alert icon Coronavirus

Now scheduling COVID-19 vaccines for ages 5+, boosters and third doses
Schedule your appointment
COVID-19 vaccine FAQs

Going to a Cleveland Clinic location?
We will not be scheduling non-urgent inpatient surgeries at many Ohio hospitals through Jan. 3, 2022
New visitation guidelines
Masks required for patients and visitors (even if you're vaccinated)

Department Internal Medicine and Geriatrics
Primary Location Independence Family Health Center
Type of Doctor Adults Only
Languages English
Surgeon No


Is Cleveland Clinic Part of Your Insurance?

Review a list of accepted insurance plans for our Northeast Ohio locations or learn more about purchasing a contracted managed care plan.

View All Plans

About Leslie DiRuzza, DO

Dr. Leslie DiRuzza D.O. is an internal medicine trained physician working in outpatient primary care at the Cleveland Clinic Independence Family Health Center. She received her undergraduate degree in biology/premedicine from the Ohio State University in Columbus, Ohio in 2010. Completed her medical education at Lake Erie College of Osteopathic Medicine in Erie, Pennsylvania. She graduated with a Doctorate of Osteopathic Medicine in 2014. Attended internal medicine internship and residency at Allegheny General Hospital in Pittsburgh, Pennsylvania. She graduated from the program in spring 2017. Shortly after she joined the Cleveland Clinic Foundation as part of Community Internal Medicine in August of 2017. Since that time, she has had a clinical focus of primary care with an interest in resident education. She has also been a member of the American College of Physicians (ACP) since 2017 and attends their yearly meetings for continuing medical education. Dr DiRuzza has also been newly appointment in October 2021 as Associate Section Head of the Independence practice. 

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Residency - Allegheny General Hospital
Internal Medicine
Pittsburgh, PA USA

Medical Education - Lake Erie College of Osteopathic Medicine
Bradenton, FL USA

Undergraduate - Ohio State University
Columbus, OH USA


  • Internal Medicine
Research & Publications

Research & Publications

See publications for Leslie DiRuzza, DO.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 10/25/2021, Dr. DiRuzza has reported no financial relationship with industry that is applicable to this listing. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

56 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.9 out of 5
Explains 4.9
Courtesy, Respect & Concern 4.9
Patient Rating of Doctor 4.9

7 Patient Comments

Reviewed on Oct 21, 2021

Dr Diruzza is very professional, but also caring. She listens easily, and helps me to coordinate my medical priorities and care.

Reviewed on Sep 9, 2021

Overall visit with Doctor went well. She said s an excellent listener and provides me with all the knowledge I need to make me comfortable in understanding.

Reviewed on Apr 2, 2021

The doctor gives plenty of time to address patients questions,concerns and decisions. She provides a comfortable environment and reassures the patient of questions or confusion as she provides thoughal explanation.

Reviewed on Feb 23, 2021

Dr. DiRizza was wonderful. I've had some negative experiences with practioners in the past. She was kind, personable, and listened.

Reviewed on Feb 16, 2021

Had some difficulty getting an appointment with a new doctor due to the pandemic. My doctor had retired.

Reviewed on Feb 16, 2021

This was my first visit with Dr. Diruzza and she was just wonderful!

Reviewed on Feb 9, 2021

Dr. Diruzza is a big asset to your medical team and I consider myself fortunate to have her as my provider

Related Videos Featuring Leslie DiRuzza, DO

Related Videos Featuring Leslie DiRuzza, DO

Back to Top