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Amanda Vest, MBBS

Amanda Vest, MBBS
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Department Cardiovascular Medicine
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English
Surgeon No


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About Amanda Vest, MBBS

Amanda Vest, MBBS, MPH, FHFSA, FAHA, FACC, is Section Head of Heart Failure and Transplantation Cardiology in The Tomsich Family Department of Cardiovascular Medicine, Miller Family Heart, Vascular & Thoracic Institute. She sees patients at Main Campus.

Specialty Interests: Heart failure with reduced ejection fraction (HFrEF), heart failure with preserved ejection fraction (HFpEF), cardiomyopathy, sarcoidosis, cardiogenic shock, obesity, cardiac cachexia.

Experience: Dr. Vest has extensive experience in helping patients with heart failure manage their condition in ways that improve their quality of life with a focus on diet and nutrition. She is a fellow of the Heart Failure Society of America, American Heart Association and American College of Cardiology and an author of the 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure. She is also a Diplomate of the American Board of Obesity Medicine.

Success Rates: Cleveland Clinic Heart, Vascular & Thoracic Institute is nationally and internationally renowned for the world’s best cardiovascular care, drawing patients from across the country and around the world. To learn about patient outcomes for specific conditions and procedures at Cleveland Clinic, go to: https://my.clevelandclinic.org/departments/heart/outcomes/358-institute-summary

Education: Dr. Vest received her medical degree from Imperial College School of Medicine, London, United Kingdom, graduating with Distinction. She also holds a master’s degree in public health from the Harvard TH Chan School of Public Health, Boston. She completed her internal medicine residency at Boston University Medical Center, Boston, with an additional year as Chief Resident. She came to Cleveland Clinic following her residency for a three-year fellowship in cardiovascular medicine and completed her training at Cleveland Clinic as a fellow in advanced heart failure and cardiac transplantation.

Prior to her 2024 appointment to the Cleveland Clinic medical staff, Dr. Vest wasthe medical director of the Cardiac Transplantation Program at Tufts Medical Center, Boston, a position she held since 2018. She co-directed the Clinical Nutritional course at Tufts University School of Medicine.

Research, Publications and Speaking: Dr. Vest is a dedicated physician-researcher with a primary research focus on nutrition and metabolism in patients with heart failure (HF). She has established a Nutrition-Heart Failure research program studying the relationships between obesity and HF, and mechanisms of the muscle wasting that characterizes cardiac cachexia.

Her research has demonstrated that left ventricular assist devices (LVADs) can improve the metabolic dysfunction seen in patients with advanced HF, and that improvements in metabolism are associated with increased survival. Her work also demonstrates that patients who receive an LVAD tend to gain muscle mass in the first few months of device support. Her current clinical trial is investigating whether a dietary protein supplement can also reverse skeletal muscle wasting. Her ultimate research goal is to develop nutritional and metabolic therapies that improve both body composition and survival in patients with HF.

Dr. Vest’s research funding has included grants from the American Heart Association, National Institutes of Health Heart Lung and Blood Institute and Center for Advancing Translational Sciences. She has published extensively on her research in notable peer-reviewed medical journals, including Circulation, Circulation: Heart Failure, and Journal of the American College of Cardiology: Heart Failure, and currently serves on the editorial boards of two journals.

She also has coauthored review articles and editorials in leading cardiology journals and more than a dozen chapters in cardiology and HF textbooks. She frequently is an invited presenter at major medical meetings, scientific sessions and podcasts, speaking on obesity and nutrition in patients with HF, cardiac cachexia, and innovations in heart transplantation and HF therapies.

Leisure Activities: Outside of work, Dr. Vest enjoys swimming, weightlifting, and traveling.

About Dr. Vest: “I have always been interested in the science of heart-pumping function and find it rewarding to clinically participate in a field where we can make such a difference to patients’ lives. I feel fortunate that my career as a heart failure cardiologist has coincided with so much exciting innovation in the medications, devices and transplant technologies that we can offer to our patients.”

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Graduate School - Harvard School of Public Health/Harvard University
Public Health / Concentration in Clinical Effectiveness
Boston, MA United States

Fellowship - Cleveland Clinic
Advanced Heart Failure and Transplant Cardiology
Cleveland, OH United States

Fellowship - Cleveland Clinic
Cardiovascular Disease
Cleveland, OH United States

Residency - Boston University / Boston University Medical Center
Internal Medicine
Boston, MA United States

Internship - Chelsea and Westminster Hospital
6 months Medicine, 6 months General Surgery
London, United Kingdom

Medical Education - Imperial College London Faculty of Medicine
Medicine MBBS with intercalated BSc
London, United Kingdom


  • Internal Medicine - Advanced Heart Failure and Transplant Cardiology
  • Obesity Medicine - Internal Medicine
  • Internal Medicine
  • Internal Medicine - Cardiovascular Disease

Awards & Honors

  • 2024 Top Reviewer for 2023, Circulation: Heart Failure
  • 2023 Outstanding Reviewer, Circulation
  • 2023 Teacher of the Year Award, Cardiology Fellowship Program, Tufts Medical Center
  • 2022 Outstanding Reviewer, Circulation 2022
  • 2022 Outstanding Lecturer and Outstanding Small Group Instructor, Tufts University School of Medicine
  • 2021 - 2023 Chair, Heart Failure Society of America International Relations Committee
  • 2020 - 2021 Accepted to the Clinical Trials Research Course, American College of Cardiology
  • 2021 Women in Medicine and Science Mentorship Seed Award, Tufts Medical Center Physicians Organization
  • 2019 - 2022 Task Force Co-Chair, ISHLT/HFSA Statement on Acute Mechanical Circulatory Support
  • 2019 Beals Goodfellow Research Prize, CardioVascular Research Institute, Tufts Medical Center
  • 2017 - 2019 Chair, HFSA Consensus Statement on Nutrition, Obesity and Cachexia in Patients with HF
  • 2018 Transplant Registry Early Career Award, ISHLT
  • 2016, 2017 Outstanding Teacher Award, Cardiology Fellowship Program, Tufts Medical Center
  • 2015 Attending Teaching Award, Medicine Residency Program, Tufts Medical Center
  • 2014 Excellence in Teaching Award, Cleveland Clinic
  • 2013 Tomsich Award for Excellence in Research, Cardiovascular Medicine Fellowship, Cleveland Clinic
  • 2013 Razavi Award for Clinical Excellence, Cardiovascular Medicine Fellowship, Cleveland Clinic
  • 2012 MPH Tuition Award, Robert and Suzanne Tomsich Chair, Cardiovascular Medicine Fellowship, Cleveland Clinic
  • 2012 Women in Cardiology Trainee Award for Excellence, American Heart Association
  • 2011 CICU Fellow of the Year, Cardiovascular Medicine Fellowship, Cleveland Clinic
Research & Publications

Research & Publications

See publications for Amanda Vest, MBBS.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 7/2/2024, Dr. Vest has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

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