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Department Gastroenterology, Hepatology & Nutrition
Primary Location North Ohio Gastroenterology
Type of Doctor Adults Only
Languages Arabic, English
Surgeon No
Locations Specialties & Treatments

Treatment & Services

  • Colonoscopy
  • Egd
  • Endoscopic Retrograde Cholangiopancreatography
  • Endoscopic Ultrasound
  • Flexible Sigmoidoscopy
View all 5 Treatment & Services +

Specialty in Diseases & Conditions

  • Bile Duct Diseases
  • Colon Polyps
  • Gastroesophageal Reflux (GERD)
  • General Gastroenterological Disorders
  • Hepatitis C
  • Pancreatic Disease
View all 6 Specialties +


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Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - MetroHealth Medical Center
Cleveland, OH USA

Residency - MetroHealth Medical Center
Internal Medicine
Cleveland, OH USA

Internship - MetroHealth Medical Center
Internal Medicine
Cleveland, OH USA

Medical Education - Aleppo University Faculty of Medicine


  • Internal Medicine
  • Internal Medicine - Gastroenterology
Research & Publications

Research & Publications

See publications for Khaled Issa, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 10/14/2022, Dr. Issa has reported no financial relationship with industry that is applicable to this listing. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

266 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.9 out of 5
Explains 4.9
Courtesy, Respect & Concern 4.9
Patient Rating of Doctor 4.9

54 Patient Comments

Reviewed on Dec 14, 2022

Dr. Issa is very caring & patient during appt.Always answers all my questions.

Reviewed on Dec 7, 2022

I trust Dr. Issa with my life and feel comfortable and confident enough to trust thar Dr Issa and his Team will always have my best interest and well being at heart. His team was courteous, kind and professional. I would recommend them to my friends and family as I have in the past.

Reviewed on Dec 7, 2022

Dr Issa is the best doctor ever. Thoughtful, thorough, caring, kind and supportive .

Reviewed on Nov 30, 2022

A great experience with Dr Issa and his team ( Dawn )

Reviewed on Nov 7, 2022

Excellent doc and staff

Reviewed on Nov 1, 2022

I truly value *Dr. Issa & the care he & his team provide. *Dr. Issa listens to me & I feel as though he hears me when I'm in his care.

Reviewed on Nov 1, 2022

I will definitely recommend this physician & team.

Reviewed on Oct 31, 2022

Dr.Issa and his staff always make the best of an uncomfortable procedure.

Reviewed on Oct 19, 2022

Dr. Issa was very personable and placed me at ease immediately. He voiced understanding of my GI concerns and outlined his recommended treatment plan and the rationale for this plan.

Reviewed on Oct 18, 2022

Dr. Issa is the best

Reviewed on Oct 12, 2022

Dr. Issa is the best! Listens and pays attention. Great doctor.

Reviewed on Oct 4, 2022

Dr Issa and the team in the GI Endoscopy suite, were perfect.

Reviewed on Oct 3, 2022

Very good experience and very good staff. Dr Issa is a very good physician and I myself highly recommend him for anyone who's searching for a GI specialist.

Reviewed on Sep 28, 2022

Dr. Issa and his nurse assistant Dawn, have been a godsend to me in managing my disease. I made the switch from a private practice to Dr. Issa last year and have been and continue to be very pleased with the management of care.

Reviewed on Sep 26, 2022

Doctor and his assistants were very informative as to procedure and what I could expect afterwards.

Reviewed on Sep 14, 2022

I really like that Dr Issa is very detailed and listens to your concerns then explains in great detail!Dr Issa is a great doctor!

Reviewed on Sep 12, 2022

Dr. Issa followed up after my endoscopy stating that the scarring related to healing from the liquid steroid I took prevented the procedure to complete. I have scheduled an x-ray with a liquid being taken to hopefully complete the process.

Reviewed on Sep 7, 2022

Unbelievably Efficient Appointment From The Time I Entered To The Time I Left. Took The Time To Listen To Me. From Front Desk To The Assistant To Dr. Issa To The End. An Absolutely PERFECT & EFFICIENT Process.

Reviewed on Sep 7, 2022

Great Doctor!!

Reviewed on Sep 7, 2022

This Doctor is fantastic. Patient friendly, very informative!

Reviewed on Sep 6, 2022

I am pleased that Dr. Issa continues to be in my insurance carrier's network.

Reviewed on Aug 25, 2022

Dr Issa and all the nurses and Dr Kim anesthesiologist were very caring and wonderful!

Reviewed on Aug 25, 2022

No bad experience Dr. ISSA is a wonderful , compassionate Dr who cares what his patients are going through!

Reviewed on Aug 23, 2022

Everything about procedure and Dr and his staff

Reviewed on Aug 3, 2022

Dr Issa was great

Reviewed on Aug 1, 2022

Prior to Dr Issa, I had a female gastroenterologist and was worried about having a male since she retired, BUT, I will recommend Dr Issa to everyone. He is very caring and kind as well as his staff!!! I feel safe with him and his staff as my doctor!

Reviewed on Jul 22, 2022

Very good on every level. Dr. Khaled Issa is truly an excellent doctor as well as an excellent person. He was kind, compassionate and real. I highly recommend him to everyone. The staff complimented his high standards. Dr. Essa should give lessons to the rest of the Clinic on how to treat people. He is what gives the Cleveland Clinic their great reputation. Please let him know how my family and I feel about him. I have already passed his number to ten people.

Reviewed on Jul 15, 2022

My colonoscopy from beginning to end was great! The entire staff and Dr. Issa made the whole procedure very comfortable and simple. I cannot express in words how absolutely attentive, organized and kind each person that provided my care in preparation for my colonoscopy was! Dr. Issa was, as always, very comforting, kind, professional and the very best at his job!

Reviewed on Jun 30, 2022

Dr Issa and his team are amazing. He made us feel very comfortable and confident that everything was going to be OK. He is very caring and kind and calmed our fears. Dr. Issa is amazing.

Reviewed on Jun 29, 2022

I have been a patient of Dr Issa since before he joined the Cleveland Clinic. I was pleased when he joined the Cleveland Clinic so Clinic providers can see more information to help care for me.

Reviewed on Jun 15, 2022

Finally a doctor that has my best interest in mind. A breath of fresh air dealing with dr Issa.

Reviewed on Jun 15, 2022

Dr. Issa is my last stop! He is amazing!

Reviewed on Jun 15, 2022

I have known Dr. Issa for 9 years because he has been treating my daughter since she was 16 years old. I will not go to any other GI doctor. I trust him and trust his recommendations/treatments. I have recommended to many people to go to Dr. Issa with their issue.

Reviewed on Jun 14, 2022

Dr. Issa is the best. Assistants were too.

Reviewed on Jun 6, 2022

Dr. Issa and his staff are excellent.

Reviewed on May 31, 2022

Very professional, from the Doctor Issa and the Nurses.

Reviewed on May 31, 2022

Other medical clinics outside the CCF Network recommend Dr. Issa.

Reviewed on May 16, 2022

Dr. Issa is an excellent Dr. Took the time to talk to me and asked me if I had questions. I liked thecfact that he asked me clinical questions and my medical history while I was in the exam room before the colonoscopy began.

Reviewed on May 13, 2022

I appreciated Dr Issa's help both times that I saw him. He explained everything well and was patient with my questions. My health seems to be improving but It is a little early to know. I plan to continue my care with him and would not hesitate to recommend him to others. I appreciate that his office made two follow-up calls to me in a timely manner.

Reviewed on May 9, 2022

My eyes were watering Dr Issa took the time to wipe them for me. He is the best , has a great bed side manner!

Reviewed on May 9, 2022

Dr Isssa has been my doctor for 17 years !I I am in good hands!

Reviewed on Apr 25, 2022

Dr. Issa is outstanding - he is kind, professional, reassuring, actively listens and truly makes the patient feel like he cares and understands any concerns.

Reviewed on Apr 22, 2022

They made me feel very comfortable and relaxed. I would highly recommend Dr. Issa and his team for both Endoscopy and Colonoscopy procedures.

Reviewed on Mar 30, 2022

Doctor was great

Reviewed on Mar 23, 2022

Dr.Issa is one of the best Dr's. We as family are very happy to have him as our Dr.

Reviewed on Mar 21, 2022

I'm very happy about having Dr Issa as my endocrinologist. He saved me!

Reviewed on Mar 21, 2022

Dr. Issa was very good in every way.

Reviewed on Mar 15, 2022

Dr. Issa is a great dr. Very respectful very professional.

Reviewed on Mar 9, 2022

Office very efficient, seen promptly, physician excellent

Reviewed on Feb 28, 2022

Dr. Issa is an excellent care provider. He Is kind and patient.

Reviewed on Feb 18, 2022

Dr Issa asked me how I was doing Seemed actually interested Such a reassuring style

Reviewed on Jan 21, 2022

Only problem was that Dr Issa was running a hour behind. I didn't mind but my daughter who drove me had to get back to work. My neighbor had just gone to him on my recommendation and loved him! He's the best!

Reviewed on Jan 21, 2022

Dr. Issa is the BEST in every way

Reviewed on Jan 21, 2022

I cannot say enough about this gastroenterology center. It's a very uncomfortable, difficult exam and they couldn't have made it any more comfortable and enjoyable. I would say it was perfection from start to finish. Thanks to all of the staff & of course Dr. Issa. Give them all a big bonus!

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