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Department Orthopaedic Surgery
Primary Location Euclid Hospital
Type of Doctor Adults Only
Languages English
Surgeon Yes
Locations Specialties & Treatments

Treatment & Services

  • Anterior approach total hip replacement
  • Anterior Total Hip Replacement
  • Arthritic Knee Conditions
  • Arthritis, Surgical And Non Surgical Treatment
  • Arthroplasty
  • Hip & Knee Surgery
  • Hip Replacement
  • Hip Revision
  • Hyaluronic acid injections
  • Joint Aspiration
  • Joint Injections
  • Joint Reconstruction
  • Joint Replacement
  • Joint Replacement Of The Knee
  • Knee Arthroplasty
  • Knee Joint Disorders
  • Knee Pain
  • Knee Replacement
  • Knee Revision
  • Minimally Invasive Hip Joint Replacement
  • Outpatient Knee Replacement
  • Partial Knee Replacement
  • Peripheral Joint Injections
  • Primary And Revision Joint Replacements
  • Primary And Revision Total Hip Arthroplasty
  • Primary And Revision Total Knee Arthroplasty
  • Reconstructive Surgery Of The Hip
  • Reconstructive Surgery Of The Knee
  • Revision Total Hip Replacement
  • Revision Total Knee Replacement
  • Robotic Assisted Knee Replacement
  • Robotic Assisted Partial Knee Replacement
View all 32 Treatment & Services +

Specialty in Diseases & Conditions

  • Arthritic Knee Problems
  • Arthritis
  • Arthritis Of The Hip
  • Arthritis Of The Knee
  • Avascular Necrosis Of The Hip
  • Avascular Necrosis Of The Knee
  • Hip Dysplasia
  • Hip Instability
  • Hip Osteoarthritis
  • Hip Pain
  • Joint Disorders
  • Knee Arthritis
View all 12 Specialties +


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About Matthew Deren, MD

Matthew Deren, MD is a board-certified orthopaedic surgeon in the Division of Adult Reconstruction. He specializes in knee and hip replacement surgeries, including direct anterior total hip replacement, robotic-assisted total and partial knee replacements, as well as complex and revision knee and hip replacements. He sees patients at Euclid Hospital and Main Campus. 

Dr. Deren completed his undergraduate studies at Yale University, followed by medical school at the Alpert Medical School of Brown University. He then continued his training with orthopaedic residency at Brown University and Rhode Island Hospital where he received the Haffenreifer Housestaff Excellence Award as one of the best chief residents in the entire medical system. He then completed an orthopaedic trauma fellowship at Brown University and Rhode Island Hospital, followed by a fellowship in Adult Reconstruction at the Cleveland Clinic in 2018. In 2022, Dr. Deren returned to the Cleveland Clinic as a Staff Orthopaedic Surgeon after practicing at the University of Massachusetts School of Medicine. In his free time, he enjoys fishing, hunting, woodworking, and spending time with his family. 

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Cleveland Clinic
Adult Reconstructive Surgery
Cleveland, OH USA

Fellowship - Rhode Island Hospital
Orthopaedic Trauma
Providence, RI USA

Residency - Rhode Island Hospital
Orthopaedic Surgery
Providence, RI USA

Medical Education - Brown University
Providence, RI USA


  • Orthopaedic Surgery

Awards & Honors

  • Distinguished Teacher of the Year Award, University of Massachusetts Orthopedic Surgery Residency Program, 2021
  • Haffenreifer Housestaff Excellence Award, Rhode Island Hospital, 2016
Research & Publications

Research & Publications

See publications for Matthew Deren, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 9/1/2022, Dr. Deren has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Consulting and/or Speaking. Dr. Deren receives fees of $5,000 or more per year as a paid consultant, speaker or member of an advisory committee for the following companies:

  • Expert Review, Inc.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

35 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.8 out of 5
Explains 4.8
Listens 5
Courtesy, Respect & Concern 4.8
Patient Rating of Doctor 4.8

3 Patient Comments

Reviewed on Jan 18, 2023

Dr. Deren answered my questions, and showed care and concern for me. Instilled confidence in him, and my ability to undergo hip surgery.

Reviewed on Jan 12, 2023

Doctor Deren was very thorough in his explanation of what is ahead in my treatment. He answered all our questions and was very caring!

Reviewed on Dec 7, 2022

Dr Deren was excellent in showing and explaining to me what my over 2 year old problem was/is. He took his time, I didn't feel rushed and he answered every question I had and then some. I would recommend him over any orthopedic surgeon I have ever come in contact with. Just wish I had him in both my last (2020) hip replacements.

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