Department Allergy and Clinical Immunology
Primary Location Cleveland Clinic Main Campus
Type of Doctor Both Adults and Children & Adolescents
Languages English
Surgeon No
Locations Specialties & Treatments

Treatment & Services

  • Allergy Immunotherapy
  • Allergy Skin Tests
  • Allergy Tests
  • Anti-ige Injection Therapy
  • Aspirin Challenge
  • Blood Test (rast) For Allergies
  • Clinical Trials
  • Diagnosing Asthma
  • Diagnostic Skin Testing For Food, Inhalant, And Drug Allergy
  • Drug Allergy Desensitization Therapy
  • Drug Challenge and Desensitization
  • Evidence-based Medicine
  • Exhaled Breath Analysis
  • Food Challenge Test
  • Immunodeficiency Evaluation
  • Immunoglobulin Infusion
  • Immunotherapy
  • Intravenous Immunoglobulin Therapy
  • Peak Flow Meter
  • Penicillin Allergy Testing
  • Pulmonary Function Testing
  • Screening and Testing
  • Treating Asthma With Bronchodilators
View all 23 Treatment & Services +

Specialty in Diseases & Conditions

  • Airborne Allergens
  • Allergic Conjunctivitis
  • Allergic Disorders
  • Allergies
  • Allergy Skin Testing
  • Anaphylaxis
  • Asthma
  • Bee Stings
  • Eczema
  • Egg Allergy
  • Environmental Allergies
  • Eosinophilia
  • Fish Allergy
  • Food Allergies
  • Hay Fever
  • Hives (Urticaria)
  • Insect Sting Allergies
  • Latex Allergy
  • Medication Allergies
  • Milk Allergies
  • Milk Allergy
  • Nut Allergy
  • Ocular Allergies
  • Seasonal Allergies
  • Shellfish Allergy
  • Soy Allergy
  • Urticaria
  • Wheat Allergy
View all 28 Specialties +


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About Fred Hsieh, MD

Fred Hsieh, MD, is a Staff Physician in the Respiratory Institute at Cleveland Clinic. He is board-certified in internal medicine and allergy and clinical immunology.

He has a specialty practice limited to allergy and clinical immunology and sees adult and pediatric patients. 

Dr. Hsieh currently has conducted research funded by the National Institutes of Health and was previously funded by the Howard Hughes Medical Institute.  His work has been recognized by the American Academy of Allergy, Asthma, and Immunology Respiratory Diseases Research Award and the Glaxo-Wellcome Allergy Fellowship Award.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Brigham & Women's Hospital
Allergy and Immunology
Boston, MA USA

Residency - Johns Hopkins Hospital
Internal Medicine
Baltimore, MD USA

Medical Education - Brown University School of Medicine
Providence, RI USA

Undergraduate - Brown University
Providence, RI USA

Additional Training

Professional Highlights

  • Fellow, American College of Allergy, Asthma, and Immunology
  • Fellow, American Academy of Allergy, Asthma, and Immunology
  • former Associate Editor, Annals of Allergy, Asthma, and Immunology


  • Internal Medicine - Allergy & Immunology
  • Allergy and Immunology
  • Internal Medicine

Specialty Interests

Allergy, asthma, rhinitis, food allergy, insect sting allergy, urticaria and angioedema

Awards & Honors

  • Sigma Xi
  • Howard Hughes Medical Institute Research Training Fellowship
  • American Academy of Allergy, Asthma, and Immunology Respiratory Diseases
  • Research Award, Glaxo-Wellcome Allergy Fellowship Award 
  • Allergy and Immunology Teacher of the Year
  • Best Doctors, Allergy and Immunology, Adult, 2009-present


    Innovations & Patents


    • American Academy of Allergy, Asthma, and Immunology
    • American College of Allergy, Asthma, and Immunology
    • Massachusetts Medical Society
    • Cleveland Allergy Society
    • American Thoracic Society
    Research & Publications

    Research & Publications

    See publications for Fred Hsieh, MD.

    (Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

    Industry Relationships

    Industry Relationships

    Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

    To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

    As of 4/1/2019, Dr. Hsieh has reported no financial relationship with industry that is applicable to this listing. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

    Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

    * Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

    Patient Satisfaction Reviews

    101 Patient Satisfaction Reviews

    The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

    Responses are measured on a scale of 1 to 5 with 5 being the best score.

    The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

    Overall Star Ratings
    4.5 out of 5
    Explains 4.5
    Listens 4.3
    Courtesy, Respect & Concern 4.6
    Knows Medical History 4.1
    Time Spent with Patient 4.5
    Patient Rating of Doctor 4.5

    16 Patient Comments

    Reviewed on Jun 27, 2019

    pretty good liked doctor lot .explained very well.

    Reviewed on Jun 10, 2019

    very impressed with dr , very good bed side manners and concered !

    Reviewed on May 17, 2019

    Dr. Hsieh has always treated me with respect & care. He is one of the 1st Allergy Care Providers I've ever had that allows me to be part of the discussion. He ALWAYS takes time to answer my questions & is never condescending! I look fwd to seeing him again!

    Reviewed on May 17, 2019

    Doctor is awesome

    Reviewed on May 14, 2019

    Dr. Hsieh is by far my favorite doctor I have ever had. He took my mental illness into account and took it at face value. I have never had a doctor do that before.

    Reviewed on May 7, 2019

    Dr. Hsieh was excellent. He explained everything very thoroughly and was very friendly.

    Reviewed on May 3, 2019

    Dr Hseih did an excellent job of listening to my concerns and struck the right balance educating me about my situation and providing me with instruction.

    Reviewed on Apr 1, 2019

    Excellent experience with everyone at Cleveland Clinic especially Dr. Hsieh.

    Reviewed on Jan 21, 2019

    The doctor's knowledge,I am certain was good, however I would suggest a little more compassion or something. Also he was sort of slouched in this chair which I found rather unsual. Bedside manner needs some work.

    Reviewed on Oct 26, 2018

    I have to say Dr Fred Hseish is one of the best doctors I have seen. initially I remember with my issue getting worst and he had so much patience when I was kinda rude . but his assurance made me feel better and better . I have to name Nurse Joyce she is one of the best you have . she is amazing . the front office or tech Sarah is another one good person I have to say . nurse Denise is also good . but since Nurse Joyce is the one who I see mostly . I am getting better and better .

    Reviewed on Sep 17, 2018

    Hate the drive up to clinic. Provider had more information this time for me. Usually not much info available on my problem. He was very helpful explaining to husband.

    Reviewed on Sep 17, 2018

    Dr Hseigh says he is well-informed and ready to diagnose and treat mast cell activation disorder yet his knowledge was sorely lacking, limited to only one groups opinion of how to diagnose it and showed no interest or willingness to understand symptoms and past treatments nor that of many other with MCAS. He also did not take any interest into other immune issues already documented.

    Reviewed on Sep 17, 2018

    The dr failed to provide any treatment or even see me when I had a severe allergic response starting after appt but still in office. Staff tried to get his response so I rate poorly because of the dr.s response.

    Reviewed on Sep 17, 2018

    the phlebotomist was amazing. she helped make up for the lack of communication and understanding the doctor had.

    Reviewed on Aug 1, 2018

    The dr. was very thorough, pleasant and concerned. He will be part of my health care team.

    Reviewed on Jul 5, 2018

    while i was incorrectly referred to this doctor by my primary care physician he was patient and listened anyway trying to offer me any options or answers even though this clearly was not his problem. I appreciated his patience and understanding despite all of this when most doctors would not have shown me the same kindness. If I do ever need follow up with my allergies I will definitely go back to him.

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