Pasquale Santangeli, MD, PhD
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View All PlansAbout Pasquale Santangeli, MD, PhD
Specialty Interests: Catheter ablation, ventricular tachycardia (VT), ventricular fibrillation, premature ventricular complexes, atrial fibrillation (AF), atrial flutter, supraventricular tachycardia, arrhythmogenic right ventricular cardiomyopathy, Brugada syndrome, left atrial appendage closure, Wolff-Parkinson-White syndrome (WPW), biventricular pacemaker (CRT), implantable cardioverter defibrillator (ICD)
Experience: The Cardiac Electrophysiology and Pacing Section offers a range of highly specialized approaches to diagnose and treat patients with heart rhythm problems (arrhythmia). The Section’s specialists annually perform nearly 6,000 procedures in the Electrophysiology Lab, including pacemaker and defibrillator implantations, ablations of various types of arrhythmias and cardioversions.
Success Rates: Cleveland Clinic is nationally and internationally renowned for the world’s best cardiovascular care, drawing patients from across the country and around the world. To learn about patient outcomes for specific conditions and procedures at Cleveland Clinic, go to http://my.clevelandclinic.org/heart/about-heart-vascular-institute/treatment-outcomes.aspx
Education: Dr. Santangeli holds a doctorate in medicine from Catholic University of the Sacred Heart, Rome, Italy, and a doctorate in medical and epidemiological sciences from the University of Foggia, Foggia, Italy. After completing his studies, he remained at Catholic University for his cardiovascular diseases fellowship.
Dr. Santangeli began his subspecialty training as a research fellow in cardiac electrophysiology at Texas Cardiac Arrhythmia Institute, St. David’s Medical Center, Austin, Texas. He continued his training with two fellowships in clinical cardiac electrophysiology, first at Stanford University School of Medicine, Stanford, Calif., and finishing at Hospital of the University of Pennsylvania, Philadelphia.
Prior to joining the Cleveland Clinic medical staff in 2022, Dr. Santangeli was a staff electrophysiologist, associate professor of medicine, director of the Catheter Ablation Research Program, co-director of the Penn Ventricular Tachycardia Center of Excellence and director of EP Innovation and Clinical Research at Hospital of the University of Pennsylvania.
Research, Publications and Speaking: Dr. Santangeli has served as principal investigator for clinical studies to determine the efficacy and improve safety of catheter ablation of atrial fibrillation (AF) and ventricular tachycardia (VT).
Dr. Santangeli has coauthored more than 500 research papers, abstracts, editorials, review papers and case reports published in leading medical journals. He has editorial responsibilities with a number of prestigious journals, including Circulation: Arrhythmia and Electrophysiology, Heart Rhythm Journal and JACC: Clinical Electrophysiology and also has coauthored more than a dozen chapters for electrophysiology textbooks. He is a frequent invited lecturer and presenter at medical meetings in the United States and internationally, speaking on all aspects of catheter ablation of cardiac rhythm disorders.
An innovator in his field, Dr. Santangeli has developed several new techniques and technologies for treating AF and VT, typically in patients with complicated arrhythmias or challenging anatomy.
About Dr. Santangeli: “It is a privilege to serve patients with cardiac arrhythmia disorders, and my greatest reward is to solve their arrhythmia problems and restore quality of life. I am committed to delivering excellent clinical outcomes through compassionate, evidence-based and innovative care.”
Leisure Activities: In his leisure time, Dr. Santangeli enjoys travel, nature, hiking and spending time with family.
Education & Professional Highlights
Appointed
2022
Education & Fellowships
Medical Education - University of Foggia
Foggia, Puglia,
Italy
2016
Fellowship - Hospital of the University of Pennsylvania
Cardiac Electrophysiology
Philadelphia,
PA United States
2014
Fellowship - Stanford School of Medicine
Cardiac Electrophysiology
Stanford,
CA
2013
Fellowship - Texas Cardiac Arrhythmia Institute
Austin,
TX United States
2012
Medical Education - Catholic University of Sacred Heart
Rome,
Italy
2006
Awards & Honors
- 2022 : Abstract finalist, Mark E. Josephson Abstract Competition & VT Innovation Award, VT Symposium 2022, New York
2020 : First Mid-Atlantic Medical Awards recipient, Philadelphia
2018 : Knight of the Order of Merit of the Italian Republic
2014, 2015 : Best Reviewer, Annals of Internal Medicine
2014 : Best Fellow-in-Training Abstract Award, American College of Cardiology Scientific Session, Washington, DC
2013 : Early-Career Best Poster Award, American Heart Association Scientific Session, Dallas
2012 : Best Paper Award, European Cardiac Arrhythmia Society Congress, Munich
Best Paper Award, World Society of Arrhythmias Congress, Athens
2011 : Best Oral Abstract Presentation Award, Best Poster Abstract Presentation Award, CardioRhythm 2011, Hong Kong
Research & Publications
See publications for Pasquale Santangeli, MD, PhD.
(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)
Industry Relationships
Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.
To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.
As of 9/19/2024, Dr. Santangeli has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.
Consulting and/or Speaking. Dr. Santangeli receives fees of $5,000 or more per year (or, in rare cases, equity or stock options) as a paid consultant, speaker or as a member of an advisory committee for the following companies:
- Boston Scientific Corporation
- Biotronik, Inc.
- Medical Device Business Services, Inc., formerly Depuy, Inc.
- Abbott Laboratories
Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.
* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.
245 Patient Satisfaction Reviews
The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.
Responses are measured on a scale of 1 to 5 with 5 being the best score.
The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.
| Overall | Star Ratings | |
|---|---|---|
| Explains | 4.9 | |
| Courtesy, Respect & Concern | 4.9 | |
| Patient Rating of Doctor | 4.9 |
41 Patient Comments
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Reviewed on Apr 9, 2025
Dr. Santangeli is such a breath of fresh air.
Reviewed on Apr 7, 2025
I think it is important to spend quality time with each patient. The more patients you get and need to take care of it makes it harder to give them quality time. Though the doctor does such a good job answering questions and is very knowledgeable and helpful. I'm grateful for his skill and input concerning my situation. He made me feel at ease.
Reviewed on Apr 7, 2025
Dr Santangeli is a marvel
Reviewed on Mar 12, 2025
Video call w Dr. Santangelli was easy and efficient. Good system!
Reviewed on Mar 12, 2025
Dr. Santangelli is the best!
Reviewed on Feb 26, 2025
Excellent Doctor, friendly and knowledgeable. I need a heart ablation and he's book up for 7 month, that's the only problem.
Reviewed on Feb 24, 2025
I was very impressed with the process of requesting an appointment. I was particularly appreciative of how quickly I was able to schedule an appointment with Dr Santangeli
Reviewed on Feb 24, 2025
Dr Santangeli spent time discussing my situation and thoroughly describing best course of action at this time. I truly appreciated his time , expertise, and personalized attention to my medical history and to me as an individual.
Reviewed on Feb 17, 2025
My doctor was amazing. For being so skilled, he showed a lot of compassion. I highly recommend him
Reviewed on Jan 29, 2025
Great doctor
Reviewed on Jan 6, 2025
The doctor was thorough with reviewing my history and providing me with recommendations. He was clearly and without medical jargon explain the best treatment plan for me. It was certainly worth my drive to Cleveland!
Reviewed on Dec 4, 2024
Very pleased with Dr. Santangelli in every regard
Reviewed on Dec 2, 2024
Dr was great.
Reviewed on Nov 25, 2024
I am very well pleased with the clinic and the doctor. Courtesy is the strongest point that I received. Glad I came in and saw the doctor I did.
Reviewed on Nov 20, 2024
Dr. Santangeli's expertise and commitment are truly exceptional. I feel very fortunate to have benefitted from his expertise during the recent procedure.
Reviewed on Nov 20, 2024
Dr. Santangeli and his staff are very talented and dedicated professionals. I feel very fortunate to have had a chance to benefit from his skills during the recent procedure. On the other hand, I sense that the patient workload at the clinic has increased substantially over the past decade which has impacted the individual care and attention that has been evident during past visits.
Reviewed on Nov 4, 2024
Visit with Dr was very professional and pleasantHe explained the Procedure in detail
Reviewed on Oct 28, 2024
I believe Dr. Santangeli is probably the finest doctor I have ever worked with. When I go to the Cleveland Clinic and visit with Dr. Santangeli,I'am confident I'am receiving the bet possible care and advice. I feel very lucky to have met and deal with Dr. Santangeli.
Reviewed on Oct 28, 2024
I travel from the Buffalo N.Y.area. I have friends with the same heart condition as mine, and would like to meet Dr. Santangeli for help.
Reviewed on Oct 28, 2024
Cery difficult to get an timely appointment with doctors. Schedulers are very polite but there not much they have control over,
Reviewed on Oct 23, 2024
Date was OK for me (thank goodness!), but there was no choice. I understand, because the doc is very busy and does good work!
Reviewed on Oct 14, 2024
Once we got called in for the Doctor appointment everything moved quickly and great. I appreciate the explanations for future considerations, tests and follow up actions by Dr. Santangeli.
Reviewed on Sep 30, 2024
I asked many, many questions of this top-notich professional Dr. S. He understood all of my concerns, and advised that I had been doing well caring for this involved heart issue. I felt very comfortable with him and with my own efforts! His concurrence was very important to me!
Reviewed on Sep 30, 2024
Glad to have established as my Doctor going forward.
Reviewed on Sep 11, 2024
Top notch physician
Reviewed on Sep 11, 2024
Thank you very very much Dr. Santangeli Pasquale you are apart of our family And thank you for your prompt support , care compassion and friendly and comprehensive care of treatment
Reviewed on Sep 11, 2024
Dr. S is amazing. He saved my life .
Reviewed on Aug 28, 2024
Clinic is booked out months ahead. Possibly could use more staff, physicians, advocates to help reduce appointment scheduling wait time. I had a great experience with my doctor and his assistants. This clinic is very well organized for patient support and time efficiency, once you're in the system, on day of appointment.
Reviewed on Aug 28, 2024
Dr. Santangeli was very professional and enabled me to understand well about my condition and recommended procedures. He was also very personable and friendly, which made me feel more confident and relaxed about my circumstances. His schedule is very full for several months, but he recommended options for doing something during the interim to help improve my condition.
Reviewed on Jul 15, 2024
Dr. Santangeli is a phenomenal physician who takes the time to understand patient concerns, and has the ability to address them.
Reviewed on Jun 24, 2024
Have already recommended provider to others.
Reviewed on Jun 10, 2024
I had an excellent evperiance with all my health providers at CC
Reviewed on Jun 5, 2024
I have a great deal of confidence in my physician's ability. The brevity of the consult made it difficult to develop rapport. The six to seven month wait time before my procedure was distressing.
Reviewed on May 20, 2024
The doctor was very friendly and down to earth.
Reviewed on May 8, 2024
Dr Santangeli is amazing!
Reviewed on Apr 29, 2024
Dr. Santangeli is the best !
Reviewed on Apr 29, 2024
Dr Santangeli was even more helpful and attuned to my situation than we had expected.
Reviewed on Apr 29, 2024
First time a doctor actually listened to me and looked at my information as a medical professional myself
Reviewed on Apr 29, 2024
Dr. Santangeli, is a great doctor that cares about his patients, He is a doctor that has a plan and knows what he wants to do, and also has a backup plan. His explanation of what procedure he too was very good and made me feel like I was relaxed and knowledgeable of my procedures.
Reviewed on Apr 29, 2024
I can't speak highly enough about my experiences at Cleveland clinic and Dr Santangeli and his staff. I rave about it to everyone who will listen and recommend Cleveland Clinic as tops in the field.
Reviewed on Apr 29, 2024
Dr Santangeli is a blessing. I am so thankful for the care he has provided me and forever grateful for all he has done to help me. Please let him know..