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Department Ophthalmology
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English
Surgeon Yes
Locations Specialties & Treatments

Treatment & Services

  • Anterior Segment Surgery
  • Cataract Evaluations
  • Cataract Implant Surgery
  • Cataract Surgery
  • Clinical Drug Trials
  • Clinical Trials
  • Cornea Transplant
  • Corneal Collagen Cross-Linking
  • Corneal Surgery
  • Corneal Transplant
  • Corneal Transplantation (penetrating And Lamellar Keratoplasty And Dsaek)
  • Descemet Membrane Endothelial Keratoplasty (DMEK)
  • Descemet's Stripping Automated Endothelial Keratoplasty (DSAEK)
  • Descemet's Stripping Endothelial Keratoplasty (DSEK)
  • Femtosecond Cataract Surgery
  • Laser Cataract Surgery
  • Laser Eye Surgery
  • Laser Vision Correction
  • LASIK (Laser in situ Keratomileusis)
  • Lens Implant
  • Multifocal Intraocular Lenses
  • Non-Invasive Diagnostic Testing
  • Noninvasive Ocular Ultrasound
  • Ophthalmic Surgery
  • Ophthalmology
  • Optical Coherence Tomography
  • Phacoemulsification
  • Photorefractive Keratectomy (PRK) Eye Surgery
  • Refractive Cataract Surgery
  • Refractive Lens Exchange
  • Refractive Surgery
View all 31 Treatment & Services +

Specialty in Diseases & Conditions

  • Anterior Ocular Disease
  • Cataract and Intraocular Lens Implantation in Cataract Surgery
  • Cataracts
  • Cataracts and Cataract Surgery
  • Cornea Ulcer
  • Corneal Abrasion
  • Corneal Disease
  • Corneal Scar
  • Dry Eyes
  • Iridocyclitis
  • Keratoconus
  • Lens Dislocation
  • Myopia (Nearsightedness)
  • Ocular Injuries
  • Refractive Errors
  • Refractive Surgery Complications
View all 16 Specialties +


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About William Dupps, MD, PhD

William J. Dupps Jr., MD, MS, PhD, a native of Catawba Island, Ohio, joined the staff of Cleveland Clinic in 2006 and has appointments in Ophthalmology, Biomedical Engineering and Transplantation. His academic appointments include Professor of Ophthalmology at the Cleveland Clinic Lerner College of Medicine and Professor of Biomedical Engineering at Case Western Reserve University. After graduating with an undergraduate degree in chemical Engineering from Purdue University, he completed his master’s and doctoral degrees in Biomedical Engineering at The Ohio State University, where he also earned his medical degree with honors as a fellow in the Medical Scientist Training Program. He completed an ophthalmology residency at the University of Iowa Department of Ophthalmology and Visual Sciences, a research fellowship in ocular gene therapy at the National Eye Institute, and a two-year Cornea and Refractive Surgery Fellowship at the Cole Eye Institute. He specializes in refractive surgery, corneal transplantation, and cataract surgery.

With research support from sources such as the National Keratoconus Foundation, the National Institutes of Health, and Research to Prevent Blindness, Dr. Dupps leads an interdisciplinary research team in the Ocular Biomechanics and Imaging Laboratory at the Cole Eye Institute focused on the biomechanics of keratoconus and methods for improving refractive surgery outcomes with patient-specific computational modeling. Dr. Dupps is listed in Who’s Who in Medicine and Healthcare, Who’s Who in Science and Engineering, and America’s Top Ophthalmologists. His contributions have been recognized by his peers through membership in the American Ophthalmological Society and honors such as the Kritzinger Award and a Senior Achievement Award from the International Society of Refractive Surgery and the American Academy of Ophthalmology.  He was named Teacher of the Year by the residents of the Cole Eye Institute in 2010 and is the Director of Cole Eye Institute’s cornea and refractive surgery fellowship training program.

Dr. Dupps is Editor of the Journal of Cataract & Refractive Surgery, a leading journal in the field of anterior segment eye surgery, and has authored numerous journal articles and book chapters. He is named on several patents and received the Cleveland Clinic’s first Early Career Innovation Award in 2008.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Cleveland Clinic
Cornea & Refractive Surgery
Cleveland, OH USA

Residency - University of Iowa College of Medicine
Iowa City, IA USA

Internship - Indiana University School of Medicine
Transitional Medicine
Indianapolis, IN USA

Medical Education - The Ohio State University College of Medicine and Public Health
Columbus, OH USA

Medical Education - The Ohio State University College of Medicine and Public Health
Biomedical Engineering
Columbus, OH USA

Graduate School - The Ohio State University
Biomedical Engineering
Columbus, OH USA

Undergraduate - Purdue University
Chemical Engineering
West Lafayette, IN USA

Professional Highlights

  • Editor, Journal of Cataract & Refractive Surgery
  • Principle Site Investigator, NIH/NEI Multi-Center Genetic Study of Fuchs’ Dystrophy   
  • Research to Prevent Blindness Career Development Award
  • NIH K12/KL2 Multidisciplinary Clinical Research Career Development Programs Grant
  • Cleveland Clinic Foundation Innovations Grants
  • Oral Examiner, American Board of Ophthalmology
  • American Academy of Ophthalmology: Practicing Ophthalmologist Curriculum (POC) Refractive Management/Intervention Panel & Committee for Research, Regulatory & External Scientific Relations


  • Ophthalmology

Specialty Interests

corneal transplantation & cataract, Refractive Surgery

Awards & Honors

  • Omicron Delta Kappa National Leadership Honor Society
  • S.J. Roessler Memorial Research Scholarship Award
  • Landacre Society Research Honorary
  • Latin American Studies Program Grant
  • American Medical Student Association International Health Travel Grant
  • Graduate Student Alumni Research Award, The Ohio State University
  • Presidential Fellowship, The Ohio State University Graduate School
  • Alpha Omega Alpha Honor Medical Society
  • Phi Kappa Phi
  • The Nation’s Deans List
  • Eli Alcorn Prize in Ophthalmology, The Ohio State University
  • National Eye Institute Travel Grant, ARVO
  • The Fischbach Medical Scholarship, Delta Tau Delta Education Foundation
  • Marquis Who’s Who in Medicine and Healthcare
  • Cleveland Clinic Innovator Award
  • Marquis Who’s Who in Science and Engineering
  • America’s Top Ophthalmologists, Consumers’ Research Council of America
  • Academic Hall of Fame, Port Clinton High School, Port Clinton, Ohio
  • Early Career Innovation Award, Cleveland Clinic
  • Distinguished Alumni Lecture, University of Iowa Department of Ophthalmology & Visual Sciences
  • Best Doctors in America, Best Doctors Inc.
  • Teacher of the Year, Cole Eye Institute, Cleveland Clinic
  • Distinguished Alumnus Award, College of Engineering, The Ohio State University
  • Cambridge Who’s Who Registry among Executives, Professionals and Entrepreneurs
  • Cleveland’s Top Doctors, Cleveland Magazine
  • Achievement Award, American Academy of Ophthalmology

Innovations & Patents

  • Roberts C, Dupps WJ, Katsube N. “Methods and instruments for refractive ophthalmic surgery.” US Patent 20030208190. Licensed by Bausch & Lomb Surgical. Published Nov. 3, 2003
  • Roberts C, Dupps WJ, Katsube N. “System for refractive ophthalmic surgery.” European Patent Office 05013025.1
  • Dupps WJ, Rollins AM, Ford M. Method for measuring biomechanical properties in an eye. Patent filed May 2006, issued May 3, 2011 as US 7935058 B2
  • Krueger RR, Dupps WJ, Trokel SL, Thornton IL. Method for altering optic nerve head and scleral stiffness. US Provisional Patent Application No. 60/921,317, filed on April 2, 2007
  • Dupps WJ, Sinha Roy A. Computational model of the eye. US Provisional Patent Application 61047179 filed April 23, 2008


  • Association for Research in Vision and Ophthalmology, Cornea Section
  • American Academy of Ophthalmology
  • International Society of Refractive Surgery
  • American Society of Cataract and Refractive Surgery
  • International Society of Optical Engineering (SPIE)
  • Cleveland Ophthalmological Society
  • Society for Clinical and Translational Science
Research & Publications

Research & Publications

See publications for William Dupps, MD, PhD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 9/22/2022, Dr. Dupps has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Royalty Payments. Dr. Dupps receives or has the right to receive royalty payments for inventions or discoveries commercialized through the companies shown below:

  • OptoQuest, Inc.

Right to Future Distribution of Cleveland Clinic Financial Interest. Dr. Dupps may receive future financial benefits from the Cleveland Clinic for inventions or discoveries commercialized through the companies shown below:

  • OptoQuest, Inc.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

211 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.9 out of 5
Explains 4.9
Courtesy, Respect & Concern 4.9
Patient Rating of Doctor 4.9

41 Patient Comments

Reviewed on Mar 23, 2023

Dr. Duchs very thorough.

Reviewed on Mar 23, 2023

Dr. Dupps has been amazing. He has made the process and experience at CCF amazing! Thank you, and do whatever you can to keep him!

Reviewed on Mar 23, 2023

Dr. Dupps has been an amazing physician. Thank you for everything you have done.

Reviewed on Mar 16, 2023

Dr Dupps and Marcella were excellent in guiding you through the actual procedure. Felt more like a guided light show than medical procedure. Very good, thoughtful and patient-oriented care.

Reviewed on Mar 13, 2023

I was treated like family, would highly recommend (and already have). Procedure was thoroughly explained along with options and risks. I feel completely confident in my Health Care Provider

Reviewed on Mar 9, 2023

Dr. Dupps is an amazing doctor. Kept me informed throughout the entire procedure and explained every step of the process.

Reviewed on Mar 9, 2023

Dr. Dupps os the best!

Reviewed on Mar 7, 2023

Dr Dupps is a wonderful provider, as well as a great person. When you're going in to have a procedure such as this, one that can be a little worrisome, he is very laid-back easy to talk to and makes you feel comfortable. I have already recommended other coworkers to see him.

Reviewed on Feb 23, 2023

Dr Dupps was GREAT

Reviewed on Feb 23, 2023

Dr. Dupps is worth the long wait to be seen.

Reviewed on Feb 23, 2023

Dr. Dupps is an amazing provider and totally worth the delayed appointments, long wait times in clinic, and other negative issues that often occur.

Reviewed on Feb 9, 2023

Dr Dupps is excellent, top notch. I would wait for hours at clinic to see him, if necessary. His care is superb, the very best. If I need surgery eventually, I want Dr Dupps.

Reviewed on Feb 9, 2023

Dr. Dupps is by far your best assets He gets a solid 5

Reviewed on Feb 7, 2023

This was my first visit with Dr. Dupps; he definitely lived up to his reputation. Dr. Dupps explains things in such an excellent way that it is easy to follow and understand. He is also very gentle and courteous, making it easy for a patient to feel at ease and ask questions.

Reviewed on Feb 7, 2023

Dr. Dupp's was absolutely amazing from start to finish with my procedure. He explained everything very thoroughly and I would recommend him to everyone.

Reviewed on Feb 2, 2023

We discussed results post surgery, my experience at the surgery. Was able to express my tremendous appreciation for the physician and his team helping me to become at ease with this scary to me procedure. I am utterly grateful. Discussed possibilities for next steps.

Reviewed on Jan 26, 2023

Very confident and comfortable with Dr Dupps. Extraordinary doctor

Reviewed on Jan 26, 2023

I was scheduled 5 months out-April was the first available-but the scheduler asked If I wanted to be added to the cancellation list. I said yes, was called, and saw Dr. Dupps in January.

Reviewed on Jan 26, 2023

Dr. Dupps is excellent in every respect.

Reviewed on Jan 17, 2023

Dr. Dupps is super approachable and knowledgeable.

Reviewed on Jan 12, 2023

Every staff member we met was pleasant. Very helpful & cheerful. They put me at ease. Dr Dupps isAn amazing physician!! He is thorough, kind & Educates me on my Fuchs Dystropia & what to do to prepare for the future if things get worse in my right eye there is surgical repair.

Reviewed on Jan 12, 2023

Dr Dupps was very thorough in explaining exactly what was happening at all times during the procedure, and what I should expect during the recovery period.

Reviewed on Jan 9, 2023

Dr. Dupps was outstanding. He far exceeded my expectations.

Reviewed on Jan 9, 2023

Unfortunately Dr. Dupps had to give me some very unexpected bad news at my lasik evaluation. He had such empathy and really explained everything gently and in a way I could understand. He made the best of a bad experience and I appreciated it very much.

Reviewed on Jan 4, 2023

Dr.Dupps has a great staff. I have the utmost respect for him and his staff. Your general appointment process is mediocre at best.

Reviewed on Jan 3, 2023

Dr. Dupps and the team are first class. He made me feel comfortable with what the procedure would be, great consultation on what needed done, and amazing follow up after the procedure.

Reviewed on Dec 22, 2022

Dr. Dupps responds well to medical questions

Reviewed on Dec 22, 2022

Dr. Dupps was exceptional.

Reviewed on Dec 22, 2022

Great experience with Dr. Dupps.

Reviewed on Nov 17, 2022

Dr Dupps was wonderful during my evaluation and during my procedure. Walked me through each step and prepares me for what was to come next. Dr Dupps and team did a wonderful job!

Reviewed on Nov 17, 2022

Dr Dupps corrected a misaligned cataract surgery. His skill at laser surgery corrected my vision. Appreciated his expertise. My original cataract surgeon did nothing to acknowledge nor correct the lens that was 38 degrees off alignment. She told me no one just looks out of one eye when I told her my vision was blurred. I sought another opinion.

Reviewed on Nov 17, 2022

Dr. Dupps is a wonderful refractive surgeon and physician. It was a great experience.

Reviewed on Nov 10, 2022

Great MD with very limited appointments Worth the wait

Reviewed on Nov 10, 2022

Dr.Dupps is the nicest doctor I have ever went to.

Reviewed on Nov 8, 2022

Dr Dupps Was very courteous, down to earth, and explained everything very well

Reviewed on Nov 3, 2022

Dr. Dupps was very thorough and took the time to answer all of my questions.

Reviewed on Oct 4, 2022

Very knowledgeable and helpful doctor. The staff was very friendly and helpful as well.

Reviewed on Sep 28, 2022

Dr Dupps' is a wonderful eye doctor!! Very caring and explains things in depth and takes his time with his patients.

Reviewed on Sep 8, 2022

Dr Dupps was awesome! Easy to take too!

Reviewed on Sep 8, 2022

Dr Dupps is in demand for all the right reasons. He is honest about his availability and does all a person can do to be accommodating

Reviewed on Jul 19, 2022

Dr. Dupps made me feel so comfortable during my LASIK procedure! He's the best! So calming and friendly

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