Department Rheumatologic and Immunologic Disease
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English
Surgeon No
Locations Specialties & Treatments

Treatment & Services

  • Administration Of Injectable Medications For Osteoporosis
  • Bone Density Testing
  • General Rheumatology
  • General Rheumatology including Lupus
  • Infusions Of Biologic Agents On Site
  • Joint Aspiration
  • Joint Injections
  • Rheumatology
View all 8 Treatment & Services +

Specialty in Diseases & Conditions

  • Arthritis
  • Benign Hypermobility Joint Syndrome
  • Bursitis
  • Giant Cell Arteritis
  • Gout
  • Granulomatosis with Polyangitis (Wegener’s)
  • Lupus
  • Myositis
  • Polyarteritis Nodosa
  • Polymyositis
  • Rheumatoid Arthritis: How to Treat
  • Scleroderma
  • Sjogren's Syndrome
  • Systemic Lupus
  • Uveitis
  • Vasculitis
View all 16 Specialties +


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About Brian Mandell, MD, PhD

Brian Mandell, MD, PhD, is board-certified in internal medicine and rheumatology. He is Director of Scholarly Activities of the Internal Medicine Residency Program at Cleveland Clinic, and serves on the Clinic's Board of Governors, the Graduate Medical Education Council, Continuing Health Sciences Education Committee, and Education Governing Group.

Dr. Mandell is also Editor-in-Chief, Cleveland Clinic Journal of Medicine.
Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Hospital of the University of Pennsylvania
Philadelphia, PA USA

Residency - Hospital of the University of Pennsylvania
Internal Medicine
Philadelphia, PA USA

Internship - Hospital of the University of Pennsylvania
Internal Medicine
Philadelphia, PA USA

Medical Education - New York University School of Medicine
New York, NY USA

Medical Education - Washington University School of Medicine
St. Louis, MO USA

Undergraduate - Washington University
St. Louis, MO USA

Additional Training

  • Stanford University Clinical Teaching Faculty Development Program

Professional Highlights

  • Editor, Rheumatology and Allergy Sections, The Merck Manual (home and professional editions)
  • Chair of Annual Scientific Meeting American College Rheumatology
  • Chair of Annual American College of Physicians Annual Meeting


  • Internal Medicine
  • Internal Medicine - Rheumatology

Specialty Interests

Vasculitis, gout, systemic lupus, myositis, multi-system involvement in autoimmune disease

Awards & Honors

  • Cleveland Best Doctors list for many years


  • Association Program Director of Internal Medicine
  • Fellow American College of Rheumatology
  • Fellow American College of Physicians
Research & Publications

Research & Publications

See publications for Brian Mandell, MD, PhD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 6/7/2020, Dr. Mandell has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Consulting and/or Speaking. Dr. Mandell receives fees of $5,000 or more per year as a paid consultant, speaker or member of an advisory committee for the following companies:

  • Genentech, Inc

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

169 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.9 out of 5
Explains 4.9
Courtesy, Respect & Concern 4.9
Patient Rating of Doctor 4.9

29 Patient Comments

Reviewed on Sep 14, 2020

Excellent doctor who is always available whenever needed. Very compassionate and treats me like part of his family...........Could not ask for a better doctor

Reviewed on Sep 1, 2020

I've been a patient of Dr Mandel's for a number of years and find him to be compassionate kind and caring as well as extremely professional. I feel he is genuinely involved in the welfare of each of his patients individually. I really appreciate his open, honest and laid-back approach to some very serious health problems of mine. he without any doubt Is the best doctor I have ever experienced in my 73 years.

Reviewed on Aug 19, 2020

Dr. Mandell is the best doctor I have every had.

Reviewed on Aug 19, 2020

Dr Mandel is a caring professional, I am grateful to have him as my doctor.

Reviewed on Aug 5, 2020

I have seen many different doctors for my RA and Dr. Mandell was by far my favorite. He made me feel hopeful that it could be controlled and that I might be able to finally live as much of a normal life that I could . I am so extremely thankful that I saw him and look forward to him being my doctor through this disease

Reviewed on Jul 13, 2020

It is so very hard to find a doctor as knowledgeable as dr Mandell and one who cares about your wellbeing as well he just simply the best there is

Reviewed on Jul 7, 2020

DR Mandel is the best.

Reviewed on Jun 18, 2020

waited quite a while for the appt , but I understand that Dr Mandel is very busy.

Reviewed on Jun 18, 2020

My doctor's office had to send the referral over three times and make a phone call before someone scheduled an appointment.

Reviewed on Jun 15, 2020

Care was primarily by Dr, B Mandell.....what an amazing an giving MD. He should be named MD of the century.

Reviewed on Jun 11, 2020

Dr Mandell is wonderful

Reviewed on Jun 11, 2020

Dr.Mandel is a great doctor

Reviewed on May 19, 2020

dr. mandel is particularly easy to talk with. never feel rushed. always feel like you're his only patient.

Reviewed on May 13, 2020

Dr. Mandell was very thorough and took the time to discuss all of my symptoms. He has a wonderful "bedside manner."

Reviewed on May 12, 2020

dR. Mandell is always concerned about my well being and stays very informed on my progress. He is the best.

Reviewed on Mar 23, 2020

best dr i have ever had

Reviewed on Mar 19, 2020

He is truly awesome! I travel 5hrs to see him. He is always available to me when I need him. I work in the Healthcare industry and our physicians are not like him. He is truly concerned for the health and welfare of his patients. That's why I travel 5 hrs just to see him.

Reviewed on Jan 29, 2020

Dr Mandel is a very caring doctor who always replies to any questions I may have promptly. I am lucky to have him as my doctor...

Reviewed on Jan 16, 2020

Best Doctor that I have seen in 40 years. Need more Doctors like Mandell.

Reviewed on Jan 15, 2020

I have recommended Dr. Mandell to several friends and family members

Reviewed on Jan 13, 2020

Dr Mandell's is an ELITE physician in his specialty and he provided an ELITE initial experience as a care provider and the plan was thought out very well and needs to be reviewed as time passes throughout the next 6 months.

Reviewed on Dec 10, 2019

Dr Mandell Is an absolutely outstanding and caring physician. He is absolutely the best doctor whom I have ever seen.

Reviewed on Dec 5, 2019

I requested a visit with DrMandell because of pain and other issues.He had me come see him withina day.He has always been there when needed.He has been my Dr for 26 yrs.

Reviewed on Dec 5, 2019

Dr Mandell has been my provider for 26 years now. I am vey comfortable and confident in his care.

Reviewed on Dec 4, 2019

Dr. Mandell seemed very competent and concerned about my problem. He listened and also offered recommendations for treatment.

Reviewed on Dec 3, 2019

I am certain that the degree to which my RA is maintained is due to Dr. Mandell's care, expertise, concern, and including me in all decisions and discussions!

Reviewed on Dec 3, 2019

Dr. Mandell was very helpful and clearly explained the parameters and options for treatment of my condition.

Reviewed on Nov 19, 2019

Dr. Mandell is fantastic!!! Soooo glad we found him !!!!

Reviewed on Nov 14, 2019

Of all the Cleveland clinic doctors I see, Dr Mandell is the best.

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