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Department Subspecialty Care for Women's Health
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English
Surgeon No
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus


Additional Locations

Specialties & Treatments

Treatment & Services

  • Bioidentical Hormone Therapy
  • Bone Density Testing
  • Breast Cancer Risk Assessment
  • Cervical Polypectomy
  • Endometrial Biopsy
  • Interdisciplinary Women's Health
  • IV Reclast Infusion for Postmenopausal Osteoporosis
  • Menopausal Risk Assessment
  • Specialty Women's Health
  • Vertebral Fracture Assessment
  • Women's Health
View all 11 Treatment & Services +

Specialty in Diseases & Conditions

  • Menopause
  • Osteopenia
  • Osteoporosis
  • Perimenopause Symptoms
  • Sexual Dysfunction
  • Sexual Hormone Disorders
  • Vaginal Atrophy
View all 7 Specialties +


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About Holly L. Thacker, MD

Holly L. Thacker MD, FACP, director of the Cleveland Clinic Center for Specialized Women’s Health and Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University. She published her second women’s health book “Cleveland Clinic Guide to Menopause.”  Dr. Thacker is the Executive Director of national Speaking of Women's Health and directs the digital platform and directs CustomFit Physicals for women.

She was honored by the American Medical Women’s Association (AMWA) and the Journal of Women’s Health with the "Lila Wallis Women’s Health Award" in recognition of Dr. Thacker’s lifetime achievements, accomplishments, motivation, mentorship, energy and enthusiasm for women’s health, education, and research during the AMWA annual meeting and Women’s Health 2009: The 17th Annual Congress, in Williamsburg, VA.

In the Center for Specialized Women’s Health, we pursue leading edge and interdisciplinary therapies for women with a focus on menopausal and hormone risk assessment and therapies. We have started CustomFit Physicals for women to provide a uniquely personalized healthcare service that combines convenience and comprehensiveness in a one day visit with the service of a nurse navigator.  In addition, there are several new FDA approved pelvic floor stimulators that are available for women with urine leakage and pelvic muscle weakness as well as fecal incontinence and mild degrees of pelvic organ prolapse. These new pelvic floor stimulation devices are custom-fit and use stimulation to strengthen pelvic floor muscles and inhibit overactive bladder muscles while giving visual biofeedback and audible guidance. Precise adjustments can be made to ensure effective muscle training. Some women, who have only stress urinary leakage, and/or are 6 weeks post partum from vaginal delivery, may need simpler devices and all therapies can be done in the comfort and privacy of ones home. These devices can compliment, or in many cases be used instead of surgery or medications.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Residency - Cleveland Clinic
Internal Medicine
Cleveland, OH USA

Internship - Cleveland Clinic
Medical Internship
Cleveland, OH USA

Medical Education - University of Missouri-Kansas City School of Medicine
Kansas City, MO USA

Undergraduate - University of Missouri-Kansas City School of Medicine
Kansas City, MO USA

Professional Highlights

  • Author of the book, The Cleveland Clinic Guide to Menopause, a Cleveland Clinic Guide, © 2009
  • Author of the book, Women's Health: Your Body, Your Hormones, Your Choices, a Cleveland Clinic Guide, © 2007
  • Founder and Director of Women's Health Fellowship


  • Internal Medicine

Specialty Interests

Breast cancer risk assessment, hormone therapy, menopause and related medical problems, menstrual disorders and interdisciplinary women's health, osteoporosis, menopause, women's health, bioidentical hormone therapy, pelvic electrical stimulation device therapy for urinary leakage and female sexual dysfunction. Breast cancer risk assessment, hormone therapy, menopause and related medical problems, menstrual disorders and interdisciplinary women's health, osteoporosis, menopause and women's health

Awards & Honors

  • Healthnetwork Service Excellence Award, 2010
  • Best Doctors, Cleveland magazine, 1998, 2002, 2004, 2006-2014
  • Best Doctors in America, 1998, 2000-2002, 2007, 2008
  • Cleveland Clinic Women's Health Center Top Executive, Women's Health Services, 2007
  • Legal Resolution from Cuyahoga County Commissioners on Local and National Leadership in Women’s Health, 2006
  • Research Program of the Year. Bone Disease Program. Thacker HL et al. Recognized for multidisciplinary work. Notations newsletter of Cleveland Clinic Lerner Research Institute,, 7/21/2005
  • Who's Who in Health, Crain's Cleveland Business, 2002$0$0Distinguished Women in Health Care, first annual listing from the Visiting Nurse Association, 2000
  • Top 40 Under Age 40, Crain's Cleveland Business, 1998$0$0Achievement in Health/Medicine, Northern Ohio Live magazine, "in recognition of outstanding contributions to the quality of life in this region,” 1998


  • Ohio State Medical Association elected Councilor 2014-2016
  • North American Menopause Society
Research & Publications

Research & Publications

See publications for Holly L. Thacker, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 6/22/2023, Dr. Thacker has reported no financial relationship with industry that is applicable to this listing. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

334 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.7 out of 5
Explains 4.7
Courtesy, Respect & Concern 4.7
Patient Rating of Doctor 4.7

86 Patient Comments

Reviewed on Aug 22, 2023

Dr Holly Thacker is an excellent doctor. She is thorough & up to date on all new medical treatments & procedures.

Reviewed on Aug 21, 2023

Dr Thacker is an incredibly knowledgeable and compassionate physician. I am so fortunate to be her patient, and I am so grateful to receive cutting edge, world class care from Dr Thacker and her team. I highly recommend her.

Reviewed on Aug 21, 2023

Dr. Thacker is Very thorough!! Didn't feel rushed ! Answered all my questions!! Trust her opinion explicitly!!

Reviewed on Aug 11, 2023

Dr Thacker is very knowledgeable. She spoke fast and I had trouble following but she circled back for me.

Reviewed on Aug 4, 2023

Dr Holly Thacker is a fantastic doctor so happy she is helping me feel better!

Reviewed on Jul 31, 2023

Dr. Thacker is very professional and listens to all your medical concerns. She Is very knowledgeable and personable. Thank you, Dr. Thacker

Reviewed on Jul 28, 2023

I have a great amount of respect for Dr. Thacker and her efforts to help me improve my health.

Reviewed on Jul 28, 2023

Very positive experience. Doctor Thacker was very thorough.

Reviewed on Jul 27, 2023

Dr Thacker is exceptional. Her expertise and explanation was very comforting. A truly gifted physician.

Reviewed on Jul 26, 2023

Dr Thacker is amazing! Whip smart & at the forefront of women's health issues. I value her opinion in all health matters & feel blessed to have found her many years ago. At every appointment I always learn something new relative to retaining my good health. I attribute much of my well being to her guidance & more recently to that of Dr Pederson as well. Both are friends as well as respected associates & have helped me in immeasurable ways.

Reviewed on Jul 25, 2023

Love Dr. Thacker and her team!

Reviewed on Jul 21, 2023

I am so grateful to be under Dr. Holly Thacker's care. I probably wouldn't be alive today if it weren't for her. Very, very, very grateful!

Reviewed on Jul 20, 2023

Dr. Thacker is the most thorough and informative doctor I have ever seen. I have spoke highly of her and referred her to others.

Reviewed on Jul 18, 2023

Dr. Thacker and staff have always shown care and taken time to explain my condition, the options available, and it was no different this time. I would gladly recommend Dr. Thacker to others.

Reviewed on Jul 17, 2023

Cleveland Clinic and the providers are above any provider I have seen in Erie PA where I live. Respect, care and knowledge of the medical issues I have been treated for outweigh any other provider I have visited.

Reviewed on Jul 13, 2023

I can't tell you how much I appreciate her as my doctor. Dr Thacker's knowledge on woman's health is not only impeccable, she cares about her patients wellbeing.

Reviewed on Jun 29, 2023

Women and the world need more physicians like Dr. Holly Thacker.

Reviewed on Jun 22, 2023

Dr Thacker is truly a gift and I am feeling so much better. I am confident with her guidance I will continue to feel even better.

Reviewed on Jun 16, 2023

Dr Thacker is a popular doctor and it's hard to get an appointment with her

Reviewed on Jun 16, 2023

Dr Thacker is a knowledgeable specialist in women's health.

Reviewed on Jun 13, 2023

Dr. Thacker's scheduler, Rhonda, is wonderful

Reviewed on Jun 5, 2023

Dr. Thacker Is most caring and compassionate doctor I have ever visited. She was thorough and extremely knowledgeable. I have no idea why I waited so long to make an appointment with her! This Is the first time I've ever been to see a doctor and felt a sense of relief when I left!

Reviewed on May 22, 2023

Always a pleasure seeing Dr Thacker. She listens to my concerns and we work together what is best for my gyn health and my bone health. I refer all my friends to her, because she is so thorough.

Reviewed on May 19, 2023

She prescribed something I didn't need.

Reviewed on May 19, 2023

She talked way too fast... Re-assessing this doctor for the future.

Reviewed on Apr 28, 2023

Dr Thacker provided excellent care. She listened, offered recommendations, and seemed to care about my well being.

Reviewed on Apr 20, 2023

Dr Thacker is a tremendous physician and I recommend her any chance I get!

Reviewed on Apr 13, 2023

I have raved about Dr. Thacker for years. She is the most thorough doctor I have ever seen.

Reviewed on Apr 10, 2023

I was very impressed by Dr Thacker's knowledge, experience, care and friendliness

Reviewed on Apr 6, 2023

Dr. Thacker is the best doctor I have ever seen. I credit her with saving my life when no other doctors could help me.

Reviewed on Apr 6, 2023

I traveled from from Carolina to see Dr. Thacker, as always she was informative and left me assured that my treatment was the correct one. She takes the time to inform you of the right treatments and medicines to achieve your best health. I"ll travel again to see her anytime.

Reviewed on Apr 3, 2023

I had a very good experience with Dr. Holly Thacker and I plan to return in a few months.

Reviewed on Mar 31, 2023

Dr Thacker is extremely knowledgeable, understanding, listens well, provides solutions for all of my issues, and is easy to communicate with. She is on top of everything in her field and obviously keeps learning about new things on the horizon. I feel very privileged to be one of her patients.

Reviewed on Mar 31, 2023

Dr Thacker took the time to review my tests and put together a plan of care with my input

Reviewed on Mar 31, 2023

I really trust and respect Dr Thacker

Reviewed on Mar 31, 2023

Dr. Thacker is amazing. I'm so grateful to have her as my physician.

Reviewed on Mar 30, 2023

Dr Thacker was wonderful and listened to all of my concerns and came to with a plan. She was great at explaining everything as well. I highly recommend her and have already!

Reviewed on Mar 24, 2023

Dr Thacker shows great interest and concern for all areas of my health. It is overwhelming to consider the different options available to treat osteoporosis and I am thankful that Dr Thacker has the indepth knowledge and concern to help me navigate the best option that I can be the most comfortable with.

Reviewed on Mar 24, 2023

Dr. Thacker needs to slow down and explain things better. She talks too fast and tells you to listen to her podcasts. I'm not pay her to listen to her podcast. I'm paying her to listen and treat.

Reviewed on Mar 20, 2023

Dr Thacker, dana and Rhonda are all wonderful. They really.listen to concerns and have created a warm and open environment !

Reviewed on Mar 20, 2023

The appointment was VERY rushed. She was running one hour behind. It felt that she used my appointment to attempt to catch up.

Reviewed on Mar 17, 2023

I couldn't ask for better care than what I received from Dr. Thacker

Reviewed on Mar 17, 2023

Dr.Thacker is one of the best doctors in your clinic. She knows so much about women's health issues. So glad she is at the clinic.

Reviewed on Mar 13, 2023

The doctor worked very rapidly which was good on one hand but not clear with the medications prescribed. I might have missed the info because she talked and typed so fast.

Reviewed on Mar 10, 2023

Staff was helpful. The Dr.personally walked me over to the blood lab. Everyone there was friendly and attentive.

Reviewed on Feb 28, 2023

Doctor tends to talk quickly, not explaining herself very well.

Reviewed on Feb 27, 2023

Provider was curt, dismissive, arrogant. I have tolerated similar behavior In past in exchange for her knowledge and expertise. No more - I will be establishing care with a different provider.

Reviewed on Feb 24, 2023

I love Dr Thacker! Been seeing her for over 10 years! She always listens to my needs.

Reviewed on Feb 24, 2023

Dr. Thacker is an amazing doctor and I continue to have the utmost trust in her for my care. Unfortunately, during this visit I felt that she was rushed and did not take the time I have come to expect from her. She seemed to be going through things very quickly and, at times, it was hard for me to even follow what she was saying. I am confident it was a bad day and not indicative of the care I have always received from her in the past but I felt it was important to share the feedback.

Reviewed on Feb 23, 2023

Dr. Thacker is very thorough and professional. She puts her patients first. I am lucky to have her as my doctor.

Reviewed on Feb 23, 2023

Again, Doctor Thacker is an outstanding physician.Thank you CCF for providing me such a outstanding physician.

Reviewed on Feb 23, 2023

Dr. Thacker is amazing!

Reviewed on Feb 17, 2023

Great experience. Dr. Thacker is very thorough and follows through with support.

Reviewed on Feb 16, 2023

Very sharp! Dr.Thacker gives valuable information and advice.

Reviewed on Feb 13, 2023

Very rushed appointment after a long wait. I'm sure she is amazing and in demand. I look forward to a better experience next time.

Reviewed on Feb 7, 2023

Dr Thacker is very knowledgeable and she brought some orders in my chart to my attention that I'd previously been unaware of

Reviewed on Jan 27, 2023

Dr. Thacker is very caring and thorough. I appreciate the questions she asked about my history and symptoms. She is a wealth of information. She advocates for women and is so knowledgeable about the unique health needs of women.

Reviewed on Jan 26, 2023

It was a very good experience Dr Thacker has help in the area of my health goals

Reviewed on Jan 20, 2023

Everything is great. Dr. Thacker is amazing.

Reviewed on Jan 20, 2023

Dr Thacker has greatly improved the quality of my life. She is always gracious and I appreciate the care and attention she has given me.

Reviewed on Jan 20, 2023

Dr. Thacker is a dedicated and brilliant practitioner.

Reviewed on Jan 19, 2023

I cannot speak highly enough of Dr. Thacker. I am beyond grateful to have her as my doctor and managing my care.

Reviewed on Jan 19, 2023

The above responses pertain to the physician (she may have referred to herself as a fellow'. She was very professional, yet friendly and helpful. At the end of the visit I saw Dr Thacker for a few minutes. I have a great regard for her knowledge. She's pretty amazing, although a little gruff. That won't stop me from continuing as her patient, though. She's helped me by prescribing hormone replacement therapy patches and keeping me apprised of how I can best manage my health at my age. I'm quite grateful for that.

Reviewed on Jan 17, 2023

Dr.Thacker is an exceptional doctor. The whole staff is excellent. This is the future for Cleveland Clinic.

Reviewed on Jan 17, 2023

Provider is overpowering- very strong

Reviewed on Jan 12, 2023

Dr. Thacker is always willing to discuss options. She is extremely knowledgeable and I have referred several people to her for their menopause concerns.

Reviewed on Jan 10, 2023

Best office visit I ever had - doctors were fantastic- informative- read my records - really knew me as a patient - explained everything

Reviewed on Jan 9, 2023

I am fortunate to have Dr Thatcher as my gynecologist she is very knowledgeable and progressive in her treatment.

Reviewed on Jan 9, 2023

Dr. Thacker goes above and beyond to help you with your concerns. She's so knowledgeable and teaches you about your body and what to do to optimize your health.

Reviewed on Jan 3, 2023

Dr. Thacker listened to me, and now, a little over 2 weeks later, I feel human again!!!!

Reviewed on Dec 20, 2022

*Dr. Thacker and staff are a "well oiled machine" and clearly have created a positive work environment.

Reviewed on Dec 20, 2022

I am continuously grateful for Dr. Thacker's knowledge and skills.

Reviewed on Dec 15, 2022

Great physician who specializes in women's care

Reviewed on Dec 13, 2022

I have been going to Dr Thacker for about 7 years. She typically is abrupt but at this visit her manner bordered on rude. I almost felt bullied and left feeling angry. Her response to several of my questions was "go to my website" and "do some research." Her treatment plan over the years has improved my osteoporosis but her "bedside manner", especially at this most recent visit, was inappropriate.

Reviewed on Nov 21, 2022

I am the luckiest girl to have found Dr. Thacker. She has singlehandedly and rapidly taken charge of my failing health as a midlife woman, and turned the ship around. I will be forever indebted to her.

Reviewed on Nov 18, 2022

Dr. Thacker is very engaging and is always up to speed on my issues and provides excellent care when needed. Her staff is very friendly and happy to help.

Reviewed on Nov 15, 2022

Spent more time with the computer she did asked me a lot of questions but didn't really include me in the decisions that were made

Reviewed on Nov 10, 2022

Love holly Thacker! She listens and hears!

Reviewed on Nov 4, 2022

An excellent, knowledgeable doctor who helps women with issues that most physicians do not acknowledge or care about

Reviewed on Nov 1, 2022

Very good doctor, caring and kind

Reviewed on Nov 1, 2022

It is very pleasant to talk to Dr. Thacker

Reviewed on Oct 24, 2022

Dr. Thacker gave me EXCELLENT care.

Reviewed on Oct 6, 2022

Really appreciated Dr Thackers expertise, honesty, directness and recommendations!

Reviewed on Oct 4, 2022

Dr. Thacker was very rushed. I did not even get to my questions and concerns, She was very brief and seemed agitated.

Reviewed on Sep 22, 2022

Dr. Thacker is very straightforward and I like that! She talks about the evidence of her recommendations which reassures me

Reviewed on Sep 20, 2022

Dr. Holly Thacker is an excellent caregiver, extraordinary wealth of information, very kind and patient. She conveys compassion and concern, providing important feedback on progress.

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