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Department Gastroenterology, Hepatology & Nutrition
Primary Location North Ohio Gastroenterology
Type of Doctor Adults Only
Languages Arabic, English
Surgeon No
Locations Specialties & Treatments

Treatment & Services

  • Colonoscopy
  • Egd
  • Endoscopic Retrograde Cholangiopancreatography
  • Endoscopic Ultrasound
  • Flexible Sigmoidoscopy
View all 5 Treatment & Services +

Specialty in Diseases & Conditions

  • Bile Duct Diseases
  • Colon Polyps
  • Gastroesophageal Reflux (GERD)
  • General Gastroenterological Disorders
  • Hepatitis C
  • Pancreatic Disease
View all 6 Specialties +


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Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - MetroHealth Medical Center
Cleveland, OH USA

Residency - MetroHealth Medical Center
Internal Medicine
Cleveland, OH USA

Internship - MetroHealth Medical Center
Internal Medicine
Cleveland, OH USA

Medical Education - Aleppo University Faculty of Medicine


  • Internal Medicine
  • Internal Medicine - Gastroenterology
Research & Publications

Research & Publications

See publications for Khaled Issa, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 12/14/2020, Dr. Issa has reported no financial relationship with industry that is applicable to this listing. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

274 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.9 out of 5
Explains 4.9
Courtesy, Respect & Concern 5
Patient Rating of Doctor 5

67 Patient Comments

Reviewed on Oct 20, 2021

It was a very good experience. It was my first time meeting Doctor Issa. I think explained very well what the cyst in my pancreas looked like and what my options are.

Reviewed on Oct 20, 2021

Excellent doctor!

Reviewed on Oct 18, 2021

I have always had a good experience with Dr. Issa, he is a wonderful doctor.

Reviewed on Oct 12, 2021

Dr. Issa impressed me as a very caring physician. It was very easy to talk with him. He was pleasant, and looked me in the eyes.He was NOT paying more attention to the computer screen than to what I was saying. Dr. Issa is an asset to the Clinic.

Reviewed on Oct 11, 2021

Friendly staff. Dr issa is the best.

Reviewed on Oct 6, 2021

He is one of the best doctors I have ever seen! Concerned about my condition, concerned about my recuperation, concerned about any possible future events. Listens! Actually ask questions and waits for a response. Considers the response, and has a solution. He's very easy to talk to. He does not make you feel inferior. He and his staff are on top of any medication that needs to be refilled.

Reviewed on Oct 6, 2021

I've recommended several of my doctors to family and friends.

Reviewed on Oct 1, 2021

Dr Issa always seems to be on top of things regarding my health

Reviewed on Oct 1, 2021

Dr. Issa was responsive informative and prompt. Outstanding physician and staff. Couldnt ask for better care.

Reviewed on Sep 28, 2021

Dr. Issa was wonderful and very kind and listened fully to all my questions and concerns

Reviewed on Sep 27, 2021

Dr. Issa was the best. Very concerned and caring. I cannot express in words how wonderful and compassionate he was.

Reviewed on Sep 15, 2021

Dr. Issa was wonderful, he saw me on his 1/2 day off, he listened to me, never rushed or in a hurry. He seemed concerned about my symptoms, very kindly wanted to have the MRI done at a Cleveland Clinic facility closer to me, so I wouldn't have to drive all the way to Westlake, more convenient for me. Never had a Dr. Be so considerate before. I felt like he really cared about me. I have had this health problem for several years and he wants to fix' it.

Reviewed on Sep 15, 2021

Although he was running behind schedule, Dr. Issa took his time (as he always does) to go through test results, provide care, discuss recommendations and answer all questions.

Reviewed on Sep 15, 2021

Dr. Issa is one of the most caring,friendly,efficient physicians I have ever met. He is warm in his demeanor,and looks at you when speaking,[instead of the computer]His warmth and genuine friendliness was much appreciated!!

Reviewed on Sep 1, 2021

Dr. Has excellent rapport with patient.

Reviewed on Sep 1, 2021

While having to discuss bowel habits & issues is rather personal & having to schedule an EGD & colonscopy. *Dr. Issa made me very comfortable.

Reviewed on Aug 30, 2021

Have already recommended family to Dr Issa

Reviewed on Aug 30, 2021

Dr Issa is very skilled and very professional. He put me at ease immediately.

Reviewed on Aug 18, 2021

I showed up 15 minutes early for my appointment! Another person came late and said they got lost finding the place and was taken right away! I waited a hour before I saw the doctor! Then once we discussed the prognosis! I was scheduled for a endoscopic appointment over a month later! Then to see if a operation will be necessary I realize Dr. ISSA is a fine and well respected doctor and in demand! It seems like a long time to wait and solve my problem and hopefully nothing will arise in the mean time!

Reviewed on Aug 16, 2021

Dr. Issa is one of the most caring, compassionate doctor's I have ever encountered. He cares not only about the issue at hand but also about your fears and comfort during the procedure.

Reviewed on Jul 28, 2021

Dr. Issa was fantastic. He was attentive and extremely knowledgeable. He immediately gave you a sense of comfort and took his time to make sure you understood everything. He was on time and very prompt. Nursing staff was also excellent and very personable. Front desk staff were helpful and friendly. Great experience all around

Reviewed on Jul 27, 2021

Dr. Issa is a gem. Identified problems that were missed by previous doctor. I feel thoroughly examined and treated for all polyps identified.

Reviewed on Jul 26, 2021

Dr. K. Issa Is the best!

Reviewed on Jul 26, 2021

Staff and doctor were polite, communicated clearly, efficient and professional

Reviewed on Jul 21, 2021

It was my first visit with Dr. Issa and I felt very comfortable with him and he made me feel at east.

Reviewed on Jul 21, 2021

Dr. Issa is by far one of the BEST physicians you have on staff. His care and concern for patients and his staff that I witnessed is excellent. My wife has gone to him for several years and sent me and other family members to him. It is refreshing to know you still have caring doctors out there!

Reviewed on Jul 14, 2021

Dr. Issa is a professional who has a clear view of patient care. He is an excellent communicator, is highly intelligent, and is a pleasure to work with as a patient.

Reviewed on Jun 30, 2021

Dr. Issa is awesome

Reviewed on Jun 29, 2021

All of the staff are so nice I have never had a bad experience I love all the nurses and Dr ISSA is the best doctor ever

Reviewed on Jun 29, 2021

Dr ISSA is my favorite doctor

Reviewed on Jun 23, 2021

Dr Issa was so took all the time I needed kind answersed all my questions

Reviewed on Jun 23, 2021

Had a very good evacuation with Dr Issa. He explained everything and answered all my questions. I felt very comfortable with him. The staff was very friendly and helpful.

Reviewed on Jun 21, 2021

I'm so happy to finally have a great doctor who goes after the issues instead of just trying to treat the symptoms

Reviewed on Jun 21, 2021

My doctors in the past we're too busy to listen. While Dr. Issa IS a busy man, I still feel like he's been listening right from the start. My wife and I noticed it at the first appointment and ever since.

Reviewed on Jun 18, 2021

Dr ISSA and staff were all professional and kind.

Reviewed on May 25, 2021

Dr. Issa is amazing

Reviewed on May 25, 2021

This was my first procedure by Dr. Issa. I felt very confident in his expert care.

Reviewed on May 24, 2021

Dr Issa is the best and Dawn is very helpful.

Reviewed on Apr 23, 2021

Dr Issa personally called me to ask about symptoms, personal and family history, and to give me a quick appointment.

Reviewed on Apr 21, 2021

was very impressed with this Doctor and his staff!!

Reviewed on Apr 21, 2021

Wonderful doctor and staff!

Reviewed on Apr 13, 2021

excellent staff and Doctor

Reviewed on Apr 2, 2021

Dr. Issa was great as usual.

Reviewed on Mar 22, 2021

very caring doctor and staff

Reviewed on Mar 19, 2021

awesome Doctor and staff

Reviewed on Mar 15, 2021

I have had appointments with Dr. Issa in the past he is an excellent doctor and an asset to the Cleveland Clinic foundation. His staff is caring personable and knowledgeable.

Reviewed on Mar 15, 2021

Dr. Issa is a warm caring and knowledgeable physician. He really cares about his patients. And listens intently. Answers all my questions, fears and concerns.

Reviewed on Mar 15, 2021

very smooth surge super professional team thank you Dr.Issa I'm thankful to be one of your Patient

Reviewed on Feb 22, 2021

Overall great staff and a great doctor.

Reviewed on Feb 22, 2021

Great doctor and friend!!

Reviewed on Feb 1, 2021

Fabulous staff and physician

Reviewed on Jan 27, 2021

Dr Issa was very kind, and understanding!This is exactly why I requested to see him for my mother, he treated my Father 16 yrs ago and still as professional now as 16 yrs ago.

Reviewed on Jan 13, 2021

Dr Issa is caring, compassionate and simply an amazing physician and person!! I feel blessed to have him on my side

Reviewed on Jan 11, 2021

the entire staff is plasant, comforting and efficient. Dr. Issa is an outstanding professional.

Reviewed on Jan 11, 2021

Dr. Isa is the best!

Reviewed on Dec 30, 2020

dr Issa's staff is very courteous and attentive

Reviewed on Dec 23, 2020

excellent Doctor & Staff

Reviewed on Dec 23, 2020

Dr. Issa was courteous, informative, knowledgeable, and professional. He helped solve my health issue without any complications. Special thanks to him and to his team.

Reviewed on Dec 23, 2020

Very highly recommend Dr.Issa and his practice.

Reviewed on Dec 23, 2020

Dr. Issa is highly professional, caring, and smart. I am completely confident of his care.

Reviewed on Dec 21, 2020

Dr. Issa is amazing

Reviewed on Dec 14, 2020

Dr. Issa and his staff are just wonderful, understanding, courteous and professional.

Reviewed on Dec 14, 2020

I highly recommend Dr. Issa to anyone needing a gastroenterologist. I have been his patient since 2002 and have been pleased with hism and his care.

Reviewed on Dec 8, 2020

loved having dealt with this doctor

Reviewed on Dec 8, 2020

I absolutely love Dr Issa and his nurse Dawne they are always there for me kind compassionate and professional - very knowledgeable in their skills! May god bless them and keep them safe Mrs. Kathleen A Williams

Reviewed on Dec 4, 2020

Dr. Issa is very professional and congenial. the facility is clean and the staff friendly and reassuring.

Reviewed on Dec 1, 2020

I had Dr. Khaled Issa, for years now! He is the best! He always is so kind and friendly with me! He has always been very attentive to all I've had to tell him, and has treated me well!! He is an excellent Dr. in my view! He is very caring of how you are!! I feel like he is my friend as well as my doctor!!

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