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Department Subspecialty Care for Women’s Health
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English
Surgeon No
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus


Additional Locations

Specialties & Treatments

Treatment & Services

  • Bioidentical Hormone Therapy
  • Bone Density Testing
  • Breast Cancer Risk Assessment
  • Cervical Polypectomy
  • Endometrial Biopsy
  • Interdisciplinary Women's Health
  • IV Reclast Infusion For Postmenopausal Osteoporosis
  • Menopausal Risk Assessment
  • Specialty Women's Health
  • Vertebral Fracture Assessment
  • Women's Health
View all 11 Treatment & Services +

Specialty in Diseases & Conditions

  • Menopause
  • Osteopenia
  • Osteoporosis
  • Perimenopause Symptoms
  • Sexual Dysfunction
  • Sexual Hormone disorders
  • Vaginal Atrophy
View all 7 Specialties +


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About Holly L. Thacker, MD

Holly L. Thacker MD, FACP, director of the Cleveland Clinic Center for Specialized Women’s Health and Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University. She published her second women’s health book “Cleveland Clinic Guide to Menopause.”  Dr. Thacker is the Executive Director of national Speaking of Women's Health and directs the digital platform and directs CustomFit Physicals for women.

She was honored by the American Medical Women’s Association (AMWA) and the Journal of Women’s Health with the "Lila Wallis Women’s Health Award" in recognition of Dr. Thacker’s lifetime achievements, accomplishments, motivation, mentorship, energy and enthusiasm for women’s health, education, and research during the AMWA annual meeting and Women’s Health 2009: The 17th Annual Congress, in Williamsburg, VA.

In the Center for Specialized Women’s Health, we pursue leading edge and interdisciplinary therapies for women with a focus on menopausal and hormone risk assessment and therapies. We have started CustomFit Physicals for women to provide a uniquely personalized healthcare service that combines convenience and comprehensiveness in a one day visit with the service of a nurse navigator.  In addition, there are several new FDA approved pelvic floor stimulators that are available for women with urine leakage and pelvic muscle weakness as well as fecal incontinence and mild degrees of pelvic organ prolapse. These new pelvic floor stimulation devices are custom-fit and use stimulation to strengthen pelvic floor muscles and inhibit overactive bladder muscles while giving visual biofeedback and audible guidance. Precise adjustments can be made to ensure effective muscle training. Some women, who have only stress urinary leakage, and/or are 6 weeks post partum from vaginal delivery, may need simpler devices and all therapies can be done in the comfort and privacy of ones home. These devices can compliment, or in many cases be used instead of surgery or medications.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Residency - Cleveland Clinic
Internal Medicine
Cleveland, OH USA

Internship - Cleveland Clinic
Medical Internship
Cleveland, OH USA

Medical Education - University of Missouri-Kansas City School of Medicine
Kansas City, MO USA

Undergraduate - University of Missouri-Kansas City School of Medicine
Kansas City, MO USA

Professional Highlights

  • Author of the book, The Cleveland Clinic Guide to Menopause, a Cleveland Clinic Guide, © 2009
  • Author of the book, Women's Health: Your Body, Your Hormones, Your Choices, a Cleveland Clinic Guide, © 2007
  • Founder and Director of Women's Health Fellowship


  • Internal Medicine

Specialty Interests

Breast cancer risk assessment, hormone therapy, menopause and related medical problems, menstrual disorders and interdisciplinary women's health, osteoporosis, menopause, women's health, bioidentical hormone therapy, pelvic electrical stimulation device therapy for urinary leakage and female sexual dysfunction. Breast cancer risk assessment, hormone therapy, menopause and related medical problems, menstrual disorders and interdisciplinary women's health, osteoporosis, menopause and women's health

Awards & Honors

  • Healthnetwork Service Excellence Award, 2010
  • Best Doctors, Cleveland magazine, 1998, 2002, 2004, 2006-2014
  • Best Doctors in America, 1998, 2000-2002, 2007, 2008
  • Cleveland Clinic Women's Health Center Top Executive, Women's Health Services, 2007
  • Legal Resolution from Cuyahoga County Commissioners on Local and National Leadership in Women’s Health, 2006
  • Research Program of the Year. Bone Disease Program. Thacker HL et al. Recognized for multidisciplinary work. Notations newsletter of Cleveland Clinic Lerner Research Institute,, 7/21/2005
  • Who's Who in Health, Crain's Cleveland Business, 2002$0$0Distinguished Women in Health Care, first annual listing from the Visiting Nurse Association, 2000
  • Top 40 Under Age 40, Crain's Cleveland Business, 1998$0$0Achievement in Health/Medicine, Northern Ohio Live magazine, "in recognition of outstanding contributions to the quality of life in this region,” 1998


  • Ohio State Medical Association elected Councilor 2014-2016
    North American Menopause Society
Research & Publications

Research & Publications

See publications for Holly L. Thacker, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 2/11/2020, Dr. Thacker has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Consulting and/or Speaking. Dr. Thacker receives fees of $5,000 or more per year as a paid consultant, speaker or member of an advisory committee for the following companies:

  • TherapeuticsMD, Inc.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

164 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.8 out of 5
Explains 4.8
Courtesy, Respect & Concern 4.8
Patient Rating of Doctor 4.8

49 Patient Comments

Reviewed on Feb 27, 2020

My first visual appt! Seeing Dr. Thacker was great. She is thorough and her staff the best! I am still waiting to hear back from Rhonda to set up my appointments. May call again, knowing her heavy work load. She always calls back fast, so maybe I did not get my message through. GREAT! #1 DOCTOR!!

Reviewed on Feb 14, 2020

Dr. Thacker really cares. When I leave, I feel as though I have a great understanding of my treatment as she takes the time to answer every question I have and addresses any concerns I may have. I wish every experience I had with a doctor made me feel like a person, and not like they have a quota to see as many patients as possible.

Reviewed on Feb 10, 2020

one of the best doctors i have ever visited. knows your history and helps on every avenue.

Reviewed on Jan 14, 2020

It was good. Did not have to wait Liked Dr.Thucker, she is great!

Reviewed on Jan 13, 2020

Dr. Holly Thacker is very competent and professional while at the same time displaying a level of concern that is above and beyond. Thank You Dr. Thacker!

Reviewed on Dec 31, 2019

Holly Thacker is an excellent, knowledgeable and personable provider.

Reviewed on Dec 12, 2019

Dr Thacker is very knowledgeable, direct, asks many questions, listens

Reviewed on Dec 12, 2019

Dr Thacker and staff were excellent. I would highly recommend

Reviewed on Dec 5, 2019

i was very pleased with my experience seeing Dr Thacker

Reviewed on Dec 5, 2019

i have always felt Dr Thacker was excellent at her profession this visit I was actually more impressed as she spent more time then usual with me and was very attentive to my concerns..even though I was not compliant from our last meeting which was 10 yrs ago. I work with women on a daily basis and always recommend Dr Thacker and the Women's Health Institute for their concerns. I felt my primary care provider was ok to treat my symptoms until recently.

Reviewed on Dec 3, 2019

it was a good experience except that I didn't care the way that Dr. Thacker would asked me questions and never looked up from her computer when I gave her an answer she just kept typing.I am old school and not comfortable with doctors and I realize this is the new way I would've liked it better if she just sat down and talk to me without all of the typing going on.

Reviewed on Nov 12, 2019

Rhonda Jackson does the best at scheduling appointments. She always makes you feel like you are her first priority. I can't say enough about Dr Thacker. She is compassionate about the health and well being of her patients. I feel truly blessed that I am her patient.

Reviewed on Oct 29, 2019

Dr Thacker is a very personable caring Physician.

Reviewed on Sep 24, 2019

i have traveled from Erie Pa for 10 years to see Dr. Thacker for Women's Health at menopause. There is no services in our area that compare in any way. Dr. Thacker's expertise and clinical management has been exceptional in each interaction, and this time was no exception. This visit was 1:1, an updated assessment done, changes were made & an after visit summary immediately provided. I have shared Dr Thacker's book on Menopause & referred friends to the Women's Health service.

Reviewed on Sep 17, 2019

dr Thacker was the first women's health dr who genuinely wanted to provide solutions to my concerns. she addressed them directly and thoughtfully. she speaks quickly but it's obvious she just wants to convey an extraordinary amount of information in a short time frame. she alleviated my concerns about hormones and explained the risks verses the benefits. I have already recommended her to others. in fact I was a referral from another friend

Reviewed on Sep 16, 2019

Dr. Thacker is the gold standard of medical care ! Her knowledge, professionalism, thoroughness of care are combined with a sincere personal care for her patients.

Reviewed on Sep 6, 2019

Doctor Thacker and her assistant Rhonda are great.

Reviewed on Sep 6, 2019

Doctor Thacker was and always is very knowledgeable

Reviewed on Aug 29, 2019

Dr. Thacker is the best .

Reviewed on Aug 20, 2019

I have referred her to many friends and family members already. She was awesome!! Dr Thacker was interested in what I asked about and to find a solution!

Reviewed on Jul 19, 2019

Dr Thacker was amazing. She was vibrant, professional, compassionate and knowledgeable. I especially appreciated her attention to detail and to the research supporting my questions concerning hormone replacement therapy. It was one of my best experiences at Cleveland Clinic. Her care was, indeed, World-Class. I would highly recommend her. I left her office feeling well cared for and extremely informed.

Reviewed on Jul 19, 2019

As mentioned earlier, Dr. Thacker exemplifies the "World Class Care" that Cleveland Clinic promotes. She was vibrant, engaged, knowledgeable and sensitive to my needs and concerns

Reviewed on Jul 19, 2019

I have already recommended Dr. Thacker to one of my colleagues at the University. I guess that speaks volumes

Reviewed on Jun 24, 2019

I'm glad my research paid off by selecting Dr Thacker. I intended to maintain my previous OB/gyn and have Dr Thacker supplement for the one reason I made the appt. No need. She is my new and only doctor.

Reviewed on Jun 20, 2019

love dr. Thacker

Reviewed on Jun 11, 2019

Excellent physician

Reviewed on Jun 6, 2019

Dr. Thacker is an incredibly talented and passionate physician. She provides the very best care to all of her patients. She is a wonderful doctor and Cleveland Clinic is very lucky to have her on the team.

Reviewed on Jun 4, 2019

Dr Thacker is an astute and meticulous physician. I am grateful to be her patient!

Reviewed on May 31, 2019

The staff along with Dr. Holly Thacker have been nothing but professional, courteous, and friendly, have a great experience every time I've visited.

Reviewed on May 21, 2019

Dr. Thacker is an excellent doctor. Not only is she excellent, but so are the other staff members that she works with. I never feel rushed when I am with her. She allows me needed time to ask questions or address any concerns I may have. She takes time to go over test results along with future orders and upcoming appointments. She truly cares for patients and their overall health and wellness. I am so happy to call her my doctor.

Reviewed on May 17, 2019

Dr. Thacker has always been thorough in her explanations. She has a wonderful woman's web site I use too!

Reviewed on May 7, 2019

Dr. Thacker is amazing! She looked at me as a whole person and really helped me in many ways. She was so kind and considerate as well!

Reviewed on May 6, 2019

I have already recommended Dr. Thucker, she is the expert in this field and also caring.

Reviewed on May 3, 2019

Dr Holly Thacker is amazing! she is professional, friendly, thorough, cutting edge. there is no better!

Reviewed on May 3, 2019

One note - Dr. Thacker needs to slow down when she is talking - I'm fine with asking questions or stopping and telling her to repeat - but I'm probably not the norm in that respect. I do love meeting with her she's clearly an expert in her area and provides great guidance and advice - just slow it down a bit :)

Reviewed on Apr 30, 2019

Dr Thacker 's knowledge and caring have far surpassed any other I have experienced in my life..she if as truly changed my life and thankful to have the privilege of her treatment

Reviewed on Apr 25, 2019

Dr. Holly and her "fellow" at this visit were very knowledgeable and worked together very well to help find the best plan for my situation. As I get to know Dr. Holly a little more at each visit, I become more comfortable with her and very confident in her ability to give me the best treatment available. I'm thankful.

Reviewed on Apr 23, 2019

wonderful doctor and staff!!

Reviewed on Apr 16, 2019

LOve DR. THacker and her nurses

Reviewed on Apr 8, 2019

dr. was easy to talk to. very knowledgeable. answered all my question

Reviewed on Apr 8, 2019

Dr. Thacker was like talking to a caring encyclopedia with a wealth of experience and knowledge. She was able to explain in language that I could understand.

Reviewed on Apr 8, 2019

I have already recommended Dr Thacker to my sister and several girl friends.

Reviewed on Apr 8, 2019

Everyone I encountered at the Cleveland Clinic was friendly and eager to assist from the Dr Thacker to the lab folks to the shuttle drivers.

Reviewed on Apr 4, 2019

Dr. Thacker and her team made me feel very comfortable and explained everything thoroughly.

Reviewed on Apr 1, 2019

Always a great experience with Dr. Thacker, as she is always personable, courteous, patient with me and is knowledgeable about my health information and whatever current situation. Just like every Physician, Nurse, Techs and Administrative Staff Personnel was during Dr. Floyd Loop's tenure, she never downplays, disregard or ignore my interpretation of what I am experiencing or going through. She has an incredible bedside manner and I appreciate her for that.

Reviewed on Mar 25, 2019

Wonderful experience overall. Dr. Thacker and all the staff made my visit a very pleasant one.

Reviewed on Mar 25, 2019

I have a lot of faith in Dr. Thacker. She has help me a lot with my overall health.

Reviewed on Mar 19, 2019

Dr. Thacker and her staff are fabulous. professional, very kind, accommodating and knowledgeable. Rhonda Jackson and Lillie are SUPER, too!

Reviewed on Mar 19, 2019

Dr Thacker is an excellent doctor. I recommend her to other patients. She is trustworthy n very competent. I know that she has read my file, listen to my concerns, n makes the best recommendation. I am grateful for her. She is ready to answer all my questions.

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