Department Ophthalmology
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English
Surgeon Yes
Locations Specialties & Treatments

Treatment & Services

  • Cataract Surgery
  • Corneal Surgery
  • Corneal Transplant
  • Corneal Transplantation (penetrating And Lamellar Keratoplasty And Dsaek)
  • Laser Vision Correction
  • Ophthalmic Surgery
  • Ophthalmology
  • Refractive Surgery
View all 8 Treatment & Services +

Specialty in Diseases & Conditions

  • Cataracts
  • Corneal Disease
View all 2 Specialties +


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About William Dupps, MD, PhD

William J. Dupps Jr., MD, MS, PhD, a native of Catawba Island, Ohio, joined the staff of Cleveland Clinic in 2006 and has appointments in Ophthalmology, Biomedical Engineering and Transplantation. His academic appointments include Professor of Ophthalmology at the Cleveland Clinic Lerner College of Medicine and Professor of Biomedical Engineering at Case Western Reserve University. After graduating with an undergraduate degree in chemical Engineering from Purdue University, he completed his master’s and doctoral degrees in Biomedical Engineering at The Ohio State University, where he also earned his medical degree with honors as a fellow in the Medical Scientist Training Program. He completed an ophthalmology residency at the University of Iowa Department of Ophthalmology and Visual Sciences, a research fellowship in ocular gene therapy at the National Eye Institute, and a two-year Cornea and Refractive Surgery Fellowship at the Cole Eye Institute. He specializes in refractive surgery, corneal transplantation, and cataract surgery.

With research support from sources such as the National Keratoconus Foundation, the National Institutes of Health, and Research to Prevent Blindness, Dr. Dupps leads an interdisciplinary research team in the Ocular Biomechanics and Imaging Laboratory at the Cole Eye Institute focused on the biomechanics of keratoconus and methods for improving refractive surgery outcomes with patient-specific computational modeling. Dr. Dupps is listed in Who’s Who in Medicine and Healthcare, Who’s Who in Science and Engineering, and America’s Top Ophthalmologists. His contributions have been recognized by his peers through membership in the American Ophthalmological Society and honors such as the Kritzinger Award and a Senior Achievement Award from the International Society of Refractive Surgery and the American Academy of Ophthalmology.  He was named Teacher of the Year by the residents of the Cole Eye Institute in 2010 and is the Director of Cole Eye Institute’s cornea and refractive surgery fellowship training program.

Dr. Dupps is Associate Editor of the Journal of Cataract & Refractive Surgery, a leading journal in the field of anterior segment eye surgery, and has authored numerous journal articles and book chapters. He is named on several patents and received the Cleveland Clinic’s first Early Career Innovation Award in 2008.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Cleveland Clinic
Cornea & Refractive Surgery
Cleveland, OH USA

Residency - University of Iowa College of Medicine
Iowa City, IA USA

Internship - Indiana University School of Medicine
Transitional Medicine
Indianapolis, IN USA

Medical Education - The Ohio State University College of Medicine and Public Health
Columbus, OH USA

Medical Education - The Ohio State University College of Medicine and Public Health
Biomedical Engineering
Columbus, OH USA

Graduate School - The Ohio State University
Biomedical Engineering
Columbus, OH USA

Undergraduate - Purdue University
Chemical Engineering
West Lafayette, IN USA

Professional Highlights

  • Associate Editor, Journal of Cataract & Refractive Surgery
  • Principle Site Investigator, NIH/NEI Multi-Center Genetic Study of Fuchs’ Dystrophy   
  • Research to Prevent Blindness Career Development Award
  • NIH K12/KL2 Multidisciplinary Clinical Research Career Development Programs Grant
  • Cleveland Clinic Foundation Innovations Grants
  • Oral Examiner, American Board of Ophthalmology
  • American Academy of Ophthalmology: Practicing Ophthalmologist Curriculum (POC) Refractive Management/Intervention Panel & Committee for Research, Regulatory & External Scientific Relations


  • Ophthalmology

Specialty Interests

corneal transplantation & cataract, Refractive Surgery

Awards & Honors

  • Omicron Delta Kappa National Leadership Honor Society
  • S.J. Roessler Memorial Research Scholarship Award
  • Landacre Society Research Honorary
  • Latin American Studies Program Grant
  • American Medical Student Association International Health Travel Grant
  • Graduate Student Alumni Research Award, The Ohio State University
  • Presidential Fellowship, The Ohio State University Graduate School
  • Alpha Omega Alpha Honor Medical Society
  • Phi Kappa Phi
  • The Nation’s Deans List
  • Eli Alcorn Prize in Ophthalmology, The Ohio State University
  • National Eye Institute Travel Grant, ARVO
  • The Fischbach Medical Scholarship, Delta Tau Delta Education Foundation
  • Marquis Who’s Who in Medicine and Healthcare
  • Cleveland Clinic Innovator Award
  • Marquis Who’s Who in Science and Engineering
  • America’s Top Ophthalmologists, Consumers’ Research Council of America
  • Academic Hall of Fame, Port Clinton High School, Port Clinton, Ohio
  • Early Career Innovation Award, Cleveland Clinic
  • Distinguished Alumni Lecture, University of Iowa Department of Ophthalmology & Visual Sciences
  • Best Doctors in America, Best Doctors Inc.
  • Teacher of the Year, Cole Eye Institute, Cleveland Clinic
  • Distinguished Alumnus Award, College of Engineering, The Ohio State University
  • Cambridge Who’s Who Registry among Executives, Professionals and Entrepreneurs
  • Cleveland’s Top Doctors, Cleveland Magazine
  • Achievement Award, American Academy of Ophthalmology

Innovations & Patents

  • Roberts C, Dupps WJ, Katsube N. “Methods and instruments for refractive ophthalmic surgery.” US Patent 20030208190. Licensed by Bausch & Lomb Surgical. Published Nov. 3, 2003
  • Roberts C, Dupps WJ, Katsube N. “System for refractive ophthalmic surgery.” European Patent Office 05013025.1
  • Dupps WJ, Rollins AM, Ford M. Method for measuring biomechanical properties in an eye. Patent filed May 2006, issued May 3, 2011 as US 7935058 B2
  • Krueger RR, Dupps WJ, Trokel SL, Thornton IL. Method for altering optic nerve head and scleral stiffness. US Provisional Patent Application No. 60/921,317, filed on April 2, 2007
  • Dupps WJ, Sinha Roy A. Computational model of the eye. US Provisional Patent Application 61047179 filed April 23, 2008


  • Association for Research in Vision and Ophthalmology, Cornea Section
  • American Academy of Ophthalmology
  • International Society of Refractive Surgery
  • American Society of Cataract and Refractive Surgery
  • International Society of Optical Engineering (SPIE)
  • Cleveland Ophthalmological Society
  • Society for Clinical and Translational Science
Research & Publications

Research & Publications

See publications for William Dupps, MD, PhD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 9/4/2019, Dr. Dupps has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Consulting and/or Speaking. Dr. Dupps receives fees of $5,000 or more per year as a paid consultant, speaker or member of an advisory committee for the following companies:

  • Alcon, Inc.
  • Avedro, Inc.

Royalty Payments. Dr. Dupps receives or has the right to receive royalty payments for inventions or discoveries commercialized through the companies shown below:

  • OptoQuest, Inc.

Right to Future Distribution of Cleveland Clinic Financial Interest. Dr. Dupps may receive future financial benefits from the Cleveland Clinic for inventions or discoveries commercialized through the companies shown below:

  • OptoQuest, Inc.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

199 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.9 out of 5
Explains 4.9
Listens 5
Courtesy, Respect & Concern 4.9
Knows Medical History 5
Time Spent with Patient 4.9
Patient Rating of Doctor 4.9

33 Patient Comments

Reviewed on Sep 9, 2019

Dr. Dupps is the finest doctor that I have ever experienced. Despite the large number of patients that I am sure he treats, he always make me feel as though I am a patient that he remembers and respects. I absolutely recommend Dr Dupps and the Cole Eye Institute to everyone who is interested in receiving the finest eye care.

Reviewed on Aug 9, 2019

Dr. Dupps was wonderful and explained everything thoroughly. He answered all questions and I did not feel rushed!

Reviewed on Aug 8, 2019

Dr Dupps is amazing. It isn't just his ability as a surgeon - which is amazing but how kind, considerate, and caring he is to his patients. He makes you feel at ease even when you are sitting on his operating table. He will always have my recommendation!

Reviewed on Aug 1, 2019

I truly admire Dr Dupps as a eye specialist and as a person.

Reviewed on Jul 18, 2019

Dr. Dupps has been one of the most amazing doctors I have had thus far. I had a severe Lasik complication at a different institute and he not only corrected it, but did so well that my complication eye is now my better vision eye. He was attentive and caring throughout every step of the process. I don't know where I'd be (or how I'd see) without him. I have highly recommended him and the Clinic to anyone who wants Lasik based on the superior service I received on my flap lift surgery.

Reviewed on Jul 16, 2019

Kim was terrific in assisting me with my insurance and scheduling. Dr. Dupps is a class-act. He's such a gem of a doctor!

Reviewed on Jul 16, 2019

Dr. Dupps is a top-doc perhaps one of the top three I've ever encountered.

Reviewed on Jul 11, 2019

we had very good experience at Cole Eye, from the Red coat , the valet service to all who we met with along the way. Dr Dupps is very kind, caring and makes you feel at ease. I have referred people to him.

Reviewed on Jun 13, 2019

Dr. Dupes is very likable and easy to talk with.

Reviewed on Jun 13, 2019

It was worth the wait to see Dr. Dupps! He is obviously knowledgeable. Great "bedside" manor. Such a pleasant & positive person.

Reviewed on Jun 4, 2019

My experience with Dr Marcellus and Dr Krueger (both lens replacement surgeries) and Dr Dupps have all been wonderful. They were all great listeners and willing to chat at length about any of my concerns and or questions. I would happily recommend all of these doctors.

Reviewed on May 21, 2019

This was my first visit with the doctor and I am very pleased that he was recommended to me

Reviewed on May 21, 2019

Dr. Dupps is an excellent doctor. He is very courteous and kind and made me feel very comfortable. He took the time to listen to my concerns and was great at explaining everything.

Reviewed on May 16, 2019

Dr Dupps is super and the visits to your clinic are too. Epic My Chart is fantastic

Reviewed on May 16, 2019

I absolutely love the customer service and the availability of Dr.Dupps he makes me feel like family rather then a patient. the staff at cole eye institute are amazing!!

Reviewed on May 16, 2019

I was handled in a very professional manner . In addition to Dr. Dupp's superb talent as a surgeon , his personal demeanor was extremely kind and cosideraate .

Reviewed on Apr 18, 2019

Dr. Dupps has excellent bedside manner and is an exceptional doctor.

Reviewed on Apr 16, 2019

Dr Dupps was terrific. Listened and provided great counsel.

Reviewed on Apr 16, 2019

Great Experience. Would recommend Dr Dupps in the future.

Reviewed on Apr 12, 2019

I originally reached out to Dr Dupp's on 4/11 leaving a message on the portal. His assistant, Elaine, contacted me a short time later, coordinated discussions with the doctor and scheduled an appointment with Dr. Dupp's for the following morning, 4/12. I can't say enough about Dr. Dupp's. He is extremely professional, an expert in his field, personable, calming and explains one's condition in a manner which non-professionals understand.

Reviewed on Apr 12, 2019

Please refer to my previous comments. in addition, I travel 2 1/2 hours to see Dr Dupp's. I can't say enough good things about him and will not see another doctor unless absolutely necessary. I've recommended him to several people.

Reviewed on Mar 28, 2019

Dr Dupps is an excellent doctor being very kind and considerate

Reviewed on Feb 28, 2019

Dr. Dupps was nothing short of AMAZING! he was so kind and he took his time to answer ALL OF MY questions my main concern was insurance and not only did he talk to me about a plan b if my procedure was not covered but he said he would personally speak to office staff that took care of things like billing understanding how afraid i was and heading an actual conversation with me about how we could fix the problem really ment a lot this Dr. clearly has a passion for what he does and compassion for other people he made sure i knew what to expect and i knew i was in GREAT HANDS and oh my goodness miss Latrice checked me in now she was a sweetheart my husband and i were told alot of useful info from her as well she was the first to see me so all my nervousness kinda poured out on her but for every worry we had SHE HAD FACTS oh my goodness if it had not been for her i dont think my head would have been clear enough to focus on my most important questions for the doctor but over all this lady was so nice she made us feel like we were talking to a Family member

Reviewed on Feb 27, 2019

Dr. Dupps was absolutely fantastic. I had an incredible experience with him and his office, and have already recommended him to several people.

Reviewed on Feb 8, 2019

Both Dr Dupps and his assistant were top notch.

Reviewed on Feb 7, 2019

In all my years I don't think I've ever had a more kind and friendly Doctor. I love the time he has given me explaining so carefully all my concerns about my corneal surgery. he's always very professional yet has a sense of fun and humor. young docs need to shadow him to learn how to respectfully care for their patients. he's awesome

Reviewed on Jan 23, 2019

Dr. Dupps, and his fellow, Dr. Ma, were both approachable and eminently knowledgeable. Not a single note of condescension, which, in my book, goes a long way.

Reviewed on Jan 10, 2019

It is always nice to see Dr. Dupps.

Reviewed on Dec 18, 2018

I have had a great experience coming to the Cole Eye Institute. Dr. Dupps is one of the nicest, most patient and best doctor I've ever been to.

Reviewed on Nov 8, 2018

I have been coming to the Clinic for over 10 years seeing the same provider and have never had a problem with my care

Reviewed on Nov 8, 2018

Dr Dupps is an excellent physician. He's very kind and knowledgeable and even though he's extremely busy he always makes you feel he has all the time in the world to discuss your concerns

Reviewed on Oct 18, 2018

Dr. Dupps is THE best.

Reviewed on Oct 18, 2018

Dr. Dupps is one of the most caring, authentic, compassionate doctors I have visited. He is always very professional, yet personable. I would send all my family and friends to the Cole Eye Inst. to see Dr. Dupps and his staff anytime.

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