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Department Subspecialty Care for Women's Health
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English
Surgeon No
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus


Additional Locations

Specialties & Treatments

Treatment & Services

  • Bioidentical Hormone Therapy
  • Bone Density Testing
  • Breast Cancer Risk Assessment
  • Cervical Polypectomy
  • Endometrial Biopsy
  • IV Reclast Infusion for Postmenopausal Osteoporosis
  • Menopausal Risk Assessment
  • Vertebral Fracture Assessment
  • Women's Health
View all 9 Treatment & Services +

Specialty in Diseases & Conditions

  • Menopause
  • Osteopenia
  • Osteoporosis
  • Perimenopause Symptoms
  • Sexual Dysfunction
  • Sexual Hormone Disorders
  • Vaginal Atrophy
View all 7 Specialties +


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About Holly L. Thacker, MD

Holly L. Thacker MD, FACP, director of the Cleveland Clinic Center for Specialized Women’s Health and Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University. She published her second women’s health book “Cleveland Clinic Guide to Menopause.”  Dr. Thacker is the Executive Director of national Speaking of Women's Health and directs the digital platform www.speakingofwomenshealth.com and directs CustomFit Physicals for women.

She was honored by the American Medical Women’s Association (AMWA) and the Journal of Women’s Health with the "Lila Wallis Women’s Health Award" in recognition of Dr. Thacker’s lifetime achievements, accomplishments, motivation, mentorship, energy and enthusiasm for women’s health, education, and research during the AMWA annual meeting and Women’s Health 2009: The 17th Annual Congress, in Williamsburg, VA.

In the Center for Specialized Women’s Health, we pursue leading edge and interdisciplinary therapies for women with a focus on menopausal and hormone risk assessment and therapies. We have started CustomFit Physicals for women to provide a uniquely personalized healthcare service that combines convenience and comprehensiveness in a one day visit with the service of a nurse navigator.  In addition, there are several new FDA approved pelvic floor stimulators that are available for women with urine leakage and pelvic muscle weakness as well as fecal incontinence and mild degrees of pelvic organ prolapse. These new pelvic floor stimulation devices are custom-fit and use stimulation to strengthen pelvic floor muscles and inhibit overactive bladder muscles while giving visual biofeedback and audible guidance. Precise adjustments can be made to ensure effective muscle training. Some women, who have only stress urinary leakage, and/or are 6 weeks post partum from vaginal delivery, may need simpler devices and all therapies can be done in the comfort and privacy of ones home. These devices can compliment, or in many cases be used instead of surgery or medications.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Residency - Cleveland Clinic
Internal Medicine
Cleveland, OH USA

Internship - Cleveland Clinic
Medical Internship
Cleveland, OH USA

Medical Education - University of Missouri-Kansas City School of Medicine
Kansas City, MO USA

Undergraduate - University of Missouri-Kansas City School of Medicine
Kansas City, MO USA

Professional Highlights

  • Author of the book, The Cleveland Clinic Guide to Menopause, a Cleveland Clinic Guide, © 2009
  • Author of the book, Women's Health: Your Body, Your Hormones, Your Choices, a Cleveland Clinic Guide, © 2007
  • Founder and Director of Women's Health Fellowship


  • Internal Medicine

Specialty Interests

Breast cancer risk assessment, hormone therapy, menopause and related medical problems, menstrual disorders and interdisciplinary women's health, osteoporosis, menopause, women's health, bioidentical hormone therapy, pelvic electrical stimulation device therapy for urinary leakage and female sexual dysfunction. Breast cancer risk assessment, hormone therapy, menopause and related medical problems, menstrual disorders and interdisciplinary women's health, osteoporosis, menopause and women's health

Awards & Honors

  • Healthnetwork Service Excellence Award, 2010
  • Best Doctors, Cleveland magazine, 1998, 2002, 2004, 2006-2014
  • Best Doctors in America, 1998, 2000-2002, 2007, 2008
  • Cleveland Clinic Women's Health Center Top Executive, Women's Health Services, 2007
  • Legal Resolution from Cuyahoga County Commissioners on Local and National Leadership in Women’s Health, 2006
  • Research Program of the Year. Bone Disease Program. Thacker HL et al. Recognized for multidisciplinary work. Notations newsletter of Cleveland Clinic Lerner Research Institute, www.lerner.ccf.org/notations, 7/21/2005
  • Who's Who in Health, Crain's Cleveland Business, 2002$0$0Distinguished Women in Health Care, first annual listing from the Visiting Nurse Association, 2000
  • Top 40 Under Age 40, Crain's Cleveland Business, 1998$0$0Achievement in Health/Medicine, Northern Ohio Live magazine, "in recognition of outstanding contributions to the quality of life in this region,” 1998


  • Ohio State Medical Association elected Councilor 2014-2016
  • North American Menopause Society
Research & Publications

Research & Publications

See publications for Holly L. Thacker, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 4/2/2024, Dr. Thacker has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

382 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.7 out of 5
Explains 4.7
Courtesy, Respect & Concern 4.7
Patient Rating of Doctor 4.7

78 Patient Comments

Reviewed on May 6, 2024

I absolutely love my Dr. Dr. Thacker is the best

Reviewed on May 2, 2024

Dr Thacker is an excellent doctor. I wish it hadn't taken me so long so find her!

Reviewed on Apr 23, 2024

Dr. T is thorough, listens to concerns, and finds a mutually agreeable solution.

Reviewed on Apr 23, 2024

Dr Thacker & her team are amazing. I've had an issue without answers for four years and was able to finally get an answer this visit, after working on it for two years with Dr Thacker. I drive 2.5 hours because the level of care is exceptional. I have recommended Dr Thacker's office & the clinic to so many people because the level of care is just so far beyond what I've experienced in Columbus. Thank you so much for all that you do!

Reviewed on Apr 18, 2024

Dr. Thacker was very thorough with her explanation and what our care plan will be.

Reviewed on Apr 18, 2024

Dr. Thacker is a very thorough and kind doctor

Reviewed on Apr 2, 2024

Answered all my questions, was professional, caring and knowledgeable. Both the Fellow and Dr. Thacker. I felt validated and cared for as a whole person and not just a number. It was a great experience. Great resources provided for personal education after visit which I have been utilizing such as podcasts and websites.

Reviewed on Mar 29, 2024

Dr. Thacker is one of the doctors on my care team and she is AMAZING and really cares about my health concerns!

Reviewed on Mar 25, 2024

The nurse was great. The doctor not so much.

Reviewed on Mar 22, 2024

She was extremely informative and so kind. She came up with a plan to help me with short-term and long-term and connected me with all of the proper specialists to address my current issues. I feel that this is top level care and she is a doctor that I will be recommending to every woman I know who is struggling with their healthcare.

Reviewed on Mar 21, 2024

Dr Thacker is kind and the best Dr. She cares about your whole body and that everything is going well for you. She takes the time to explain everything to you in a way you can understand. She always asks if you have any questions or concerns and if you understood everything. I never feel rushed. I enjoy my appointments with her.

Reviewed on Mar 18, 2024

Dr Thacker is an excellent combination of being socially engaging and an expert at presenting her medical recommendations based on science

Reviewed on Mar 15, 2024

Very good. Dr. Thacker listened closely to my concerns and was very understanding and supportive of my situation and individual needs. She is also very knowledgeable about more natural treatment options, which is why I chose to go to her.

Reviewed on Mar 5, 2024

Dr. Thacker is excellent, but it is very challenging to get an appointment

Reviewed on Mar 5, 2024

Very curt in regards to disposition. Always in a hurry and dismissive-to all those around her including nurses, patients, residents, etc. No bedside manner at all.

Reviewed on Mar 1, 2024

I have had Dr. Thacker for many years. I am used to seeing her in the office. I am used to her fast talking and typing at the same time. This video visit was not great in so far as the volley of conversation was difficult. She really did not seem to be on her game!

Reviewed on Feb 23, 2024

Dr Thacker is nice, smart, takes her time with her patience and very thorough. She is just amazing and really cares for her patience. She understands woman health like no other. I always love to see her- she helps me in so many ways. She is a gem of a doctor- always answers my chart in a timely manner too.

Reviewed on Feb 22, 2024

Holly Thacker is a wonderful doctor, and I am fortunate to have her. So many doctors come and go but Holly has been with me for over 25 years.

Reviewed on Feb 20, 2024

When asked about other options besides hormones she recommended I listen to her podcast

Reviewed on Feb 13, 2024

She is an exceptional well-rounded and helpful doctor!

Reviewed on Feb 2, 2024

Dr. Thacker appears rushed and anxious to get through the appointment.

Reviewed on Jan 19, 2024

Dr. Thacker takes time to listen to my concerns and provides appropriate treatment options, as well as guidance on non-Rx approaches like healthy sleep routine.

Reviewed on Jan 19, 2024

Dr. Thacker talks too fast and is too concerned if I have living will or have listened to her podcast. She assumes you understand everything she is saying and tells you to read your AVS twice, but fails to put in all that she discussed with you.

Reviewed on Jan 9, 2024

I am so grateful for Dr. Thacker! She has helped me take control of my health. She tells you what you need to hear and she truly cares! Thank you Dr. Thacker!

Reviewed on Jan 2, 2024

Dr Thacker is brilliant and clearly knows the best route for each woman through menopause! Her group sessions are informative while she listens and response to everything I say or ask. Fantastic!!! So very grateful to have access to her medical expertise!

Reviewed on Dec 21, 2023

Dr Thacker was fantastic. She took the time to speak to me about my concerns. She offered some solutions and we talked through them to find one I was most comfortable with.

Reviewed on Dec 18, 2023

I learned more in an hour+ with Dr. Thacker than months of research, visit to my own ob/gyn etc. She is truly a gift to the hospital and patients. She also has the ability to share in information in a way that is understandable and approachable to those without a medical background.

Reviewed on Dec 8, 2023

My appointment ran on time and Dr. Thacker was thorough and professional. She spent a lot of time with me and I felt like she sincerely cared about my health.

Reviewed on Dec 7, 2023

Dr Thacker spent a lot of time with me and discussed my list of questions and concerns. I was extremely happy with our conversation and next steps.

Reviewed on Dec 7, 2023

I already referred a friend to Dr Thacker. She drove all the way from Dayton and was very happy she did!

Reviewed on Dec 5, 2023

It was an excellent experience. Dr. Thacker has been my doctor for at least 20 yrs.

Reviewed on Nov 30, 2023

Dr Thacker is a great doctor, she follows up quickly and is extremely thorough with her exams

Reviewed on Nov 16, 2023

Dr. Thacker and her team were wonderful. I learned so much at this appointment and am feeling so much better since the visit and medication changes. I have recommended her to several people.

Reviewed on Nov 14, 2023

Dr Thucker is the best Doctor, she answered all my questions and liberated me from the stress and fear. Thank you from my entire family!

Reviewed on Nov 14, 2023

Holly Thacker is the best in her field and I am fortunate she is my doctor.

Reviewed on Nov 7, 2023

Dr. Thacker is very professional and answers all my questions and concerns.

Reviewed on Nov 7, 2023

I really enjoyed my time with Dr Thacker. She is a wonderful doctor and makes me feel very comfortable. I appreciate her very much!!

Reviewed on Nov 6, 2023

Busy physician. Takes a while to schedule.

Reviewed on Nov 3, 2023

So grateful for Dr. Thacker and her passion for HRT

Reviewed on Oct 30, 2023

I have recommended Dr Thacker and the Fit Physical to many women my age all over the us

Reviewed on Oct 30, 2023

I was able to connect easily through Dr Thacker's nurse and she followed up with me every step of the way

Reviewed on Oct 30, 2023

Amazing physician

Reviewed on Oct 17, 2023

Dr. Thacker is excellent

Reviewed on Oct 16, 2023

Television was difficult at first as I was unable to get my phone off mute. Dr. Thacker called me and the visit went fine after that. Technical difficulty was on my end.

Reviewed on Oct 16, 2023

Holly and her nurses were all excellent and kind ,patient.

Reviewed on Oct 13, 2023

The only and the best communication and education! Dr Holly is empathetic and engaged in offering the very best information, not just in my appointment, but also in continuing education through her website and her podcasts. Cleveland Clinic needs more physicians willing to spend the time and effort to inform & educate.

Reviewed on Oct 12, 2023

Dr. Thacker is one of the most knowledgeable and thorough physicians I have ever had. Highly recommend.

Reviewed on Oct 12, 2023

Dr. Thacker is a wonderful, caring physician. I feel very comfortable taking with her about any issues I have and feel she will do her best to make sure my issues are addressed. She is very thorough and professional. She is an exemplary physician in my opinion.

Reviewed on Oct 9, 2023

Dr Thacker is so knowledgeable! I feel that she really looks at all the smaller components, the details, that make up my overall health!

Reviewed on Sep 28, 2023

Dr. Thacker was wonderful! She addressed my concerns and was very thorough! I was very happy with the appointment!

Reviewed on Sep 27, 2023

I found Dr Thacker very helpful and informative.

Reviewed on Sep 21, 2023

Extremely knowledgeable. Honestly the best experience ever visiting a doctors office.

Reviewed on Aug 29, 2023

Dr Thacker is one of the best health care providers I have ever had. I credit her with my good health .

Reviewed on Aug 22, 2023

Dr Holly Thacker is an excellent doctor. She is thorough & up to date on all new medical treatments & procedures.

Reviewed on Aug 21, 2023

Dr Thacker is an incredibly knowledgeable and compassionate physician. I am so fortunate to be her patient, and I am so grateful to receive cutting edge, world class care from Dr Thacker and her team. I highly recommend her.

Reviewed on Aug 21, 2023

Dr. Thacker is Very thorough!! Didn't feel rushed ! Answered all my questions!! Trust her opinion explicitly!!

Reviewed on Aug 11, 2023

Dr Thacker is very knowledgeable. She spoke fast and I had trouble following but she circled back for me.

Reviewed on Aug 4, 2023

Dr Holly Thacker is a fantastic doctor so happy she is helping me feel better!

Reviewed on Jul 31, 2023

Dr. Thacker is very professional and listens to all your medical concerns. She Is very knowledgeable and personable. Thank you, Dr. Thacker

Reviewed on Jul 28, 2023

I have a great amount of respect for Dr. Thacker and her efforts to help me improve my health.

Reviewed on Jul 28, 2023

Very positive experience. Doctor Thacker was very thorough.

Reviewed on Jul 27, 2023

Dr Thacker is exceptional. Her expertise and explanation was very comforting. A truly gifted physician.

Reviewed on Jul 26, 2023

Dr Thacker is amazing! Whip smart & at the forefront of women's health issues. I value her opinion in all health matters & feel blessed to have found her many years ago. At every appointment I always learn something new relative to retaining my good health. I attribute much of my well being to her guidance & more recently to that of Dr Pederson as well. Both are friends as well as respected associates & have helped me in immeasurable ways.

Reviewed on Jul 25, 2023

Love Dr. Thacker and her team!

Reviewed on Jul 21, 2023

I am so grateful to be under Dr. Holly Thacker's care. I probably wouldn't be alive today if it weren't for her. Very, very, very grateful!

Reviewed on Jul 20, 2023

Dr. Thacker is the most thorough and informative doctor I have ever seen. I have spoke highly of her and referred her to others.

Reviewed on Jul 18, 2023

Dr. Thacker and staff have always shown care and taken time to explain my condition, the options available, and it was no different this time. I would gladly recommend Dr. Thacker to others.

Reviewed on Jul 17, 2023

Cleveland Clinic and the providers are above any provider I have seen in Erie PA where I live. Respect, care and knowledge of the medical issues I have been treated for outweigh any other provider I have visited.

Reviewed on Jul 13, 2023

I can't tell you how much I appreciate her as my doctor. Dr Thacker's knowledge on woman's health is not only impeccable, she cares about her patients wellbeing.

Reviewed on Jun 29, 2023

Women and the world need more physicians like Dr. Holly Thacker.

Reviewed on Jun 22, 2023

Dr Thacker is truly a gift and I am feeling so much better. I am confident with her guidance I will continue to feel even better.

Reviewed on Jun 16, 2023

Dr Thacker is a popular doctor and it's hard to get an appointment with her

Reviewed on Jun 16, 2023

Dr Thacker is a knowledgeable specialist in women's health.

Reviewed on Jun 13, 2023

Dr. Thacker's scheduler, Rhonda, is wonderful

Reviewed on Jun 5, 2023

Dr. Thacker Is most caring and compassionate doctor I have ever visited. She was thorough and extremely knowledgeable. I have no idea why I waited so long to make an appointment with her! This Is the first time I've ever been to see a doctor and felt a sense of relief when I left!

Reviewed on May 22, 2023

Always a pleasure seeing Dr Thacker. She listens to my concerns and we work together what is best for my gyn health and my bone health. I refer all my friends to her, because she is so thorough.

Reviewed on May 19, 2023

She prescribed something I didn't need.

Reviewed on May 19, 2023

She talked way too fast... Re-assessing this doctor for the future.

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