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Department Endocrinology, Diabetes and Metabolism
Primary Location Twinsburg Family Health & Surgery Center
Type of Doctor Adults Only
Languages English
Surgeon No
Twinsburg Family Health & Surgery Center
Primary Location

Twinsburg Family Health & Surgery Center

Specialties & Treatments

Treatment & Services

  • Radioactive Iodine Treatment
  • Thyroid Aspiration
  • Thyroid Ultrasound
  • Thyroid Ultrasound And Biopsy
View all 4 Treatment & Services +

Specialty in Diseases & Conditions

  • Acromegaly
  • Addison's Disease
  • Adrenal disorders
  • Adrenal insufficiency
  • Adrenal Tumors
  • Adrenocortical Carcinoma
  • Adrenoleukodystrophy (ALD)
  • Amenorrhea
  • Androgen Excess
  • Bone Disorders
  • Calcium Disorders
  • Carcinoid Syndrome
  • Conn's Syndrome
  • Cushing's Syndrome
  • Diabetes
  • Diabetes, Gestational
  • Empty sella
  • Endocrine Complications of Pregnancy
  • Endocrine Disorders
  • Endocrine Hypertension
  • Familial Multiple Endocrine Neoplasia
  • Fasting hypoglycemia
  • Flushing Syndromes
  • Galactorrhea
  • Goiter
  • Growth hormone deficiency
  • Growth hormone excess
  • Gynecomastia
  • High Cholesterol
  • Hirsutism
  • Hyperaldosteronism
  • Hyperandrogenism
  • Hypercalcemia
  • Hyperparathyroidism
  • Hyperprolactinemia
  • Hypertension - High Blood Pressure
  • Hyperthyroidism
  • Hypertriglyceridemia
  • Hypocalcemia
  • Hypogonadism
  • Hypoparathyroidism
  • Hypophysitis
  • Hypopituitarism
  • Hypothyroidism
  • Klinefelter Syndrome
  • Mastocytosis
  • McCune-Albright Syndrome
  • Menopause, Male
  • Metabolic Bone Disease
  • Metabolic Diseases
  • Metabolic Syndrome
  • Obesity
  • Osteopenia
  • Osteoporosis
  • Pancreatic Endocrine Tumors
  • Pancreatitis
  • Panhypopituitarism
  • Parathyroid Cancer
  • Parathyroid Disease Description
  • Pheochromocytoma
  • Pituitary Cysts
  • Pituitary Disorders
  • Pituitary stalk lesions
  • Pituitary Tumors
  • Polycystic Ovary Syndrome
  • Primary Hyperaldosteronism
  • Prolactin Excess States
  • Prolactinoma
  • Pseudohypoparathyroidism
  • Reactive hypoglycemia
  • Secondary Hyperparathyroidism
  • Thyroid and pregnancy
  • Thyroid Cancer
  • Thyroid Disease
  • Thyroid Nodule
  • Vitamin D Deficiency
  • Zollinger-Ellison Syndrome
View all 77 Specialties +


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About Kevin M. Pantalone, DO

Dr. Pantalone is a board certified Staff Endocrinologist at Cleveland Clinic in Cleveland, Ohio. He currently serves as the Director of Diabetes Initiatives in the Department of Endocrinology. He previously served as the Director of Clinical Research for the Department of Endocrinology from 2014-2019. Dr. Pantalone is a graduate of Ohio University College of Osteopathic Medicine. He completed his internal medicine residency and endocrinology fellowship at Cleveland Clinic.

He was designated a Fellow of the American College of Endocrinology (FACE) in 2015. His clinical focus is on the glycemic management of type 2 diabetes, as well as the diagnosis and management of low testosterone in men, thyroid disorders, and pituitary tumors. His research interests are related to the adverse effects of diabetes therapies, particularly those related to sulfonylureas. He is also actively involved in health outcomes research using the enterprise-wide electronic health record system at Cleveland Clinic.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Cleveland Clinic
Cleveland, OH USA

Internship - Cleveland Clinic
Cleveland, OH USA

Residency - Cleveland Clinic
Internal Medicine
Cleveland, OH USA

Medical Education - Ohio University College of Osteopathic Medicine
Athens, OH USA

Undergraduate - Kent State University
Kent, OH USA

Additional Training

  • Endocrine Certification in Neck Ultrasound (ECNU)

Professional Highlights

  • Dr. Pantalone has received local and national media attention for research pertaining to adverse outcomes with sulfonylurea therapy.   He has served as the Director of Clinical Research for the Department of Endocrinology, Diabetes & Metabolism at Cleveland Clinic since 2014.  His research ris egularly featured in Healio Endocrine today,  His commentary on recently published studies pertaining to diabetes is featured regularly by Endocrinology Advisor,  He is a member of MD Magazine’s Advisory Board, and serves on numerous institutional, ADA, and AACE committees.


  • Internal Medicine
  • Internal Medicine - Endocrinology, Diabetes and Metabolism

Awards & Honors

  • Appointed member of the steering committee for NN8022-4432, An Obesity Pragmatic ClinicalTrial, 2018
  • Appointed to the American College of Endocrinology (College) Task Force to serve as amember of the ACE CPG Oversight Committee, 2018
  • Nominated by department leadership to complete the “Introduction to Emotional Intelligence” course at the Case Western Reserve Weatherhead School of Management, July, 2018.
  • Featured regularly by Endocrinology Advisor, providing commentary on recently published studies pertaining to diabetes, 2017 to present.
  • Appointed to Research Executive Committee, Cleveland Clinic, 2017 to present
  • Research Information Technology Advisory Board, Cleveland Clinic, 2017 to present
  • Appointed to Patient Access Steering Committee, Cleveland Clinic, 2017 to present
  • Member of MD Magazine’s Advisory Board, 2017 to present
  • Principal Investigator for PIONEER-6: A Trial Investigating the Cardiovascular Safety of Oral Semaglutide in Subjects with Type 2 Diabetes
  • Appointed to the American College of Endocrinology (College) Task Force to Update the AACE Growth Hormone Clinical PracticeGuidelines, 2017
  • Appointed to the American College of Endocrinology to serve as a member of the ACE Scientific Referencing Team (ASRT), 2016
  • Manuscript reviewer for The Lancet, 2016 to present
  • NIH-R01 co-investigator Dynamics of Muscle Mitochondria in Type 2 Diabetes (DYNAMMO T2D).  Roles include advising with subject recruitment and advising with the Standard of Care component of the intervention for the type 2 diabetes group and helping with the screening process (2015-2020).
  • Chosen by the Endocrine Society to participate in the society’s annual media training seminar (2015) to assist the society with endocrine-related media requests
  • Nominated by department leadership to complete the annual “Leading in Health Care” course at Cleveland Clinic, 2015-2016.
  • Fellow of the American College of Endocrinologists (FACE), 2015
  • Guest Editor, J Am Osteopath Assoc. 2015 Apr 1;115(4_suppl):eS3-eS4.Abstract Reviewer, Clinical Diabetes, The Endocrine Society, 2014 
  • Appointed Director of Clinical Research for the Department of Endocrinology, Diabetes & Metabolism at Cleveland Clinic, August of 2014
  • Principal Investigator and Regional Study Leader for DEVOTE: A Trial Comparing Cardiovascular Safety of Insulin Degludec Versus Insulin Glargine in Subjects With Type 2 Diabetes at High Risk of Cardiovascular Events
  • Manuscript reviewer for The New England Journal of Medicine, 2014 to present
  • Manuscript reviewer for The Lancet Diabetes and Endocrinology, 2014 to present
  • Authored an online fellow’s module addressing the diagnosis and treatment of male hypogonadism for the American Association of Clinical Endocrinologists, May 2013
  • Received national media attention for research pertaining to adverse outcomes with sulfonylurea therapy (The Endocrine Society, U.S. News and World Report, Medscape Medical News, etc.)
  • Received local media attention for research pertaining to adverse outcomes with sulfonylurea therapy; featured in Akron Beacon JournalJuly 10, 2012
  • Interviewed by Diabetes Radio/Optimal Clinical regarding my research entitled a href="">The risk of overall mortality in patients with Type 2 diabetes receiving different combinations of sulfonylureas and metformin: a retrospective analysis, March 2012.
  • Cleveland Clinic Endocrinology and Metabolism Institute Research Award Winner, Best Research Presentation, April 2011
  • Chief Fellow, Department of Endocrinology, Diabetes, and Metabolism, Cleveland Clinic, 2010-2011
  • Presidential Poster Competition Winner, The Endocrine Society National Meeting, San Diego, CA, June 2010
  • Cleveland Clinic Endocrinology and Metabolism Institute Research Award Winner, Best Research Presentation, April 2010 
  • Fellow representative for the Cleveland Clinic Diabetes Care Team, a multidisciplinary team of health care providers which meets on a monthly basis to address issues pertaining to diabetes management in the hospital setting, July 2009 to June 2011
  • Cleveland Clinic Internal Medicine Senior Resident of the Year, 2008-2009
  • Cleveland Clinic Peskind Award, Best Clinical or Nonclinical Paper from a Resident in the Division of Medicine, June 2009
  • Cleveland Clinic Resident Research Competition Winner and Internal Medicine Grand Rounds Presentation, Best Internal Medicine Resident Research Project, June 2009
  • Graduated in the top 10% at Ohio University College of Osteopathic Medicine, June 2006
  • Valedictorian of College of Arts and Sciences, Kent State University, May 2002, GPA 4.0
  • Recognized as one of the brightest college students in Northeast Ohio in Northeastern Ohio Live MagazineMay 2002
  • Mary Manchester Award for Superior Scholarship, Leadership and Constructive Citizenship, April 2002
  • Superior Research Award, Lubrizol Corporation and Kent State University, April 2002
  • Phi Beta Kappa National Honors Society, inducted April 2002
  • Golden Key National Honors Society, inducted March 2001


  • The Endocrine Society
  • American Association of Clinical Endocrinologists
  • The American Diabetes Association
Research & Publications

Research & Publications

See publications for Kevin M. Pantalone, DO.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 10/3/2022, Dr. Pantalone has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Consulting and/or Speaking. Dr. Pantalone receives fees of $5,000 or more per year as a paid consultant, speaker or member of an advisory committee for the following companies:

  • Novo Nordisk, A/S
  • Merck & Co., Inc.
  • Eli Lilly and Company
  • Corcept Therapeutics, Inc.
  • Bayer Healthcare Pharmaceuticals, Inc.
  • AstraZeneca

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

129 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
5 out of 5
Explains 4.9
Courtesy, Respect & Concern 5
Patient Rating of Doctor 5

30 Patient Comments

Reviewed on Feb 17, 2023

Dr. Pantalone took care of me as always in the best way as he normally does, and is very considerate and understanding of my issues. Of all the doctors I use at the clinic, he and my primary car physician are absolutely the best I've ever had.

Reviewed on Feb 17, 2023

Dr was very attentive and genuinely concerned. Very knowledgable would highly recommend him

Reviewed on Jan 30, 2023

Dr. Pantalone is an outstanding physician, and I am grateful to receive such good care.

Reviewed on Jan 30, 2023

Dr. Pantalone is a talented physician; I do trust him with my life, his counsel is helping me tremendously.

Reviewed on Jan 30, 2023

Dr. Pantalone and his team Is amazing. They are also so kind and easy to work with.

Reviewed on Jan 30, 2023

I would definitely recommend Dr. Pantalone to anyone in search of an endocrinologist.

Reviewed on Jan 27, 2023

Awesome provider easy to talk to always allows me to be in on decisions

Reviewed on Jan 16, 2023

Dr. Pantalone is a fantastic doctor. He's caring and nice.

Reviewed on Jan 16, 2023

Dr. Pantalone is a caring and compassionate physician. He has provided excellent healthcare for my father and has managed is diabetes in such a way, my dad's medications have been changed and/or eliminated to a point he is in much better state physically and emotionally. Can't say enough good about Dr. Kevin Pantalone.

Reviewed on Jan 16, 2023

Outstanding and caring doctor.

Reviewed on Jan 13, 2023

Outstanding-Dr Pantllone is awesome at communicating with me.

Reviewed on Jan 13, 2023

Dr. Pantalone is very respectful and takes his time to explain your health issues.

Reviewed on Jan 13, 2023

Dr Pantalone is the best!

Reviewed on Jan 9, 2023

Doctor Pantalone is the best!

Reviewed on Jan 9, 2023

Dr Pantalone as you should know, is off of this chart. He is amazing at finding new ways to help and showing genuine concern looking at you as a person not just the illness. If only they were all like him.

Reviewed on Dec 19, 2022

Dr pantalone is great.

Reviewed on Oct 24, 2022

I love Dr. Pantalone, he is a knowledgeable, caring, and professional physician. I have unequal trust and faith in the care I receive from Dr. Pantalone.

Reviewed on Oct 3, 2022

He's an awesome man , he has always had my best interest . I love him as a friend not just my Dr.

Reviewed on Sep 12, 2022

Excellent Care. Dr. Pantelone listens.

Reviewed on Sep 2, 2022

It is really nice to have a provider finally feel like they want what is best for me and advocate for me as a person. Dr. Pantalone is the first doctor to actually feel like they are on my team and want what's best for me.

Reviewed on Aug 29, 2022

No bad experiences with Dr. Pantalone, he always explains everything.

Reviewed on Aug 15, 2022

Dr. Pantalone since my first visit years ago has treated me with the utmost respect, caring and concern. His expertise and vast resourcefulness are greatly appreciated. He's the ultimate professional.

Reviewed on Aug 12, 2022

Dr. Pantalone was very accommodating to my schedule as I was on vacation.

Reviewed on Aug 12, 2022

Dr. Pantalone is the BEST! He cares and I truly trust him.

Reviewed on Jul 25, 2022

Dr. Pantaloons is the best endocrinologist I have ever been tested by!!

Reviewed on Jul 1, 2022

Excellent doctor!

Reviewed on Jul 1, 2022

Awesome hospital, awesome Staff , awesome labs , clean and I love Dr . Kevin patalone

Reviewed on May 9, 2022

GREAT doctor!!

Reviewed on Apr 18, 2022

The doctor I trust the most

Reviewed on Apr 8, 2022

I LOVE Dr Pantelone! He always shows he cares about my care. He has plans ready to discuss with me and is always knowledgeable about the latest technology. He also has has a personal conversation with me and always seems interested in improving my wellbeing.

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