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Department Gastroenterology, Hepatology & Nutrition
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English
Surgeon No
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus

Specialties & Treatments

Treatment & Services

  • Advanced Imaging Techniques
  • Argon Plasma Coagulation (APC)
  • Balloon-assisted Enteroscopy (Single and Double)
  • Biliary And Pancreatic Stone Therapy
  • Cancer Center
  • Capsule Endoscopy
  • Colonic Manometry
  • Colonoscopy
  • Deep Enteroscopy
  • Diagnostic Endoscopy
  • Double Balloon Enteroscopy
  • Endoscopic Cancer Therapy
  • Endoscopic Mucosal Ablative and Resection Techniques
  • Endoscopic Mucosal Resection
  • Endoscopic Retrograde Cholangiopancreatography
  • Endoscopic Therapy Of Anastamotic And Crohn's Disease Strictures
  • Endoscopic Treatment Of Strictures
  • Endoscopic Ultrasound
  • Endoscopic Ultrasound-guided Celiac Block
  • Endoscopy
  • Enteral Stent Placement
  • Esophageal Band Ligation
  • Esophageal Dilation
  • Flexible Sigmoidoscopy
  • Foreign Body Removal
  • Gastrointestinal Endoscopy
  • Gastrointestinal Exams
  • Interventional Endoscopy
  • Laparoscopy
  • Pancreaticobiliary Endoscopy
  • Percutaneous Endoscopic Gastrostomy (PEG)
  • Stents
  • Therapeutic Endoscopy
  • Wireless Capsule Endoscopy
View all 34 Treatment & Services +

Specialty in Diseases & Conditions

  • Barrett's Esophagus
  • Bile Duct Cancer
  • Bile Duct Diseases
  • Bile Duct Obstruction
  • Bile Duct Stones
  • Colon Polyps
  • Diseases of the Liver Biliary Tract and Pancreas
  • Duodenal Polyps
  • Esophageal Cancer
  • Gallbladder & Biliary Tract Disease
  • Gallbladder Disease
  • Gallstones
  • General Gastroenterological Disorders
  • Heartburn
  • Pancreatic Cancer
  • Pancreatic Disease
  • Pancreatic Stones
  • Pancreatitis
  • Small Bowel Disease
  • Stomach Cancer
  • Strictures Of The Gi Tract
View all 21 Specialties +


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Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Cleveland Clinic
Cleveland, OH USA

Residency - Montefiore Hospital/Univ. Health Center of Pittsburgh
Internal Medicine
Pittsburgh, PA USA

Medical Education - University of Rochester School of Medicine and Dentistry
Rochester, NY USA

Undergraduate - University of Rochester
Rochester, NY USA

Graduate School - Case Western Reserve University
Cleveland, OH USA

Additional Training

  • Master of Public Health, Case Western Reserve University, Cleveland, Ohio, 2003

Professional Highlights

  • American Society for Gastrointestinal Endoscopy Career Development Award, 2003


  • Internal Medicine

Specialty Interests

advanced endoscopy, advanced imaging techniques, biliary tract disease, Capsule Endoscopy, Colonoscopy, CRCP, deep enteroscopy, deep enteroscopy and interventional endoscopy, Diagnostic and therapeutic EGD (upper endoscopy) and colonoscopy, diagnostic and therapeutic endoscopy, diagnostic/therapeutic endoscopy, diseases of the small bowel, double balloon enteroscopy, Double Balloon Enteroscopy i.e DBE ( Antegrade & Retrograde ) and Wireless Capsule Endoscopy, EMR, endoscopic mucosal ablative and resection techniques, Endoscopic Ultrasonography, Endoscopic Ultrasound, Endoscopy, Endoscopic cancer therapy, ERCP, Esophageal Cancer, EUS, gastrointestinal endoscopy, general gastroenterology, Pancreatic Cancer, pancreatic disorders, pancreaticobiliary endoscopy, Pancreatitis, stenting, therapeutic endoscopy, Therapeutic endoscopy including difficult colonoscopy and polypectomy

Awards & Honors

  • University of Rochester Alumni Scholarship, University of Rochester, Rochester, N.Y., 1977-1981
  • Phi Beta Kappa, University of Rochester, Rochester, N.Y., 1980 
  • Nominated for application, Cecil Rhodes Scholarship, University of Rochester, Rochester, N.Y., 1980
  • Marshal, commencement exercises, University of Rochester, Rochester, N.Y., 1981
  • BA, summa cum laude, University of Rochester, 1981
  • Health Professions Scholarship, United States Navy, 1982-1985
  • Certificate of Merit, American College of Physicians, 1993
  • Letter of Commendation, Office of the Attending Physician, United States Capitol, 1994
  • United States Navy Commendation Medal, 1994
  • Poster of Distinction Award, Digestive Disease  Week for “Nasopharyngeal Versus Transcutaneous Monitoring During ERCP,” 1998
  • Poster of Distinction Award, Digestive Disease  Week for “Gastroenterologist-Administered Propofol for Therapeutic Upper Endoscopy,” 1999
  • Poster of Distinction Award, Digestive Disease  Week for “Graphic Display of Respiratory Activity is Superior to Pulse Oximetry and Visual Assessment in the Detection of Respiratory Compromise During Therapeutic Upper Endoscopy,” 1999
  • Reviewer citation, Gastrointestinal Endoscopy, 1999
  • Recognized for editorial excellence, Gastrointestinal Endoscopy, 2001
  • Teacher of the Year, Department of Gastroenterology, 2002

Innovations & Patents

  • Use of capnography for patient monitoring during gastrointestinal endoscopy
  • Use of computer-assisted propofol sedation for gastrointestinal endoscopy


  • American Society for Gastrointestinal Endoscopy
  • American Gastroenterological Association
  • American College of Gastroenterology
  • American College of Physicians
  • Honorary Fellow, Gastroenterology Society of Ecuador
Research & Publications

Research & Publications

See publications for John Vargo, MD, MPH.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 1/4/2023, Dr. Vargo has reported no financial relationship with industry that is applicable to this listing. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

145 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.9 out of 5
Explains 4.9
Courtesy, Respect & Concern 4.9
Patient Rating of Doctor 4.9

39 Patient Comments

Reviewed on Jan 9, 2023

What I really appreciate of the Cleveland Clinic is how well organized and smooth my appointment was , from making the appointment to my Doctor's visitDr Vargo is so easy to talk with and explained everything ,so was the resident Dr

Reviewed on Jan 9, 2023

Doctor Vargo was very easy to talk with. He listened to me and explained what and how my upcoming procedure would be done. He reassured me when I asked him my concerns. I left my appointment with complete confidence in his judgment and ability. I give him a 10 star out of 10 and will highly recommend him!

Reviewed on Jan 3, 2023

Dr J Vargo is just excellent in every aspect of my care

Reviewed on Dec 22, 2022

Outstanding experience, especially with Dr. Vargo.Compassionate, courteous, extremely professional, and caring.

Reviewed on Dec 22, 2022

Can't say enough about Dr. Vargo and his team.Nothing could have been improved upon!

Reviewed on Dec 6, 2022

Dr. Vargo has an excellent presence and thus conveys confidence from the patient.

Reviewed on Nov 28, 2022

Dr Vargo was very professional, courteous and made the experience very comfortable. He listened to all of my questions and concerns and took the time to explain things to me in a way I could easily understand.

Reviewed on Nov 7, 2022

Dr. Vargo put me at ease as soon as he entered the room. He did his research on my medical history and quickly made my stress level go way down. He explained my medical issue in terms I could understand and gave me an opportunity to ask questions never making me feel rushed.

Reviewed on Nov 2, 2022

I had never met Dr Vargo prior to the morning of my colonoscopy. My goodness, he is incredible. I wish every doctor I've ever had was blessed with his bedside manner and temperament. He embodies best demonstrated practices when dealing with a patient and their family. An absolute gem of a human.

Reviewed on Oct 24, 2022

Dr. Vargo was very friendly and easy to talk to. He was very honest and walked me through my options. I will be scheduling an appt. For the procedure.

Reviewed on Oct 17, 2022

Dr Vargo was fabulous! He put me at ease, talked in a way I could understand and was clear about a path forward, which was perfect!

Reviewed on Sep 29, 2022

Dr. Vargo was very friendly and very professional. His demeanor makes you feel like you have known him for a long time.

Reviewed on Sep 29, 2022

Dr. Vargo was very personable and assuring. He makes you feel like you have been his patient for many years.

Reviewed on Sep 1, 2022

Dr Vargo is very personable and caring

Reviewed on Aug 29, 2022

Dr. Vargo is an amazing person who took time to make sure I knew all the options and was genuinely interested in my care.

Reviewed on Aug 22, 2022

Dr. Vargo is an excellent doctor, extremely knowledgable, skilled, and compassionate.

Reviewed on Jul 12, 2022

Had a extremely good experience with Dr.John Vargo I highly recommend him to anyone and I did My Husband has became as patient of his also plus I have told family members about him excellent Dr he explains stuff very well he's talks on my level to understand everything and his bedside manner's can't be beat his personality is wonderful and you can tell he's concerned about you and he gives comfort in his tone with you he has been such a blessing to me and I just can't say enough good things about him you can really tell he loves what he does and loves helping people

Reviewed on Jul 12, 2022

I would recommend Dr John Vargo to anyone that needs his services I highly feel comfwith him and we have built a trust level I just can't say enough about him & the staff

Reviewed on Jun 2, 2022

Dr. Vargo is amazing. He spent time with my husband and I before explaining the procedure and then after letting us know what they found. Very kind and compassionate. I felt very confident that I was in great hands.

Reviewed on May 16, 2022

Dr Vargo is awesome. Great communications and care

Reviewed on May 16, 2022

Dr Vargo is excellent!

Reviewed on May 6, 2022

The doctor was excellent & very understanding of my issues.

Reviewed on Apr 8, 2022

I think the procedure went well. It was everything I expected. My doctor was very informative and caring. Looking forward to getting these stones out of my pancreas at a later date.

Reviewed on Apr 8, 2022

I've seen many drs from CC over the years and all were excellent in their field but Dr Vargo really made me feel comfortable with his warm bedside manner.

Reviewed on Apr 8, 2022

Dr. Vargo is the most caring, kind doctor I have ever had contact with. He is just fantastic.

Reviewed on Apr 6, 2022

Dr. Cargo was very engaged, friendly, put family at ease. Thoroughly explained my condition, future visits that would be required, so informative and friendly.

Reviewed on Mar 17, 2022

Each and every appointment with Dr. John Vargo I've had at the Cleveland Clinic has always exceeded my expectations. Thankful for CCF.

Reviewed on Mar 17, 2022

Accolades to Dr. John Vargo!

Reviewed on Mar 17, 2022

Dr Vargo was wonderfully both professional and friendly.

Reviewed on Mar 10, 2022

Dr.J. Vargo was outstanding, his professionalism and compassionate care were extraordinary.It is so reassuring when a physician has his clinical expertise and provides care with such kindness and empathy. He truly went above and beyond to provide me with an excellent experience. On the day of my procedure, it was very apparent that he leads and models to his team the same level of exemplary dedicated care.Thank you CCF for having physicians like Dr. J. Vargo who embody your mission of,"patients first" and give you the prestigious world wide rankings you deserve.

Reviewed on Feb 14, 2022

Dr. Vargo is excellentkind & caring yet professional + clearly explained his entire routine of my procedure.

Reviewed on Feb 14, 2022

I will highly recommend Dr. Vargo to all my family & friend for GI needs.

Reviewed on Feb 8, 2022

Dr. Vargo was amazing! He was very caring and nice and made me feel very relaxed about the procedure he was going to do. He explained everything very well before and after.

Reviewed on Feb 2, 2022

The Doctor was very nice and explained everything, he also answered all questions

Reviewed on Jan 28, 2022

Dr. Vargo and his staff always run things smoothly. They are all knowledgeable and you can expect and receive excellent care.

Reviewed on Jan 27, 2022

Dr. Cargo and his team were excellent. Felt totally comfortable and confident with their care. I highly recommend them!

Reviewed on Jan 21, 2022

Such a personable doctor!

Reviewed on Jan 21, 2022

Dr. Vargo is wonderful. He's caring, kind, knowledge and will do anything to help his patients. He always goes above and beyond. I am very lucky to have such an amazing doctor.

Reviewed on Jan 17, 2022

The providers who performed my procedure were excellent, personal, and very kind

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