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Department Subspecialty Care for Women's Health
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English
Surgeon No
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus


Additional Locations

Specialties & Treatments

Treatment & Services

  • Bioidentical Hormone Therapy
  • Bone Density Testing
  • Breast Cancer Risk Assessment
  • Cervical Polypectomy
  • Endometrial Biopsy
  • Interdisciplinary Women's Health
  • IV Reclast Infusion For Postmenopausal Osteoporosis
  • Menopausal Risk Assessment
  • Specialty Women's Health
  • Vertebral Fracture Assessment
  • Women's Health
View all 11 Treatment & Services +

Specialty in Diseases & Conditions

  • Menopause
  • Osteopenia
  • Osteoporosis
  • Perimenopause Symptoms
  • Sexual Dysfunction
  • Sexual Hormone disorders
  • Vaginal Atrophy
View all 7 Specialties +


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About Holly L. Thacker, MD

Holly L. Thacker MD, FACP, director of the Cleveland Clinic Center for Specialized Women’s Health and Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University. She published her second women’s health book “Cleveland Clinic Guide to Menopause.”  Dr. Thacker is the Executive Director of national Speaking of Women's Health and directs the digital platform and directs CustomFit Physicals for women.

She was honored by the American Medical Women’s Association (AMWA) and the Journal of Women’s Health with the "Lila Wallis Women’s Health Award" in recognition of Dr. Thacker’s lifetime achievements, accomplishments, motivation, mentorship, energy and enthusiasm for women’s health, education, and research during the AMWA annual meeting and Women’s Health 2009: The 17th Annual Congress, in Williamsburg, VA.

In the Center for Specialized Women’s Health, we pursue leading edge and interdisciplinary therapies for women with a focus on menopausal and hormone risk assessment and therapies. We have started CustomFit Physicals for women to provide a uniquely personalized healthcare service that combines convenience and comprehensiveness in a one day visit with the service of a nurse navigator.  In addition, there are several new FDA approved pelvic floor stimulators that are available for women with urine leakage and pelvic muscle weakness as well as fecal incontinence and mild degrees of pelvic organ prolapse. These new pelvic floor stimulation devices are custom-fit and use stimulation to strengthen pelvic floor muscles and inhibit overactive bladder muscles while giving visual biofeedback and audible guidance. Precise adjustments can be made to ensure effective muscle training. Some women, who have only stress urinary leakage, and/or are 6 weeks post partum from vaginal delivery, may need simpler devices and all therapies can be done in the comfort and privacy of ones home. These devices can compliment, or in many cases be used instead of surgery or medications.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Residency - Cleveland Clinic
Internal Medicine
Cleveland, OH USA

Internship - Cleveland Clinic
Medical Internship
Cleveland, OH USA

Medical Education - University of Missouri-Kansas City School of Medicine
Kansas City, MO USA

Undergraduate - University of Missouri-Kansas City School of Medicine
Kansas City, MO USA

Professional Highlights

  • Author of the book, The Cleveland Clinic Guide to Menopause, a Cleveland Clinic Guide, © 2009
  • Author of the book, Women's Health: Your Body, Your Hormones, Your Choices, a Cleveland Clinic Guide, © 2007
  • Founder and Director of Women's Health Fellowship


  • Internal Medicine

Specialty Interests

Breast cancer risk assessment, hormone therapy, menopause and related medical problems, menstrual disorders and interdisciplinary women's health, osteoporosis, menopause, women's health, bioidentical hormone therapy, pelvic electrical stimulation device therapy for urinary leakage and female sexual dysfunction. Breast cancer risk assessment, hormone therapy, menopause and related medical problems, menstrual disorders and interdisciplinary women's health, osteoporosis, menopause and women's health

Awards & Honors

  • Healthnetwork Service Excellence Award, 2010
  • Best Doctors, Cleveland magazine, 1998, 2002, 2004, 2006-2014
  • Best Doctors in America, 1998, 2000-2002, 2007, 2008
  • Cleveland Clinic Women's Health Center Top Executive, Women's Health Services, 2007
  • Legal Resolution from Cuyahoga County Commissioners on Local and National Leadership in Women’s Health, 2006
  • Research Program of the Year. Bone Disease Program. Thacker HL et al. Recognized for multidisciplinary work. Notations newsletter of Cleveland Clinic Lerner Research Institute,, 7/21/2005
  • Who's Who in Health, Crain's Cleveland Business, 2002$0$0Distinguished Women in Health Care, first annual listing from the Visiting Nurse Association, 2000
  • Top 40 Under Age 40, Crain's Cleveland Business, 1998$0$0Achievement in Health/Medicine, Northern Ohio Live magazine, "in recognition of outstanding contributions to the quality of life in this region,” 1998


  • Ohio State Medical Association elected Councilor 2014-2016
    North American Menopause Society
Research & Publications

Research & Publications

See publications for Holly L. Thacker, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 3/3/2021, Dr. Thacker has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Consulting and/or Speaking. Dr. Thacker receives fees of $5,000 or more per year as a paid consultant, speaker or member of an advisory committee for the following companies:

  • TherapeuticsMD, Inc.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

368 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.7 out of 5
Explains 4.7
Courtesy, Respect & Concern 4.7
Patient Rating of Doctor 4.7

96 Patient Comments

Reviewed on Jun 15, 2021

Dr. Thacker is an amazing doctor! She has a wealth of knowledge and is a true asset to the Clinic.

Reviewed on Jun 14, 2021

I recommend Dr Thacker and the Cleveland Clinic to everyone I know.

Reviewed on Jun 10, 2021

Dr Thacker is a great physician. She listens, explains and tell like it is.

Reviewed on Jun 8, 2021

This was my second visit to Dr. Thacker. She did not spend a lot of time with me addressing my concerns; she spent a lot of time looking at the computer and not talking with me and listening. I was very disappointed. During my initial visit with her she did the same thing. I decided I would give her a second chance with the second visit. At the second appointment (one for this surgery) she never addressed my concerns over drug therapies and instead shoved a prescription in my hands. Additionally, for the prescription she used a vendor other than CVS, which my insurance requires. I expected more from Dr. Thacker. I am a unique individual with unique needs and I felt like she rushed the appointment and only wanted to get me in and out. I will not return to Dr. Thacker.

Reviewed on May 27, 2021

dr. thacker did an amazing job.

Reviewed on May 24, 2021

my appointment was very rushed and when I asked about examining me, was told that she doesn't do that, butt her PA did that so I received a phone call from another providers office too make an appointment this do that another time. loads of referrals, minimal solutions, just wants to get me too someone else.

Reviewed on May 20, 2021

I recommend dr Thacker to others often.

Reviewed on May 6, 2021

it took several months to see the doctor but worth the wait!

Reviewed on Apr 30, 2021

Highly recommend Dr. Thacker, very attentive and compassionate.

Reviewed on Apr 29, 2021

Dr Thacker is incredible. I just love her. She really cares for you and is thorough and very kind. She has a nice sense of humor. She always replies on my chart and has a great staff. she is my favorite doctor and has helped me very much! Too notch as always

Reviewed on Apr 23, 2021

Dr Thacker is very thorough and explains all options

Reviewed on Apr 20, 2021

I've already recommended Dr. Thacker to 2 friends after this appointment.

Reviewed on Apr 20, 2021

great dr and team

Reviewed on Apr 15, 2021

Dr. Thacker is amazing

Reviewed on Apr 9, 2021

Dr Thacker is a wonderful physician! She is soo knowledgeable on womens health. I have and will continue to recommend her services!

Reviewed on Apr 8, 2021

dr. Thacker is the best, & video appointment is easy to connect.

Reviewed on Apr 8, 2021

dr. Thacker is my favorite dr. I have ever had.

Reviewed on Apr 6, 2021

very thorough and caring doctor

Reviewed on Mar 29, 2021

I respect Dr. Thacker's knowledge of using HRT to treat menopause. I was in a lot of discomfort (it was actually debilitating)before Dr. Thacker started treating me. She also acknowledges that medications costs are high and always tries to help me find the most economical way to buy my meds.

Reviewed on Mar 25, 2021

Dr. Holly was excellent. Very thorough in discussing my concerns.

Reviewed on Mar 25, 2021

I really commend the Cleveland Clinic for having Dr. Thacker. She is the first Dr. who has been able to address my hormonal issues and offer me a viable solution. Thank you for your innovation and commitment to women's health.

Reviewed on Mar 25, 2021

I have recommended Dr. Thacker to each female i encounter.

Reviewed on Mar 11, 2021

I never felt rushed when speaking to both doctors during my visit. All my concerns were discussed as well as detailed conversation about past medical history.

Reviewed on Mar 8, 2021

Dr. Thacker is not only knowledgeable and personable, she takes time to address patient questions and concerns. She truly cares for me as a person and recommends treatment options that suit my lifestyle. It is my pleasure to be one of her patients.

Reviewed on Feb 26, 2021

so nice to have found a doctor to address my menopause concerns!

Reviewed on Feb 26, 2021

i am extremely satisfied with Dr. Thacker's knowledge and thoroughness in regards to my concerns. She addressed everything!

Reviewed on Feb 23, 2021

Nice to get Dr Thacker back.

Reviewed on Feb 23, 2021

I love it that Dr. Thacker is very sure of her treatment plan. She gives reasons for her treatments and allows time for questions. I appreciate her straight-forwardness.

Reviewed on Feb 19, 2021

Dr. Thacker is very professional, and thorough.

Reviewed on Feb 18, 2021

Dr. Holly Thacker is AMAZING! My appointment from beginning to end was informative and caring. She answered questions I didn't even know I should have had.

Reviewed on Feb 18, 2021

I have already recommended Dr. Thacker and the practice to others.

Reviewed on Feb 9, 2021

There are certain things that can only be done in person for a thorough examination. However the video doctor's visit met my needs at this time (pandemic).

Reviewed on Feb 8, 2021

I always have a wonderful experience with Dr Thacker

Reviewed on Feb 2, 2021

Dr. Thacker really takes the time to listen and has a passion for women's health. I feel safe in her hands.

Reviewed on Feb 1, 2021

Dr. Thacker is very compassionate, a great listener and gave me a few options to consider.

Reviewed on Feb 1, 2021

Love Dr Thacker. Thankful for her. She is the best!

Reviewed on Feb 1, 2021

I'm very impressed with the responsiveness of the nurse Dr Thacker has answering her My Chart messages. Rhonda is the most amazing scheduler ! Her personality is a gift that I greatly appreciate. she brings a calm to sometimes crazy situations.

Reviewed on Feb 1, 2021

Dr Thacker is a phenom ! The knowledge she has and the speed at which she shares it is unmatched. That being said, as a patient without her knowledge and skill, there is always a massive amount of information shared . I appreciate her knowledge, but I can rarely retain or even formulate an intelligent question with her rapid fire info. If it wasn't for the "visit notes" she gives at the end of my visit, I would be totally lost.

Reviewed on Jan 29, 2021

Dr. Thacker seemed much more relaxed, more conversational and less distracted than when I see her in person. I thought it was an excellent appointment

Reviewed on Jan 12, 2021

Dr Thacker is the best! She listens to my concerns and takes the time to explain all things thoroughly. I feel so confident that I am getting the best care.

Reviewed on Jan 11, 2021

Holly is a caring wonderful Doctor

Reviewed on Jan 8, 2021

In my opinion, Dr. Holly Thacker and her staff are excellent at caring for their patients. Dr. Thacker is extremely knowledgeable and I feel like she truly cares about my health issues and providing me with solutions. She provides me with the time needed to discuss my health issues and she offers solutions that work. Her staff is caring and easy to contact and they get back to me in a timely manner when I have questions or need information. I am very pleased with the care that I receive from Dr. Thacker and I would highly recommend her to anyone who needs a menopause specialist.

Reviewed on Jan 8, 2021

My experience with Dr. Holly Thacker is excellent. I am extremely happy with her care.

Reviewed on Jan 7, 2021

Dr. Thacker is a very thorough physician. She asks the appropriate questions to get to the crux of the issue. Most importantly, she is an excellent listener. In addition, although Dr. Thacker focuses on Women's Health she often takes a multi modal approach and inquires about inter-related health issues. Her care & concern for her patients is blatantly evident.

Reviewed on Jan 7, 2021

I had a wonderful experience with Dr. Thacker and Dr. Conran I look forward to returning feeling better with treatments they suggested.

Reviewed on Jan 7, 2021

I will recommend Dr. Thacker to others.

Reviewed on Dec 22, 2020

Holly Thacker is very thorough and knowledgeable. I value her as a physician.

Reviewed on Dec 21, 2020

Very good doctor but talks really fast. She could interrupt less while I'm answering questions.

Reviewed on Dec 17, 2020

Dr. Thacker and staff apologized for delay after I was in a treatment room. everyone informative and listened to my concerns.

Reviewed on Dec 15, 2020

Dr. Holly is warm, friendly, compassionate and informative.

Reviewed on Nov 30, 2020

Dr Thacker and entire staff are up to date on knowledge and very good to work with. very caring

Reviewed on Nov 17, 2020

Dr. Thacker is wonderful. She always spends the amount of time needed for you and your visit. She is very intelligent and I believe all her decisions regarding my care have been perfect. I feel like a friend to her as opposed to a casual physician. She adds her bone and nutrition website that is awesome along with providing copies and printed material in a folder to take home. She always makes sure the patient is informed! You are truly blessed to have her on your medical staff.

Reviewed on Nov 6, 2020

Dr. Holly Thacker is truly the most caring, kind, thoughtful, well informed, thorough and brilliant doctor that I have ever met!

Reviewed on Nov 6, 2020

CCF is remarkable and I am proud to be a patient of such an extraordinary health care provider.

Reviewed on Oct 30, 2020

Dr Thacker is the best healthcare provider I have ever had.

Reviewed on Oct 30, 2020

Dr Thacker is the most knowledgeable doctor for women's health that I have ever experienced. I am grateful for her expertise!

Reviewed on Oct 27, 2020

Dr Thacker is a Godsend! I have suffered for 5 years with severe vaginal atrophy. I am 49, young for the issues I was having. Dr Thacker listened and knew exactly how I was feeling- she even used the same words that I do to explain the pain. she was extremely thorough, listened and answered every question. I am SO grateful the Clinic has someone of her expertise and kindness!

Reviewed on Oct 26, 2020

I think that there should be a box about the expertise of the provider Dr Thacker would be 10 plus

Reviewed on Oct 22, 2020

Dr. Thacker was so thorough and full of resources for me.

Reviewed on Oct 22, 2020

Dr. Thacker and everyone was so thorough

Reviewed on Oct 16, 2020

Dr. Thacker is an extremely good listener and includes my thoughts in her decision making. She is a through physician is also very knowledgeable.

Reviewed on Oct 12, 2020

I learned a lot of good/helpful info. really happy I have her as my Doctor.

Reviewed on Oct 8, 2020

nurse and fellow were great. dr is not a warm fuzzy personality, I felt a little rushed through but when i voiced concern she was attentive to it. will see how the path we have chosen pans out before passing a judgement

Reviewed on Oct 8, 2020

Dr. Thacker took a lot of time with me, answered all my questions and took my concerns seriously. I feel I'm in excellent hands and fortunate to have her as a provider.

Reviewed on Oct 2, 2020

very good doctor!

Reviewed on Oct 2, 2020

Dr. Thacker was extremely knowledgeable, thorough and made me feel so at ease during my appointment. I feel the entire team was so nice and knowledgeable. I had an excellent experience.

Reviewed on Oct 2, 2020

Since I never did a virtual doctor's appointment, it was a bit stressful not knowing if I was doing the right thing. Now that I have done it once, it will be easier to do the next time.

Reviewed on Oct 1, 2020

I have recommended Dr. Thacker to friends

Reviewed on Sep 29, 2020

Dr. Thacker is wonderful.

Reviewed on Sep 17, 2020

Dr. Thacker is an outstanding doctor.

Reviewed on Sep 15, 2020

I experienced exceptional care and am grateful for the kindness and expertise that is the hallmark of Dr. Thacker and her staff.

Reviewed on Sep 11, 2020

Dr.Thacker is a wonderful doctor .she is extremely knowledgeable about all aspects of womens health . She treats you like one of her family.

Reviewed on Sep 10, 2020

Dr. Thacker and her staff, Rhonda and Lilly, are amazing! They take the time to listen and engage in discussing things.

Reviewed on Sep 10, 2020

Dr. Thacker is amazing! the depth of her knowledge just amazes me. I'm so very pleased she is my doctor.

Reviewed on Sep 10, 2020

I've been struggling with severe insomnia for better than 2 years. She is the most thorough doctor I've seen. She looked beyond CPAP to address and solve my underlying problem.

Reviewed on Aug 27, 2020

Dr. Thacker is a wonderful person and a great doctor! She is so knowledgeable when it comes to health issues concerning women!

Reviewed on Aug 27, 2020

My appointment with Dr. Thacker went better than I expected. I just had a major surgery and traveled four hours to see her. She was very understanding of my questions and agreed the VA physicians should source out women's health totally if they are not confident to continue prescriptions for menopausal women on their annual primary visit! I am very thankful for the VA and for Cleveland Clinic for taking care of me!

Reviewed on Aug 27, 2020

Thanks to Dr. Thacker and Dr. Conkle ( not sure i have her name right).

Reviewed on Aug 21, 2020

Dr Thacker added a Rx and I am already feeling much better. I love to ability to visit virtually as I am in AZ the majority of the time. thank you

Reviewed on Aug 21, 2020

Wonderful experience. The doctor visit was prompt and Dr. Thacker spent a lot of time with me and listened to my concerns. She is excellent. The office staff was also terrific and helped to schedule follow up appointments.

Reviewed on Aug 21, 2020

Dr. Holly Thacker is always very helpful. She makes you feel at ease talking about very personal subjects. She is great.

Reviewed on Aug 18, 2020

Everyone is over worked.More staff in the whole Clinic would be good.Holly Thacker is a wonderful, personable, knowledgeable physician. I'm in good hands.

Reviewed on Aug 4, 2020

Dr. Thacker is a force to be reckoned with. :) I admired her confidence and her ability to clearly articulate a plan for my health.

Reviewed on Aug 4, 2020

Rhonda in Dr. Thacker's office is terrific. She accommodated my request for an early morning appointment.

Reviewed on Aug 4, 2020

Dr. Thacker always asks questions to get to the best diagnosis.

Reviewed on Aug 4, 2020

Dr. Thacker included a Fellow. I like that. I feel like I am contributing to a physician's training & I get the advantage of another medical opinion.

Reviewed on Aug 3, 2020

best dr. for hormone balancing. great listener and forward thinking.

Reviewed on Jul 28, 2020

I'm an RN and I was extremely impressed by dr. Thackers knowledge. I feel like I finally found someone who listens, cares, and treats the issues I'm having. I'm very thankful my small hometown dr referred me to her.

Reviewed on Jul 27, 2020

I did feel a bit overwhelmed by the whole visit with the doctor. It was my first visit and the masks definitely didn't help. My doctor knew all the information about how to treat me, but I couldn't even think of questions for her because of nerves and the feeling of being overwhelmed by all the information. I almost got the feeling that I should understand everything immediately and not need to ask questions. That being said, since I was nervous, I will see her again and hope the visit goes better.

Reviewed on Jul 23, 2020

Dr. Thacker was very thorough and is an overall outstanding physician.

Reviewed on Jul 23, 2020

was exceptional good doctor and staff

Reviewed on Jul 23, 2020

the staff and doctor were professional, very knowledgeable and Dr. was extremely focused

Reviewed on Jul 21, 2020

Dr Thacker office was prompt reaching out and following up which gave me peace of mind and made me feel heard.

Reviewed on Jul 21, 2020

I love Dr Thacker and would be devasted if she retired! Ive never met or had a doctor so versed in Womens Health and so eager to share with the patient. Dr Thacker provides the information I need to make informed decisions about my health. Dr Thacker listens I feel heard and am treated as a partner in my health care. Dr Thacker knowledge experience and passion has be invaluable so I view her as a trusted health care provider.

Reviewed on Jul 16, 2020

So easy to see the doctor by getting in due to a cancellation.

Reviewed on Jul 16, 2020

I cannot emphasize enough how much I respect Dr. Thacker. She is wonderful.

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