Department Endocrinology, Diabetes and Metabolism
Primary Location Twinsburg Family Health & Surgery Center
Type of Doctor Adults Only
Languages English
Surgeon No
Twinsburg Family Health & Surgery Center
Primary Location

Twinsburg Family Health & Surgery Center


Additional Locations

Specialties & Treatments

Treatment & Services

  • Radioactive Iodine Treatment
  • Thyroid Aspiration
  • Thyroid Ultrasound
  • Thyroid Ultrasound And Biopsy
View all 4 Treatment & Services +

Specialty in Diseases & Conditions

  • Acromegaly
  • Addison's Disease
  • Adrenal disorders
  • Adrenal insufficiency
  • Adrenal Tumors
  • Adrenocortical Carcinoma
  • Adrenoleukodystrophy (ALD)
  • Amenorrhea
  • Androgen Excess
  • Bone Disorders
  • Calcium Disorders
  • Carcinoid Syndrome
  • Conn's Syndrome
  • Cushing's Syndrome
  • Diabetes
  • Diabetes, Gestational
  • Empty sella
  • Endocrine Complications of Pregnancy
  • Endocrine Disorders
  • Endocrine Hypertension
  • Familial Multiple Endocrine Neoplasia
  • Fasting hypoglycemia
  • Flushing Syndromes
  • Galactorrhea
  • Goiter
  • Growth hormone deficiency
  • Growth hormone excess
  • Gynecomastia
  • High Cholesterol
  • Hirsutism
  • Hyperaldosteronism
  • Hyperandrogenism
  • Hypercalcemia
  • Hyperparathyroidism
  • Hyperprolactinemia
  • Hypertension - High Blood Pressure
  • Hyperthyroidism
  • Hypertriglyceridemia
  • Hypocalcemia
  • Hypogonadism
  • Hypoparathyroidism
  • Hypophysitis
  • Hypopituitarism
  • Hypothyroidism
  • Klinefelter Syndrome
  • Mastocytosis
  • McCune-Albright Syndrome
  • Menopause, Male
  • Metabolic Bone Disease
  • Metabolic Diseases
  • Metabolic Syndrome
  • Obesity
  • Osteopenia
  • Osteoporosis
  • Pancreatic Endocrine Tumors
  • Pancreatitis
  • Panhypopituitarism
  • Parathyroid Cancer
  • Parathyroid Disease Description
  • Pheochromocytoma
  • Pituitary Cysts
  • Pituitary Disorders
  • Pituitary stalk lesions
  • Pituitary Tumors
  • Polycystic Ovary Syndrome
  • Primary Hyperaldosteronism
  • Prolactin Excess States
  • Prolactinoma
  • Pseudohypoparathyroidism
  • Reactive hypoglycemia
  • Secondary Hyperparathyroidism
  • Thyroid and pregnancy
  • Thyroid Cancer
  • Thyroid Disease
  • Thyroid Nodule
  • Vitamin D Deficiency
  • Zollinger-Ellison Syndrome
View all 77 Specialties +


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About Kevin M. Pantalone, DO

Dr. Pantalone is a board certified Staff Endocrinologist at Cleveland Clinic in Cleveland, Ohio. He currently serves as the Director of Clinical Research in the Department of Endocrinology. Dr. Pantalone is a graduate of Ohio University College of Osteopathic Medicine.  He completed his internal medicine residency and endocrinology fellowship at Cleveland Clinic.  He was designated a Fellow of the American College of Endocrinology (FACE) in 2015.  His clinical focus is on the glycemic management of type 2 diabetes, as well as the diagnosis and management of low testosterone in men, thyroid disorders, and pituitary tumors.  His research interests are related to the adverse effects of diabetes therapies, particularly those related to sulfonylureas.  He is also actively involved in health outcomes research using the enterprise-wide electronic health record system at Cleveland Clinic.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Cleveland Clinic
Cleveland, OH USA

Internship - Cleveland Clinic
Cleveland, OH USA

Residency - Cleveland Clinic
Internal Medicine
Cleveland, OH USA

Medical School - Ohio University College of Osteopathic Medicine
Athens, OH USA

Undergraduate - Kent State University
Kent, OH USA

Additional Training

  • Endocrine Certification in Neck Ultrasound (ECNU)

Professional Highlights

  • Dr. Pantalone received local and national media attention for research pertaining to adverse outcomes with sulfonylurea therapy.


  • Internal Medicine
  • Internal Medicine - Endocrinology, Diabetes and Metabolism

Awards & Honors

  • Appointed to the American College of Endocrinology to serve as a member of the ACE Scientific Referencing Team (ASRT), 2016
  • Manuscript reviewer for The Lancet, 2016 to present
  • NIH-R01 co-investigator Dynamics of Muscle Mitochondria in Type 2 Diabetes (DYNAMMO T2D).  Roles include advising with subject recruitment and advising with the Standard of Care component of the intervention for the type 2 diabetes group and helping with the screening process (2015-2020).
  • Chosen by the Endocrine Society to participate in the society’s annual media training seminar (2015) to assist the society with endocrine-related media requests
  • Nominated by department leadership to complete the annual “Leading in Health Care” course at Cleveland Clinic, 2015-2016.
  • Fellow of the American College of Endocrinologists (FACE), 2015
  • Guest Editor, J Am Osteopath Assoc. 2015 Apr 1;115(4_suppl):eS3-eS4.
  • Abstract Reviewer, Clinical Diabetes, The Endocrine Society, 2014 
  • Appointed Director of Clinical Research for the Department of Endocrinology, Diabetes & Metabolism at Cleveland Clinic, August of 2014
  • Principal Investigator and Regional Study Leader for DEVOTE: A Trial Comparing Cardiovascular Safety of Insulin Degludec Versus Insulin Glargine in Subjects With Type 2 Diabetes at High Risk of Cardiovascular Events
  • Manuscript reviewer for The New England Journal of Medicine, 2014 to present
  • Manuscript reviewer for The Lancet Diabetes and Endocrinology, 2014 to present
  • Authored an online fellow’s module addressing the diagnosis and treatment of male hypogonadism for the American Association of Clinical Endocrinologists, May 2013
  • Received national media attention for research pertaining to adverse outcomes with sulfonylurea therapy (The Endocrine Society, U.S. News and World Report, Medscape Medical News, etc.)
  • Received local media attention for research pertaining to adverse outcomes with sulfonylurea therapy; featured in Akron Beacon JournalJuly 10, 2012
  • Interviewed by Diabetes Radio/Optimal Clinical regarding my research entitled a href="">The risk of overall mortality in patients with Type 2 diabetes receiving different combinations of sulfonylureas and metformin: a retrospective analysis, March 2012.
  • Cleveland Clinic Endocrinology and Metabolism Institute Research Award Winner, Best Research Presentation, April 2011
  • Chief Fellow, Department of Endocrinology, Diabetes, and Metabolism, Cleveland Clinic, 2010-2011
  • Presidential Poster Competition Winner, The Endocrine Society National Meeting, San Diego, CA, June 2010
  • Cleveland Clinic Endocrinology and Metabolism Institute Research Award Winner, Best Research Presentation, April 2010 
  • Fellow representative for the Cleveland Clinic Diabetes Care Team, a multidisciplinary team of health care providers which meets on a monthly basis to address issues pertaining to diabetes management in the hospital setting, July 2009 to June 2011
  • Cleveland Clinic Internal Medicine Senior Resident of the Year, 2008-2009
  • Cleveland Clinic Peskind Award, Best Clinical or Nonclinical Paper from a Resident in the Division of Medicine, June 2009
  • Cleveland Clinic Resident Research Competition Winner and Internal Medicine Grand Rounds Presentation, Best Internal Medicine Resident Research Project, June 2009
  • Graduated in the top 10% at Ohio University College of Osteopathic Medicine, June 2006
  • Valedictorian of College of Arts and Sciences, Kent State University, May 2002, GPA 4.0
  • Recognized as one of the brightest college students in Northeast Ohio in Northeastern Ohio Live MagazineMay 2002
  • Mary Manchester Award for Superior Scholarship, Leadership and Constructive Citizenship, April 2002
  • Superior Research Award, Lubrizol Corporation and Kent State University, April 2002
  • Phi Beta Kappa National Honors Society, inducted April 2002
  • Golden Key National Honors Society, inducted March 2001


  • The Endocrine Society
  • American Association of Clinical Endocrinologists
  • The Pituitary Society and American Diabetes Association
Research & Publications

Research & Publications

See publications for Kevin M. Pantalone, DO.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 10/3/2018, Dr. Pantalone has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Consulting and/or Speaking. Dr. Pantalone receives fees of $5,000 or more per year as a paid consultant, speaker or member of an advisory committee for the following companies:

  • Merck & Co., Inc.
  • Sanofi S.A.
  • Novo Nordisk, A/S
  • AstraZeneca

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

126 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
5 out of 5
Explains 5
Listens 5
Courtesy, Respect & Concern 5
Knows Medical History 5
Time Spent with Patient 5
Patient Rating of Doctor 5

16 Patient Comments

Reviewed on Nov 12, 2018

Dr. Pantalone is probably the BEST Physician I have ever had. He is personable and caring. HE is what all Doctors should aspire to!

Reviewed on Nov 5, 2018

It is actually a treat to go to see Dr. Pantalone.

Reviewed on Oct 22, 2018

I think Dr. Pantalone is a really good doctor. In fact, I have referred one of my friends to him.

Reviewed on Aug 31, 2018

Dr. Pantalone is very patient he communicates very well in the manner to understand the dx: Always experience a good interactions.

Reviewed on Aug 27, 2018

Dr. Pantalone and his staff are always helpful and courteous they really take their time and make you feel at ease

Reviewed on Aug 27, 2018

Dr Pantalone is a very thorough and caring physician. Whenever I leave his office, I feel he has given me the best possible care.

Reviewed on Aug 20, 2018

Dr. Pantalone has been treating me for a number of years. He is always polite, knowledgeable and respectful.

Reviewed on Jun 18, 2018

I have never had a problem with any Doctor and/or Cleveland Clinic. I may have had to wait a few minutes extra to see my Doctor on 6/18/18 because Dr. Pantelone's schedule of patients was backed, but THIS DOCTOR IS WORTH THE WAIT. He is very courteous, knowledgeable, and caring about his patients, what they think and feel and what their needs are. Dr. Pantelone is a SUPERB Doctor that I feel privileged to have.

Reviewed on May 30, 2018

Have always had a good experience atCC. Dr. Pantalone is wonderful.

Reviewed on May 30, 2018

I don't mind driving the 30 minutes. Dr. Pantalone is a great doctor and I feel he has my best (medical) interests at heart.

Reviewed on Apr 30, 2018

Dr. Kevin M Pantalone is excellent. He takes the time to listen and provides options and solutions. I appreciate the time he takes during my scheduled appointments.

Reviewed on Apr 16, 2018

*Dr. Pantalone is very knowledgeable and personable. I trust him completely.

Reviewed on Apr 16, 2018

Outstanding Experience, Outstanding Dr.(Dr.Pantalone)

Reviewed on Apr 11, 2018

Dr.Pantalone is one of the most professional and caring doctors at the Clinic. He is the reason I continue to come there. You need many more doctors like him. I always have a good appointment with him. I TRUST whatever he tells me to do that it is for my well being. I never have to second guess him. He is atrue asset to the Ckinic,

Reviewed on Mar 12, 2018

I have seen this doctor several times, and all of the visits were positive. The distance, 50 miles, causes some problems. I had to hire a driver.

Reviewed on Jan 29, 2018

Dr Pantalone takes the time to explain all of my medications. He is so wonderful.

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