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Department Allergy and Clinical Immunology
Primary Location Cleveland Clinic Main Campus
Type of Doctor Both Adults and Children & Adolescents
Languages English
Surgeon No
Locations Specialties & Treatments

Treatment & Services

  • Allergy Immunotherapy
  • Allergy Skin Tests
  • Allergy Tests
  • Anti-IgE Injection Therapy
  • Aspirin Challenge
  • Blood Test (RAST) for Allergies
  • Clinical Trials
  • Diagnosing Asthma
  • Diagnostic Skin Testing for Food, Inhalant, and Drug Allergy
  • Drug Allergy Desensitization Therapy
  • Drug Challenge
  • Drug Desensitization
  • Evidence-based Medicine
  • Exhaled Breath Analysis
  • Food Challenge Test
  • Immunoglobulin Infusion
  • Immunotherapy
  • Intravenous Immunoglobulin Therapy
  • Penicillin Allergy Testing
  • Treating Asthma with Bronchodilators
View all 20 Treatment & Services +

Specialty in Diseases & Conditions

  • Airborne Allergens
  • Allergic Conjunctivitis
  • Allergic Disorders
  • Allergies
  • Anaphylaxis
  • Angioedema
  • Asthma
  • Bee Stings
  • Drug Allergy
  • Egg Allergy
  • Environmental Allergies
  • Fish Allergy
  • Food Allergies
  • Hay Fever
  • Hives (Urticaria)
  • Insect Sting Allergies
  • Latex Allergy
  • Medication Allergies
  • Milk Allergy
  • Nut Allergy
  • Ocular Allergies
  • Penicillin Allergy
  • Seasonal Allergies
  • Shellfish Allergy
  • Soy Allergy
  • Urticaria
  • Wheat Allergy
View all 27 Specialties +


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About Fred Hsieh, MD

Fred Hsieh, MD, is a Staff Physician in the Respiratory Institute at Cleveland Clinic. He is board-certified in Internal Medicine and Allergy and Clinical Immunology.

He has a specialty practice limited to allergy and clinical immunology and sees adult and pediatric patients. 

Dr. Hsieh has previously conducted research funded by the National Institutes of Health and by the Howard Hughes Medical Institute.  His work has been recognized by the American Academy of Allergy, Asthma, and Immunology Respiratory Diseases Research Award and the Glaxo-Wellcome Allergy Fellowship Award.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Brigham & Women's Hospital
Allergy and Immunology
Boston, MA

Residency - Johns Hopkins Hospital
Internal Medicine
Baltimore, MD

Medical Education - Brown University School of Medicine
Providence, RI

Undergraduate - Brown University
Providence, RI

Additional Training

Professional Highlights

  • Program Director, Allergy and Immunology Fellowship Training Program
  • Vice-Chair, Allergy and Immunology
  • Fellow, American College of Allergy, Asthma, and Immunology
  • Fellow, American Academy of Allergy, Asthma, and Immunology
  • past Associate Editor and Editorial Board Member, Annals of Allergy, Asthma, and Immunology
  • ad hoc reviewer: American Journal of Physiology: Lung Cellular and Molecular Physiology; Respiratory Research; Cleveland Clinic Journal of Medicine; American Journal of Respiratory and Critical Care Medicine; Journal of Pediatrics; Journal of Experimental Medicine; Proceedings of the National Academy of Sciences USA; Journal of Allergy and Clinical Immunology; American Journal of Respiratory Cell and Molecular Biology; Journal of Immunology; Allergy; Journal of Bronchology; Journal of Vascular Research
  • ad hoc grant reviewer: University Grants Committee, Research Grants Council of Hong Kong; American Institute of Biological Sciences-FAMRI; National Heart Lung and Blood Institute, National Institutes of Health; Clinical and Translational Science Collaborative-Clinical and Translational Science Award Program, Case Western Reserve University; Leukemia and Lymphoma Research UK-Northern Ireland; Asthma UK.


  • Allergy and Immunology
  • Internal Medicine

Specialty Interests

Allergy, asthma, rhinitis, food allergy, insect sting allergy, urticaria and angioedema

Awards & Honors

  • Sigma Xi
  • Howard Hughes Medical Institute Research Training Fellowship
  • American Academy of Allergy, Asthma, and Immunology Respiratory Diseases
  • Research Award, Glaxo-Wellcome Allergy Fellowship Award 
  • Allergy and Immunology Teacher of the Year
  • Best Doctors, Allergy and Immunology, Adult, 2009-present


    Innovations & Patents


    • American Academy of Allergy, Asthma, and Immunology
    • American College of Allergy, Asthma, and Immunology
    • Massachusetts Medical Society
    • Cleveland Allergy Society
    • American Thoracic Society
    Research & Publications

    Research & Publications

    See publications for Fred Hsieh, MD.

    (Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

    Industry Relationships

    Industry Relationships

    Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

    To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

    As of 6/26/2024, Dr. Hsieh has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

    Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

    * Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

    Patient Satisfaction Reviews

    84 Patient Satisfaction Reviews

    The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

    Responses are measured on a scale of 1 to 5 with 5 being the best score.

    The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

    Overall Star Ratings
    4.6 out of 5
    Explains 4.7
    Courtesy, Respect & Concern 4.6
    Patient Rating of Doctor 4.5

    14 Patient Comments

    Reviewed on Jun 3, 2024

    I love my doctor ,he is answering all my questions and can easily ask my concerns

    Reviewed on May 16, 2024

    Dr was very attentive, kind and informative

    Reviewed on May 9, 2024

    I was very grateful to see a physician

    Reviewed on Apr 15, 2024

    All doctors and others were very concerned and interested in solving my problem.

    Reviewed on Jan 18, 2024

    Dr. Hsieh is excellent. He's very caring. I have multiple allergies and he's very determined to give me relief from my chronic itching and hives. He promptly updates my medical record with new info from my latest visit.

    Reviewed on Jan 11, 2024

    Dr. Hsieh is an excellent physician. Appointments are scheduled almost 60 days out.

    Reviewed on Dec 15, 2023

    Absolutely would recommend Dr. Hsieh

    Reviewed on Nov 9, 2023

    Provider seemed very disinterested in our concerns and seemed to downplay why we were there. I got zero out of the visits and felt we waisted our time. We drove an hour to see the provider and left feeling deflated and unheard

    Reviewed on Oct 20, 2023

    As a patient, I feel I can trust Dr. Fred Hsieh to handle my concerns. He is an excellent physician.

    Reviewed on Oct 5, 2023

    Great personal treatment. No wait when I arrived at Dr. Hsieh's office. Very rare these days!

    Reviewed on Oct 5, 2023

    I will highly recommend Dr. Hsieh to any family members or friends. He covered all bases!!

    Reviewed on Sep 25, 2023

    The doctor is very much a people person it was very comfortable talking with him

    Reviewed on Sep 25, 2023

    Couldn't have asked for a better doctor that day

    Reviewed on Sep 22, 2023

    Dr. Hsieh is competent compassionate and thorough. Couldn't ask for any better

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