Azathioprine, a medication in tablet form, treats immune diseases, most notably multiple sclerosis (MS). Find out about the side effects and when you should contact your healthcare provider.
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Azathioprine (Imuran®) is a medication that treats diseases that have to do with your immune system. It’s been used in some patients with multiple sclerosis (MS), usually if they have problems with standard FDA-approved medications for their MS.
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Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy
Studies have shown that azathioprine can reduce the number of flare-ups in patients with relapsing MS. It also can reduce new MRI lesion formation. Azathioprine might also be used with other medications to boost their effects. It is not FDA approved specifically for MS.
Azathioprine comes in tablet-form, and it’s swallowed (oral).
Your white blood cell count and your weight determine the dosage of azathioprine that is prescribed. The starting dose is low and is slowly increased. Azathioprine is generally taken twice a day. It is available in 50 mg tablets, which may be easily broken in half if necessary. You may take this medication with food to reduce nausea and abdominal symptoms.
Your prescription label tells you how much to take of each dose and how often to take it. Follow these instructions carefully, and ask your pharmacist or healthcare provider to explain anything you don’t understand.
It is important that you take this medicine regularly as prescribed. Do not stop taking it unless you are directed to do so. Do not take more or less of the medicine than is prescribed.
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Most people handle this medicine very well. It is important to remember that not everyone experiences all of these side effects. Even though some of the side effects could be serious, remember that precautions will be taken to detect and treat them before they become harmful. You should call your healthcare provider if any of the following reactions occur:
If you forget to take a dose, take it as soon as you remember and then continue to follow your regular schedule.
Call your healthcare provider right away if you have any of these warning signs of infection:
Call your healthcare provider if you have any other symptoms that cause concern.
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Last reviewed on 01/06/2021.
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