Emergency icon Important Updates
Department Gastroenterology, Hepatology & Nutrition
Primary Location Twinsburg Family Health & Surgery Center
Type of Doctor Adults Only
Languages English
Surgeon No
Locations Specialties & Treatments

Treatment & Services

  • Abnormal Liver Tests
  • Blood Tests
  • Cancer Screening
  • Capsule Endoscopy
  • Colonoscopy
  • Colorectal Cancer Prevention
  • Endoscopic Dilation
  • Endoscopic Treatment Of Strictures
  • Endoscopy
  • Esophageal Dilation
  • Esophagogastroduodenoscopy (EGD)
  • Flexible Sigmoidoscopy
  • Gastroenterology
  • Gastrointestinal Endoscopy
  • Hydrogen Breath Test
  • Percutaneous Endoscopic Gastrostomy (PEG)
  • Proctitis - Care and Treatment
  • Therapeutic Endoscopy
  • Wireless Capsule Endoscopy
View all 19 Treatment & Services +

Specialty in Diseases & Conditions

  • Abdominal Pain
  • Angiodysplasia of Small Bowel
  • Angioectasia
  • Barrett's Esophagus
  • Celiac Disease (Celiac Sprue)
  • Clostridium Difficile Colitis
  • Collagenous Colitis
  • Colon Diseases
  • Colon Polyps
  • Constipation
  • Crohn's Disease
  • Diarrhea
  • Diverticulosis
  • Dysphagia
  • Eosinophilic Esophagitis
  • Eosinophilic Gastroenteritis
  • Esophageal Stricture
  • Esophagitis
  • Fundic Gland Polyps
  • Gas (Digestive)
  • Gastritis
  • Gastroenteritis
  • Gastroesophageal Reflux (GERD)
  • Gastrointestinal (GI) Bleeding
  • Gastrointestinal Diseases
  • General Gastroenterological Disorders
  • Heartburn
  • Helicobacter Pylori
  • Hiatal Hernia
  • Indigestion
  • Inflammatory Bowel Disease (IBD)
  • Iron Deficiency Anemia
  • Irritable Bowel Syndrome (IBS)
  • Lactose Intolerance
  • Liver Disease
  • Microscopic Colitis
  • Obscure Gastrointestinal Bleeding
  • Peptic Ulcer Disease
  • Proctitis
  • Radiation Enteritis
  • Rectal Bleeding
  • Small Bowel Bacterial Overgrowth
  • Stomach Pain
  • Swallowing Disorders
  • Ulcerative Colitis
View all 45 Specialties +


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Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Cleveland Clinic
Cleveland, OH USA

Residency - The Ohio State University Hospitals
Internal Medicine
Columbus, OH USA

Internship - The Ohio State University Hospitals
Internal Medicine
Columbus, OH USA

Medical Education - The Ohio State University College of Medicine and Public Health
Columbus, OH USA

Undergraduate - Miami University
Oxford, OH USA


  • Internal Medicine
  • Internal Medicine - Gastroenterology

Specialty Interests

Capsule Endoscopy, celiac disease, Colon cancer prevention, Colonoscopy, Diagnostic and therapeutic EGD (upper endoscopy) and colonoscopy, Education of Fellows/Residents, Eosinophilic Esophagitis, gastroenterology, gastroesophageal reflux disease, gastrointestinal bleeding and capsule endoscopy, gastrointestinal endoscopy, general gastroenterology, general gastrointestinal disease, GERD, h. pylori infection, IBD including ulcerative colitis and crohn's, inflammatory bowel disease, obscure gastrointestinal bleeding, Ulcerative Colitis, Wireless technology including small bowel capsule endoscopy and BRAVO esophageal pH probe

Research & Publications

Research & Publications

See publications for Luke Weber, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 11/10/2023, Dr. Weber has reported no financial relationship with industry that is applicable to this listing. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

432 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.9 out of 5
Explains 4.8
Courtesy, Respect & Concern 4.9
Patient Rating of Doctor 4.8

62 Patient Comments

Reviewed on Oct 26, 2023

I was so pleased with the Cleveland Clinic in Twinsburg facility and Dr. Weber. All of the nurses and other medical assistants that worked with me were totally excellent. Dr. Weber was excellent and I am so glad to be his patient.

Reviewed on Oct 26, 2023

I would more than willing to recommend both Dr. Weber and Cleveland Clinic to anyone.

Reviewed on Oct 26, 2023

Dr. Weber is AMAZING, I'm very thankful for him

Reviewed on Oct 19, 2023

Dr. Weber and the OR nurse and nurse anesthetist were wonderful.

Reviewed on Oct 18, 2023

Excellent doctor!

Reviewed on Sep 27, 2023

Dr Weber was excellent. He looked me straight in my eyes and answered all questions and was interested in all that I said. So professional and knowledgeable.

Reviewed on Sep 21, 2023

Dr Weber fantastic

Reviewed on Aug 25, 2023

Due to the many blood thinners that I take Dr Weber decided to do the procedure himself and I was very glad about that. I had read that your throat would be sore after the procedure but I felt none of that. In and out very quickly and I thank him for that. Very professional and very thorough I could not have asked for anyone better.

Reviewed on Aug 24, 2023

Dr. Webber was exceptional in his care and his explanations. I really appreciated this bedside manner and his professionalism.

Reviewed on Aug 23, 2023

Dr. Luke Weber is an Excellent and Compassionate Care Provider.

Reviewed on Aug 1, 2023

My experience with Dr. Weber was a very good one. He explained the procedure before and after. Can't say enough about the care he had given me.

Reviewed on Aug 1, 2023

Everything was addressed and handled in a professional way. I was very comfortable with the nurses and Dr Weber

Reviewed on Jul 18, 2023

Dr. Luke Weber was excellent!

Reviewed on Jul 5, 2023

He's an excellent doctor and thorough.

Reviewed on Jun 30, 2023

I have already sent patients to Dr. Weber, and they think he is not only a great doctor but also a great person.

Reviewed on Jun 28, 2023

Dr. Weber always provides very good care. He listens well and comes up with solutions for problems I may have.

Reviewed on Jun 19, 2023

Everyone at the Cleveland Clinic has been amazing and helpful. And Dr. Weber rocks

Reviewed on Jun 7, 2023

Dr Weber and his team were outstanding. They explained everything clearly and were very attentive to my needs throughout.

Reviewed on Jun 7, 2023

Dr Weber is kind and patient and seems to genuinely care about his patients.

Reviewed on Jun 6, 2023

Always a good encounter with Dr. Weber

Reviewed on Jun 1, 2023

Dr. Webber is amazing and listen and answers all questions. I would recommend him to all family and friends.

Reviewed on May 31, 2023

Dr Weber always explains well and addresses and answers thoroughly

Reviewed on May 10, 2023

Dr. Weber is an excellent physician as he takes time to listen to my concerns and he always addresses them. He has been my physician for 13 yrs and he is an excellent clinician. He is very courteous and has great bedside manners. The wait time was not long, and the medical assistant was great as well.

Reviewed on May 10, 2023

Dr. Weber is an excellent physician. He listens and addresses any concerns. He is always Courteous.

Reviewed on May 1, 2023

Dr. Luke Weber is an excellent Gastroenterologist

Reviewed on Apr 28, 2023

Dr. Luke Weber was very thourough with his with questions and procedures.Very professional. Feel I am in very competent hands.

Reviewed on Apr 19, 2023

Dr. Weber is an excellent doctor. Excellent in his knowledge and willingness to explain to you in medical and layman terms. I have already recommended him to family members and friends.

Reviewed on Apr 12, 2023

Dr. Weber and his team were all friendly and professional, would highly recommend him.

Reviewed on Apr 12, 2023

Procedure went smoothly. Dr. Weber and his staff were wonderful and kept me comfortable.

Reviewed on Apr 12, 2023

Dr Weber is excellent the best care ever

Reviewed on Apr 6, 2023

Dr Weber was very attentive and kind

Reviewed on Apr 5, 2023

Dr. Weber is excellent! Worth the wait to have him be my GI physician.

Reviewed on Mar 13, 2023

Dr. Weber is very considerate and he is always answers all your questions and concerns. He gets a 10.

Reviewed on Mar 8, 2023

Dr. Weber always explains my options well and helps me find solutions to issues I'm having.

Reviewed on Mar 7, 2023

Dr. Weber has been my gastroenterologist for 15 years and he is an excellent clinician/physician. I've never had any issues with the scheduling nor the care he provided.

Reviewed on Mar 7, 2023

Dr. Weber has always provided me with excellent care. He is an excellent physician/clinician. He also has the best bedside manners, and always follows up timely should I call with any GI concerns. He explains treatment plans and addresses any concerns that I have at all visits. He's exemplary of providing world class care at its finest.

Reviewed on Mar 1, 2023

Dr. Weber was very courteous and listened. Also answered all of my questions and concerns.

Reviewed on Feb 23, 2023

Dr. Weber seems like a very kind, caring Doctor who is also very professional

Reviewed on Feb 22, 2023

I would definitely recommend Dr Weber. He did a great job explaining everything.

Reviewed on Feb 20, 2023

I'm always comfortable discussing health conditions with Dr Weber. He's very knowledgeable about options and care and exhibits empathy and genuine interest in my care.

Reviewed on Feb 17, 2023

Long wait to see Dr. Weber.

Reviewed on Feb 15, 2023

Need a "not applicable " on the survey. Dr Weber and his team were very professional and caring

Reviewed on Feb 14, 2023

It was a good experience. Considering how backed up doctors are right now, I was very pleased with the timing and every person that I had contact with.

Reviewed on Feb 14, 2023

The entire staff was Great, also this was my first time to meet Dr. Weber, I really liked meeting him, and having him do my procedure.

Reviewed on Feb 9, 2023

I would not want anyone else but Dr Weber to do my procedure He totally understood how anxious I was with what happened on my last colonoscopy 10 yrs ago by a lady doc. It was a horrible experience. Dr Weber was quite the opposite I would recommend him to anyone having a colonoscopy. He is the best

Reviewed on Feb 8, 2023

Dr. Weber was excellent. He listened well and explained things very clearly and concisely. Highly professional.

Reviewed on Feb 6, 2023

Virtual visit worked well. Dr. Weber was very thorough and professional

Reviewed on Feb 6, 2023

Dr. Weber is an excellent physician who discusses options and plans of action

Reviewed on Feb 2, 2023

Doctor Luke Webber and staff were exceptionally kind and helpful in diagnosing and planning a treatment program to resolve issues.

Reviewed on Feb 1, 2023

I was referred to dr Webber years ago by a family member. After a couple of appts with him my condition and quality of life sky rocketed. I saw many specialists over the years but dr Weber has been the best. I refer everybody I can to him.

Reviewed on Jan 30, 2023

Dr. Weber addressed my concerns with care and compassion.

Reviewed on Jan 26, 2023

I travel about 35 miles to get there. Everything for me was very smooth, the caregivers worked together very courteous and respectful of each other and myself. I recommend the Cleveland clinic to everyone, the twinsburg facility is super for getting in and out and the Doctors and Nurses are second to none. They are your best assets to keep the Cleveland clinic on top.

Reviewed on Jan 26, 2023

Great Doctor

Reviewed on Jan 26, 2023

Each person - the doctor, PA - did all the above in a professional manner, listening to me, questioning and responding.

Reviewed on Jan 24, 2023

Dr Weber was very easy and calming to talk to This was my first colonoscopy so I was nervous. Care team was great with everything.

Reviewed on Jan 10, 2023

Dr. Weber is an exceptional physician.

Reviewed on Jan 4, 2023

Dr. Weber took really good care of me. He suggested I get genetic counseling to help with my treatment plan. Thank you so much Dr. Weber!!!

Reviewed on Jan 3, 2023

Dr Weber has a very busy work load to get an early appt.

Reviewed on Dec 28, 2022

My appointments with Dr. Weber and his staff are very good.

Reviewed on Dec 27, 2022

I were not able to get an appointment, but after contacting the doctor, I was called and a very helpful agent scheduled my procedure.

Reviewed on Dec 21, 2022

Excellent physician and staff.

Reviewed on Dec 7, 2022

Dr listened and explained very well.

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