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Department Gastroenterology, Hepatology & Nutrition
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English
Surgeon No
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus

Specialties & Treatments

Treatment & Services

  • Advanced Imaging Techniques
  • Argon Plasma Coagulation (APC)
  • Balloon-assisted Enteroscopy (Single and Double)
  • Biliary And Pancreatic Stone Therapy
  • Cancer Center
  • Capsule Endoscopy
  • Colonic Manometry
  • Colonoscopy
  • Deep Enteroscopy
  • Diagnostic Endoscopy
  • Double Balloon Enteroscopy
  • Endoscopic Cancer Therapy
  • Endoscopic Mucosal Ablative and Resection Techniques
  • Endoscopic Mucosal Resection
  • Endoscopic Retrograde Cholangiopancreatography
  • Endoscopic Therapy Of Anastamotic And Crohn's Disease Strictures
  • Endoscopic Treatment Of Strictures
  • Endoscopic Ultrasound
  • Endoscopic Ultrasound-guided Celiac Block
  • Endoscopy
  • Enteral Stent Placement
  • Esophageal Band Ligation
  • Esophageal Dilation
  • Flexible Sigmoidoscopy
  • Foreign Body Removal
  • Gastrointestinal Endoscopy
  • Gastrointestinal Exams
  • Interventional Endoscopy
  • Laparoscopy
  • Pancreaticobiliary Endoscopy
  • Percutaneous Endoscopic Gastrostomy (PEG)
  • Stents
  • Therapeutic Endoscopy
  • Wireless Capsule Endoscopy
View all 34 Treatment & Services +

Specialty in Diseases & Conditions

  • Barrett's Esophagus
  • Bile Duct Cancer
  • Bile Duct Diseases
  • Bile Duct Obstruction
  • Bile Duct Stones
  • Colon Polyps
  • Diseases of the Liver Biliary Tract and Pancreas
  • Duodenal Polyps
  • Esophageal Cancer
  • Gallbladder & Biliary Tract Disease
  • Gallbladder Disease
  • Gallstones
  • General Gastroenterological Disorders
  • Heartburn
  • Pancreatic Cancer
  • Pancreatic Disease
  • Pancreatic Stones
  • Pancreatitis
  • Small Bowel Disease
  • Stomach Cancer
  • Strictures Of The Gi Tract
View all 21 Specialties +


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Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Cleveland Clinic
Cleveland, OH USA

Residency - Montefiore Hospital/Univ. Health Center of Pittsburgh
Internal Medicine
Pittsburgh, PA USA

Medical Education - University of Rochester School of Medicine and Dentistry
Rochester, NY USA

Undergraduate - University of Rochester
Rochester, NY USA

Graduate School - Case Western Reserve University
Cleveland, OH USA

Additional Training

  • Master of Public Health, Case Western Reserve University, Cleveland, Ohio, 2003

Professional Highlights

  • American Society for Gastrointestinal Endoscopy Career Development Award, 2003


  • Internal Medicine

Specialty Interests

advanced endoscopy, advanced imaging techniques, biliary tract disease, Capsule Endoscopy, Colonoscopy, CRCP, deep enteroscopy, deep enteroscopy and interventional endoscopy, Diagnostic and therapeutic EGD (upper endoscopy) and colonoscopy, diagnostic and therapeutic endoscopy, diagnostic/therapeutic endoscopy, diseases of the small bowel, double balloon enteroscopy, Double Balloon Enteroscopy i.e DBE ( Antegrade & Retrograde ) and Wireless Capsule Endoscopy, EMR, endoscopic mucosal ablative and resection techniques, Endoscopic Ultrasonography, Endoscopic Ultrasound, Endoscopy, Endoscopic cancer therapy, ERCP, Esophageal Cancer, EUS, gastrointestinal endoscopy, general gastroenterology, Pancreatic Cancer, pancreatic disorders, pancreaticobiliary endoscopy, Pancreatitis, stenting, therapeutic endoscopy, Therapeutic endoscopy including difficult colonoscopy and polypectomy

Awards & Honors

  • University of Rochester Alumni Scholarship, University of Rochester, Rochester, N.Y., 1977-1981
  • Phi Beta Kappa, University of Rochester, Rochester, N.Y., 1980 
  • Nominated for application, Cecil Rhodes Scholarship, University of Rochester, Rochester, N.Y., 1980
  • Marshal, commencement exercises, University of Rochester, Rochester, N.Y., 1981
  • BA, summa cum laude, University of Rochester, 1981
  • Health Professions Scholarship, United States Navy, 1982-1985
  • Certificate of Merit, American College of Physicians, 1993
  • Letter of Commendation, Office of the Attending Physician, United States Capitol, 1994
  • United States Navy Commendation Medal, 1994
  • Poster of Distinction Award, Digestive Disease  Week for “Nasopharyngeal Versus Transcutaneous Monitoring During ERCP,” 1998
  • Poster of Distinction Award, Digestive Disease  Week for “Gastroenterologist-Administered Propofol for Therapeutic Upper Endoscopy,” 1999
  • Poster of Distinction Award, Digestive Disease  Week for “Graphic Display of Respiratory Activity is Superior to Pulse Oximetry and Visual Assessment in the Detection of Respiratory Compromise During Therapeutic Upper Endoscopy,” 1999
  • Reviewer citation, Gastrointestinal Endoscopy, 1999
  • Recognized for editorial excellence, Gastrointestinal Endoscopy, 2001
  • Teacher of the Year, Department of Gastroenterology, 2002

Innovations & Patents

  • Use of capnography for patient monitoring during gastrointestinal endoscopy
  • Use of computer-assisted propofol sedation for gastrointestinal endoscopy


  • American Society for Gastrointestinal Endoscopy
  • American Gastroenterological Association
  • American College of Gastroenterology
  • American College of Physicians
  • Honorary Fellow, Gastroenterology Society of Ecuador
Research & Publications

Research & Publications

See publications for John Vargo, MD, MPH.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 8/9/2022, Dr. Vargo has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Royalty Payments. Dr. Vargo receives or has the right to receive royalty payments for inventions or discoveries commercialized through the companies shown below:

  • Medtronic plc

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

144 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.9 out of 5
Explains 4.9
Courtesy, Respect & Concern 4.9
Patient Rating of Doctor 4.9

44 Patient Comments

Reviewed on Aug 29, 2022

Dr. Vargo is an amazing person who took time to make sure I knew all the options and was genuinely interested in my care.

Reviewed on Jul 12, 2022

Had a extremely good experience with Dr.John Vargo I highly recommend him to anyone and I did My Husband has became as patient of his also plus I have told family members about him excellent Dr he explains stuff very well he's talks on my level to understand everything and his bedside manner's can't be beat his personality is wonderful and you can tell he's concerned about you and he gives comfort in his tone with you he has been such a blessing to me and I just can't say enough good things about him you can really tell he loves what he does and loves helping people

Reviewed on Jul 12, 2022

I would recommend Dr John Vargo to anyone that needs his services I highly feel comfwith him and we have built a trust level I just can't say enough about him & the staff

Reviewed on Jun 2, 2022

Dr. Vargo is amazing. He spent time with my husband and I before explaining the procedure and then after letting us know what they found. Very kind and compassionate. I felt very confident that I was in great hands.

Reviewed on May 16, 2022

Dr Vargo is awesome. Great communications and care

Reviewed on May 16, 2022

Dr Vargo is excellent!

Reviewed on May 6, 2022

The doctor was excellent & very understanding of my issues.

Reviewed on Apr 8, 2022

I think the procedure went well. It was everything I expected. My doctor was very informative and caring. Looking forward to getting these stones out of my pancreas at a later date.

Reviewed on Apr 8, 2022

I've seen many drs from CC over the years and all were excellent in their field but Dr Vargo really made me feel comfortable with his warm bedside manner.

Reviewed on Apr 8, 2022

Dr. Vargo is the most caring, kind doctor I have ever had contact with. He is just fantastic.

Reviewed on Apr 6, 2022

Dr. Cargo was very engaged, friendly, put family at ease. Thoroughly explained my condition, future visits that would be required, so informative and friendly.

Reviewed on Mar 17, 2022

Each and every appointment with Dr. John Vargo I've had at the Cleveland Clinic has always exceeded my expectations. Thankful for CCF.

Reviewed on Mar 17, 2022

Accolades to Dr. John Vargo!

Reviewed on Mar 17, 2022

Dr Vargo was wonderfully both professional and friendly.

Reviewed on Mar 10, 2022

Dr.J. Vargo was outstanding, his professionalism and compassionate care were extraordinary.It is so reassuring when a physician has his clinical expertise and provides care with such kindness and empathy. He truly went above and beyond to provide me with an excellent experience. On the day of my procedure, it was very apparent that he leads and models to his team the same level of exemplary dedicated care.Thank you CCF for having physicians like Dr. J. Vargo who embody your mission of,"patients first" and give you the prestigious world wide rankings you deserve.

Reviewed on Feb 14, 2022

Dr. Vargo is excellentkind & caring yet professional + clearly explained his entire routine of my procedure.

Reviewed on Feb 14, 2022

I will highly recommend Dr. Vargo to all my family & friend for GI needs.

Reviewed on Feb 8, 2022

Dr. Vargo was amazing! He was very caring and nice and made me feel very relaxed about the procedure he was going to do. He explained everything very well before and after.

Reviewed on Feb 2, 2022

The Doctor was very nice and explained everything, he also answered all questions

Reviewed on Jan 28, 2022

Dr. Vargo and his staff always run things smoothly. They are all knowledgeable and you can expect and receive excellent care.

Reviewed on Jan 27, 2022

Dr. Cargo and his team were excellent. Felt totally comfortable and confident with their care. I highly recommend them!

Reviewed on Jan 21, 2022

Such a personable doctor!

Reviewed on Jan 21, 2022

Dr. Vargo is wonderful. He's caring, kind, knowledge and will do anything to help his patients. He always goes above and beyond. I am very lucky to have such an amazing doctor.

Reviewed on Jan 17, 2022

The providers who performed my procedure were excellent, personal, and very kind

Reviewed on Jan 7, 2022

Dr. Vargo embodies the essence of a true physician. My my first appointment was an example of an absolutely perfect experience.Dr.Vargo's professionalism and genuine and concern for me was was very impressive. His ability to explain, answer questions and establish a sense of confidence and trust was reassuring. He is a true treasure in the team of CCF caregivers.

Reviewed on Jan 6, 2022

Dr. Vargo has a fantastic attitude and is obviously highly skilled and knowledgeable. I appreciate how well he took care of me even though he was not my current doctor. I feel like my condition would have been diagnosed long ago had my previous doctor at another facility been as attentive and professional as Dr Vargo.

Reviewed on Jan 5, 2022

Dr. Cargo is the best Dr in the Clinic System.

Reviewed on Dec 14, 2021

Dr. John J. Vargo II was very informative and thorough on the procedure and had a great staff working with him.

Reviewed on Dec 13, 2021

Dr. Vargo has the best bed side manner of any physician I've ever been associated with. His kindness and care are truly genuine.

Reviewed on Dec 8, 2021

I was quite anxious but the doctor's gentle demeanor and complete description of the procedure put me at ease. I am quite grateful for this.

Reviewed on Nov 22, 2021

Dr. Vargo was SO easy to talk with! He was thorough with his explanation, even took the time to show me diagrams and explain what my condition was in a concise, non-condescending manner. He encouraged me to ask questions and seemed to deeply care about my condition, my options and providing the info about next steps and potential outcomes for me. This is rare with doctors in general but, even more rare with surgeons. I would recommend him to anyone! I feel at ease about my upcoming procedure.

Reviewed on Nov 22, 2021

Extremely good experience. I knew I was in good hands,great doctor and staff at the clinic. Dr. Vargo knew the problem I had and with his knowledge was able to take care of the problem. He followed the stomach ulser until it healed andThan dealt with the rest of the EGD complications I had. I could not have had a better doctor.

Reviewed on Nov 15, 2021

Dr Vargo is excellent. The only reason I wouldn't recommend is because it would extent the wait time even further to get an appointment.

Reviewed on Nov 9, 2021

Dr. Vargo takes very good care of me and always listens.

Reviewed on Nov 8, 2021

Dr Vargo was great, he was well informed about my problems and why I was there.

Reviewed on Nov 1, 2021

Dr. John J Vargo ll went above and beyond. He and the or team were just simply amazing. He said in the or they were going to take very good care of me and I said I know you will and I truly meant that.

Reviewed on Oct 28, 2021

Dr.John Vargo is a great Dr. He explains everything in detail and he talks & explains everything on your level and he doesn't rush you at all he has the best attitude and is a great dr . I was blessed to have him as my Dr . Thank you for being so compassionate at what you do for your patients

Reviewed on Oct 25, 2021

Dr Cargo is an excellent doctor. His office was kind and respectful.

Reviewed on Oct 25, 2021

It is very impressive that you can schedule an immediate appointment with a physician with outstanding credentials.

Reviewed on Oct 25, 2021

Dr. Vargo's care and concern was evident the moment he walked into the door until the time the appointment was over. He did not rush me and took time for all of my questions.

Reviewed on Oct 19, 2021

Dr. Vargo is the best

Reviewed on Oct 19, 2021

Great doctor in every area. The best!!

Reviewed on Sep 27, 2021

I wouldn't have any other doctor do my procedure other than Dr Vargo

Reviewed on Sep 27, 2021

I have been seeing Dr Vargo for over 5 years and can say that he is one of the best Doctors I have seen.

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