Department Subspecialty Care for Women’s Health
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English
Surgeon No
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus


Additional Locations

Specialties & Treatments

Treatment & Services

  • Bioidentical Hormone Therapy
  • Bone Density Testing
  • Breast Cancer Risk Assessment
  • Cervical Polypectomy
  • Endometrial Biopsy
  • Interdisciplinary Women's Health
  • IV Reclast Infusion For Postmenopausal Osteoporosis
  • Menopausal Risk Assessment
  • Specialty Women's Health
  • Vertebral Fracture Assessment
  • Women's Health
View all 11 Treatment & Services +

Specialty in Diseases & Conditions

  • Menopause
  • Osteopenia
  • Osteoporosis
  • Perimenopause Symptoms
  • Sexual Dysfunction
  • Sexual Hormone disorders
  • Vaginal Atrophy
View all 7 Specialties +


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About Holly L. Thacker, MD

Holly L. Thacker MD, FACP, director of the Cleveland Clinic Center for Specialized Women’s Health and Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University. She published her second women’s health book “Cleveland Clinic Guide to Menopause.”  Dr. Thacker is the Executive Director of national Speaking of Women's Health and directs the digital platform and directs CustomFit Physicals for women.

She was honored by the American Medical Women’s Association (AMWA) and the Journal of Women’s Health with the "Lila Wallis Women’s Health Award" in recognition of Dr. Thacker’s lifetime achievements, accomplishments, motivation, mentorship, energy and enthusiasm for women’s health, education, and research during the AMWA annual meeting and Women’s Health 2009: The 17th Annual Congress, in Williamsburg, VA.

In the Center for Specialized Women’s Health, we pursue leading edge and interdisciplinary therapies for women with a focus on menopausal and hormone risk assessment and therapies. We have started CustomFit Physicals for women to provide a uniquely personalized healthcare service that combines convenience and comprehensiveness in a one day visit with the service of a nurse navigator.  In addition, there are several new FDA approved pelvic floor stimulators that are available for women with urine leakage and pelvic muscle weakness as well as fecal incontinence and mild degrees of pelvic organ prolapse. These new pelvic floor stimulation devices are custom-fit and use stimulation to strengthen pelvic floor muscles and inhibit overactive bladder muscles while giving visual biofeedback and audible guidance. Precise adjustments can be made to ensure effective muscle training. Some women, who have only stress urinary leakage, and/or are 6 weeks post partum from vaginal delivery, may need simpler devices and all therapies can be done in the comfort and privacy of ones home. These devices can compliment, or in many cases be used instead of surgery or medications.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Residency - Cleveland Clinic
Internal Medicine
Cleveland, OH USA

Internship - Cleveland Clinic
Medical Internship
Cleveland, OH USA

Medical Education - University of Missouri-Kansas City School of Medicine
Kansas City, MO USA

Undergraduate - University of Missouri-Kansas City School of Medicine
Kansas City, MO USA

Professional Highlights

  • Author of the book, The Cleveland Clinic Guide to Menopause, a Cleveland Clinic Guide, © 2009
  • Author of the book, Women's Health: Your Body, Your Hormones, Your Choices, a Cleveland Clinic Guide, © 2007
  • Founder and Director of Women's Health Fellowship


  • Internal Medicine

Specialty Interests

Breast cancer risk assessment, hormone therapy, menopause and related medical problems, menstrual disorders and interdisciplinary women's health, osteoporosis, menopause, women's health, bioidentical hormone therapy, pelvic electrical stimulation device therapy for urinary leakage and female sexual dysfunction. Breast cancer risk assessment, hormone therapy, menopause and related medical problems, menstrual disorders and interdisciplinary women's health, osteoporosis, menopause and women's health

Awards & Honors

  • Healthnetwork Service Excellence Award, 2010
  • Best Doctors, Cleveland magazine, 1998, 2002, 2004, 2006-2014
  • Best Doctors in America, 1998, 2000-2002, 2007, 2008
  • Cleveland Clinic Women's Health Center Top Executive, Women's Health Services, 2007
  • Legal Resolution from Cuyahoga County Commissioners on Local and National Leadership in Women’s Health, 2006
  • Research Program of the Year. Bone Disease Program. Thacker HL et al. Recognized for multidisciplinary work. Notations newsletter of Cleveland Clinic Lerner Research Institute,, 7/21/2005
  • Who's Who in Health, Crain's Cleveland Business, 2002$0$0Distinguished Women in Health Care, first annual listing from the Visiting Nurse Association, 2000
  • Top 40 Under Age 40, Crain's Cleveland Business, 1998$0$0Achievement in Health/Medicine, Northern Ohio Live magazine, "in recognition of outstanding contributions to the quality of life in this region,” 1998


  • Ohio State Medical Association elected Councilor 2014-2016
    North American Menopause Society
Research & Publications

Research & Publications

See publications for Holly L. Thacker, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 2/11/2020, Dr. Thacker has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Consulting and/or Speaking. Dr. Thacker receives fees of $5,000 or more per year as a paid consultant, speaker or member of an advisory committee for the following companies:

  • TherapeuticsMD, Inc.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

251 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.8 out of 5
Explains 4.8
Courtesy, Respect & Concern 4.8
Patient Rating of Doctor 4.8

76 Patient Comments

Reviewed on Aug 18, 2020

Everyone is over worked.More staff in the whole Clinic would be good.Holly Thacker is a wonderful, personable, knowledgeable physician. I'm in good hands.

Reviewed on Aug 4, 2020

Dr. Thacker is a force to be reckoned with. :) I admired her confidence and her ability to clearly articulate a plan for my health.

Reviewed on Aug 4, 2020

Rhonda in Dr. Thacker's office is terrific. She accommodated my request for an early morning appointment.

Reviewed on Aug 4, 2020

Dr. Thacker always asks questions to get to the best diagnosis.

Reviewed on Aug 4, 2020

Dr. Thacker included a Fellow. I like that. I feel like I am contributing to a physician's training & I get the advantage of another medical opinion.

Reviewed on Aug 3, 2020

best dr. for hormone balancing. great listener and forward thinking.

Reviewed on Jul 28, 2020

I'm an RN and I was extremely impressed by dr. Thackers knowledge. I feel like I finally found someone who listens, cares, and treats the issues I'm having. I'm very thankful my small hometown dr referred me to her.

Reviewed on Jul 27, 2020

I did feel a bit overwhelmed by the whole visit with the doctor. It was my first visit and the masks definitely didn't help. My doctor knew all the information about how to treat me, but I couldn't even think of questions for her because of nerves and the feeling of being overwhelmed by all the information. I almost got the feeling that I should understand everything immediately and not need to ask questions. That being said, since I was nervous, I will see her again and hope the visit goes better.

Reviewed on Jul 23, 2020

Dr. Thacker was very thorough and is an overall outstanding physician.

Reviewed on Jul 23, 2020

was exceptional good doctor and staff

Reviewed on Jul 23, 2020

the staff and doctor were professional, very knowledgeable and Dr. was extremely focused

Reviewed on Jul 21, 2020

Dr Thacker office was prompt reaching out and following up which gave me peace of mind and made me feel heard.

Reviewed on Jul 21, 2020

I love Dr Thacker and would be devasted if she retired! Ive never met or had a doctor so versed in Womens Health and so eager to share with the patient. Dr Thacker provides the information I need to make informed decisions about my health. Dr Thacker listens I feel heard and am treated as a partner in my health care. Dr Thacker knowledge experience and passion has be invaluable so I view her as a trusted health care provider.

Reviewed on Jul 16, 2020

So easy to see the doctor by getting in due to a cancellation.

Reviewed on Jul 16, 2020

I cannot emphasize enough how much I respect Dr. Thacker. She is wonderful.

Reviewed on Jul 7, 2020

Dr. Thacker could not have been more concerned for my health and concerns. She showed the utmost courtesy and gave freely if her time to respond to questions. She is very knowledgeable. Best experience with a physician I have ever had. Would recommend her without hesitation.

Reviewed on Jul 2, 2020

Dr. Thacker was thorough in explaining what was going on and what I needed to do

Reviewed on Jul 2, 2020

Dr. Smith made me feel comfortable, also.

Reviewed on Jul 2, 2020

I love *Dr. Thacker! She is caring & kind. She really listens to you & finds the best treatment for your condition.

Reviewed on Jul 2, 2020

dr Thacker. is amazing. I am so glad to have her as my doctor

Reviewed on Jun 30, 2020

Dr. Thacker is a wonderful, caring person, and her scheduling nurse is especially well organized.

Reviewed on Jun 30, 2020

Dr. Thacker is an excellent caretaker.

Reviewed on Jun 25, 2020

I felt like the visit was a little rushed ... though the provider is very good at what she might be the energy she has.

Reviewed on Jun 19, 2020

Dr. Thacker secretary Rhonda is amazing. She is outstanding with customer service.

Reviewed on Jun 19, 2020

I've always felt I'm under the best of care as one of Dr. Holly Thacker's patients!

Reviewed on Jun 19, 2020

Dr. Holly Thacker is among the best, I refer all my girlfriends to her. I feel she is the best women's advocate and renown for it!

Reviewed on Jun 16, 2020

Dr Thacker's the reason I come from out of state to the Clinic. She's one of the best doctors I ever had.

Reviewed on Jun 15, 2020

Dr Thacker is brilliant, but also kind & compassionate. I'm grateful she is one of my physicians. She goes above and beyond my GYN health. She provides wholistic care!

Reviewed on Jun 11, 2020

I love dr Thacker she is so smart and knows just what to do to treat me. she even reminds me when I am late for my other health screens and immuinzations she reviews my chart and my medications for interactions. she really is a GREAT doctor. I have referred her to my family & friends and they all are very happy with her care. I hope to see her for the rest of my life.

Reviewed on Jun 5, 2020

Dr Thacker was so patient and really took the time to speak to me and made sure I understood everything about my health. She has such a wealth of information and I feel goes beyond just the questions that are specific to the issue, she asks questions to get a whole picture of who I am and how my overall health is. She's amazing!

Reviewed on Jun 4, 2020

I just love Dr. Thacker's candor and knowledge about women's health! I know she truly cares! This was my first visit with Dana Leslie. Ms. Leslie was excellent! She made me feel very comfortable and was very pleasant. The women, I think Pauline or Paulette that performed my mammogram was a delight! She made such an uncomfortable exam as best as it could be. Thank you!

Reviewed on Jun 4, 2020

I'm very impressed with Dr Thaker. She's very knowledgeable, caring and professional. You feel very at ease to discuss any intimate concerns. I've been leaving abroad (Canada, Abu Dhabi and Switzerland). She's by far the best.

Reviewed on Jun 1, 2020

dr. Thacker was very thorough and really helped me out

Reviewed on May 28, 2020

my experience with Dr. Thacker has always been an excellent experience. she explains everything in detail and review long term goals

Reviewed on May 21, 2020

Dr. Thacker is the best of the best. Her assistant, Miss Rhonda absolutely saved me when the app didn't work after 3 attempts. She was patient, calmed me down from the point of tears due to frustration. So many thanks for her help.

Reviewed on May 21, 2020

Thank God for Dr. Holly. She transformed my miserable entrance to peri menopause a graceful, manageable transition.

Reviewed on May 21, 2020

Miss Rhonda the perfect compliment to Dr. Thacker. Both of them. Grace and intelligence.

Reviewed on May 21, 2020

Dr. Thacker is an amazing physicial and is an expert in her field! That's why I chose her to assist me through my challenges of perimenopause through menopause. The only suggestion is that she can speak very, very quickly and the thoughts, ideas and directions she gives me during the appointment don't often make it onto the after visit summary. And then I have to call back and clarify some things with a nurse. Perhaps I need to take better notes but the appointments go very fast.

Reviewed on May 18, 2020

Dr Thacker has been my physician for many years. When I first went to Dr Thacker, I had many female issues that other physicians did not completely find resolutions for. Dr Thacker has been a God send to me. With her care, I have made wonderful gains & have improved in all area that were of concern. I am 71 & walk 3 miles everyday & play Pickleball at least three times a week. I owe my vitality to Dr Thacker. I recommend her to all my friends

Reviewed on May 12, 2020

Rhonda, scheduler for Dr. Thacker, is of the highest caliber of schedulers I have had the pleasure to talk with at CCF. Her attention to detail and the concerns for patients and the "Never forget you" attitude makes her an OUTSTANDING Employee! 5 star!

Reviewed on May 12, 2020

Dr. Thacker is a true gem of a caring and empathetic doctor! Her care is truly outstanding, and she really cares and checks on the totality of the well-being of her patients! I wish all doctors were as thorough, caring, empathic, and kind as Dr. Thacker! Dr. Thacker is truly outstanding and a superior care provider! Dr. Thacker, Lily, and Rhonda all deserve a special kudos, recognition, extra praise, and incentives for the dedication and care for all women and their health & well being! Thank you to Dr. Thacker and her team!

Reviewed on May 12, 2020

I have recommended and told others about Dr. Thacker, her team, and her helpful website!

Reviewed on May 12, 2020

Dr. Thacker is more thorough during a video visit than most physicians are during an in person one. She covers every base & doesn't miss a beat. She cares about your well being as a person & isn't just doing her job. She genuinely wants to solve the problem so she will ask the pertinent questions necessary and move accordingly.

Reviewed on May 12, 2020

Dr. Thacker's nurse Lillie is commendable. After my visit, she called me & made sure I understood the instructions I was given & let me know she was following up with paperwork in the mail. Things that could easily be overlooked are treated with concern in Dr. Thacker's Women's Health Clinic and it's because of nurses like Lillie who care about the patients.

Reviewed on May 8, 2020

Very impressed with the Women's Health Center! Everyone is so helpful and pleasant. I'm beyond impressed with Dr. Holly Thacker!! I've been to many nice doctor's over the years, but always left with some uncertainty. Dr. Thacker far exceeded my expectations! She is extremely thorough!! I FINALLY found a decent dr!! I'm so thrilled that my healthcare is in good hands!!

Reviewed on May 8, 2020

Dr. Thacker is very concerned about her patients well being

Reviewed on Apr 28, 2020

Dr. Thacker is Superb!!

Reviewed on Apr 28, 2020

Thacker has the worst bedside manner of any physician I have ever encountered. She was condescending and a poor listener - bad habits indulged or ignored by employers up until now that are now character flaws which impede the effective practice of medicine.

Reviewed on Apr 27, 2020

i have recommended Dr Thacker to my friends and they became her patients.

Reviewed on Apr 27, 2020

I have already recommended this provider to friends.

Reviewed on Apr 23, 2020

I actually came to clinic for bone density test and mammogram and Dr. Thacker made time to do an appointment for me so I didn't have to come back. I live 1 hour away

Reviewed on Apr 16, 2020

Dr. Thacker is very helpful and caring and truly understands what women need/want in regards to a persons sexual health, especially. Thank You!

Reviewed on Apr 14, 2020

Dr. Thacker was very thorough in gathering information from me and made me comfortable that she was taking a comprehensive and holistic approach to my overall health. She was extremely knowledgeable and provided me with great resources to learn more about my concerns.

Reviewed on Apr 2, 2020

Rhonda in Dr. Thacker's officeis unbelievably prompt,responsive and accommodating. I was so very impressed.

Reviewed on Apr 2, 2020

Dr. Thacker was so knowledgeable and certain about treatment and next steps-it gave me great confidence and I was so very glad I'd sought her counsel.

Reviewed on Apr 2, 2020

I am aware of Dr. Thacker's reputation and was surprised at how easy it was to get an appointment and her willingness to spend so much time during our conversation. Shewas so very thorough and proactive about my care. I am very grateful.

Reviewed on Apr 2, 2020

Excellent physician

Reviewed on Mar 31, 2020

dr. Thacker is always kind and thorough! She is very competent!

Reviewed on Feb 27, 2020

My first visual appt! Seeing Dr. Thacker was great. She is thorough and her staff the best! I am still waiting to hear back from Rhonda to set up my appointments. May call again, knowing her heavy work load. She always calls back fast, so maybe I did not get my message through. GREAT! #1 DOCTOR!!

Reviewed on Feb 14, 2020

Dr. Thacker really cares. When I leave, I feel as though I have a great understanding of my treatment as she takes the time to answer every question I have and addresses any concerns I may have. I wish every experience I had with a doctor made me feel like a person, and not like they have a quota to see as many patients as possible.

Reviewed on Feb 10, 2020

one of the best doctors i have ever visited. knows your history and helps on every avenue.

Reviewed on Jan 14, 2020

It was good. Did not have to wait Liked Dr.Thucker, she is great!

Reviewed on Jan 13, 2020

Dr. Holly Thacker is very competent and professional while at the same time displaying a level of concern that is above and beyond. Thank You Dr. Thacker!

Reviewed on Dec 31, 2019

Holly Thacker is an excellent, knowledgeable and personable provider.

Reviewed on Dec 12, 2019

Dr Thacker is very knowledgeable, direct, asks many questions, listens

Reviewed on Dec 12, 2019

Dr Thacker and staff were excellent. I would highly recommend

Reviewed on Dec 5, 2019

i was very pleased with my experience seeing Dr Thacker

Reviewed on Dec 5, 2019

i have always felt Dr Thacker was excellent at her profession this visit I was actually more impressed as she spent more time then usual with me and was very attentive to my concerns..even though I was not compliant from our last meeting which was 10 yrs ago. I work with women on a daily basis and always recommend Dr Thacker and the Women's Health Institute for their concerns. I felt my primary care provider was ok to treat my symptoms until recently.

Reviewed on Dec 3, 2019

it was a good experience except that I didn't care the way that Dr. Thacker would asked me questions and never looked up from her computer when I gave her an answer she just kept typing.I am old school and not comfortable with doctors and I realize this is the new way I would've liked it better if she just sat down and talk to me without all of the typing going on.

Reviewed on Nov 12, 2019

Rhonda Jackson does the best at scheduling appointments. She always makes you feel like you are her first priority. I can't say enough about Dr Thacker. She is compassionate about the health and well being of her patients. I feel truly blessed that I am her patient.

Reviewed on Oct 29, 2019

Dr Thacker is a very personable caring Physician.

Reviewed on Sep 24, 2019

i have traveled from Erie Pa for 10 years to see Dr. Thacker for Women's Health at menopause. There is no services in our area that compare in any way. Dr. Thacker's expertise and clinical management has been exceptional in each interaction, and this time was no exception. This visit was 1:1, an updated assessment done, changes were made & an after visit summary immediately provided. I have shared Dr Thacker's book on Menopause & referred friends to the Women's Health service.

Reviewed on Sep 17, 2019

dr Thacker was the first women's health dr who genuinely wanted to provide solutions to my concerns. she addressed them directly and thoughtfully. she speaks quickly but it's obvious she just wants to convey an extraordinary amount of information in a short time frame. she alleviated my concerns about hormones and explained the risks verses the benefits. I have already recommended her to others. in fact I was a referral from another friend

Reviewed on Sep 16, 2019

Dr. Thacker is the gold standard of medical care ! Her knowledge, professionalism, thoroughness of care are combined with a sincere personal care for her patients.

Reviewed on Sep 6, 2019

Doctor Thacker and her assistant Rhonda are great.

Reviewed on Sep 6, 2019

Doctor Thacker was and always is very knowledgeable

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