Zileuton is a medication that treats asthma. This condition causes your airways to narrow and swell and block with excess mucus. Zileuton comes in a tablet form that you can take by mouth with a glass of water as directed. Take each dose at regular intervals.
ZILEUTON (zye LOO ton) prevents and treats the symptoms of asthma. It works by decreasing inflammation of the airways, making it easier to breathe. Do not use it to treat a sudden asthma attack.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
COMMON BRAND NAME(S): Zyflo
They need to know if you have any of these conditions:
Take this medication by mouth. Take it as directed on the prescription label at the same time every day. You can take it with or without food. If it upsets your stomach, take it with food. You may cut the tablet in half if it is scored (has a line in the middle of it). This may help you swallow the tablet if the whole tablet is too big. Be sure to take both halves. Do not take just one-half of the tablet. Keep taking it unless your care team tells you to stop.
Talk to your care team about the use of this medication in children. While it may be prescribed for children as young as 12 years for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
This medication may interact with the following:
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
Visit your care team for regular checks on your progress. Tell your care team if your symptoms do not start to get better or if they get worse. Take your medication even when you do not have symptoms. Do not stop taking any of your medication(s) unless your care team tells you to.
If you have asthma, talk to your care team about what to do in an acute asthma attack. Always have your inhaled rescue medication for asthma attacks with you.
You may need blood work done while taking this medication.
Patients and their families should watch for new or worsening thoughts of suicide or depression. Also watch for sudden changes in feelings such as feeling anxious, agitated, panicky, irritable, hostile, aggressive, impulsive, severely restless, overly excited and hyperactive, or not being able to sleep. Any worsening of mood or thoughts of suicide or dying should be reported to your care team right away.
Side effects that you should report to your care team as soon as possible:
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Keep out of the reach of children and pets.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from light. Keep the container tightly closed. Get rid of any unused medication after the expiration date.
To get rid of medications that are no longer needed or have expired:
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
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Note: Introduction and Additional Common Questions written and medically approved by Cleveland Clinic professionals.