What are leukotriene modifiers, and what do they do?
Some examples of leukotriene modifiers are montelukast sodium (Singulair®), zafirlukast (Accolate®), and zileuton (Zyflo®). These medications block chemicals that cause the airways to narrow and tighten.
How are these medications supplied?
Leukotriene modifiers are available in tablet form.
What are possible side effects?
- Indigestion and/or nausea
- Diarrhea
- Headache
- Fatigue
You should notify your doctor if you:
- Take theophylline, Coumadin®, Inderal®, or aspirin
- Take Zyflo and develop abdominal pain on the right side, or if you have yellow skin
Note: The side effects listed are the most common. Always contact your health care provider if you have questions about your personal situation.
How and when should do you take leukotriene modifiers? Are there special instructions?
- Do not use for "quick relief" of sudden symptoms.
- Swallow tablets whole; do not chew or crush tablets.
- Continue to take the medication as prescribed, even if your symptoms are under control and you feel better.
- Take Singulair regularly once a day in the evening.
- Take Accolate one hour before or two hours after a meal.
- Blood tests may be performed periodically.
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This information is provided by the Cleveland Clinic and is not intended to replace the medical advice of your doctor or health care provider. Please consult your health care provider for advice about a specific medical condition. This document was last reviewed on: 8/15/2008…#14278