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Department Rheumatologic and Immunologic Disease
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English
Surgeon No
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus

Specialties & Treatments

Treatment & Services

  • Adult Rheumatology
  • Immunotherapy
  • Infusion Therapy
  • Infusions of Biologic Agents on Site
  • Medication Management
  • Musculoskeletal Evaluation
  • Musculoskeletal Medicine
  • Rheumatology
View all 8 Treatment & Services +

Specialty in Diseases & Conditions

  • Arthritis of the Knee
  • Gout
  • Gout Related Arthropathies
  • Lupus
View all 4 Specialties +


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About Brian Mandell, MD, PhD

Brian Mandell, MD, PhD, is board-certified in internal medicine and rheumatology. He is Director of Scholarly Activities of the Internal Medicine Residency Program at Cleveland Clinic, and serves on the Clinic's Board of Governors, the Graduate Medical Education Council, Continuing Health Sciences Education Committee, and Education Governing Group.

Dr. Mandell is also Editor-in-Chief, Cleveland Clinic Journal of Medicine.
Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Hospital of the University of Pennsylvania
Philadelphia, PA USA

Residency - Hospital of the University of Pennsylvania
Internal Medicine
Philadelphia, PA USA

Internship - Hospital of the University of Pennsylvania
Internal Medicine
Philadelphia, PA USA

Medical Education - New York University School of Medicine
New York, NY USA

Medical Education - Washington University School of Medicine
St. Louis, MO USA

Undergraduate - Washington University
St. Louis, MO USA

Additional Training

  • Stanford University Clinical Teaching Faculty Development Program

Professional Highlights

  • Editor, Rheumatology and Allergy Sections, The Merck Manual (home and professional editions)
  • Chair of Annual Scientific Meeting American College Rheumatology
  • Chair of Annual American College of Physicians Annual Meeting


  • Internal Medicine
  • Internal Medicine - Rheumatology

Specialty Interests

Vasculitis, gout, systemic lupus, myositis, multi-system involvement in autoimmune disease

Awards & Honors

  • Cleveland Best Doctors list for many years


  • Association Program Director of Internal Medicine
  • Fellow American College of Rheumatology
  • Fellow American College of Physicians
Research & Publications

Research & Publications

See publications for Brian Mandell, MD, PhD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 3/21/2023, Dr. Mandell has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Consulting and/or Speaking. Dr. Mandell receives fees of $5,000 or more per year (or, in rare cases, equity or stock options) as a paid consultant, speaker or as a member of an advisory committee for the following companies:

  • Horizon CME, Inc.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

248 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.9 out of 5
Explains 4.9
Courtesy, Respect & Concern 4.9
Patient Rating of Doctor 4.9

70 Patient Comments

Reviewed on Nov 3, 2023

Dr. Mandell is a gem. Knowledgeable, friendly and thorough.

Reviewed on Nov 2, 2023

Dr. Mandell is an amazing physician. He genuinely cares for his patients. He takes the time and is never rushed. He explains everything so that it is understandable. Absolutely amazing!

Reviewed on Oct 11, 2023

I absolutely love DR Mandell

Reviewed on Oct 11, 2023

Dr. Mandell is very attentive and thorough and takes all the time needed to answer any questions that I have.

Reviewed on Oct 11, 2023

I have already recommended Dr. Mandell to other friends of mine.

Reviewed on Oct 11, 2023

Dr. Brian Mandell always goes above and beyond what is expected. He is courteous,kind and understanding.

Reviewed on Oct 4, 2023

Good experience, I love going to see Dr. Mandell . He really listens to his patients. He comes up with alternatives for my care . He has compassion for his patients

Reviewed on Oct 4, 2023

Dr. Mandell was excellent at listening to me explain my symptoms and providing excellent follow up care.

Reviewed on Sep 21, 2023

Dr Mandell is a great doctor; has been to me for many years. Looks beyond his specialty based on his analysis and refers me to other CC specialists. Amazing!

Reviewed on Sep 20, 2023

Dr. Mandell was the most professional and thorough doctor I've ever had the privilege of being cared by.

Reviewed on Sep 19, 2023

As an old RN I judge Dr. Mandel as an intelligent,kind outstanding physician.

Reviewed on Sep 19, 2023

Awesome amazing Dr and staff travel 4 hrs each way to see Dr Mandell!

Reviewed on Sep 12, 2023

Dr. Mandell is amazing and a wonderful doctor.

Reviewed on Sep 12, 2023

This is one of the best doctors the Clinic has.

Reviewed on Sep 12, 2023

Dr.Brian Mandell and his staff are wonderful!!

Reviewed on Sep 5, 2023

It is of course better to see Dr. Mandell in person but the video appointment still worked out well overall because it saved a trip.

Reviewed on Aug 29, 2023

Dr. Mandell is the best at listening to what the patient is feeling and explaining the go forward plan.

Reviewed on Aug 29, 2023

I am very happy with the care I have received from Dr. Mandell. He listens well and shows great interest in all our interactions. He engenders confidence and a feeling of being properly cared for.

Reviewed on Aug 24, 2023

Dr. Mandell went over and above when treating me.

Reviewed on Aug 23, 2023

Loved Dr. Mandell. With him for almost an hour and a half!

Reviewed on Jul 26, 2023

I recommend dr Mandell highly

Reviewed on Jul 26, 2023

I have had excellent care with Dr Mandell office

Reviewed on Jul 20, 2023

Dr. Mandel is an absolute amazing doctor. The time and patience he gives each of his patients is remarkable. The Cleveland clinic should be grateful to have a doctor on staff is knowledgeable and compassionate is Dr. Mandel.

Reviewed on Jul 18, 2023

I enjoyed an outstanding visit with Dr. Mandell

Reviewed on Jul 11, 2023

Dr Mandell is the best. He is very kind, understanding and patient. He goes out of his way to make sure that you are taken care of.

Reviewed on Jul 5, 2023

Dr. Mandell in my opinion is a very knowledgeable doctor, very caring, and will listen to the patient concerns and give his medical advice to the patient in detail. Excellent.

Reviewed on Jun 28, 2023

Dr. Mandell is the best.

Reviewed on Jun 20, 2023

Because initial possible diagnosis was made by a different doctor at CC, I felt like Dr. Mandell was less attentive to my concerns/issues then I was expecting.

Reviewed on Jun 13, 2023

Dr. Mandell is very personable and listens to my concerns. The adjustments he made to my medicine are working very well.

Reviewed on Jun 8, 2023

Dr. Mandell is a brilliant physician. Kind, easy to talk to and never rushes through visits with his patients. I'm grateful to be a patient of his.

Reviewed on May 31, 2023

The wait time to schedule an appointment with Dr. Mandell wasn't good. I appreciate the ability to be placed on a wait list which shortened my original scheduled appointment by approximately 4 - 6 weeks.

Reviewed on May 18, 2023

I never have a bad experience, Dr Mandell is the best doctor. Compassionate, kind and really listens to his patients

Reviewed on May 10, 2023

Dr. Mandell best of the best !

Reviewed on May 9, 2023

Dr. Brian Mandell was excellent taking time to explain everything and our options for treatment.

Reviewed on Apr 19, 2023

Dr Mandell was one of the best doctors I have ever been treated by. He listened to all of my concerns, was incredibly knowledgeable and thorough, and was very kind. He went out of his way to lessen my anxieties and I appreciate that so much.

Reviewed on Apr 13, 2023

Dr Mandell was one of the most conscientious doctors I have ever seen . He was kind and wanted to get to the source of problem . He never rushed

Reviewed on Apr 13, 2023

I initially did a self referral . The very next day I had an appt scheduled . Dr Mandell has reported all my test to me personally

Reviewed on Mar 30, 2023

Wonderful caring and a great doctor!!

Reviewed on Mar 28, 2023

Dr. Mandell went above and beyond to fit my appointment in. I come from out of state for these treatments and he made it possible to see me, so I would not have to make another trip to Ohio.

Reviewed on Mar 28, 2023

Dr Brian Mandell is the best

Reviewed on Mar 27, 2023

Dr. Mandell is always so pleasant. He is very thorough snd really listens

Reviewed on Mar 27, 2023

Dr Mandel was very thorough in going over lab results and informing me about next steps. He is quick to respond via online portal.

Reviewed on Mar 22, 2023

So pleased with Dr. Mandel. So informative, came home knowing I had seen just the right doctor.

Reviewed on Mar 15, 2023

Dr. Mandell is one of, if not the best, doctor I've had. He is friendly, caring and very knowledgeable. He answers my questions thoroughly and is always responsive to my concerns either in person or online. He's the best!

Reviewed on Mar 15, 2023

He is the most amazing doctor. He always makes me feel like his top priority and that he really cares about my well being. I would definitely recommend him to everyone.

Reviewed on Mar 13, 2023

Have always received highest quality of care from Dr Mandell

Reviewed on Mar 13, 2023

Dr. Mandell expressed sincere concern about my health issues, made me feel heard, was patient in addressing the concerns that both myself and my husband had and went above by addressing additional health concerns without waiting for appt with primary care physician. Due to the concern of this provider, I have made the decision in switching to Cleveland Clinic for all of my needs, even though I was apprehensive about the amount of walking from parking to reach appts, a provider such as he makes it worth it.

Reviewed on Mar 8, 2023

Dr. Mandell is always professional, attentive, sincere...

Reviewed on Mar 2, 2023

Dr. Mandell has a wonderful personality and communicates with care.

Reviewed on Feb 27, 2023

My health improved with the care from parking the car to the staff and doctors visits. I trusted and believed I was was getting the very best care possible. And I did

Reviewed on Feb 27, 2023

I had a very good experience with Dr.Mandel

Reviewed on Feb 23, 2023

The lady who scheduled my appointments for me was the most courteous kindest lady I have met in a very long time for the reasons I was there she took very good interest when the date did not coincide with what I needed she did her best she found me an appointment with a very good doctor

Reviewed on Feb 23, 2023

Dr Mandell answered all my questions with easy to understand language. He was incredibly considerate of my previous Rheumatology team.

Reviewed on Feb 21, 2023

Dr Mandel has been very helpful with my situation.

Reviewed on Feb 20, 2023

Dr. Mandell is aways caring and knowledgeable.

Reviewed on Feb 20, 2023

Dr. Mandel - A1

Reviewed on Feb 14, 2023

Dr. Mandell's assistant scheduled for me.

Reviewed on Feb 14, 2023

5 isn't high enough to rate Dr. Mandell. He is a 10! He practices medicine the good old fashioned way - he takes an excellent history and examines me. He does shared decision making. I really appreciate his skill and knowledge.

Reviewed on Feb 14, 2023

Dr Mandell is caring, professional, and always puts me at ease by answering my question. Best doctor I have!

Reviewed on Feb 8, 2023

Dr. Mandell NEVER makes it seem like he is in a rush, and he listens carefully to all concerns. Thank you!

Reviewed on Feb 2, 2023

Excellent provider

Reviewed on Feb 1, 2023

Dr Mandell always takes the time to address my concerns/questions. We have a good doctor/patient relationship.

Reviewed on Jan 30, 2023

Have NEVER had a doctor spend so much time questioning, recommending and explaining. Amazing!!

Reviewed on Jan 25, 2023

Dr. Mandell was extremely thorough and knowledgeable. He was very kind and spent so much time with me getting a health history and answering questions. I have never had a physician spend so much time and not rush the exam.

Reviewed on Jan 19, 2023

Wonderful and caring Dr.Brian Mandel!!! Excellence all around!!!

Reviewed on Jan 17, 2023

Dr. Mandell is a very caring and knowledgeable doctor.

Reviewed on Jan 16, 2023

Excellent doctor.

Reviewed on Jan 10, 2023

Ive seen over 20 doctors in the past 18 months and Dr. Mandell is the by far the best for too many reasons to list.

Reviewed on Jan 9, 2023

Dr Mandell spent a lot of time with me. He looked at all aspects of my lifestyle and made recommendations.

Reviewed on Dec 14, 2022

Dr Mandell was wonderful. He listened, gave thorough feedback, was genuine and kind, and made me feel heard and confident I received the care I needed.

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