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Department Hematology and Medical Oncology
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English
Surgeon No
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus

Specialties & Treatments

Treatment & Services

  • Benign Hematology
  • Cancer Center
  • Clinical Trials
  • Experimental Therapeutics
  • Medical Oncology
View all 5 Treatment & Services +

Specialty in Diseases & Conditions

  • Acute Myeloid Leukemia
  • Aplastic Anemia
  • Leukemia
  • Leukopenia
  • Lymphoma
  • Myelodysplastic Syndrome (MDS)
  • Myeloma
View all 7 Specialties +


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About Yogen Saunthararajah, MD

Yogen Saunthararajah, MD, is Staff in the Department of Hematologic Oncology and Blood Disorders at Cleveland Clinic, a Professor of Medicine, and Co-Leader of the Developmental Therapeutics Program of the Case Comprehensive Cancer Center.

Dr. Saunthararajah received undergraduate and medical degrees from the University of Wales College of Medicine, and completed medical and surgical internships at University Hospitals of Wales, United Kingdom. Dr. Saunthararajah served as a Captain (Military Medicine) in the Singapore Armed Forces, Singapore.
Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - National Institute of Health - Cancer Institute
Bethesda, MD

Residency - University of Hawaii Queens Medical Center
Internal Medicine
Honolulu, HI

Residency - University of Hawaii Queens Medical Center
Internal Medicine
Honolulu, HI

Internship - University of Hawaii Queens Medical Center
Internal Medicine
Honolulu, HI

Medical Education - University of Wales College of Medicine, Cardiff University

Additional Training

  • Completed course work for Duke/NIH Master's in Clinical Research

Professional Highlights

  • Service on National Institutes of Health, Veterans Administration, and Department of Defense Grant Review Committees and Advisory Boards
  • Awarded grants by the National Institutes of Health, the Department of Defense and the Leukemia and Lymphoma Society


  • Internal Medicine - Medical Oncology
  • Internal Medicine - Hematology

Specialty Interests

Acute myeloid leukemia, myelodysplastic syndrome, sickle cell disease/anemia, thalassemia, leukemia, benign hematology, myelodysplasia, cancer, leukopenia, aplastic anemia

Awards & Honors

  • Graduated with Distinctions in Medicine and Surgery
  • Received Excellence Awards from the University of Hawaii and University of Illinois at Chicago
  • Grant awards from the National Institutes of Health and U.S. Department of Defense

Innovations & Patents

  • Patents pending for unique approaches to non-cytotoxic (non-toxic), epigenetic therapy in cancer, sickle cell disease and thalassemia. The cancer treatments are intended to be non-toxic and address the problem of p53-deletions in cancer. 


  • American Society of Hematology
  • American Association of Cancer Research
Research & Publications

Research & Publications

See publications for Yogen Saunthararajah, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 4/23/2024, Dr. Saunthararajah has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Royalty Payments. Dr. Saunthararajah receives or has the right to receive royalty payments for inventions or discoveries commercialized through the companies shown below:

  • University of Illinois, Chicago
  • EpiDestiny, Inc.
  • Novo Nordisk, A/S

Equity Dr. Saunthararajah owns stock or stock options in the following companies for activities as a founder, inventor, discover, developer:

  • EpiDestiny, Inc.

Fiduciary Role. Dr. Saunthararajah serves in a fiduciary capacity, such as an elected officer, director or chief medical officer, for the following companies or other entities:

  • EpiDestiny, Inc.
  • Treebough Therapies, LLC

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

55 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.7 out of 5
Explains 4.7
Courtesy, Respect & Concern 4.7
Patient Rating of Doctor 4.7

14 Patient Comments

Reviewed on Jun 14, 2024

Dr Yogen and staff always responsive and I am thankful for ability to schedule appointments in a timely manner.

Reviewed on Jun 14, 2024

I have had exceptional care. I am very thankful for Dr. Yogen. I have a lot of trust and confidence in his care for me. His knowledge is exceptional.

Reviewed on May 17, 2024

Dr. Yogan is an excellent doctor and has done an amazing job keeping me healthy. So glad to have him helping me.

Reviewed on Apr 19, 2024

Dr. Yogen is and has always been honest, forthcoming and kind.

Reviewed on Feb 7, 2024

Dr Yogen is fantastic! He is very thorough and explains well. He's a very kind and compassionate doctor. I have a lot of respect for his knowledge and expertise

Reviewed on Nov 22, 2023

Dr Yogen is a caring, compassionate and thorough doctor. I feel very lucky to have him caring for me. I am confident in his decisions. He explains very well

Reviewed on Nov 17, 2023

I really like Dr. Yogen and his excellent staff.

Reviewed on Sep 20, 2023

Excellent, he takes time to listen and takes the appropriate measures; and then he gets his nurse to check on me. I am extremely satisfied with my doctor.

Reviewed on Sep 15, 2023

Doctor was incredibly. Really explained throughly

Reviewed on Aug 30, 2023

Dr Yogen is an outstanding doctor!

Reviewed on Aug 9, 2023

Provider is brilliant but does not lke to answer questions about my disease.

Reviewed on Jul 21, 2023

Consistently good experience with contacting Clinic for appointments. When contacting Dr Yogen's office, my calls are always returned from staff or Dr Yogen.

Reviewed on Jul 21, 2023

Dr Yogen has always been very informative, kind and willing to answer my questions.

Reviewed on Jul 5, 2023

Dr Yogen is a very caring physician. He always takes time to explain my care and answer my questions.

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