.

Prone Breast Therapy

Prone Breast treatment substantially limits the radiation dose that reaches the heart, lung, and skin.

Radioactive Plaque Therapy

The plaque is positioned on the surface of the eyeball directly over the tumor inside the eye delivering a high dose of radiation.

Radiolabeled Antibody Therapy

Radiolabeled Antibody Therapy is injected into the circulation and allowed to localize simultaneously in many different sites of disease involvement.

Rapid Arc Radiation Therapy

Highly-concentrated doses of radiation delivered directly to tumors, without damaging healthy cells - in two minutes.


TheraSphere consists of millions of radioactive microscopic glass spheres, which are infused into the arteries that feed liver tumors.

Total Body Irradiation

Total Body Irradiation is often given in the context of a bone marrow transplant, and in the past it has generally involved very high doses of radiation given over a period of days.

Edge by Varian

The Edge is a state-of-the-art linear accelerator coupled with real-time motion management to ensure fast, precise delivery of treatment.

Cancer Answers & Appointments

Speak with a cancer nurse specialist for appointment assistance and for answers to your questions about cancer locally at 216.444.7923 or toll-free 1.866.223.8100.

Monday through Friday from 8 a.m. – 4:30 p.m. (ET).


Resources for medical professionals

  • Outpatient appointment referrals: 216.444.7923 or 866.223.8100
  • Inpatient hospital transfers: 800.553.5056
  • Referring Physician Concierge: 216.444.6196 or 216.312.4910.

Clinical Trials

Search available cancer clinical trials by disease, hospital, phase or number.