Emergency icon Important Updates
Department Gastroenterology, Hepatology & Nutrition
Primary Location North Ohio Gastroenterology
Type of Doctor Adults Only
Languages Arabic, English
Surgeon No
Locations Specialties & Treatments

Treatment & Services

  • Colonoscopy
  • Endoscopic Retrograde Cholangiopancreatography (ERCP)
  • Endoscopic Ultrasound
  • Esophagogastroduodenoscopy (EGD)
  • Flexible Sigmoidoscopy
View all 5 Treatment & Services +

Specialty in Diseases & Conditions

  • Bile Duct Diseases
  • Colon Polyps
  • Gastroesophageal Reflux (GERD)
  • General Gastroenterological Disorders
  • Hepatitis C
  • Pancreatic Disease
View all 6 Specialties +


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Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - MetroHealth Medical Center
Cleveland, OH

Residency - MetroHealth Medical Center
Internal Medicine
Cleveland, OH United States

Internship - MetroHealth Medical Center
Internal Medicine
Cleveland, OH

Medical Education - Aleppo University Faculty of Medicine


  • Internal Medicine - Gastroenterology
  • Internal Medicine
Research & Publications

Research & Publications

See publications for Khaled Issa, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 3/22/2024, Dr. Issa has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

297 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.9 out of 5
Explains 4.9
Courtesy, Respect & Concern 4.9
Patient Rating of Doctor 4.9

56 Patient Comments

Reviewed on Jun 26, 2024

Loved Dr. Issa

Reviewed on May 31, 2024

Dr Issa is an incredibly compassionate and knowledgeable provider who has saved my life twice - in 1998 and again during the pandemic when he found my cancer. I love and appreciate himi wish he lived next door to me.

Reviewed on May 31, 2024

Very appreciative of Dr Issa and his staff

Reviewed on May 8, 2024

Dr Issa spent quite a bit of time with me trying to understand symptoms and solutions. He was very upfront about this being a complicated case and needed to review all previous tests.

Reviewed on May 8, 2024

I can not express enough how completely satisfied I was with Dr Issa. It was a first visit but I felt like I had been seeing Dr Issa for years. He made sure I was completely comfortable with everything we talked about and I left the office understanding what the options were. He was kind and respectful with a touch of humor. Difficult to find Dr's as caring as Dr Issa today.

Reviewed on May 6, 2024

Dr Issa is a professional. Outstanding doctor. Recommend him to all!

Reviewed on Apr 29, 2024

Dr Issa is the best.

Reviewed on Apr 24, 2024

Very impressed that he listened to my went over my concerns took time to show I was important of my care. Compared to past doctor I saw that was to busy to care .

Reviewed on Apr 9, 2024

Excellent care provided by Dr Issa and his staff

Reviewed on Apr 9, 2024

Very caring staff! Dr. Issa is the best! I have been his patient for over 20 years and have the greatest respect for him as a doctor and as a human being!

Reviewed on Apr 4, 2024

Dr. Issa was patient and showed empathy and concern for my worries. He took the time to fully explain everything to me so that I was comfortable with the procedure

Reviewed on Apr 3, 2024

Doctor Issa is a very good doctor and knows whats happening.

Reviewed on Apr 1, 2024

Doctor was great

Reviewed on Apr 1, 2024

Dr. Issa is extremely knowledgeable and skilled as a physician. Moreover, he knew my previous issues and current concerns, and tended to my needs.

Reviewed on Mar 26, 2024

Dr Issa is great!

Reviewed on Mar 20, 2024

Dr. Issa is cordial, compassionate, kind, and caring. He is a first-class physician and an amazing person.

Reviewed on Mar 14, 2024

Dr Issa is the best!!! The nurses were friendly, professional, and thorough!

Reviewed on Feb 28, 2024

I absolutely love Dr. Issa; he listens to you, explains everything thoroughly, and is professional, clear, concise, and friendly!

Reviewed on Feb 27, 2024

In simple words--team at Cleveland with Dr. Issa FANTASTIC staff

Reviewed on Feb 26, 2024

Dr. Issa and staff are the best!

Reviewed on Feb 23, 2024

Totally Phunamanul Staff & DR.

Reviewed on Feb 14, 2024

Dr. Issa is caring compassionate and takes the time to explain everything! I have been a patient of his for a number of years and will continue to do so as long as he remains in practice! Simply the best!

Reviewed on Jan 23, 2024

In my opinion Dr. Issa is one of the finest doctors that I have encountered in my 87 yrs of age.

Reviewed on Jan 22, 2024

Dr Issa & his staff always seem genuinely concerned for my health & well being

Reviewed on Jan 19, 2024

Dr. Issa a very pleasant and personable doctor. He quickly dispelled any anxiety l might have had with his upbeat attitude and reassuring explanations.

Reviewed on Jan 8, 2024

I wouldn't go anywhere else for treatment. Really like my doctor and his staff.

Reviewed on Jan 8, 2024

Dr Essa is outstanding.

Reviewed on Dec 21, 2023

Dr Issa was attentive and informative

Reviewed on Dec 18, 2023

The best Doc in town

Reviewed on Dec 18, 2023

Dr Issa was great!!!

Reviewed on Dec 13, 2023

Both Dr. Issa and his nurse Dawn were very clear in their communication with me. The doctor took the time to fully explain everything and made ample time to answer all my questions.

Reviewed on Dec 13, 2023

Dr. Issa is incredible. He saved me. The life I was living was not quality dealing with such an intense autoimmune issue but I am in remission now and I am so grateful. From the get go he had confidence this could get under control. Every other GI specialist scared me half to death and told me I'd need surgery.

Reviewed on Dec 7, 2023

Wonderful doctor. Had an emergency before me. He explained and apologized for the delay. I was glad that I wasn't the emergency, so I was happy to wait.

Reviewed on Dec 6, 2023

I newly transferred from another provider due not being heard and cared for. This experience was 100% better and I am happy I made this decision.

Reviewed on Dec 4, 2023

Dr. Issa deals with his patients in professional way. Knowledgeable and take care of his patients with respect

Reviewed on Dec 1, 2023

Dr. Issa was very professional. He's an asset to CCF.

Reviewed on Nov 22, 2023

Dr. Issa is a very good doctor

Reviewed on Oct 18, 2023

Very nice Doctor

Reviewed on Oct 17, 2023

Dr Issa is excellent Dr. Very nice

Reviewed on Oct 17, 2023

Dr Issa is just outstanding. Very thorough and thoughtful.

Reviewed on Oct 16, 2023

Dr Issa was kind caring and did an excellent job

Reviewed on Oct 9, 2023

The facility in Westlake is very "welcoming"; Dr. Izza and his staff are exemplary professionally, courteous, patient and friendly.

Reviewed on Oct 4, 2023

Dr. Issa is very professional and explains everything so you understand your progress.He is patient and listens to my concerns. I am very happy to have him as my doctor.

Reviewed on Sep 25, 2023

Dr Issa & his team are outstanding. I am so glad they are available to care for me. Thank you!

Reviewed on Sep 22, 2023

Dr is awesome and very comfortable

Reviewed on Sep 19, 2023

I think he's wonderful and has gone above most doctor's care.

Reviewed on Sep 18, 2023

I found that e-mail was the best way to communicate with the staff and Dr. Issa. The first time I called the office and left a phone mail, the staff did not return the call but when I used e-mail, I had a prompt response from the staff.

Reviewed on Sep 18, 2023

Dr. Issa was so thorough and professional.

Reviewed on Sep 5, 2023

Dr. Issa and his staff are wonderful! He listens, is kind and caring, and answers all questions.

Reviewed on Aug 21, 2023

Everyone at this appointment were very nice, very knowledgeable, and very professional.Dr. Issa was great.

Reviewed on Aug 21, 2023

Always recommend Dr Issa and Cleveland Clinic

Reviewed on Aug 15, 2023

Dr Issa is very good at what he does. I feel very comfortable with him and his staff.

Reviewed on Aug 10, 2023

Dr. Issa was wonderful, and I highly recommend him.

Reviewed on Aug 8, 2023

Doctor Issa and his staff were great!

Reviewed on Aug 8, 2023

I would highly recommend Dr.Issa and his staff to anyone looking to receive a high level of care

Reviewed on Jul 18, 2023

Dr Issa is skilled and caring. It's why I came there

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