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Department Gastroenterology, Hepatology & Nutrition
Primary Location North Ohio Gastroenterology
Type of Doctor Adults Only
Languages Arabic, English
Surgeon No
Locations Specialties & Treatments

Treatment & Services

  • Colonoscopy
  • Egd
  • Endoscopic Retrograde Cholangiopancreatography
  • Endoscopic Ultrasound
  • Flexible Sigmoidoscopy
View all 5 Treatment & Services +

Specialty in Diseases & Conditions

  • Bile Duct Diseases
  • Colon Polyps
  • Gastroesophageal Reflux (GERD)
  • General Gastroenterological Disorders
  • Hepatitis C
  • Pancreatic Disease
View all 6 Specialties +


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Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - MetroHealth Medical Center
Cleveland, OH USA

Residency - MetroHealth Medical Center
Internal Medicine
Cleveland, OH USA

Internship - MetroHealth Medical Center
Internal Medicine
Cleveland, OH USA

Medical Education - Aleppo University Faculty of Medicine


  • Internal Medicine
  • Internal Medicine - Gastroenterology
Research & Publications

Research & Publications

See publications for Khaled Issa, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 1/18/2022, Dr. Issa has reported no financial relationship with industry that is applicable to this listing. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

284 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.9 out of 5
Explains 4.9
Courtesy, Respect & Concern 4.9
Patient Rating of Doctor 4.9

51 Patient Comments

Reviewed on Aug 25, 2022

Dr Issa and all the nurses and Dr Kim anesthesiologist were very caring and wonderful!

Reviewed on Aug 25, 2022

No bad experience Dr. ISSA is a wonderful , compassionate Dr who cares what his patients are going through!

Reviewed on Aug 3, 2022

Dr Issa was great

Reviewed on Aug 1, 2022

Prior to Dr Issa, I had a female gastroenterologist and was worried about having a male since she retired, BUT, I will recommend Dr Issa to everyone. He is very caring and kind as well as his staff!!! I feel safe with him and his staff as my doctor!

Reviewed on Jul 22, 2022

Very good on every level. Dr. Khaled Issa is truly an excellent doctor as well as an excellent person. He was kind, compassionate and real. I highly recommend him to everyone. The staff complimented his high standards. Dr. Essa should give lessons to the rest of the Clinic on how to treat people. He is what gives the Cleveland Clinic their great reputation. Please let him know how my family and I feel about him. I have already passed his number to ten people.

Reviewed on Jul 15, 2022

My colonoscopy from beginning to end was great! The entire staff and Dr. Issa made the whole procedure very comfortable and simple. I cannot express in words how absolutely attentive, organized and kind each person that provided my care in preparation for my colonoscopy was! Dr. Issa was, as always, very comforting, kind, professional and the very best at his job!

Reviewed on Jun 30, 2022

Dr Issa and his team are amazing. He made us feel very comfortable and confident that everything was going to be OK. He is very caring and kind and calmed our fears. Dr. Issa is amazing.

Reviewed on Jun 29, 2022

I have been a patient of Dr Issa since before he joined the Cleveland Clinic. I was pleased when he joined the Cleveland Clinic so Clinic providers can see more information to help care for me.

Reviewed on Jun 15, 2022

Finally a doctor that has my best interest in mind. A breath of fresh air dealing with dr Issa.

Reviewed on Jun 15, 2022

Dr. Issa is my last stop! He is amazing!

Reviewed on Jun 15, 2022

I have known Dr. Issa for 9 years because he has been treating my daughter since she was 16 years old. I will not go to any other GI doctor. I trust him and trust his recommendations/treatments. I have recommended to many people to go to Dr. Issa with their issue.

Reviewed on Jun 14, 2022

Dr. Issa is the best. Assistants were too.

Reviewed on Jun 6, 2022

Dr. Issa and his staff are excellent.

Reviewed on May 31, 2022

Very professional, from the Doctor Issa and the Nurses.

Reviewed on May 31, 2022

Other medical clinics outside the CCF Network recommend Dr. Issa.

Reviewed on May 16, 2022

Dr. Issa is an excellent Dr. Took the time to talk to me and asked me if I had questions. I liked thecfact that he asked me clinical questions and my medical history while I was in the exam room before the colonoscopy began.

Reviewed on May 13, 2022

I appreciated Dr Issa's help both times that I saw him. He explained everything well and was patient with my questions. My health seems to be improving but It is a little early to know. I plan to continue my care with him and would not hesitate to recommend him to others. I appreciate that his office made two follow-up calls to me in a timely manner.

Reviewed on May 9, 2022

My eyes were watering Dr Issa took the time to wipe them for me. He is the best , has a great bed side manner!

Reviewed on May 9, 2022

Dr Isssa has been my doctor for 17 years !I I am in good hands!

Reviewed on Apr 25, 2022

Dr. Issa is outstanding - he is kind, professional, reassuring, actively listens and truly makes the patient feel like he cares and understands any concerns.

Reviewed on Apr 22, 2022

They made me feel very comfortable and relaxed. I would highly recommend Dr. Issa and his team for both Endoscopy and Colonoscopy procedures.

Reviewed on Mar 30, 2022

Doctor was great

Reviewed on Mar 23, 2022

Dr.Issa is one of the best Dr's. We as family are very happy to have him as our Dr.

Reviewed on Mar 21, 2022

I'm very happy about having Dr Issa as my endocrinologist. He saved me!

Reviewed on Mar 21, 2022

Dr. Issa was very good in every way.

Reviewed on Mar 15, 2022

Dr. Issa is a great dr. Very respectful very professional.

Reviewed on Mar 9, 2022

Office very efficient, seen promptly, physician excellent

Reviewed on Feb 28, 2022

Dr. Issa is an excellent care provider. He Is kind and patient.

Reviewed on Feb 18, 2022

Dr Issa asked me how I was doing Seemed actually interested Such a reassuring style

Reviewed on Jan 21, 2022

Only problem was that Dr Issa was running a hour behind. I didn't mind but my daughter who drove me had to get back to work. My neighbor had just gone to him on my recommendation and loved him! He's the best!

Reviewed on Jan 21, 2022

Dr. Issa is the BEST in every way

Reviewed on Jan 21, 2022

I cannot say enough about this gastroenterology center. It's a very uncomfortable, difficult exam and they couldn't have made it any more comfortable and enjoyable. I would say it was perfection from start to finish. Thanks to all of the staff & of course Dr. Issa. Give them all a big bonus!

Reviewed on Jan 12, 2022

Dr. Issa is very knowable and extremely helpful.

Reviewed on Jan 11, 2022

Very professional and considerate in the scheduling. Dr. Issa explains and listens.

Reviewed on Dec 27, 2021

I highly recommend Dr. Issa and his team. Great team.

Reviewed on Dec 15, 2021

Dr. Issa is very knowledgeable and willing to discuss any concerns and plans for my care.

Reviewed on Nov 30, 2021

Wonderful staff from the time you walk in till you leave. Receptionists, nurses, and Dr. Issa are personable, caring, put you at ease, ETC.. Highly recommend!

Reviewed on Nov 22, 2021

Phanamonal attention!!!!! Care provider bedside manner excellent.Very positive toward his patients. Attentive 100%

Reviewed on Nov 9, 2021

Super doctor in all aspects graded above.

Reviewed on Nov 2, 2021

Dr. Issa was excellent..thoroughly impressed and informed regarding all aspects of my situation.

Reviewed on Oct 20, 2021

It was a very good experience. It was my first time meeting Doctor Issa. I think explained very well what the cyst in my pancreas looked like and what my options are.

Reviewed on Oct 20, 2021

Excellent doctor!

Reviewed on Oct 18, 2021

I have always had a good experience with Dr. Issa, he is a wonderful doctor.

Reviewed on Oct 12, 2021

Dr. Issa impressed me as a very caring physician. It was very easy to talk with him. He was pleasant, and looked me in the eyes.He was NOT paying more attention to the computer screen than to what I was saying. Dr. Issa is an asset to the Clinic.

Reviewed on Oct 11, 2021

Friendly staff. Dr issa is the best.

Reviewed on Oct 6, 2021

He is one of the best doctors I have ever seen! Concerned about my condition, concerned about my recuperation, concerned about any possible future events. Listens! Actually ask questions and waits for a response. Considers the response, and has a solution. He's very easy to talk to. He does not make you feel inferior. He and his staff are on top of any medication that needs to be refilled.

Reviewed on Oct 6, 2021

I've recommended several of my doctors to family and friends.

Reviewed on Oct 1, 2021

Dr Issa always seems to be on top of things regarding my health

Reviewed on Oct 1, 2021

Dr. Issa was responsive informative and prompt. Outstanding physician and staff. Couldnt ask for better care.

Reviewed on Sep 28, 2021

Dr. Issa was wonderful and very kind and listened fully to all my questions and concerns

Reviewed on Sep 27, 2021

Dr. Issa was the best. Very concerned and caring. I cannot express in words how wonderful and compassionate he was.

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