alert icon Coronavirus
Now scheduling COVID-19 vaccines for ages 12+, boosters and third doses
Schedule your appointment
COVID-19 vaccine FAQs

Going to a Cleveland Clinic location?
New visitation guidelines
Masks required for patients and visitors (even if you're vaccinated)

Department Endocrinology, Diabetes and Metabolism
Primary Location Twinsburg Family Health & Surgery Center
Type of Doctor Adults Only
Languages English
Surgeon No
Twinsburg Family Health & Surgery Center
Primary Location

Twinsburg Family Health & Surgery Center

Specialties & Treatments

Treatment & Services

  • Radioactive Iodine Treatment
  • Thyroid Aspiration
  • Thyroid Ultrasound
  • Thyroid Ultrasound And Biopsy
View all 4 Treatment & Services +

Specialty in Diseases & Conditions

  • Acromegaly
  • Addison's Disease
  • Adrenal disorders
  • Adrenal insufficiency
  • Adrenal Tumors
  • Adrenocortical Carcinoma
  • Adrenoleukodystrophy (ALD)
  • Amenorrhea
  • Androgen Excess
  • Bone Disorders
  • Calcium Disorders
  • Carcinoid Syndrome
  • Conn's Syndrome
  • Cushing's Syndrome
  • Diabetes
  • Diabetes, Gestational
  • Empty sella
  • Endocrine Complications of Pregnancy
  • Endocrine Disorders
  • Endocrine Hypertension
  • Familial Multiple Endocrine Neoplasia
  • Fasting hypoglycemia
  • Flushing Syndromes
  • Galactorrhea
  • Goiter
  • Growth hormone deficiency
  • Growth hormone excess
  • Gynecomastia
  • High Cholesterol
  • Hirsutism
  • Hyperaldosteronism
  • Hyperandrogenism
  • Hypercalcemia
  • Hyperparathyroidism
  • Hyperprolactinemia
  • Hypertension - High Blood Pressure
  • Hyperthyroidism
  • Hypertriglyceridemia
  • Hypocalcemia
  • Hypogonadism
  • Hypoparathyroidism
  • Hypophysitis
  • Hypopituitarism
  • Hypothyroidism
  • Klinefelter Syndrome
  • Mastocytosis
  • McCune-Albright Syndrome
  • Menopause, Male
  • Metabolic Bone Disease
  • Metabolic Diseases
  • Metabolic Syndrome
  • Obesity
  • Osteopenia
  • Osteoporosis
  • Pancreatic Endocrine Tumors
  • Pancreatitis
  • Panhypopituitarism
  • Parathyroid Cancer
  • Parathyroid Disease Description
  • Pheochromocytoma
  • Pituitary Cysts
  • Pituitary Disorders
  • Pituitary stalk lesions
  • Pituitary Tumors
  • Polycystic Ovary Syndrome
  • Primary Hyperaldosteronism
  • Prolactin Excess States
  • Prolactinoma
  • Pseudohypoparathyroidism
  • Reactive hypoglycemia
  • Secondary Hyperparathyroidism
  • Thyroid and pregnancy
  • Thyroid Cancer
  • Thyroid Disease
  • Thyroid Nodule
  • Vitamin D Deficiency
  • Zollinger-Ellison Syndrome
View all 77 Specialties +


Is Cleveland Clinic Part of Your Insurance?

Review a list of accepted insurance plans for our Northeast Ohio locations or learn more about purchasing a contracted managed care plan.

View All Plans

About Kevin M. Pantalone, DO

Dr. Pantalone is a board certified Staff Endocrinologist at Cleveland Clinic in Cleveland, Ohio. He currently serves as the Director of Diabetes Initiatives in the Department of Endocrinology. He previously served as the Director of Clinical Research for the Department of Endocrinology from 2014-2019. Dr. Pantalone is a graduate of Ohio University College of Osteopathic Medicine. He completed his internal medicine residency and endocrinology fellowship at Cleveland Clinic.

He was designated a Fellow of the American College of Endocrinology (FACE) in 2015. His clinical focus is on the glycemic management of type 2 diabetes, as well as the diagnosis and management of low testosterone in men, thyroid disorders, and pituitary tumors. His research interests are related to the adverse effects of diabetes therapies, particularly those related to sulfonylureas. He is also actively involved in health outcomes research using the enterprise-wide electronic health record system at Cleveland Clinic.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Cleveland Clinic
Cleveland, OH USA

Internship - Cleveland Clinic
Cleveland, OH USA

Residency - Cleveland Clinic
Internal Medicine
Cleveland, OH USA

Medical Education - Ohio University College of Osteopathic Medicine
Athens, OH USA

Undergraduate - Kent State University
Kent, OH USA

Additional Training

  • Endocrine Certification in Neck Ultrasound (ECNU)

Professional Highlights

  • Dr. Pantalone has received local and national media attention for research pertaining to adverse outcomes with sulfonylurea therapy.   He has served as the Director of Clinical Research for the Department of Endocrinology, Diabetes & Metabolism at Cleveland Clinic since 2014.  His research ris egularly featured in Healio Endocrine today,  His commentary on recently published studies pertaining to diabetes is featured regularly by Endocrinology Advisor,  He is a member of MD Magazine’s Advisory Board, and serves on numerous institutional, ADA, and AACE committees.


  • Internal Medicine - Endocrinology, Diabetes and Metabolism

Awards & Honors

  • Appointed member of the steering committee for NN8022-4432, An Obesity Pragmatic ClinicalTrial, 2018
  • Appointed to the American College of Endocrinology (College) Task Force to serve as amember of the ACE CPG Oversight Committee, 2018
  • Nominated by department leadership to complete the “Introduction to Emotional Intelligence” course at the Case Western Reserve Weatherhead School of Management, July, 2018.
  • Featured regularly by Endocrinology Advisor, providing commentary on recently published studies pertaining to diabetes, 2017 to present.
  • Appointed to Research Executive Committee, Cleveland Clinic, 2017 to present
  • Research Information Technology Advisory Board, Cleveland Clinic, 2017 to present
  • Appointed to Patient Access Steering Committee, Cleveland Clinic, 2017 to present
  • Member of MD Magazine’s Advisory Board, 2017 to present
  • Principal Investigator for PIONEER-6: A Trial Investigating the Cardiovascular Safety of Oral Semaglutide in Subjects with Type 2 Diabetes
  • Appointed to the American College of Endocrinology (College) Task Force to Update the AACE Growth Hormone Clinical PracticeGuidelines, 2017
  • Appointed to the American College of Endocrinology to serve as a member of the ACE Scientific Referencing Team (ASRT), 2016
  • Manuscript reviewer for The Lancet, 2016 to present
  • NIH-R01 co-investigator Dynamics of Muscle Mitochondria in Type 2 Diabetes (DYNAMMO T2D).  Roles include advising with subject recruitment and advising with the Standard of Care component of the intervention for the type 2 diabetes group and helping with the screening process (2015-2020).
  • Chosen by the Endocrine Society to participate in the society’s annual media training seminar (2015) to assist the society with endocrine-related media requests
  • Nominated by department leadership to complete the annual “Leading in Health Care” course at Cleveland Clinic, 2015-2016.
  • Fellow of the American College of Endocrinologists (FACE), 2015
  • Guest Editor, J Am Osteopath Assoc. 2015 Apr 1;115(4_suppl):eS3-eS4.Abstract Reviewer, Clinical Diabetes, The Endocrine Society, 2014 
  • Appointed Director of Clinical Research for the Department of Endocrinology, Diabetes & Metabolism at Cleveland Clinic, August of 2014
  • Principal Investigator and Regional Study Leader for DEVOTE: A Trial Comparing Cardiovascular Safety of Insulin Degludec Versus Insulin Glargine in Subjects With Type 2 Diabetes at High Risk of Cardiovascular Events
  • Manuscript reviewer for The New England Journal of Medicine, 2014 to present
  • Manuscript reviewer for The Lancet Diabetes and Endocrinology, 2014 to present
  • Authored an online fellow’s module addressing the diagnosis and treatment of male hypogonadism for the American Association of Clinical Endocrinologists, May 2013
  • Received national media attention for research pertaining to adverse outcomes with sulfonylurea therapy (The Endocrine Society, U.S. News and World Report, Medscape Medical News, etc.)
  • Received local media attention for research pertaining to adverse outcomes with sulfonylurea therapy; featured in Akron Beacon JournalJuly 10, 2012
  • Interviewed by Diabetes Radio/Optimal Clinical regarding my research entitled a href="">The risk of overall mortality in patients with Type 2 diabetes receiving different combinations of sulfonylureas and metformin: a retrospective analysis, March 2012.
  • Cleveland Clinic Endocrinology and Metabolism Institute Research Award Winner, Best Research Presentation, April 2011
  • Chief Fellow, Department of Endocrinology, Diabetes, and Metabolism, Cleveland Clinic, 2010-2011
  • Presidential Poster Competition Winner, The Endocrine Society National Meeting, San Diego, CA, June 2010
  • Cleveland Clinic Endocrinology and Metabolism Institute Research Award Winner, Best Research Presentation, April 2010 
  • Fellow representative for the Cleveland Clinic Diabetes Care Team, a multidisciplinary team of health care providers which meets on a monthly basis to address issues pertaining to diabetes management in the hospital setting, July 2009 to June 2011
  • Cleveland Clinic Internal Medicine Senior Resident of the Year, 2008-2009
  • Cleveland Clinic Peskind Award, Best Clinical or Nonclinical Paper from a Resident in the Division of Medicine, June 2009
  • Cleveland Clinic Resident Research Competition Winner and Internal Medicine Grand Rounds Presentation, Best Internal Medicine Resident Research Project, June 2009
  • Graduated in the top 10% at Ohio University College of Osteopathic Medicine, June 2006
  • Valedictorian of College of Arts and Sciences, Kent State University, May 2002, GPA 4.0
  • Recognized as one of the brightest college students in Northeast Ohio in Northeastern Ohio Live MagazineMay 2002
  • Mary Manchester Award for Superior Scholarship, Leadership and Constructive Citizenship, April 2002
  • Superior Research Award, Lubrizol Corporation and Kent State University, April 2002
  • Phi Beta Kappa National Honors Society, inducted April 2002
  • Golden Key National Honors Society, inducted March 2001


  • The Endocrine Society
  • American Association of Clinical Endocrinologists
  • The American Diabetes Association
Research & Publications

Research & Publications

See publications for Kevin M. Pantalone, DO.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 9/21/2021, Dr. Pantalone has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Consulting and/or Speaking. Dr. Pantalone receives fees of $5,000 or more per year as a paid consultant, speaker or member of an advisory committee for the following companies:

  • Bayer Healthcare Pharmaceuticals, Inc.
  • Merck & Co., Inc.
  • Eli Lilly and Company
  • Novo Nordisk, A/S
  • Corcept Therapeutics, Inc.
  • AstraZeneca

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

143 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
5 out of 5
Explains 5
Courtesy, Respect & Concern 5
Patient Rating of Doctor 5

35 Patient Comments

Reviewed on Jul 26, 2021

Dr P is amazing. I have recommended him to so many people. Very bright, resourceful, comprehensive and caring- physician.

Reviewed on Jul 26, 2021

Dr Pantalone is an amazing doctor. He Is bright, resourceful, compassionate and Comprehensive . I have recommended to more than a few people. CC has a gem there.

Reviewed on Jul 2, 2021

Dr. Pantalone is amazing!

Reviewed on Jul 2, 2021

I recommend Dr. Pantalone to all of my diabetic friends!

Reviewed on Jun 21, 2021

hospitalized Hillcrest hosp needed apt. after discharge but none available then one popped up on My Chart I grabbed it. taken promptly at apt. time Love Dr. Panatalone and his staff. He listens to you and shows genuine concern. His staff is approachable returns phone calls when I have questions. The Best!!!!

Reviewed on Jun 21, 2021

you are very fortunate to have Dr. Pantalone and also Dr. Yuan on staff I have been treated by Dr. Yuan for at least 3 yrs. Many times a yr. for injections in both eyes. Again the best!!!!! He also listens shows concerns and very willing to answer questions great staff there also

Reviewed on Jun 18, 2021

Dr. Pantalone listens and provides exceptional health care. I would recommend him and the ClevelandClinic to everyone.

Reviewed on Jun 11, 2021

Dr. Pantelone has been and is a fantastic Doctor to my medical care. Is always respectful. Answers all my questions. provides excellent care!!

Reviewed on May 24, 2021

He was excellent. Very professional and generous with his time to help me understand my options following a concerning test result. Outstanding interpersonal skills with respect to doctor-patient dialogue about health care next steps and options.

Reviewed on May 7, 2021

Dr pantalone is the most caring and considerate doctor I ever had!

Reviewed on Apr 26, 2021

Very good experience. No complaints. Everyone was very friendly and helpful. Dr Pantalone took his time to listen and did not make me feel rushed or intimidated in any way. Would highly recommend.

Reviewed on Apr 19, 2021

Dr. Pantelone communicates very well and puts me at ease with the symptoms I have been experiencing.

Reviewed on Apr 19, 2021

Dr. Pantalone has been extremely helpful. I have tears in my eyes recalling how he has treated me as a whole person who's worthy of quality medical care. I have referred two people to him, but of course, he wasn't accepting new patients. It makes sense that his calendar is filled with patients. I'm so grateful to have him as my provider. I'm prayerful that he continues being my healthcare provider.

Reviewed on Apr 16, 2021

Dr. Pantalone is the gold standard by which all other care providers should be judged. I like him so much that I keep requesting that he become my PCP, but he says he is prevented from dong so.

Reviewed on Apr 16, 2021

Dr Pantalone rocks. You should give him a salary increase.

Reviewed on Apr 9, 2021

dr pantalone is proline of if not the beat dr I have ever gone to. he always takes time to listen, shows genuine concern and addresses every issue that is brought to his attention. he always comes up with a reasonable plan and sets goals that I feel can be accomplished. I have recommended him to many people and if only he could be cloned!!!! unfortunately he isn't taking new patients. I truly can't say enough about how much his care has helped me over the almost 9 or so years I have been his patient.

Reviewed on Mar 26, 2021

Dr. Pantalone is a great doctor in regards to diabetes. He holds you accountable which is needed for this serious condition.

Reviewed on Mar 22, 2021

Dr. Pantalone is one of my favorite doctors! he takes his time and is thorough with his explanations and also doesn't sugar coat things.

Reviewed on Mar 12, 2021

overall, good. Dr. Pantalone is excellent - the video seevice is bot as good as Zoom or other options. Almost all of the Cleveland Clinic supoort services are inferior to other options - my doctor is superior and rhe only reason I stay with the Cleveland Clinic

Reviewed on Mar 12, 2021

Dr. Pantalone is a superior physician that understands I am an intelligent person that understands my condition - we work as a team to maximize my living experience

Reviewed on Mar 12, 2021

I had a great experience with the doctor. Very helpful and showed he cared for me.

Reviewed on Mar 4, 2021

Extremely good communication by both doctor and staff.

Reviewed on Mar 1, 2021

Dr. Pantalone is an excellent doctor. He takes the time to talk with me, answer all my questions. He is a true professional. the office staff is easy to work with also

Reviewed on Feb 24, 2021

dr pantelone is great

Reviewed on Feb 8, 2021

my overall experience with the Doctor and staff was very good

Reviewed on Jan 29, 2021

"very good" doesnt doesnt describe Dr Pantalone. He would require another category. He is consistently insightful, caring,And absolutely goes the extra mile to do whatever he can for you in an appointment with him. I have recommended him to many people. He could teach many other doctors how things should be done

Reviewed on Jan 29, 2021

Dr. Pantalone has always been excellent at all levels of care. I referred a friend to him, and she thinks highly of his knowledge and professionalism, too.

Reviewed on Jan 22, 2021

excellent doctor very concerned about his patients

Reviewed on Jan 18, 2021

I think Dr. Pantalone is a valued asset to the clinic. I would not hesitate for one second to recommend him to others

Reviewed on Jan 11, 2021

Dr. Pantalone is a fabulous doctor and so knowledgeable! I am thankful for him.

Reviewed on Dec 28, 2020

Dr. Pantalone was the most thorough Dr I have ever had, answered all my questions, we had a great discussion and must if all he turned in his chair to look at me when we did talk about things that means alot

Reviewed on Dec 4, 2020

Dr Pantalone is very professional, caring and knowledgeable about my medical condition. He includes me in discussions and confirms my understanding of treatment.

Reviewed on Nov 2, 2020

Dr. Pantalone is the best doctor at the clinic. I have all the faith in the world in him. He listens to me and makes recommendations for my diabetes and gives me tips on how to live a better healthy lifestyle. I have total confidence in him. He is the best.

Reviewed on Nov 2, 2020

Dr. Pantalone was fantastic. He gave me great options and realistic goals to reduce my A1C . He was very informative and positive with my prognosis and I am excited to achieve the result path he has me workin on.

Reviewed on Nov 2, 2020

*Dr. Pantalone explains things so well and answers my questions quickly on MyChart.

Related Videos Featuring Kevin M. Pantalone, DO

Related Videos Featuring Kevin M. Pantalone, DO

Back to Top