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Department Subspecialty Care for Women's Health
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English
Surgeon No
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus


Additional Locations

Specialties & Treatments

Treatment & Services

  • Bioidentical Hormone Therapy
  • Bone Density Testing
  • Breast Cancer Risk Assessment
  • Cervical Polypectomy
  • Endometrial Biopsy
  • Interdisciplinary Women's Health
  • IV Reclast Infusion For Postmenopausal Osteoporosis
  • Menopausal Risk Assessment
  • Specialty Women's Health
  • Vertebral Fracture Assessment
  • Women's Health
View all 11 Treatment & Services +

Specialty in Diseases & Conditions

  • Menopause
  • Osteopenia
  • Osteoporosis
  • Perimenopause Symptoms
  • Sexual Dysfunction
  • Sexual Hormone disorders
  • Vaginal Atrophy
View all 7 Specialties +


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About Holly L. Thacker, MD

Holly L. Thacker MD, FACP, director of the Cleveland Clinic Center for Specialized Women’s Health and Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University. She published her second women’s health book “Cleveland Clinic Guide to Menopause.”  Dr. Thacker is the Executive Director of national Speaking of Women's Health and directs the digital platform and directs CustomFit Physicals for women.

She was honored by the American Medical Women’s Association (AMWA) and the Journal of Women’s Health with the "Lila Wallis Women’s Health Award" in recognition of Dr. Thacker’s lifetime achievements, accomplishments, motivation, mentorship, energy and enthusiasm for women’s health, education, and research during the AMWA annual meeting and Women’s Health 2009: The 17th Annual Congress, in Williamsburg, VA.

In the Center for Specialized Women’s Health, we pursue leading edge and interdisciplinary therapies for women with a focus on menopausal and hormone risk assessment and therapies. We have started CustomFit Physicals for women to provide a uniquely personalized healthcare service that combines convenience and comprehensiveness in a one day visit with the service of a nurse navigator.  In addition, there are several new FDA approved pelvic floor stimulators that are available for women with urine leakage and pelvic muscle weakness as well as fecal incontinence and mild degrees of pelvic organ prolapse. These new pelvic floor stimulation devices are custom-fit and use stimulation to strengthen pelvic floor muscles and inhibit overactive bladder muscles while giving visual biofeedback and audible guidance. Precise adjustments can be made to ensure effective muscle training. Some women, who have only stress urinary leakage, and/or are 6 weeks post partum from vaginal delivery, may need simpler devices and all therapies can be done in the comfort and privacy of ones home. These devices can compliment, or in many cases be used instead of surgery or medications.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Residency - Cleveland Clinic
Internal Medicine
Cleveland, OH USA

Internship - Cleveland Clinic
Medical Internship
Cleveland, OH USA

Medical Education - University of Missouri-Kansas City School of Medicine
Kansas City, MO USA

Undergraduate - University of Missouri-Kansas City School of Medicine
Kansas City, MO USA

Professional Highlights

  • Author of the book, The Cleveland Clinic Guide to Menopause, a Cleveland Clinic Guide, © 2009
  • Author of the book, Women's Health: Your Body, Your Hormones, Your Choices, a Cleveland Clinic Guide, © 2007
  • Founder and Director of Women's Health Fellowship


  • Internal Medicine

Specialty Interests

Breast cancer risk assessment, hormone therapy, menopause and related medical problems, menstrual disorders and interdisciplinary women's health, osteoporosis, menopause, women's health, bioidentical hormone therapy, pelvic electrical stimulation device therapy for urinary leakage and female sexual dysfunction. Breast cancer risk assessment, hormone therapy, menopause and related medical problems, menstrual disorders and interdisciplinary women's health, osteoporosis, menopause and women's health

Awards & Honors

  • Healthnetwork Service Excellence Award, 2010
  • Best Doctors, Cleveland magazine, 1998, 2002, 2004, 2006-2014
  • Best Doctors in America, 1998, 2000-2002, 2007, 2008
  • Cleveland Clinic Women's Health Center Top Executive, Women's Health Services, 2007
  • Legal Resolution from Cuyahoga County Commissioners on Local and National Leadership in Women’s Health, 2006
  • Research Program of the Year. Bone Disease Program. Thacker HL et al. Recognized for multidisciplinary work. Notations newsletter of Cleveland Clinic Lerner Research Institute,, 7/21/2005
  • Who's Who in Health, Crain's Cleveland Business, 2002$0$0Distinguished Women in Health Care, first annual listing from the Visiting Nurse Association, 2000
  • Top 40 Under Age 40, Crain's Cleveland Business, 1998$0$0Achievement in Health/Medicine, Northern Ohio Live magazine, "in recognition of outstanding contributions to the quality of life in this region,” 1998


  • Ohio State Medical Association elected Councilor 2014-2016
  • North American Menopause Society
Research & Publications

Research & Publications

See publications for Holly L. Thacker, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 3/3/2021, Dr. Thacker has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Consulting and/or Speaking. Dr. Thacker receives fees of $5,000 or more per year as a paid consultant, speaker or member of an advisory committee for the following companies:

  • TherapeuticsMD, Inc.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

361 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.7 out of 5
Explains 4.6
Courtesy, Respect & Concern 4.7
Patient Rating of Doctor 4.7

89 Patient Comments

Reviewed on Oct 11, 2021

I went in because I was confused about continuing medications or not. Please tell Dr Thacker that the information she shared with me was very helpful, she took away my worries, and she has made my life better. I plan to have follow-ups with telehealth.

Reviewed on Oct 7, 2021

Rhonda, who schedules for Dr. Thacker is exceptional. She huddled the patients' schedules with multiple CCF appointmentsAnd makes it seem easy. She is polite, caring and always smiling.

Reviewed on Oct 7, 2021

All physicians should aspire to practice like Dr. Thacker. She has prevented and stopped a negative clinical outcome for me. She is a great listener, explains things well, and then jumps into action. She monitored me along the way. And I am in awe of how thorough she is.

Reviewed on Oct 7, 2021

Awesome doctor and staff in their office

Reviewed on Oct 4, 2021

Dr. Thacker is an excellent Doctor. I really trust her as a professional.

Reviewed on Sep 28, 2021

Dr Thacker took so much time with me and explained her concerns. Very kind and compassionate

Reviewed on Sep 23, 2021

Love this doctor

Reviewed on Sep 23, 2021

Dr. Thacker was very relaxed, listened and provided feedback, insight and information. She helped more with Hashimoto's than my internist and endocrinologist ever have.

Reviewed on Sep 17, 2021

Could not connect virtually with Dr. Thacker. Not her fault though. Service late in the day? We both tried, but she ended up calling me back after we lost the connection.

Reviewed on Sep 16, 2021

Both Doctors were kind and thorough, it was refreshing that they took the time needed to help with my symptoms and diagnosis. They came highly recommended and did not disappoint

Reviewed on Sep 13, 2021

Always a good experience at my appointment with dr Thaker her nurse and Rhonda for scheduling

Reviewed on Sep 9, 2021

Dr Thacker and her Fellow Dr Cochran were amazing. They inquired about my health in great detail, heard me accurately and gave me wonderfully helpful information. I cannot overstate my satisfaction and the hope for a better healthier future from their care and caring.

Reviewed on Sep 9, 2021

Miss Rhonda who does Dr. Thacker's scheduling is wonderful to deal with.

Reviewed on Sep 9, 2021

Dr. Thacker has literally changed my life. I feel healthier than I have in years. She takes a very detailed approach and insures you get the necessary care you require, even of it is provided by another physician. I recommend her Custom Fit program to every pre/menopausal woman I know.

Reviewed on Sep 7, 2021

Best Dr in whole universe. Very professional and caring.

Reviewed on Sep 7, 2021

I have no problem contacting Dr. Thacker's office with making appointments or questions.

Reviewed on Sep 7, 2021

Dr. Thacker is very good at what she does and I trust her judgment and expertise in her field.

Reviewed on Aug 20, 2021

Dr. Holly Thacker has been terrific.

Reviewed on Aug 13, 2021

Dr. Thacker has been my doctor for more than 20 yrs. She is excellent!

Reviewed on Aug 10, 2021

Thorough, listens, compassionate, great doctor.

Reviewed on Aug 6, 2021

Dr. Thacker provided me with a very comprehensive treatment plan and explained everything in terms I could understand. She provided me with helpful suggestions and I felt that she cared about me as a person. I trust her expertise and am extremely happy I found her.

Reviewed on Aug 6, 2021

Dr. Thacker is a wonderful physician. Very thorough.

Reviewed on Aug 5, 2021

Dr Thacker goes out of her way to accommodate my visits and gives me the best options for best care!

Reviewed on Aug 5, 2021

Rhonda in Dr. Thacker is as courteous and professional as they come

Reviewed on Aug 5, 2021

Dr. Thacker is excellent and so very engaged and helpful

Reviewed on Aug 5, 2021

Both physicians, the Fellow and Dr. Thacker, were extremely professional and helpful. They took their time listening to my needs, asking many questions and focused only on what would be helpful to me. I feel I have a physician that takes care of my total medical wellbeing.

Reviewed on Aug 3, 2021

Dr. Thacker is an excellent doctor I would highly recommend her to anyone.

Reviewed on Jul 27, 2021

I was told Thatcher was booked at the time I was going to be there for other treatment . To my surprise Julie called and said she was able to get me in ! All went great . Dr Thatcher thought I needed to see a doctor about my Para Thyroid and was able to get that appointment for me while I was there too! It was a seamless experience . Dr Thatcher was able to put all the pieces of the puzzle together . I do have 1 question about the hormone patch she wrote the prescription for me ! Dr Thatcher took lots of time with me . The nurse, and the lady that gets appointments for you were great too!!!!!

Reviewed on Jul 23, 2021

I learned at my appointment that blood tests I received last summer ('20) showed that I might be using too much of one hormone treatment. Nobody told me then. Only now did Dr. Thacker suggest I cut back a little on the use of the hormone. She mentioned that over-use can have negative effects. If so, why was I not told to cut back use of the hormone a year ago?

Reviewed on Jul 22, 2021

Dr. Thacker is the most competent physician I have ever interacted with regarding my healthcare.

Reviewed on Jul 16, 2021

Dr. Thacker is caring and supportive. She provides education and offers encouragement in making changes that will make a difference.

Reviewed on Jul 16, 2021

Awesome doctor

Reviewed on Jul 15, 2021

Dr. Thacker listened to all my concerns and was very compassionate.

Reviewed on Jul 8, 2021

Dr. Thacker is very knowledgeable and passionate about her field. I felt she was very thorough and was genuinely concerned about my health and well being. I was a little overwhelmed at first, and I did tell her that, as she gave me a lot of info fast, but once I came home and read what was in the folder carefully, I felt better about and understood what she was telling me. I was taken aback when I first was asked to sign up for her website and given info about products to purchase, but I do think she wanted me to have as much info as I could to help me. I have looked at the website and will do so again.

Reviewed on Jul 8, 2021

Dr Thacker diagnosed me and sent in a prescription before she even met me or I had done any blood work. She assumed I was much farther along into menopause than I actually am. When the blood work came back, she had to pull the prescriptions, as they were not appropriate.

Reviewed on Jul 8, 2021

I never felt so insulted by a physician as I did with Dr. Thacker. She made me feel as if I was a non compliant patient. She kept rattling off values from prior tests. She wouldn't let me speak and explain . I do not think I would ever come back to see her. It was a horrible experience.

Reviewed on Jul 6, 2021

I really appreciate a care.provider that actually spends time with me and explaining my course of treatment. Dr. Thacker shows she is concerned with my well being.

Reviewed on Jul 6, 2021

Outstanding service in all respects, both medical and administrative. Dr Thacker's attention to every detail is impressive. Her nurse Lillie is another gift. This was my first visit, but both Dr Thacker and Lillie worked with me as if they already knew me. Also, lab results were posted before my plane back to New Orleans boarded! I'm not accustomed to such efficiency!

Reviewed on Jul 1, 2021

I saw her twice for the same problem. Both times I thought I'd get an internal exam to rule out infection or cancer. The second time I came she told me she does not do internals and told me to try Dr Batur.I feel like I wasted my time and why doesn't she do internals? She's a gynecologist? It cost me time and money to come there.

Reviewed on Jun 29, 2021

Dr Thacker is always very informative. She has a wealth of knowledge as it pertains to women's health! If only there were more female doctors committed to women's health. She always takes time to listen. I have been completely happy with her care.

Reviewed on Jun 29, 2021

I love that I can schedule multiple appointments in the same day, it's very convenient as I drive an hour and 20 minutes to main campus. I get bone density, mammogram, blood work and see the doctor in the same day! Thank you for going above with the ease of scheduling.

Reviewed on Jun 28, 2021

I was at this appt for a lump I fiound in my right breast. The NP checked my right and left breast. She told me it felt like cyst.She set me up for a mammogram and ultra sound. No available appt till July 26. I was scared to wait that long, but nothing was done to get a appt sooner. Met with Dr. Thacker that same day, she showed no interest in getting testing any sooner. Very upsetting for me. She was more concerned about a bone density test.

Reviewed on Jun 25, 2021

love Dr Thacker

Reviewed on Jun 15, 2021

Dr. Thacker is an amazing doctor! She has a wealth of knowledge and is a true asset to the Clinic.

Reviewed on Jun 14, 2021

I recommend Dr Thacker and the Cleveland Clinic to everyone I know.

Reviewed on Jun 10, 2021

Dr Thacker is a great physician. She listens, explains and tell like it is.

Reviewed on Jun 8, 2021

This was my second visit to Dr. Thacker. She did not spend a lot of time with me addressing my concerns; she spent a lot of time looking at the computer and not talking with me and listening. I was very disappointed. During my initial visit with her she did the same thing. I decided I would give her a second chance with the second visit. At the second appointment (one for this surgery) she never addressed my concerns over drug therapies and instead shoved a prescription in my hands. Additionally, for the prescription she used a vendor other than CVS, which my insurance requires. I expected more from Dr. Thacker. I am a unique individual with unique needs and I felt like she rushed the appointment and only wanted to get me in and out. I will not return to Dr. Thacker.

Reviewed on May 27, 2021

dr. thacker did an amazing job.

Reviewed on May 24, 2021

my appointment was very rushed and when I asked about examining me, was told that she doesn't do that, butt her PA did that so I received a phone call from another providers office too make an appointment this do that another time. loads of referrals, minimal solutions, just wants to get me too someone else.

Reviewed on May 20, 2021

I recommend dr Thacker to others often.

Reviewed on May 6, 2021

it took several months to see the doctor but worth the wait!

Reviewed on Apr 30, 2021

Highly recommend Dr. Thacker, very attentive and compassionate.

Reviewed on Apr 29, 2021

Dr Thacker is incredible. I just love her. She really cares for you and is thorough and very kind. She has a nice sense of humor. She always replies on my chart and has a great staff. she is my favorite doctor and has helped me very much! Too notch as always

Reviewed on Apr 23, 2021

Dr Thacker is very thorough and explains all options

Reviewed on Apr 20, 2021

I've already recommended Dr. Thacker to 2 friends after this appointment.

Reviewed on Apr 20, 2021

great dr and team

Reviewed on Apr 15, 2021

Dr. Thacker is amazing

Reviewed on Apr 9, 2021

Dr Thacker is a wonderful physician! She is soo knowledgeable on womens health. I have and will continue to recommend her services!

Reviewed on Apr 8, 2021

dr. Thacker is the best, & video appointment is easy to connect.

Reviewed on Apr 8, 2021

dr. Thacker is my favorite dr. I have ever had.

Reviewed on Apr 6, 2021

very thorough and caring doctor

Reviewed on Mar 29, 2021

I respect Dr. Thacker's knowledge of using HRT to treat menopause. I was in a lot of discomfort (it was actually debilitating)before Dr. Thacker started treating me. She also acknowledges that medications costs are high and always tries to help me find the most economical way to buy my meds.

Reviewed on Mar 25, 2021

Dr. Holly was excellent. Very thorough in discussing my concerns.

Reviewed on Mar 25, 2021

I really commend the Cleveland Clinic for having Dr. Thacker. She is the first Dr. who has been able to address my hormonal issues and offer me a viable solution. Thank you for your innovation and commitment to women's health.

Reviewed on Mar 25, 2021

I have recommended Dr. Thacker to each female i encounter.

Reviewed on Mar 11, 2021

I never felt rushed when speaking to both doctors during my visit. All my concerns were discussed as well as detailed conversation about past medical history.

Reviewed on Mar 8, 2021

Dr. Thacker is not only knowledgeable and personable, she takes time to address patient questions and concerns. She truly cares for me as a person and recommends treatment options that suit my lifestyle. It is my pleasure to be one of her patients.

Reviewed on Feb 26, 2021

so nice to have found a doctor to address my menopause concerns!

Reviewed on Feb 26, 2021

i am extremely satisfied with Dr. Thacker's knowledge and thoroughness in regards to my concerns. She addressed everything!

Reviewed on Feb 23, 2021

Nice to get Dr Thacker back.

Reviewed on Feb 23, 2021

I love it that Dr. Thacker is very sure of her treatment plan. She gives reasons for her treatments and allows time for questions. I appreciate her straight-forwardness.

Reviewed on Feb 19, 2021

Dr. Thacker is very professional, and thorough.

Reviewed on Feb 18, 2021

Dr. Holly Thacker is AMAZING! My appointment from beginning to end was informative and caring. She answered questions I didn't even know I should have had.

Reviewed on Feb 18, 2021

I have already recommended Dr. Thacker and the practice to others.

Reviewed on Feb 9, 2021

There are certain things that can only be done in person for a thorough examination. However the video doctor's visit met my needs at this time (pandemic).

Reviewed on Feb 8, 2021

I always have a wonderful experience with Dr Thacker

Reviewed on Feb 2, 2021

Dr. Thacker really takes the time to listen and has a passion for women's health. I feel safe in her hands.

Reviewed on Feb 1, 2021

Dr. Thacker is very compassionate, a great listener and gave me a few options to consider.

Reviewed on Feb 1, 2021

Love Dr Thacker. Thankful for her. She is the best!

Reviewed on Feb 1, 2021

I'm very impressed with the responsiveness of the nurse Dr Thacker has answering her My Chart messages. Rhonda is the most amazing scheduler ! Her personality is a gift that I greatly appreciate. she brings a calm to sometimes crazy situations.

Reviewed on Feb 1, 2021

Dr Thacker is a phenom ! The knowledge she has and the speed at which she shares it is unmatched. That being said, as a patient without her knowledge and skill, there is always a massive amount of information shared . I appreciate her knowledge, but I can rarely retain or even formulate an intelligent question with her rapid fire info. If it wasn't for the "visit notes" she gives at the end of my visit, I would be totally lost.

Reviewed on Jan 29, 2021

Dr. Thacker seemed much more relaxed, more conversational and less distracted than when I see her in person. I thought it was an excellent appointment

Reviewed on Jan 12, 2021

Dr Thacker is the best! She listens to my concerns and takes the time to explain all things thoroughly. I feel so confident that I am getting the best care.

Reviewed on Jan 11, 2021

Holly is a caring wonderful Doctor

Reviewed on Jan 8, 2021

In my opinion, Dr. Holly Thacker and her staff are excellent at caring for their patients. Dr. Thacker is extremely knowledgeable and I feel like she truly cares about my health issues and providing me with solutions. She provides me with the time needed to discuss my health issues and she offers solutions that work. Her staff is caring and easy to contact and they get back to me in a timely manner when I have questions or need information. I am very pleased with the care that I receive from Dr. Thacker and I would highly recommend her to anyone who needs a menopause specialist.

Reviewed on Jan 8, 2021

My experience with Dr. Holly Thacker is excellent. I am extremely happy with her care.

Reviewed on Jan 7, 2021

Dr. Thacker is a very thorough physician. She asks the appropriate questions to get to the crux of the issue. Most importantly, she is an excellent listener. In addition, although Dr. Thacker focuses on Women's Health she often takes a multi modal approach and inquires about inter-related health issues. Her care & concern for her patients is blatantly evident.

Reviewed on Jan 7, 2021

I had a wonderful experience with Dr. Thacker and Dr. Conran I look forward to returning feeling better with treatments they suggested.

Reviewed on Jan 7, 2021

I will recommend Dr. Thacker to others.

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