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Department Rheumatologic and Immunologic Disease
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English
Surgeon No
Locations Specialties & Treatments

Treatment & Services

  • Administration Of Injectable Medications For Osteoporosis
  • Adult Rheumatology
  • Arthritic Knee Conditions
  • Bone Density Testing
  • Clinical Trials
  • Cortisone injections
  • Diagnosis of Osteoporosis
  • Dual Energy X-ray Absorptiometry (DXA)
  • General Rheumatology
  • General Rheumatology including Lupus
  • Hyaluronic acid (HA)
  • Hyaluronic acid injections
  • Immunoglobulin Infusion
  • Immunotherapy
  • Infusion Therapy
  • Infusions Of Biologic Agents On Site
  • Joint Aspiration
  • Joint Injections
  • Joint Preservation Center
  • Medical Management of Early Osteoarthritis
  • Medication Management
  • Musculoskeletal Evaluation
  • Musculoskeletal Medicine
  • Musculoskeletal Treatment For Joint Pain
  • Rheumatology
  • Steroid Injections
  • Therapeutic Injections
  • Ultrasound-guided Procedures
  • Viscosupplementation
  • Viscosupplementation Injections
View all 30 Treatment & Services +

Specialty in Diseases & Conditions

  • EGPA (Eosinophilic granulomatosis with Polyangiitis)
  • AIDS & HIV
  • Ankylosing Spondylitis
  • Antiphospholipid Syndrome
  • Arthritic Knee Problems
  • Arthritis
  • Arthritis of the Foot and Ankle
  • Arthritis Of The Hip
  • Arthritis Of The Knee
  • Arthritis of the Thumb Base
  • Arthritis of the Wrist & Hand
  • Autoimmune Disease
  • Autoinflammatory Syndromes
  • Behcet's Disease
  • Benign Hypermobility Joint Syndrome
  • Buerger's Disease
  • Bursitis
  • Calcification Tendinitis
  • Calcinosis
  • Central Nervous System Vasculitis
  • Chondrocalcinosis (Pseudo Gout)
  • Churg-Strauss Syndrome
  • Connective Tissue Diseases
  • Connective Tissue Disorders
  • Cryoglobulinemia
  • Dermatomyositis
  • Elbow Arthritis
  • Familial Mediterranean Fever
  • Familial Mediterranean Fever (FMF) Syndrome
  • Foot & Ankle Arthritis
  • Giant Cell Arteritis
  • Gout
  • Gout Arthritis
  • Granulomatosis with Polyangitis (Wegener’s)
  • Hand and Wrist Arthritis
  • Hand Pain
  • Hand Problems
  • Henoch Schonlein Purpura
  • Hip Arthritis
  • Hip Disorders
  • Hip Pain
  • Immunodeficiency
  • Immunosuppression
  • Inflammatory Arthritis
  • Iritis
  • Joint Pain
  • Knee Arthritis
  • Knee Joint Disorders
  • Knee Pain
  • Lupus
  • Lupus Anticoagulant
  • Lupus Nephritis
  • Metabolic Bone Disease
  • Metabolic Diseases
  • Microscopic Polyangiitis (MPA)
  • Musculoskeletal Disorders
  • Musculoskeletal Impairments
  • Musculoskeletal Pain
  • Myositis
  • Osteoarthritis
  • Osteoarthritis Of The Hips And Knees In The Elderly
  • Painful Joints
  • Palindromic Rheumatism
  • Panuveitis
  • Polumyalgia Rheumatica
  • Polyarteritis Nodosa
  • Polymyositis
  • Pseudogout
  • Psoriatic Arthritis
  • Radiculopathy
  • Raynaud's Phenomenon
  • Reactive Arthritis
  • Relapsing Polychondritis
  • Retroperitoneal Fibrosis
  • Rheumatoid Arthritis
  • Rheumatoid Arthritis and Heart Disease
  • Rheumatoid Arthritis: How to Treat
  • Sacroilitis
  • Sarcoidosis
  • Scleritis
  • Scleroderma
  • Shoulder Arthritis
  • Shoulder Pain
  • Sjogren's Syndrome
  • Spondylitis
  • Spondyloarthopathy
  • Spondyloarthropathies
  • Spondylosis
  • Systemic Autoimmune Diseases
  • Systemic Lupus
  • Systemic Lupus Erythematosus
  • Tendinosis
  • Tendonitis
  • Tenosynovitis
  • Trigger Finger
  • Uveitis
  • Vasculitis
View all 97 Specialties +


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About Brian Mandell, MD, PhD

Brian Mandell, MD, PhD, is board-certified in internal medicine and rheumatology. He is Director of Scholarly Activities of the Internal Medicine Residency Program at Cleveland Clinic, and serves on the Clinic's Board of Governors, the Graduate Medical Education Council, Continuing Health Sciences Education Committee, and Education Governing Group.

Dr. Mandell is also Editor-in-Chief, Cleveland Clinic Journal of Medicine.
Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Hospital of the University of Pennsylvania
Philadelphia, PA USA

Residency - Hospital of the University of Pennsylvania
Internal Medicine
Philadelphia, PA USA

Internship - Hospital of the University of Pennsylvania
Internal Medicine
Philadelphia, PA USA

Medical Education - New York University School of Medicine
New York, NY USA

Medical Education - Washington University School of Medicine
St. Louis, MO USA

Undergraduate - Washington University
St. Louis, MO USA

Additional Training

  • Stanford University Clinical Teaching Faculty Development Program

Professional Highlights

  • Editor, Rheumatology and Allergy Sections, The Merck Manual (home and professional editions)
  • Chair of Annual Scientific Meeting American College Rheumatology
  • Chair of Annual American College of Physicians Annual Meeting


  • Internal Medicine
  • Internal Medicine - Rheumatology

Specialty Interests

Vasculitis, gout, systemic lupus, myositis, multi-system involvement in autoimmune disease

Awards & Honors

  • Cleveland Best Doctors list for many years


  • Association Program Director of Internal Medicine
  • Fellow American College of Rheumatology
  • Fellow American College of Physicians
Research & Publications

Research & Publications

See publications for Brian Mandell, MD, PhD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 4/13/2022, Dr. Mandell has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Consulting and/or Speaking. Dr. Mandell receives fees of $5,000 or more per year as a paid consultant, speaker or member of an advisory committee for the following companies:

  • Horizon CME, Inc.
  • Chemocentryx

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

161 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.9 out of 5
Explains 4.9
Courtesy, Respect & Concern 4.9
Patient Rating of Doctor 4.9

67 Patient Comments

Reviewed on May 25, 2022

Dr. Mandell was truly a breath of hope & confidence in my health saga of over a year. He immediately put my fears aside and explained what was happening with my body. It was a gift to meet him and for him to hear my concerns.

Reviewed on May 23, 2022

Dr. Mandell was very compassionate. He took his time and really reviewed my case before my appt. Although he was not able to give me answers, he was extremely helpful in connecting me to the doctor I should see. I was very impressed with him!

Reviewed on May 17, 2022

I have been a patient of Dr. Mandell s for over 20 years. He is the best!!

Reviewed on May 11, 2022

I wish my primary physician was as great as Dr. Mandala!

Reviewed on May 10, 2022

Dr. Mandell is a wonderful person. Knowledgeable and caring and thorough. Glad he's mt doctor.

Reviewed on May 9, 2022

Dr. Mandela was great! Very respectful, and funnny.

Reviewed on Apr 26, 2022

Dr Mandell returned my call and set up the video appointment very promptly.

Reviewed on Apr 26, 2022

Dr Mandell was exceptional at answering questions and providing all information regarding my condition. He clearly states the plan he had for my treatment and covers all bases.

Reviewed on Apr 26, 2022

Dr Mandell and his staff are exceptional.

Reviewed on Apr 20, 2022

Dr Mandell has always been very responsive to patient needs. As I a from out of state, he has been very accommodating to schedule when I can be there and goes to extra effort to ensure I get top quality care during the time I am available.

Reviewed on Apr 20, 2022

Dr Mandell has been the most reliable and trust worthy doctor I have had during my diagnosis and treatments. I have been blessed and lucky to have found such an incredible and knowledgable medical professional.

Reviewed on Apr 13, 2022

I've rated how well the staff worked together to care for me as good. But, I have no idea how well they work as providers' visits with me are independent, they are one after another.

Reviewed on Mar 29, 2022

Dr Brian Mandell is the best

Reviewed on Mar 29, 2022

*Dr. Mandell is the most caring dr. we have ever had. I would recommend her to everyone.

Reviewed on Mar 9, 2022

Dr. Mandell is wonderful. He has a great doctor patient relationship. He is willing to answer questions and will respond quickly to email inquiries through the portal.

Reviewed on Mar 7, 2022

Dr Brian Mandell is the best, been with him more than 20 yrs. Have referred many fiends.

Reviewed on Mar 1, 2022

It was a very good visit with Dr. Mandell. Listened and took his time with me. Felt very comfortable that he will find out what is going on.

Reviewed on Feb 15, 2022

EXCELLENT, this Doctor LISTENED too me

Reviewed on Feb 8, 2022

In dealing with dr.mandell it has always been wonderful he truly cares and it shows in the way his team response to you. They are always willing to go the extra mile to show you that they care about you and try to help because of dealing with his team Its a pleasure to deal with CCF

Reviewed on Feb 8, 2022

I can't not say enough about Dr. Mandell, when I first came to him I was in pain both physically and mentally. I had no hope of ever being rid of this burden I carried. But through the years he has worked wonders , if he could not fixed the problems he knew Dr's that would. I never invision that my life could take such a turn. But Thanks to his Knowledge , his Ability, and to Care about you as a person has made the difference in my life.

Reviewed on Jan 24, 2022

Excellent doctor and staff

Reviewed on Jan 20, 2022

Dr Mandela is an excellent clinician and has a very caring bedside manner

Reviewed on Jan 19, 2022

This doctor is excellent. One of the best I've ever had.

Reviewed on Jan 18, 2022

Great and caring physician

Reviewed on Jan 12, 2022

Dr. Mandel took all the time necessary to tease out the issues that were troubling me. Never did he seem rushed or impatient with me. He explained his thoughts thoroughly and without jargon.

Reviewed on Jan 5, 2022

Dr Mandell is the best

Reviewed on Dec 30, 2021

Very thorough exam. Necessary tests were done the same day. Very kind personable doctor.

Reviewed on Dec 10, 2021

Excellent visit with a caring and thorough provider

Reviewed on Nov 24, 2021

Dr. Mandela was very knowledgeable, thorough and personable.

Reviewed on Nov 24, 2021

Dr. Mandell was wonderful, actually the best doctor I've seen in a long time.

Reviewed on Nov 18, 2021

Dr Mandela listened to my concerns and was very patient

Reviewed on Nov 16, 2021

Dr. Mandell was exceptional. He had a great send if humor to relax me and had the best bedside manner of any do Tor I have ever gone to . He was caring thorough and professional and explained everything thoroughly and answered all my questions and addressed all my concerns.

Reviewed on Nov 11, 2021

Great Doctor!!!

Reviewed on Nov 3, 2021

Dr. Mandel always takes the time I need to understand my issues.

Reviewed on Oct 28, 2021

Once again, the care provided by Dr. Mandell was excellent. I feel truly lucky that he provides care for me.

Reviewed on Oct 28, 2021

Dr. Mandell has always been available when I have concerns about my health problems and spends time ro explain what needs to be done. I am thankful I have him for my RA and other related problems.

Reviewed on Oct 27, 2021

Dr. Brian Mandell is an excellent Physician and a very likable man.

Reviewed on Oct 21, 2021

Dr. Mandell has superb provider/patient engagement. It is to be hoped that new physicians follow his style.

Reviewed on Oct 20, 2021

Doctor was awesome. Very pleased with him

Reviewed on Oct 20, 2021

Dr was very personable and made me feel at ease.

Reviewed on Oct 19, 2021

Very happy with this Dr. He was friendly and made me feel better. Very thorough exam.

Reviewed on Oct 18, 2021

Dr Mandell has always been a very honest and caring doctor.

Reviewed on Oct 5, 2021

Dr Brian Mandell is an exceptional doctor that provided an accurate diagnosis and treatment.

Reviewed on Oct 5, 2021

I have recommended Dr Mandell to several people.

Reviewed on Sep 29, 2021

Dr. Mandell is a wonderful doctor - very competent, knowledgeable, and caring.

Reviewed on Sep 23, 2021

There are not enough nice things I can say about Dr Mandel. He is a bonafide treasure!!!

Reviewed on Sep 23, 2021

Dr. Mandell has ALWAYS gone above and beyond the normal call of duty. He is exceptional.

Reviewed on Sep 22, 2021

One of my favorite doctors, very kind, he cares, he knows me well. Responds to my messages

Reviewed on Sep 21, 2021

Dr. Mandell is an excellent physician who LISTENS well, takes a genuine interest in understanding my feedback and any concerns. He doesn't belittle my insight, and is cautious to ensure all aspects of my RA and total health are being addressed

Reviewed on Sep 21, 2021

Dr went above and beyond expected in responding to my questions and concerns.

Reviewed on Sep 8, 2021

Dr Mandell is caring, provided clear information, I couldn't have asked for a better doctor!

Reviewed on Aug 30, 2021

So happy to have dr Mandelll as my doctor

Reviewed on Aug 30, 2021

Dr. Mandell is always attentive & responds to concerns in easy to understand lay terms. In my opinion he's the best! I come from Chicago to seek his help with my health problems & he always finds the best resolutions. Any time I have a question & I e-mail him he answers promptly.

Reviewed on Aug 19, 2021

Dr Mandell is very respectful, compassionate and shows genuine concern for his patients. He has been a godsend for me after my diagnosis

Reviewed on Aug 19, 2021

Love Dr. Mandell he always answers all my questions and goes above and beyond. Have recommended to many people and those who do go always thanks me for recommending him.

Reviewed on Aug 10, 2021

Awesome doctor!

Reviewed on Jul 27, 2021

I have recommended Dr. Mandell to many family and friends. He is an outstanding physician.

Reviewed on Jul 21, 2021

I have recommended Dr. Mandel to several people

Reviewed on Jul 15, 2021

All good with the doctor and his support team.

Reviewed on Jul 13, 2021

*Dr. Mandell is the best - I've been his patient for many years & we drive a distance to see him!

Reviewed on Jun 29, 2021

I can't say enough good about Dr. Brian Mandell. He is very thorough with exams and provides information that is easily understood by the lay person.

Reviewed on Jun 21, 2021

dr. mandell was excellent. he took the time to listen to my health issues, explained them to me in a prefessional mattere , cleared my doubts and possible treatments. i was for ever gratefull because he cleared my doubts and i felt more at peace

Reviewed on Jun 17, 2021

my entire process was great! Those on the phone were professional and very courteous! Iwas looking for the earliest appointmentand due to a cancellation I got a same day appointment. I was really thankful that Dr BrianMandel was able to answer all my questions and took the time to explain what my options would be. very thankful

Reviewed on Jun 17, 2021

Very pleased that the Dr took the time toaddress all my concerns.!! And to listen to what I asked and very helpful!!

Reviewed on Jun 16, 2021

awesome doctor, takes his time and answers all questions. makes you feel comfortable

Reviewed on Jun 15, 2021

Dr Mandel very attentive, very good experience

Reviewed on Jun 14, 2021

not only I respect Dr Mandell professionalism , I love Dr Mandell bed side manners. He always take time to listen to my concerns and ask / care genuinely about my family ( my children in particular).

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